Cerebral ischemia combined with β-amyloid impairs spatial memory in the eight-arm radial maze task in rats

Brain Research

Volumn 1097, Issue 1, 2006, Pages 216-223

  Iwasaki, Katsunori ^a   Egashira, Nobuaki ^a   Hatip Al Khatib, Izzettin ^b   Akiyoshi, Yuki ^a   Arai, Takashi ^a   Takagaki, Yuki ^a   Watanabe, Takuya ^a   Mishima, Kenichi ^a   Fujiwara, Michihiro ^a  

^a FUKUOKA UNIVERSITY   (Japan)

^b Department of Internal Medicine   (Turkey)

Author keywords

Amyloid; Acetylcholine; Alzheimer's disease; Apoptosis; Donepezil; Spatial memory

Indexed keywords

ACETYLCHOLINE; AMYLOID BETA PROTEIN; DONEPEZIL;

ACETYLCHOLINE RELEASE; ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN HYPOXIA; BRAIN ISCHEMIA; BRAIN REGION; CONTROLLED STUDY; EVOKED RESPONSE; HIPPOCAMPUS; IN VIVO STUDY; MALE; MAZE TEST; MICRODIALYSIS; NERVE CELL; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SPATIAL MEMORY; STATISTICAL SIGNIFICANCE; STEREOTAXIC SURGERY; TASK PERFORMANCE;

AMYLOID BETA-PROTEIN; ANIMALS; BRAIN ISCHEMIA; MALE; MAZE LEARNING; MEMORY; RATS; RATS, WISTAR; SPACE PERCEPTION;

EID: 33745880715     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.04.073     Document Type: Article

References (40)

1. Banks W.A., Robinson S.M., Verma S., and Morley J.E. Efflux of human and mouse amyloid beta proteins 1-40 and 1-42 from brain: Impairment in a mouse model of Alzheimer's disease. Neuroscience 121 (2003) 487-492
2. Bertrand N., Bralet J., and Beley A. Post-ischemic regional changes in acetylcholine synthesis following transient forebrain ischemia in gerbils. Neurochem. Res. 17 (1992) 321-325
3. Cai X.D., Golde T.E., and Younkin S.G. Release of excess amyloid beta protein from a mutant amyloid beta protein precursor. Science 22 (1993) 514-516
4. Davis B.M., Mohs R.C., Greenwald B.S., Mathe A.A., Johns C.A., Horvath T.B., and Davis K.L. Clinical studies of the cholinergic deficit in Alzheimer's disease: I. Neurochemical and neuroendocrine studies. J. Am. Geriatr. Soc. 33 (1985) 741-748
5. de la Torre J.C. Impaired brain microcirculation may trigger Alzheimer's disease. Neurosci. Biobehav. Rev. 18 (1994) 397-401
6. Egashira N., Iwasaki K., Ishibashi M., Hatip-Al-Khatib I., Wolozin B., Mishima K., Irie K., and Fujiwara M. Hypoxia enhances beta-amyloid-induced apoptosis in rat cultured hippocampal neurons. Jpn. J. Pharmacol. 90 (2002) 321-327
7. Gervais F.G., Xu D., Robertson G.S., Vaillancourt J.P., Zhu Y., Huang J., LeBlanc A., Smith D., Rigby M., Shearman M.S., Clarke E.E., Zheng H., Van Der Ploeg L.H., Ruffolo S.C., Thornberry N.A., Xanthoudakis S., Zamboni R.J., Roy S., and Nicholson D.W. Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation. Cell 97 (1999) 395-406
8. Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., and Cole G. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274 (1996) 99-102
9. Ivins K.J., Thornton P.L., Rohn T.T., and Cotman C.W. Neuronal apoptosis induced by beta-amyloid is mediated by caspase-8. Neurobiol. Dis. 6 (1999) 440-449
10. Iwasaki K., Matsumoto Y., and Fujiwara M. Effect of Nebracetam on the disruption of spatial cognition in rats. Jpn. J. Pharmacol. 58 (1992) 117-126
11. Iwasaki K., Kitamura Y., Ohgami Y., Mishima K., and Fujiwara M. The disruption of spatial cognition and changes in brain amino acid, monoamine and acetylcholine in rats with transient cerebral ischemia. Brain Res. 709 (1996) 163-172
12. Iwasaki K., Sunderland T., Kusiak J.W., and Wolozin B. Changes in gene transcription during a beta-mediated cell death. Mol. Psychiatry 1 (1996) 65-71
13. Iwasaki K., Chung E.H., Egashira N., Hatip-Al-Khatib I., Mishima K., Egawa T., Irie K., and Fujiwara M. Non-NMDA mechanism in the inhibition of cellular apoptosis and memory impairment induced by repeated ischemia in rats. Brain Res. 995 (2004) 131-139
14. Iwasaki K., Hatip-Al-Khatib I., Egashira N., Akiyoshi Y., Arai T., Mishima K., Takagaki Y., Inui K., and Fujiwara M. Ovariectomy combined with amyloid (1-42 impairs memory by decreasing acetylcholine release and (7nAChR expression without induction of apoptosis in the hippocampus CA1 neurons of rats. Neurotox. Res. 6 (2004) 299-309
15. Kar S., Seto D., Gaudreau P., and Quirion R. Beta-amyloid-related peptides inhibit potassium-evoked acetylcholine release from rat hippocampal slices. J. Neurosci. 16 (1996) 1034-1040
16. Liu Q., Kawai H., and Berg D.K. Beta-amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 4734-4739
17. London E.D., Ball M.J., and Waller S.B. Nicotinic binding sites in cerebral cortex and hippocampus in Alzheimer's dementia. Neurochem. Res. 14 (1989) 745-750
18. May P.C., Gitter B.D., Waters D.C., Simmons L.K., Becker G.W., Small J.S., and Robison P.M. Beta-amyloid peptide in vitro toxicity: lot-to-lot variability. Neurobiol. Aging 13 (1992) 605-607
19. Nitta A., Itoh A., Hasegawa T., and Nabeshima T. Beta-amyloid protein-induced Alzheimer's disease animal model. Neurosci. Lett. 170 (1994) 63-66
20. Ohnishi A., Mihara M., Kamakura H., Tomono Y., Hasegawa J., Yamazaki K., Morishita N., and Tanaka T. Comparison of the pharmacokinetics of E2020, a new compound for Alzheimer's disease, in healthy young and elderly subjects. J. Clin.Pharmacol. 33 (1993) 1086-1091
21. Olton D.S., and Samuelson R.J. Remembrance of places past: spatial memory in rats. J. Exp. Psychol., Anim. Behav. Process 2 (1976) 97-116
22. Palacino J.J., Berechid B.E., Alexander P., Eckman C., Younkin S., Nye J.S., and Wolozin B. Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells. J. Biol. Chem. 275 (2000) 215-222
23. Palacino J.J., Murphy M.P., Murayama O., Iwasaki K., Fujiwara M., Takashima A., Golde T.E., and Wolozin B. Presenilin 1 regulates beta-catenin-mediated transcription in a glycogen synthase kinase-3-independent fashion. J. Biol. Chem. 276 (2001) 38563-38569
24. Paxinos G., and Watson C. The Rat Brain Stereotaxic Coordinates (1982), Academic ress, New York
25. Pike C.J., Walencewicz A.J., Glabe C.G., and Cotman C.W. In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 563 (1991) 311-314
26. Pulsinelli W.A., Brierley J.B., and Plum F. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann. Neurol. 11 (1982) 491-498
27. Sadowski M., Pankiewicz J., Scholtzova H., Li Y.S., Quartermain D., Duff K., and Wisniewski T. Links between the pathology of Alzheimer's disease and vascular dementia. Neurochem. Res. 29 (2004) 1257-1266
28. Satoh Y., Hirakura Y., Shibayama S., Hirashima N., Suzuki T., and Kirino Y. Beta-amyloid peptides inhibit acetylcholine release from cholinergic presynaptic nerve endings isolated from an electric ray. Neurosci. Lett. 302 (2001) 97-100
29. Scremin O.U., and Jenden D.J. Focal ischemia enhances choline output and decreases acetylcholine output from rat cerebral cortex. Stroke 20 (1989) 92-95
30. Shinotoh H., Aotsuka A., Fukushi K., Nagatsuka S., Tanaka N., Ota T., Tanada S., and Irie T. Effect of donepezil on brain acetylcholinesterase activity in patients with AD measured by PET. Neurology 56 (2001) 408-410
31. Shintani E.Y., and Uchida K.M. Donepezil: an anticholinesterase inhibitor for Alzheimer's disease. Am. J. Health.-Syst. Pharm. 54 (1997) 2805-2810
32. Snowdon D.A., Greiner L.H., Mortimer J.A., Riley K.P., Greiner P.A., and Markesbery W.R. Brain infarction and the clinical expression of Alzheimer disease. The Nun. Study. JAMA 277 (1997) 813-817
33. Tatebayashi Y., Miyasaka T., Chui D.H., Akagi T., Mishima K., Iwasaki K., Fujiwara M., Tanemura K., Murayama M., Ishiguro K., Planel E., Sato S., Hashikawa T., and Takashima A. Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 13896-13901
34. Ting P., Kuroiwa H., Wagner T., Fenton H., and Klatzo I. Influence of blood-brain barrier opening to proteins on development of post-ischaemic brain injury. Neurol. Res. 8 (1986) 146-151
35. Vito P., Wolozin B., Ganjei J.K., Iwasaki K., Lacana E., and D'Adamio L. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3. J. Biol. Chem. 271 (1996) 31025-31028
36. Wang H.Y., Lee D.H., D'Andrea M.R., Peterson P.A., Shank R.P., and Reitz A.B. Beta-amyloid (1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology. J. Biol. Chem. 275 (2000) 5626-5632
37. Wolozin B., Iwasaki K., Vito P., Ganjei J.K., Lacana E., Sunderland T., Zhao B., Kusiak J.W., Wasco W., and D'Adamio L. Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation. Science 274 (1996) 1710-1713
38. Yan S.D., Chen X., Fu J., Chen M., Zhu H., Roher A., Slattery T., Zhao L., Nagashima M., Morser J., Migheli A., Nawroth P., Stern D., and Schmidt A.M. RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature 382 (1996) 685-691
39. Yan S.D., Fu J., Soto C., Chen X., Zhu H., Al-Mohanna F., Collison K., Zhu A., Stern E., Saido T., Tohyama M., Ogawa S., Roher A., and Stern D. An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease. Nature 389 (1997) 689-695
40. Yankner B.A., Duffy L.K., and Kirchner D.A. Neurotropic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science 250 (1990) 279-282