Chimeric β-Lactamases: Global Conservation of Parental Function and Fast Time-Scale Dynamics with Increased Slow Motions

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Clouthier, Christopher M ^a,b   Morin, Sébastien ^a   Gobeil, Sophie M C ^a,b   Doucet, Nicolas ^a   Blanchet, Jonathan ^a,b   Nguyen, Elisabeth ^a,b   Gagné, Stéphane M ^a   Pelletier, Joelle N ^a,b  

^a UNIVERSITÉ LAVAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; BETA LACTAMASE PSE 4; BETA LACTAMASE TEM 1; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CHEMICAL PARAMETERS; CHIMERA; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; ENZYME ENGINEERING; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; FAST TIME SCALE DYNAMICS; FLUOROMETRY; GENETIC RECOMBINATION; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTON NUCLEAR MAGNETIC RESONANCE; SLOW TIME SCALE MOTION; STRUCTURE ACTIVITY RELATION; THERMAL SCANNING FLUORIMETRY;

BETA-LACTAMASES; CIRCULAR DICHROISM; FLUOROMETRY; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN STRUCTURE, SECONDARY;

BACTERIA (MICROORGANISMS);

EID: 84871353831     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052283     Document Type: Article

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