A neutrophil elastase inhibitor prevents bleomycin-induced pulmonary fibrosis in mice

European Respiratory Journal

Volumn 40, Issue 6, 2012, Pages 1475-1482

  Takemasa, Akihiro ^a   Ishii, Yoshiki ^a   Fukuda, Takeshi ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Early stage pulmonary fibrosis; Neutrophil elastase; Sivelestat; Transforming growth factor 1

Indexed keywords

BLEOMYCIN; COLLAGEN; LEUKOCYTE ELASTASE; LEUKOCYTE ELASTASE INHIBITOR; MESSENGER RNA; PHOSPHOPROTEIN; SIVELESTAT; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; GENE EXPRESSION; LUNG FIBROSIS; LUNG LAVAGE; LYMPHOCYTE; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; TRANSFORMING GROWTH FACTOR BETA1 GENE;

ANIMALS; BLEOMYCIN; BRONCHOALVEOLAR LAVAGE; COLLAGEN; FIBROSIS; GLYCINE; INFLAMMATION; LEUKOCYTE ELASTASE; LUNG; MALE; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PULMONARY FIBROSIS; SERINE PROTEINASE INHIBITORS; SMAD2 PROTEIN; SULFONAMIDES; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84871228345     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00127011     Document Type: Article

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