메뉴 건너뛰기




Volumn 37, Issue 7, 2004, Pages 1037-1050

The effects of meso-2,3-dimercaptosuccinic acid and oligomeric procyanidins on acute lead neurotoxicity in rat hippocampus

Author keywords

Antioxidant; Apoptosis; Chelating; DMSA; Free radicals; Hippocampus; Lead neurotoxicity; OPC; Oxidative stress

Indexed keywords

LEAD; METAL DERIVATIVE; OLIGOMERIC PROCYANIDIN; PROCYANIDIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; SUCCIMER; UNCLASSIFIED DRUG;

EID: 4444269010     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.06.037     Document Type: Article
Times cited : (43)

References (73)
  • 2
    • 0029960668 scopus 로고    scopus 로고
    • Results of lead research: Prenatal exposure and neurological consequences
    • R.A. Goyer Results of lead research: prenatal exposure and neurological consequences Environ. Health Perspect. 104 1996 1050 1054
    • (1996) Environ. Health Perspect. , vol.104 , pp. 1050-1054
    • Goyer, R.A.1
  • 3
    • 0029986147 scopus 로고    scopus 로고
    • Relationships among blood lead levels, iron deficiency, and cognitive development in two-year-old children
    • H.A. Ruff, M.E. Markowitz, P.E. Bijur, and J.F. Rosen Relationships among blood lead levels, iron deficiency, and cognitive development in two-year-old children Environ. Health Perspect. 104 1996 180 185
    • (1996) Environ. Health Perspect. , vol.104 , pp. 180-185
    • Ruff, H.A.1    Markowitz, M.E.2    Bijur3    Rosen, J.F.P.E.4
  • 5
    • 0022737996 scopus 로고
    • Time of exposure and time of testing in developmental neurotoxicology
    • P.M. Rodier Time of exposure and time of testing in developmental neurotoxicology Neurotoxicology 7 1986 69 76
    • (1986) Neurotoxicology , vol.7 , pp. 69-76
    • Rodier, P.M.1
  • 6
    • 0026667685 scopus 로고
    • Mechanisms of Pb neurotoxicity, or looking beyond the lamppost
    • E.K. Silbergeld Mechanisms of Pb neurotoxicity, or looking beyond the lamppost FASEB J. 6 1992 3201 3206
    • (1992) FASEB J. , vol.6 , pp. 3201-3206
    • Silbergeld, E.K.1
  • 7
    • 0029118303 scopus 로고
    • Inorganic lead may inhibit neurite development in cultured rat hippocampal neurons through hyperphosphorylation
    • M. Kern, and G. Audesirk Inorganic lead may inhibit neurite development in cultured rat hippocampal neurons through hyperphosphorylation Toxicol. Appl. Pharmacol. 134 1995 111 123
    • (1995) Toxicol. Appl. Pharmacol. , vol.134 , pp. 111-123
    • Kern1    Audesirk, G.M.2
  • 8
    • 0026666541 scopus 로고
    • Altered sensitivity to NMDA following developmental lead exposure in rats
    • T.L. Petit, J.C. LeBoutillier, and W.J. Brooks Altered sensitivity to NMDA following developmental lead exposure in rats Physiol. Behav. 52 1992 687 693
    • (1992) Physiol. Behav. , vol.52 , pp. 687-693
    • Petit, T.L.1    Leboutillier2    Brooks, W.J.J.C.3
  • 9
    • 0030923445 scopus 로고    scopus 로고
    • Relationships between Pb-induced changes in neurotransmitter system function and behavioral toxicity
    • D.A. Cory-Slechta Relationships between Pb-induced changes in neurotransmitter system function and behavioral toxicity Neurotoxicology 18 1997 673 688
    • (1997) Neurotoxicology , vol.18 , pp. 673-688
    • Cory-Slechta, D.A.1
  • 11
    • 0025811270 scopus 로고
    • Lead-induced tissue fatty acid alterations and lipid peroxidation
    • L.J. Lawton, and W.E. Donaldson Lead-induced tissue fatty acid alterations and lipid peroxidation Biol. Trace Elem. Res. 28 1991 83 97
    • (1991) Biol. Trace Elem. Res. , vol.28 , pp. 83-97
    • Lawton1    Donaldson, W.E.L.J.2
  • 12
    • 0028296692 scopus 로고
    • Lipoperoxidative damage on lead exposure in rat brain and its implications on membrane bound enzymes
    • R. Sandhir, D. Julka, and K.D. Gill Lipoperoxidative damage on lead exposure in rat brain and its implications on membrane bound enzymes Pharmacol. Toxicol. 74 1994 66 71
    • (1994) Pharmacol. Toxicol. , vol.74 , pp. 66-71
    • Sandhir, R.1    Julka2    Gill, K.D.D.3
  • 13
    • 0028945122 scopus 로고
    • Effect of lead on lipid peroxidation in livers of rats
    • R. Sandhir, and K.D. Gill Effect of lead on lipid peroxidation in livers of rats Biol. Trace Elem. Res. 48 1995 91 97
    • (1995) Biol. Trace Elem. Res. , vol.48 , pp. 91-97
    • Sandhir1    Gill, K.D.R.2
  • 14
    • 0032798931 scopus 로고    scopus 로고
    • Lead intoxication: Antioxidant defenses and oxidative damage in rat brain
    • V.N. Adonaylo, and P.I. Oteiza Lead intoxication: antioxidant defenses and oxidative damage in rat brain Toxicology 135 1999 77 85
    • (1999) Toxicology , vol.135 , pp. 77-85
    • Adonaylo1    Oteiza, P.I.V.N.2
  • 16
    • 0019366249 scopus 로고
    • Lead toxicity related to glutathione metabolism
    • J.M. Hsu Lead toxicity related to glutathione metabolism J. Nutr. 111 1981 26 33
    • (1981) J. Nutr. , vol.111 , pp. 26-33
    • Hsu, J.M.1
  • 17
    • 51249177905 scopus 로고
    • Changes in organ nonprotein sulfhydryl and glutathione concentrations during acute and chronic administration of inorganic lead to chicks
    • C. McGowan, and W.E. Donaldson Changes in organ nonprotein sulfhydryl and glutathione concentrations during acute and chronic administration of inorganic lead to chicks Biol. Trace Elem. Res. 10 1986 37 46
    • (1986) Biol. Trace Elem. Res. , vol.10 , pp. 37-46
    • McGowan1    Donaldson, W.E.C.2
  • 19
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: A discourse on the bcl-2 family and cell death
    • E. Yang, and J. Korsmeyer Molecular thanatopsis: a discourse on the bcl-2 family and cell death Blood 88 1996 336 401
    • (1996) Blood , vol.88 , pp. 336-401
    • Yang1    Korsmeyer, J.E.2
  • 20
    • 0030302459 scopus 로고    scopus 로고
    • Lead promotes apoptosis in newborn rat cerebellar neurons: Pathological implications
    • A. Oberto, N. Marks, H.L. Evans, and A. Guidotti Lead promotes apoptosis in newborn rat cerebellar neurons: pathological implications J. Pharmacol. Exp. Ther. 279 1996 435 442
    • (1996) J. Pharmacol. Exp. Ther. , vol.279 , pp. 435-442
    • Oberto, A.1    Marks, N.2    Evans3    Guidotti, A.H.L.4
  • 21
    • 0030964555 scopus 로고    scopus 로고
    • Functional alterations and apoptotic cell death in the retina following developmental or adult lead exposure
    • D.A. Fox, M.L. Campbell, and Y.S. Blocker Functional alterations and apoptotic cell death in the retina following developmental or adult lead exposure Neurotoxicology 18 1997 645 664
    • (1997) Neurotoxicology , vol.18 , pp. 645-664
    • Fox, D.A.1    Campbell2    Blocker, Y.S.M.L.3
  • 22
    • 17044458697 scopus 로고    scopus 로고
    • Lead induced alterations in retinal cGMP phosphodiesterase trigger calcium overload, mitochondrial dysfunction and photoreceptor apoptosis
    • D.A. Fox, L. He, A.N. Poblenz, C.J. Medrano, Y.S. Blocker, and D. Srivastava Lead induced alterations in retinal cGMP phosphodiesterase trigger calcium overload, mitochondrial dysfunction and photoreceptor apoptosis Toxicol. Lett. 103 1998 359 361
    • (1998) Toxicol. Lett. , vol.103 , pp. 359-361
    • Fox, D.A.1    He, L.2    Poblenz, A.N.3    Medrano, C.J.4    Blocker5    Srivastava, D.Y.S.6
  • 23
    • 0034697363 scopus 로고    scopus 로고
    • Lead and calcium produce rod photoreceptor cell apoptosis by opening the mitochondrial permeability transition pore
    • L. He, A.T. Poblenz, C.J. Medrano, and D.A. Fox Lead and calcium produce rod photoreceptor cell apoptosis by opening the mitochondrial permeability transition pore J. Biol. Chem. 275 2000 12175 12184
    • (2000) J. Biol. Chem. , vol.275 , pp. 12175-12184
    • He, L.1    Poblenz, A.T.2    Medrano3    Fox, D.A.C.J.4
  • 24
    • 0034992436 scopus 로고    scopus 로고
    • Postnatal inorganic lead exposure decreases the number of spontaneously active midbrain dopamine neurons in the rat
    • M. Tavakoli-Nezhad, A.J. Barron, and D.K. Pitts Postnatal inorganic lead exposure decreases the number of spontaneously active midbrain dopamine neurons in the rat NeuroToxicology 22 2001 259 269
    • (2001) NeuroToxicology , vol.22 , pp. 259-269
    • Tavakoli-Nezhad, M.1    Barron2    Pitts, D.K.A.J.3
  • 25
    • 0030056351 scopus 로고    scopus 로고
    • Cholinergic denervation-like changes in rat hippocampus developmental lead exposure
    • H. Bielarczyk, X. Tian, and J.B. Suszkiw Cholinergic denervation-like changes in rat hippocampus developmental lead exposure Brain Res. 708 1996 108 115
    • (1996) Brain Res. , vol.708 , pp. 108-115
    • Bielarczyk, H.1    Tian2    Suszkiw, J.B.X.3
  • 26
    • 0034008076 scopus 로고    scopus 로고
    • Effects of chronic lead exposure on short-term and long-term depression in area CA1 of the rat hippocampus in vivo
    • D.Y. Ruan, K.F. Yan, S.Y. Ge, Y.Z. Xu, J.T. Chen, and M. Wang Effects of chronic lead exposure on short-term and long-term depression in area CA1 of the rat hippocampus in vivo Chemosphere 41 2000 165 171
    • (2000) Chemosphere , vol.41 , pp. 165-171
    • Ruan, D.Y.1    Yan, K.F.2    Ge, S.Y.3    Xu, Y.Z.4    Chen5    Wang, M.J.T.6
  • 27
    • 0037162630 scopus 로고    scopus 로고
    • Investigation of acute lead poisoning on apoptosis in rat hippocampus in vivo
    • A.M. Sharifi, S. Baniasadi, M. Jorjani, F. Rahimi, and M. Bakhshayesh Investigation of acute lead poisoning on apoptosis in rat hippocampus in vivo Neurosci. Lett. 329 2002 45 48
    • (2002) Neurosci. Lett. , vol.329 , pp. 45-48
    • Sharifi, A.M.1    Baniasadi, S.2    Jorjani, M.3    Rahimi4    Bakhshayesh, M.F.5
  • 28
    • 0025764224 scopus 로고
    • Chronic lead-poisoning treated with dimercaptosuccinic acid
    • P. Grandjean, I.A. Jacobsen, and P.J. Jorgensen Chronic lead-poisoning treated with dimercaptosuccinic acid Pharmacol. Toxicol. 68 1991 266 269
    • (1991) Pharmacol. Toxicol. , vol.68 , pp. 266-269
    • Grandjean, P.1    Jacobsen2    Jorgensen, P.J.I.A.3
  • 30
    • 0000025295 scopus 로고    scopus 로고
    • Principles and recent developments in chelation treatment of metal intoxication
    • O. Andersen Principles and recent developments in chelation treatment of metal intoxication Chem. Rev. 99 1999 2683 2710
    • (1999) Chem. Rev. , vol.99 , pp. 2683-2710
    • Andersen, O.1
  • 32
    • 0033929832 scopus 로고    scopus 로고
    • Safety and efficacy of meso-2,3-dimercaptosuccinic acid (DMSA) in children with elevated blood lead concentrations
    • J.J. Chisolm Safety and efficacy of meso-2,3-dimercaptosuccinic acid (DMSA) in children with elevated blood lead concentrations J. Toxicol. Clin. Toxicol. 38 2000 365 375
    • (2000) J. Toxicol. Clin. Toxicol. , vol.38 , pp. 365-375
    • Chisolm, J.J.1
  • 33
    • 0028542424 scopus 로고
    • Oral chelators for childhood lead poisoning
    • E.L. Liebelt, and M.W. Shannon Oral chelators for childhood lead poisoning Pediatr. Ann. 23 1994 616 626
    • (1994) Pediatr. Ann. , vol.23 , pp. 616-626
    • Liebelt1    Shannon, M.W.E.L.2
  • 34
    • 0031850115 scopus 로고    scopus 로고
    • Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead-exposed rats
    • H. Gurer, H. Ozgunes, R. Neal, D.R. Spitz, and N. Ercal Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead-exposed rats Toxicology 128 1998 181 189
    • (1998) Toxicology , vol.128 , pp. 181-189
    • Gurer, H.1    Ozgunes, H.2    Neal, R.3    Spitz4    Ercal, N.D.R.5
  • 37
    • 0034520371 scopus 로고    scopus 로고
    • Molecular aspects of procyanidin biological activity: Disease preventative and therapeutic potentials
    • H. Moini, G. Rimbach, and L. Packer Molecular aspects of procyanidin biological activity: disease preventative and therapeutic potentials Drug Metab. Drug Interact. 17 2000 237 259
    • (2000) Drug Metab. Drug Interact. , vol.17 , pp. 237-259
    • Moini, H.1    Rimbach2    Packer, L.G.3
  • 39
    • 0032819143 scopus 로고    scopus 로고
    • Increase of antioxidative potential of rat plasma by oral administration of proanthocyanidin-rich extract from grape seeds
    • T. Koga, K. Moro, K. Nakamori, J. Yamakoshi, H. Hosoyama, S. Kataoka, and T. Ariga Increase of antioxidative potential of rat plasma by oral administration of proanthocyanidin-rich extract from grape seeds J. Agric. Food Chem. 47 1999 1892 1897
    • (1999) J. Agric. Food Chem. , vol.47 , pp. 1892-1897
    • Koga, T.1    Moro, K.2    Nakamori, K.3    Yamakoshi, J.4    Hosoyama, H.5    Kataoka6    Ariga, T.S.7
  • 41
    • 0035024843 scopus 로고    scopus 로고
    • Effect of procyanidolic oligomers on the permeability of the blood-brain barrier
    • A.M. Robert, J.M. Tixier, L. Robert, J.M. Legeais, and G. Renard Effect of procyanidolic oligomers on the permeability of the blood-brain barrier Pathol. Biol. 49 2001 298 304
    • (2001) Pathol. Biol. , vol.49 , pp. 298-304
    • Robert, A.M.1    Tixier, J.M.2    Robert, L.3    Legeais4    Renard, G.J.M.5
  • 42
    • 0028117768 scopus 로고
    • Role of flavonoids and iron chelation in antioxidant action
    • I. Morel, G. Lescoat, P. Cillard, and J. Cillard Role of flavonoids and iron chelation in antioxidant action Methods Enzymol. 234 1994 437 443
    • (1994) Methods Enzymol. , vol.234 , pp. 437-443
    • Morel, I.1    Lescoat, G.2    Cillard3    Cillard, J.P.4
  • 45
    • 0038637961 scopus 로고    scopus 로고
    • Selenium, copper, and zinc concentrations in intestinal cancer tissue and in colon and rectum polyps
    • M. Kucharzewski, J. Braziewicz, U. Majewska, and S. Gozdz Selenium, copper, and zinc concentrations in intestinal cancer tissue and in colon and rectum polyps Biol. Trace Elem. Res. 92 2003 1 10
    • (2003) Biol. Trace Elem. Res. , vol.92 , pp. 1-10
    • Kucharzewski, M.1    Braziewicz, J.2    Majewska3    Gozdz, S.U.4
  • 46
    • 0028954133 scopus 로고
    • X-ray fluorescence in the assessment of inter-elemental interactions in rat liver following lead treatment
    • D. Dhawan, B. Singh, B. Chand, N. Singh, P.C. Mangal, and P.N. Trehan X-ray fluorescence in the assessment of inter-elemental interactions in rat liver following lead treatment Biometals 8 1995 105 110
    • (1995) Biometals , vol.8 , pp. 105-110
    • Dhawan, D.1    Singh, B.2    Chand, B.3    Singh, N.4    Mangal5    Trehan, P.N.P.C.6
  • 47
    • 0037355725 scopus 로고    scopus 로고
    • Copper exposure modifies the content and distribution of trace metals in mammalian cultured cells
    • L. Tapia, M. Suazo, C. Hodar, V. Cambiazo, and M. Gonzalez Copper exposure modifies the content and distribution of trace metals in mammalian cultured cells Biometals 16 2003 169 174
    • (2003) Biometals , vol.16 , pp. 169-174
    • Tapia, L.1    Suazo, M.2    Hodar, C.3    Cambiazo4    Gonzalez, M.V.5
  • 48
    • 4243728502 scopus 로고
    • Micellar colorimetric determination of dithizon metal chelates
    • P. Rajesh, and R.R. Paradlkar Micellar colorimetric determination of dithizon metal chelates Anal. Chem. 66 1994 2752
    • (1994) Anal. Chem. , vol.66 , pp. 2752
    • Rajesh1    Paradlkar, R.R.P.2
  • 49
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • H. Ohkawa, N. Ohishi, and K. Yagi Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal. Biochem. 95 1979 351 358
    • (1979) Anal. Biochem. , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi2    Yagi, K.N.3
  • 50
    • 0017064979 scopus 로고
    • A fluorometric method for determination of oxidized and reduced glutathione in tissues
    • P.J. Hissin, and R. Hilf A fluorometric method for determination of oxidized and reduced glutathione in tissues Anal. Biochem. 74 1976 214 226
    • (1976) Anal. Biochem. , vol.74 , pp. 214-226
    • Hissin1    Hilf, R.P.J.2
  • 52
    • 0036006635 scopus 로고    scopus 로고
    • Antioxidant activities of pomegranate fruit extract and its anthocyanidins: Delphinidin, cyanidin, and pelargonidin
    • Y. Noda, T. Kaneyuki, A. Mori, and L. Packer Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin J. Agric. Food Chem. 50 2002 166 177
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 166-177
    • Noda, Y.1    Kaneyuki, T.2    Mori3    Packer, L.A.4
  • 53
    • 0034733904 scopus 로고    scopus 로고
    • Effects of lead on long-term potentiation in hippocampal CA3 vary with age
    • R.J. Hussain, P.J. Parsons, and D.O. Carpenter Effects of lead on long-term potentiation in hippocampal CA3 vary with age Dev. Brain Res. 121 2000 243 252
    • (2000) Dev. Brain Res. , vol.121 , pp. 243-252
    • Hussain, R.J.1    Parsons2    Carpenter, D.O.P.J.3
  • 54
    • 0032079242 scopus 로고    scopus 로고
    • Synaptic plasticity in the CA1 and CA3 hippocampal region of pre- and postnatally lead-exposed rats
    • M. Gutowski, L. Altmann, K. Sveinsson, and H. Wiegand Synaptic plasticity in the CA1 and CA3 hippocampal region of pre- and postnatally lead-exposed rats Toxicol. Lett. 95 1998 195 203
    • (1998) Toxicol. Lett. , vol.95 , pp. 195-203
    • Gutowski, M.1    Altmann, L.2    Sveinsson3    Wiegand, H.K.4
  • 57
    • 0026454763 scopus 로고
    • Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene
    • I. Garcia, Y. Martinou, and J.C. Martinou Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene Science 258 1992 302 304
    • (1992) Science , vol.258 , pp. 302-304
    • Garcia, I.1    Martinou2    Martinou, J.C.Y.3
  • 59
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Z. Oltvai, C. Milliman, and S.J. Korsmeyer Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death Cell 74 1993 609 619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.1    Milliman2    Korsmeyer, S.J.C.3
  • 60
    • 0029670976 scopus 로고    scopus 로고
    • 1,10-Phenanthroline stimulates internucleosomal DNA fragmentation in isolated rat-liver nuclei by promoting the redox activity of endogenous copper ions
    • M.J. Burkitt, L. Milne, P. Nicotera, and S. Orrenius 1,10-Phenanthroline stimulates internucleosomal DNA fragmentation in isolated rat-liver nuclei by promoting the redox activity of endogenous copper ions Biochem. J. 313 1996 163 169
    • (1996) Biochem. J. , vol.313 , pp. 163-169
    • Burkitt, M.J.1    Milne, L.2    Nicotera3    Orrenius, S.P.4
  • 61
    • 0030004287 scopus 로고    scopus 로고
    • Manganese and 1-methyl-4-(2′-ethylphenyl)-1,2,3,6- tetrahydropyridine induce apoptosis in PC12 cells
    • M.S. Desole, L. Sciola, M.R. Delogu, S. Sircana, and R. Migheli Manganese and 1-methyl-4-(2′-ethylphenyl)-1,2,3,6-tetrahydropyridine induce apoptosis in PC12 cells Neurosci. Lett. 209 1996 193 296
    • (1996) Neurosci. Lett. , vol.209 , pp. 193-296
    • Desole, M.S.1    Sciola, L.2    Delogu, M.R.3    Sircana4    Migheli, R.S.5
  • 62
    • 0032411886 scopus 로고    scopus 로고
    • Mercuric chloride induces apoptosis in human T lymphocytes: Evidence of mitochondrial dysfunction
    • T.L. Guo, M.A. Miller, I.M. Shapiro, and B.J. Shenker Mercuric chloride induces apoptosis in human T lymphocytes: evidence of mitochondrial dysfunction Toxicol. Appl. Pharmacol. 153 1998 250 257
    • (1998) Toxicol. Appl. Pharmacol. , vol.153 , pp. 250-257
    • Guo, T.L.1    Miller, M.A.2    Shapiro3    Shenker, B.J.I.M.4
  • 64
    • 0344430160 scopus 로고    scopus 로고
    • Hydrogen peroxide induces apoptosis in cerebral vascular smooth muscle cells: Possible relation to neurodegenerative diseases and strokes
    • J.F. Li, W.Y. Li, J.L. Su, W.M. Liu, T.A. Bella, and M.A. Burton Hydrogen peroxide induces apoptosis in cerebral vascular smooth muscle cells: possible relation to neurodegenerative diseases and strokes Brain Res. Bull. 62 2003 101 106
    • (2003) Brain Res. Bull. , vol.62 , pp. 101-106
    • Li, J.F.1    Li, W.Y.2    Su, J.L.3    Liu, W.M.4    Bella5    Burton, M.A.T.A.6
  • 65
    • 1942519734 scopus 로고    scopus 로고
    • Hydrogen peroxide induced apoptosis in amnion-derived WISH cells is not inhibited by vitamin C
    • D. Kumar, D.W. Lundgren, R.M. Moore, R.J. Silver, and J.J. Moore Hydrogen peroxide induced apoptosis in amnion-derived WISH cells is not inhibited by vitamin C Placenta 25 2004 266 272
    • (2004) Placenta , vol.25 , pp. 266-272
    • Kumar, D.1    Lundgren, D.W.2    Moore, R.M.3    Silver4    Moore, J.J.R.J.5
  • 66
    • 0029873387 scopus 로고    scopus 로고
    • Reactive oxygen species and programmed cell death
    • M.D. Jacobson Reactive oxygen species and programmed cell death Trends Biochem. Sci. 21 1996 83 86
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 83-86
    • Jacobson, M.D.1
  • 67
    • 0030744048 scopus 로고    scopus 로고
    • Bcl-xL overexpression attenuates glutathione depletion in FL5.12 cells following interleukin-3 withdrawal
    • H.K. Bojes, K. Datta, J. Xu, A. Chin, P. Simonian, G. Nun, and J.P. Kehrer Bcl-xL overexpression attenuates glutathione depletion in FL5.12 cells following interleukin-3 withdrawal Biochem. J. 325 1997 315 319
    • (1997) Biochem. J. , vol.325 , pp. 315-319
    • Bojes, H.K.1    Datta, K.2    Xu, J.3    Chin, A.4    Simonian, P.5    Nun6    Kehrer, J.P.G.7
  • 68
    • 0032571565 scopus 로고    scopus 로고
    • Rapid and specific reactive oxygen species generation via NADPH oxidase activation during Fas-mediated apoptosis
    • Y. Suzuki, Y. Ono, and Y. Hirabayashi Rapid and specific reactive oxygen species generation via NADPH oxidase activation during Fas-mediated apoptosis FEBS Lett. 425 1998 209 212
    • (1998) FEBS Lett. , vol.425 , pp. 209-212
    • Suzuki, Y.1    Ono2    Hirabayashi, Y.Y.3
  • 69
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • T.M. Buttke, and P.A. Sandstrom Oxidative stress as a mediator of apoptosis Immunol. Today 15 1994 7 10
    • (1994) Immunol. Today , vol.15 , pp. 7-10
    • Buttke1    Sandstrom, P.A.T.M.2
  • 70
    • 0026048747 scopus 로고
    • Succimer, an oral lead chelator
    • K.V. Mann, and J.D. Tavers Succimer, an oral lead chelator Clin. Pharm. 10 1991 914 922
    • (1991) Clin. Pharm. , vol.10 , pp. 914-922
    • Mann1    Tavers, J.D.K.V.2
  • 71
    • 0033572831 scopus 로고    scopus 로고
    • Efficacy of succimer chelation for reducing brain lead in a primate model of human lead exposure
    • J.D. Cremin, M.L. Luck, N.K. Laughlin, and D.R. Smith Efficacy of succimer chelation for reducing brain lead in a primate model of human lead exposure Toxicol. Appl. Pharmacol. 161 1999 283 293
    • (1999) Toxicol. Appl. Pharmacol. , vol.161 , pp. 283-293
    • Cremin, J.D.1    Luck, M.L.2    Laughlin3    Smith, D.R.N.K.4
  • 72
    • 0344142393 scopus 로고    scopus 로고
    • Effects of some sulfur-containing antioxidants on lead-exposed lenses
    • R. Neal, K. Cooper, G. Kellogg, H. Gurer, and N. Ercal Effects of some sulfur-containing antioxidants on lead-exposed lenses Free Radic. Biol. Med. 26 1999 239 243
    • (1999) Free Radic. Biol. Med. , vol.26 , pp. 239-243
    • Neal, R.1    Cooper, K.2    Kellogg, G.3    Gurer4    Ercal, N.H.5
  • 73
    • 0037102716 scopus 로고    scopus 로고
    • Lead induced oxidative damage and its response to combined administration of α-lipoic acid and succimers in rats
    • P. Manisha, and S.J.S. Flora Lead induced oxidative damage and its response to combined administration of α-lipoic acid and succimers in rats Toxicology 177 2002 187 196
    • (2002) Toxicology , vol.177 , pp. 187-196
    • Manisha1    Flora, S.J.S.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.