-
1
-
-
0036669881
-
Amyloid-β oligomers: Their production, toxicity and therapeutic inhibition
-
Walsh DM, Klyubin I, Fadeeva JV, Rowan MJ, Selkoe DJ. Amyloid-β oligomers: their production, toxicity and therapeutic inhibition. Biochem Soc Trans. 2002;30:552-557.
-
(2002)
Biochem Soc Trans
, vol.30
, pp. 552-557
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Rowan, M.J.4
Selkoe, D.J.5
-
2
-
-
4644293577
-
Conformation-dependent antibodies target diseases of protein misfolding
-
Glabe CG. Conformation-dependent antibodies target diseases of protein misfolding. Trends Biochem Sci. 2004;29:542-547.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 542-547
-
-
Glabe, C.G.1
-
3
-
-
0025992417
-
In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity
-
Pike CJ, Walencewicz AJ, Glabe CG, Cotman CW. In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 1991;563:311-314.
-
(1991)
Brain Res
, vol.563
, pp. 311-314
-
-
Pike, C.J.1
Walencewicz, A.J.2
Glabe, C.G.3
Cotman, C.W.4
-
4
-
-
0027447286
-
Neurodegeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state
-
Pike CJ, Burdick D, Walencewicz AJ, Glabe CG, Cotman CW. Neurodegeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state. J Neurosci. 1993;13:1676-1687.
-
(1993)
J Neurosci
, vol.13
, pp. 1676-1687
-
-
Pike, C.J.1
Burdick, D.2
Walencewicz, A.J.3
Glabe, C.G.4
Cotman, C.W.5
-
5
-
-
0028180518
-
A model for β-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer disease
-
Hensley K, Carney JM, Mattson MP, Aksenova M, Harris M, Wu JF, et al. A model for β-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer disease. Proc Natl Acad Sci U S A. 1994;91: 3270-3274.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 3270-3274
-
-
Hensley, K.1
Carney, J.M.2
Mattson, M.P.3
Aksenova, M.4
Harris, M.5
Wu, J.F.6
-
6
-
-
0028172886
-
β-Amyloid neurotoxicity requires fibril formation and is inhibited by Congo red
-
Lorenzo A, Yankner BA. β-Amyloid neurotoxicity requires fibril formation and is inhibited by Congo red. Proc Natl Acad Sci U S A. 1994;91:12243-12247.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 12243-12247
-
-
Lorenzo, A.1
Yankner, B.A.2
-
7
-
-
0037220599
-
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by β-amyloid fibrils
-
Ferrari GVDe, Chacon MA, Barria MI, Garrido JL, Godoy JA, Olivares G, et al. Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by β-amyloid fibrils. Mol Psychiatry. 2003;8:195-208.
-
(2003)
Mol Psychiatry
, vol.8
, pp. 195-208
-
-
Ferrari, G.V.D.1
Chacon, M.A.2
Barria, M.I.3
Garrido, J.L.4
Godoy, J.A.5
Olivares, G.6
-
8
-
-
0032590054
-
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
Mclean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K, et al. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol. 1999;46:860-866.
-
(1999)
Ann Neurol
, vol.46
, pp. 860-866
-
-
Mclean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
-
9
-
-
0030612033
-
APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1
-
Irizarry MC, McNamara M, Fedorchak K, Hsiao K, Hyman BT. APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1. J Neuropathol Exp Neurol. 1997;56:965-973.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 965-973
-
-
Irizarry, M.C.1
McNamara, M.2
Fedorchak, K.3
Hsiao, K.4
Hyman, B.T.5
-
10
-
-
0035863055
-
Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease
-
Kawarabayashi T, Younkin LH, Saido TC, Shoji M, Hsiao K, Younkin SG. Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J Neurosci. 2001;21:372-381.
-
(2001)
J Neurosci
, vol.21
, pp. 372-381
-
-
Kawarabayashi, T.1
Younkin, L.H.2
Saido, T.C.3
Shoji, M.4
Hsiao, K.5
Younkin, S.G.6
-
11
-
-
0036913139
-
Amyloid cored plaques in Tg2576 transgenic mice are characterized by giant plaques, slightly activated microglia, and the lack of paired helical filament-typed, dystrophic neuritis
-
Sasaki A, Shoji M, Harigaya Y, Kawarabayashi T, Ikeda M, Naito M, et al. Amyloid cored plaques in Tg2576 transgenic mice are characterized by giant plaques, slightly activated microglia, and the lack of paired helical filament-typed, dystrophic neuritis. Virchows Arch. 2002;441:358-367.
-
(2002)
Virchows Arch
, vol.441
, pp. 358-367
-
-
Sasaki, A.1
Shoji, M.2
Harigaya, Y.3
Kawarabayashi, T.4
Ikeda, M.5
Naito, M.6
-
12
-
-
0036489445
-
The relationship between Aβ and memory in the Tg2576 mouse model of Alzheimer's disease
-
Westerman MA, Cooper-Blacketer D, Mariash A, Kotilinek L, Kawarabayashi T, Younkin LH, et al. The relationship between Aβ and memory in the Tg2576 mouse model of Alzheimer's disease. J Neurosci. 2002;22:1858-1867.
-
(2002)
J Neurosci
, vol.22
, pp. 1858-1867
-
-
Westerman, M.A.1
Cooper-Blacketer, D.2
Mariash, A.3
Kotilinek, L.4
Kawarabayashi, T.5
Younkin, L.H.6
-
13
-
-
0035297712
-
Targeting small Aβ oligomers: The solution to an Alzheimer's disease conundrum?
-
Klein WL, Krafft GA, Finch CE. Targeting small Aβ oligomers: the solution to an Alzheimer's disease conundrum? Trends Neurosci. 2001;24:219-223.
-
(2001)
Trends Neurosci
, vol.24
, pp. 219-223
-
-
Klein, W.L.1
Krafft, G.A.2
Finch, C.E.3
-
14
-
-
0033570337
-
Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
-
Hartley DM, Walsh DM, Ye CP, Diehl T, Vasquez S, Vassilev PM, et al. Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J Neurosci. 1999;19:8876-8884.
-
(1999)
J Neurosci
, vol.19
, pp. 8876-8884
-
-
Hartley, D.M.1
Walsh, D.M.2
Ye, C.P.3
Diehl, T.4
Vasquez, S.5
Vassilev, P.M.6
-
15
-
-
0037200117
-
Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability
-
Dahlgren KN, Manelli AM, Stine WB Jr, Baker LK, Krafft GA, LaDu MJ. Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability. J Biol Chem. 2002;277:32046-32053.
-
(2002)
J Biol Chem
, vol.277
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Stine Jr, W.B.3
Baker, L.K.4
Krafft, G.A.5
LaDu, M.J.6
-
16
-
-
0037931149
-
Specific compositions of amyloid-beta peptides as the determinant of toxic beta-aggregation
-
Yoshiike Y, Chui DH, Akagi T, Tanaka N, Takashima A. Specific compositions of amyloid-beta peptides as the determinant of toxic beta-aggregation. J Biol Chem. 2003; 278:23648-23655.
-
(2003)
J Biol Chem
, vol.278
, pp. 23648-23655
-
-
Yoshiike, Y.1
Chui, D.H.2
Akagi, T.3
Tanaka, N.4
Takashima, A.5
-
17
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, et al. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature. 2002;416:535-539.
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
-
18
-
-
21044453723
-
Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo
-
Klyubin I, Walsh DM, Lemere CA, Cullen WK, Shankar GM, Betts V, et al. Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo. Nat Med. 2005;11:556-561.
-
(2005)
Nat Med
, vol.11
, pp. 556-561
-
-
Klyubin, I.1
Walsh, D.M.2
Lemere, C.A.3
Cullen, W.K.4
Shankar, G.M.5
Betts, V.6
-
19
-
-
16644379264
-
Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function
-
Cleary JP, Walsh DM, Hofmeister JJ, Shankar GM, Kuskowski MA, Selkoe DJ, et al. Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function. Nat Neurosci. 2005;8:79-84.
-
(2005)
Nat Neurosci
, vol.8
, pp. 79-84
-
-
Cleary, J.P.1
Walsh, D.M.2
Hofmeister, J.J.3
Shankar, G.M.4
Kuskowski, M.A.5
Selkoe, D.J.6
-
20
-
-
33745880715
-
Cerebral ischemia combined with betaamyloid impairs spatial memory in the eight-arm radial maze task in rats
-
Iwasaki K, Egashira N, Hatip-Al-Khatib I, Akiyoshi Y, Arai T, Takagaki Y, et al. Cerebral ischemia combined with betaamyloid impairs spatial memory in the eight-arm radial maze task in rats. Brain Res. 2006;1097:216-223.
-
(2006)
Brain Res
, vol.1097
, pp. 216-223
-
-
Iwasaki, K.1
Egashira, N.2
Hatip-Al-Khatib, I.3
Akiyoshi, Y.4
Arai, T.5
Takagaki, Y.6
-
21
-
-
0031054674
-
Brain infarction and the clinical expression of Alzheimer disease. The Nun Study
-
Snowdon DA, Greiner LH, Mortimer JA, Riley KP, Greiner PA, Markesbery MR. Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. JAMA. 1997;277:813-817.
-
(1997)
JAMA
, vol.277
, pp. 813-817
-
-
Snowdon, D.A.1
Greiner, L.H.2
Mortimer, J.A.3
Riley, K.P.4
Greiner, P.A.5
Markesbery, M.R.6
-
22
-
-
0036956436
-
Hypoxia enhances beta-amyloid-induced apoptosis in rat cultured hippocampal neurons
-
Egashira N, Iwasaki K, Ishibashi M, Hatip-Al-Khatib I, Wolozin B, Mishima K, et al. Hypoxia enhances beta-amyloid-induced apoptosis in rat cultured hippocampal neurons. Jpn J Pharmacol. 2002;90:321-327.
-
(2002)
Jpn J Pharmacol
, vol.90
, pp. 321-327
-
-
Egashira, N.1
Iwasaki, K.2
Ishibashi, M.3
Hatip-Al-Khatib, I.4
Wolozin, B.5
Mishima, K.6
-
24
-
-
0027955667
-
Temporal changes in extracellular acetylcholine and CA1 pyramidal cells in gerbil hippocampus following transient cerebral ischemia
-
Ishimaru H, Takahashi A, Ikarashi Y, Maruyama Y. Temporal changes in extracellular acetylcholine and CA1 pyramidal cells in gerbil hippocampus following transient cerebral ischemia. Brain Res. 1994;639:66-72.
-
(1994)
Brain Res
, vol.639
, pp. 66-72
-
-
Ishimaru, H.1
Takahashi, A.2
Ikarashi, Y.3
Maruyama, Y.4
-
25
-
-
11844300395
-
Soluble Abeta oligomers ultrastructurally localize to cell processes and might be related to synaptic dysfunction in Alzheimer's disease brain
-
Kokubo H, Kayed R, Glabe CG, Yamaguchi H. Soluble Abeta oligomers ultrastructurally localize to cell processes and might be related to synaptic dysfunction in Alzheimer's disease brain. Brain Res. 2005;1031:222-228.
-
(2005)
Brain Res
, vol.1031
, pp. 222-228
-
-
Kokubo, H.1
Kayed, R.2
Glabe, C.G.3
Yamaguchi, H.4
-
26
-
-
0021707433
-
Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
-
Benveniste H, Drejer J, Schousboe A, Diemer NH. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem. 1984;43:1369-1374.
-
(1984)
J Neurochem
, vol.43
, pp. 1369-1374
-
-
Benveniste, H.1
Drejer, J.2
Schousboe, A.3
Diemer, N.H.4
-
27
-
-
0021829328
-
Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro
-
Drejer J, Benveniste H, Diemer NH, Schousboe A. Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro. J Neurochem. 1985;45:145-151.
-
(1985)
J Neurochem
, vol.45
, pp. 145-151
-
-
Drejer, J.1
Benveniste, H.2
Diemer, N.H.3
Schousboe, A.4
-
28
-
-
0034899730
-
Amyloid beta proteins inhibit Cl(-)-ATPase activity in cultured rat hippocampal neurons
-
Yagyu K, Kitagawa K, Irie T, Wu B, Zeng XT, Hattori N, et al. Amyloid beta proteins inhibit Cl(-)-ATPase activity in cultured rat hippocampal neurons. J Neurochem. 2001;78:569-576.
-
(2001)
J Neurochem
, vol.78
, pp. 569-576
-
-
Yagyu, K.1
Kitagawa, K.2
Irie, T.3
Wu, B.4
Zeng, X.T.5
Hattori, N.6
-
29
-
-
33646091744
-
Chloride-dependency of amyloid beta protein-induced enhancement of glutamate neurotoxicity in cultured rat hippocampal neurons
-
Zhang NY, Kitagawa K, Wu B, Xiong ZM, Otani H, Inagaki C. Chloride-dependency of amyloid beta protein-induced enhancement of glutamate neurotoxicity in cultured rat hippocampal neurons. Neurosci Lett. 2006;399:175-180.
-
(2006)
Neurosci Lett
, vol.399
, pp. 175-180
-
-
Zhang, N.Y.1
Kitagawa, K.2
Wu, B.3
Xiong, Z.M.4
Otani, H.5
Inagaki, C.6
-
30
-
-
0344872608
-
Non-NMDA mechanism in the inhibition of cellular apoptosis and memory impairment induced by repeated ischemia in rats
-
Iwasaki K, Chung EH, Egashira N, Hatip-Al-Khatib I, Mishima K, Egawa T, et al. Non-NMDA mechanism in the inhibition of cellular apoptosis and memory impairment induced by repeated ischemia in rats. Brain Res. 2004;995:131-139.
-
(2004)
Brain Res
, vol.995
, pp. 131-139
-
-
Iwasaki, K.1
Chung, E.H.2
Egashira, N.3
Hatip-Al-Khatib, I.4
Mishima, K.5
Egawa, T.6
-
31
-
-
33644910893
-
Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell death in rats
-
Tanaka S, Ide M, Shibutani T, Ohtaki H, Numazawa S, Shioda S, et al. Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell death in rats. J Neurosci Res. 2006;83:557-566.
-
(2006)
J Neurosci Res
, vol.83
, pp. 557-566
-
-
Tanaka, S.1
Ide, M.2
Shibutani, T.3
Ohtaki, H.4
Numazawa, S.5
Shioda, S.6
-
32
-
-
0036093483
-
Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury
-
Bolay H, Gursoy-Ozdemir Y, Sara Y, Onur R, Can A, Dalkara T. Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury. Stroke. 2002;33:1369-1375.
-
(2002)
Stroke
, vol.33
, pp. 1369-1375
-
-
Bolay, H.1
Gursoy-Ozdemir, Y.2
Sara, Y.3
Onur, R.4
Can, A.5
Dalkara, T.6
-
33
-
-
24744472049
-
β-Amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease
-
Kelly BL, Vassar R, Ferreira A. β-Amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease. J Biol Chem. 2005;280:31746-31753.
-
(2005)
J Biol Chem
, vol.280
, pp. 31746-31753
-
-
Kelly, B.L.1
Vassar, R.2
Ferreira, A.3
-
34
-
-
2442453242
-
Comparison of the effect of TAK-147 (zanapezil) and E-2020 (donepezil) on extracellular acetylcholine level and blood flow in the ventral hippocampus of freely moving rats
-
Hatip-Al-Khatib I, Takashi A, Egashira N, Iwasaki K, Fujiwara M. Comparison of the effect of TAK-147 (zanapezil) and E-2020 (donepezil) on extracellular acetylcholine level and blood flow in the ventral hippocampus of freely moving rats. Brain Res. 2004;1012:169-176.
-
(2004)
Brain Res
, vol.1012
, pp. 169-176
-
-
Hatip-Al-Khatib, I.1
Takashi, A.2
Egashira, N.3
Iwasaki, K.4
Fujiwara, M.5
-
35
-
-
33748795335
-
Comparative studies of huperzine A, donepezil, and rivastigmine on brain acetylcholine, dopamine, norepinephrine, and 5-hydroxytryptamine levels in freely-moving rats
-
Liang YQ, Tang XC. Comparative studies of huperzine A, donepezil, and rivastigmine on brain acetylcholine, dopamine, norepinephrine, and 5-hydroxytryptamine levels in freely-moving rats. Acta Pharmacol Sin. 2006;27:1127-1136.
-
(2006)
Acta Pharmacol Sin
, vol.27
, pp. 1127-1136
-
-
Liang, Y.Q.1
Tang, X.C.2
-
36
-
-
34147128293
-
Nilvadipine Prevents the Impairment of Spatial Memory Induced by Cerebral Ischemia Combined with beta-Amyloid in Rats
-
Iwasaki K, Egashira N, Takagaki Y, Yoshimitsu Y, Hatip-AlKhatib I, Mishima K, et al. Nilvadipine Prevents the Impairment of Spatial Memory Induced by Cerebral Ischemia Combined with beta-Amyloid in Rats. Biol Pharm Bull. 2007;30:698-701.
-
(2007)
Biol Pharm Bull
, vol.30
, pp. 698-701
-
-
Iwasaki, K.1
Egashira, N.2
Takagaki, Y.3
Yoshimitsu, Y.4
Hatip-AlKhatib, I.5
Mishima, K.6
-
37
-
-
33748792254
-
beta-Amyloid-induced dynamin 1 degradation is mediated by N-methyl-D-aspartate receptors in hippocampal neurons
-
Kelly BL, Ferreira A. beta-Amyloid-induced dynamin 1 degradation is mediated by N-methyl-D-aspartate receptors in hippocampal neurons. J Biol Chem. 2006;281:28079-28089.
-
(2006)
J Biol Chem
, vol.281
, pp. 28079-28089
-
-
Kelly, B.L.1
Ferreira, A.2
|