Inhibitory effect of ethanol extract of magnolia officinalis on memory impairment and amyloidogenesis in a transgenic mouse model of Alzheimer's disease via regulating β-secretase activity

Phytotherapy Research

Volumn 26, Issue 12, 2012, Pages 1884-1892

  Lee, Young Jung ^a   Choi, Dong Young ^a   Han, Sang Bae ^a   Kim, Young Hee ^b   Kim, Ki Ho ^b   Hwang, Bang Yeon ^a   Kang, Jong Koo ^a   Lee, Beom Jun ^a   Oh, Ki Won ^a   Hong, Jin Tae ^a  

^a Chungbuk National University   (South Korea)

^b Bioland Ltd   (South Korea)

Author keywords

secretase; Alzheimer's disease; amyloid beta; Magnolia

Indexed keywords

4 O METHYLHONOKIOL; ALCOHOL; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SECRETASE 1; HONOKIOL; MAGNOLIA OFFICINALIS EXTRACT; MAGNOLOL; PROTEIN C99; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMYLOIDOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BARK; CONTROLLED STUDY; DISEASE CONTROL; DOWN REGULATION; DRUG EFFICACY; DRUG INHIBITION; ENZYME ACTIVITY; ENZYME REGULATION; IN VIVO STUDY; LATENT PERIOD; MAZE TEST; MEMORY DISORDER; MOUSE; NEUROPROTECTION; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN SYNTHESIS; TRANSGENIC MOUSE; TREATMENT DURATION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ETHANOL; MAGNOLIA; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PLANT BARK; PLANT EXTRACTS;

MAGNOLIA; MAGNOLIA OFFICINALIS; MUS; MUS MUSCULUS;

EID: 84871281482     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4643     Document Type: Article

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