메뉴 건너뛰기




Volumn 18, Issue 6, 2012, Pages 485-491

Inherited pancreatic cancer syndromes

Author keywords

APC; ATM; BRCA1; BRCA2; CDKN2A; Familial pancreatic cancer; genetic counseling; genetics; MLH1; MSH2; MSH6; PALB2; PMS2; PRSS1; risk reduction therapy and medical management of pancreatic cancer risk; STK11

Indexed keywords

APC PROTEIN; ATM PROTEIN; BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; BRCA2 PROTEIN; MISMATCH REPAIR PROTEIN PMS2; PROTEIN; PROTEIN SERINE THREONINE KINASE; PRSS1 PROTEIN; UNCLASSIFIED DRUG;

EID: 84871211933     PISSN: 15289117     EISSN: 1540336X     Source Type: Journal    
DOI: 10.1097/PPO.0b013e318278c4a6     Document Type: Review
Times cited : (89)

References (70)
  • 1
    • 67349238762 scopus 로고    scopus 로고
    • Pancreatic cancer surveillance among high-risk populations: Knowledge and intent
    • Lewis ZK, Frost CJ, Venne VL. Pancreatic cancer surveillance among high-risk populations: knowledge and intent. J Genet Couns. 2009;18: 229-238.
    • (2009) J Genet Couns. , vol.18 , pp. 229-238
    • Lewis, Z.K.1    Frost, C.J.2    Venne, V.L.3
  • 3
    • 34948870763 scopus 로고    scopus 로고
    • Advances in counselling and surveillance of patients at risk for pancreatic cancer
    • Brand RE, Lerch MM, Rubinstein WS, et al. Advances in counselling and surveillance of patients at risk for pancreatic cancer. Gut. 2007; 56:1460-1469.
    • (2007) Gut. , vol.56 , pp. 1460-1469
    • Brand, R.E.1    Lerch, M.M.2    Rubinstein, W.S.3
  • 4
    • 0036668721 scopus 로고    scopus 로고
    • Evidence for a major geneinfluencing risk of pancreatic cancer
    • Klein AP, Beaty TH, Bailey-Wilson JE, et al. Evidence for a major geneinfluencing risk of pancreatic cancer. Genet Epidemiol. 2002;23: 133-149.
    • (2002) Genet Epidemiol. , vol.23 , pp. 133-149
    • Klein, A.P.1    Beaty, T.H.2    Bailey-Wilson, J.E.3
  • 5
    • 0032528265 scopus 로고    scopus 로고
    • The concise handbook of family cancer syndromes. Mayo Familial Cancer Program
    • Lindor NM, Greene MH. The concise handbook of family cancer syndromes. Mayo Familial Cancer Program. J Natl Cancer Inst. 1998;90: 1039-1071.
    • (1998) J Natl Cancer Inst. , vol.90 , pp. 1039-1071
    • Lindor, N.M.1    Greene, M.H.2
  • 6
    • 75149143956 scopus 로고    scopus 로고
    • Importance of age of onset in pancreatic cancer kindreds
    • Brune KA, Lau B, Palmisano E, et al. Importance of age of onset in pancreatic cancer kindreds. J Natl Cancer Inst. 2010;102:119-126.
    • (2010) J Natl Cancer Inst. , vol.102 , pp. 119-126
    • Brune, K.A.1    Lau, B.2    Palmisano, E.3
  • 7
    • 69249129141 scopus 로고    scopus 로고
    • Pancreatic cancer patients who smoke and drink are diagnosed at younger ages
    • Brand RE, Greer JB, Zolotarevsky E, et al. Pancreatic cancer patients who smoke and drink are diagnosed at younger ages. Clin Gastroen-terol Hepatol. 2009;7:1007-1012.
    • (2009) Clin Gastroen-terol Hepatol. , vol.7 , pp. 1007-1012
    • Brand, R.E.1    Greer, J.B.2    Zolotarevsky, E.3
  • 8
    • 84859393143 scopus 로고    scopus 로고
    • Frequent detection of pancreatic lesions in asymptomatic high-risk individuals
    • quiz e714-e795
    • Canto MI, Hruban RH, Fishman EK, et al. Frequent detection of pancreatic lesions in asymptomatic high-risk individuals. Gastroenterol. 2012;142:796-804; quiz e714-e795.
    • (2012) Gastroenterol. , vol.142 , pp. 796-804
    • Canto, M.I.1    Hruban, R.H.2    Fishman, E.K.3
  • 9
    • 34248170114 scopus 로고    scopus 로고
    • Meta-analysis of BRCA1 and BRCA2 pene-trance
    • Chen S, Parmigiani G. Meta-analysis of BRCA1 and BRCA2 pene-trance. J Clin Oncol. 2007;25:1329-1333.
    • (2007) J Clin Oncol. , vol.25 , pp. 1329-1333
    • Chen, S.1    Parmigiani, G.2
  • 10
    • 0029955159 scopus 로고    scopus 로고
    • The genetic attributable risk of breast and ovarian cancer
    • Claus EB, Schildkraut JM, Thompson WD, et al. The genetic attributable risk of breast and ovarian cancer. Cancer. 1996;77:2318-2324.
    • (1996) Cancer. , vol.77 , pp. 2318-2324
    • Claus, E.B.1    Schildkraut, J.M.2    Thompson, W.D.3
  • 11
    • 29144509766 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases
    • Pal T, Permuth-Wey J, Betts JA, et al. BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases. Cancer. 2005;104:2807-2816.
    • (2005) Cancer. , vol.104 , pp. 2807-2816
    • Pal, T.1    Permuth-Wey, J.2    Betts, J.A.3
  • 12
    • 0035098503 scopus 로고    scopus 로고
    • Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer
    • Risch HA, McLaughlin JR, Cole DE, et al. Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. Am J Hum Genet. 2001;68:700-710.
    • (2001) Am J Hum Genet. , vol.68 , pp. 700-710
    • Risch, H.A.1    McLaughlin, J.R.2    Cole, D.E.3
  • 13
    • 0030910022 scopus 로고    scopus 로고
    • The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews
    • Struewing JP, Hartge P, Wacholder S, et al. The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. N Engl J Med. 1997;336:1401-1408.
    • (1997) N Engl J Med. , vol.336 , pp. 1401-1408
    • Struewing, J.P.1    Hartge, P.2    Wacholder, S.3
  • 14
    • 0037130889 scopus 로고    scopus 로고
    • Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program
    • Brose MS, Rebbeck TR, Calzone KA, et al. Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program. J Natl Cancer Inst. 2002;94:1365-1372.
    • (2002) J Natl Cancer Inst. , vol.94 , pp. 1365-1372
    • Brose, M.S.1    Rebbeck, T.R.2    Calzone, K.A.3
  • 15
    • 2542590280 scopus 로고    scopus 로고
    • Down-regulation of BRCA1 in chronic pancreatitis and sporadic pancreatic adenocarcinoma
    • Beger C, Ramadani M, Meyer S, et al. Down-regulation of BRCA1 in chronic pancreatitis and sporadic pancreatic adenocarcinoma. Clin Cancer Res. 2004;10:3780-3787.
    • (2004) Clin Cancer Res. , vol.10 , pp. 3780-3787
    • Beger, C.1    Ramadani, M.2    Meyer, S.3
  • 16
    • 84864360055 scopus 로고    scopus 로고
    • Risk of cancer other than breast or ovarian in individuals with BRCA1 and BRCA2 mutations
    • Moran A, O'Hara C, Khan S, et al. Risk of cancer other than breast or ovarian in individuals with BRCA1 and BRCA2 mutations. Fam Cancer. 2012;11:235-242.
    • (2012) Fam Cancer. , vol.11 , pp. 235-242
    • Moran, A.1    O'Hara, C.2    Khan, S.3
  • 17
    • 58749112549 scopus 로고    scopus 로고
    • Absence of germline BR-CA1 mutations in familial pancreatic cancer patients
    • Axilbund JE, Argani P, Kamiyama M, et al. Absence of germline BR-CA1 mutations in familial pancreatic cancer patients. Cancer Biol Ther. 2009;8:131-135.
    • (2009) Cancer Biol Ther. , vol.8 , pp. 131-135
    • Axilbund, J.E.1    Argani, P.2    Kamiyama, M.3
  • 18
    • 0006713602 scopus 로고
    • Identification of the breast cancer susceptibility gene BRCA2
    • Wooster R, Bignell G, Lancaster J, et al. Identification of the breast cancer susceptibility gene BRCA2. Nature. 1995;378:789-792.
    • (1995) Nature. , vol.378 , pp. 789-792
    • Wooster, R.1    Bignell, G.2    Lancaster, J.3
  • 19
    • 0030933762 scopus 로고    scopus 로고
    • Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2
    • Sharan SK, Morimatsu M, Albrecht U, et al. Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2. Nature. 1997;386:804-810.
    • (1997) Nature. , vol.386 , pp. 804-810
    • Sharan, S.K.1    Morimatsu, M.2    Albrecht, U.3
  • 20
    • 12644253827 scopus 로고    scopus 로고
    • Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas
    • Goggins M, Schutte M, Lu J, et al. Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas. Cancer Res. 1996;56:5360-5364.
    • (1996) Cancer Res. , vol.56 , pp. 5360-5364
    • Goggins, M.1    Schutte, M.2    Lu, J.3
  • 21
    • 0036644884 scopus 로고    scopus 로고
    • Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: Deleterious BRCA2 mutations in 17%
    • Murphy KM, Brune KA, Griffin C, et al. Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%. Cancer Res. 2002;62: 3789-3793.
    • (2002) Cancer Res. , vol.62 , pp. 3789-3793
    • Murphy, K.M.1    Brune, K.A.2    Griffin, C.3
  • 22
    • 0033523268 scopus 로고    scopus 로고
    • Cancer risks in BRCA2 mutation carriers
    • The Breast Cancer Linkage Consortium
    • The Breast Cancer Linkage Consortium. Cancer risks in BRCA2 mutation carriers. J Natl Cancer Inst. 1999;91:1310-1316.
    • (1999) J Natl Cancer Inst. , vol.91 , pp. 1310-1316
  • 23
    • 17244375049 scopus 로고    scopus 로고
    • Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
    • Bryant HE, Schultz N, Thomas HD, et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature. 2005;434:913-917.
    • (2005) Nature. , vol.434 , pp. 913-917
    • Bryant, H.E.1    Schultz, N.2    Thomas, H.D.3
  • 24
    • 79956068235 scopus 로고    scopus 로고
    • Evidence for the efficacy of Iniparib, a PARP-1 inhibitor, in BRCA2-associated pancreatic cancer
    • Fogelman DR, Wolff RA, Kopetz S, et al. Evidence for the efficacy of Iniparib, a PARP-1 inhibitor, in BRCA2-associated pancreatic cancer. Anticancer Res. 2011;31:1417-1420.
    • (2011) Anticancer Res. , vol.31 , pp. 1417-1420
    • Fogelman, D.R.1    Wolff, R.A.2    Kopetz, S.3
  • 25
    • 79957828268 scopus 로고    scopus 로고
    • Inactivation of Brca2 cooperates with Trp53(R172H) to induce invasive pancreatic ductal adeno-carcinomas in mice: A mouse model of familial pancreatic cancer
    • Feldmann G, Karikari C, dal Molin M, et al. Inactivation of Brca2 cooperates with Trp53(R172H) to induce invasive pancreatic ductal adeno-carcinomas in mice: a mouse model of familial pancreatic cancer. Cancer Biol Ther. 2011;11:959-968.
    • (2011) Cancer Biol Ther. , vol.11 , pp. 959-968
    • Feldmann, G.1    Karikari, C.2    Dal Molin, M.3
  • 26
    • 33846625493 scopus 로고    scopus 로고
    • PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene
    • Rahman N, Seal S, Thompson D, et al. PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene. Nat Genet. 2007;39:165-167.
    • (2007) Nat Genet. , vol.39 , pp. 165-167
    • Rahman, N.1    Seal, S.2    Thompson, D.3
  • 27
    • 64849092309 scopus 로고    scopus 로고
    • Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene
    • Jones S, Hruban RH, Kamiyama M, et al. Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. Science. 2009; 324:217.
    • (2009) Science , vol.324 , pp. 217
    • Jones, S.1    Hruban, R.H.2    Kamiyama, M.3
  • 28
    • 79952741549 scopus 로고    scopus 로고
    • Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer
    • Casadei S, Norquist BM, Walsh T, et al. Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer. Cancer Res. 2011;71:2222-2229.
    • (2011) Cancer Res. , vol.71 , pp. 2222-2229
    • Casadei, S.1    Norquist, B.M.2    Walsh, T.3
  • 29
    • 0035879874 scopus 로고    scopus 로고
    • Cancer risk in heterozygotes for ataxia-telangiectasia
    • Geoffroy-Perez B, Janin N, Ossian K, et al. Cancer risk in heterozygotes for ataxia-telangiectasia. Int J Cancer. 2001;93:288-293.
    • (2001) Int J Cancer. , vol.93 , pp. 288-293
    • Geoffroy-Perez, B.1    Janin, N.2    Ossian, K.3
  • 30
    • 65549085146 scopus 로고    scopus 로고
    • Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells
    • Sahu RP, Batra S, Srivastava SK. Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells. Br J Cancer. 2009;100:1425-1433.
    • (2009) Br J Cancer. , vol.100 , pp. 1425-1433
    • Sahu, R.P.1    Batra, S.2    Srivastava, S.K.3
  • 31
    • 84863830403 scopus 로고    scopus 로고
    • ATM mutations in patients with hereditary pancreatic cancer
    • Roberts NJ, Jiao Y, Yu J, et al. ATM mutations in patients with hereditary pancreatic cancer. Cancer Disc. 2012;2:41-46.
    • (2012) Cancer Disc. , vol.2 , pp. 41-46
    • Roberts, N.J.1    Jiao, Y.2    Yu, J.3
  • 32
    • 0343059561 scopus 로고
    • Ataxia-telangiectasia
    • Pagon RA, Bird TD, Dolan CR, et al, eds updated 2010 Mar11
    • Gatti R. Ataxia-telangiectasia. In: Pagon RA, Bird TD, Dolan CR, et al, eds. Gene Rev. 1993; updated 2010 Mar11.
    • (1993) Gene Rev.
    • Gatti, R.1
  • 33
    • 84862777152 scopus 로고    scopus 로고
    • Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia
    • e739
    • Kanda M, Matthaei H, Wu J, et al. Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia. Gastroenterology. 2012;142:730-733, e739.
    • (2012) Gastroenterology. , vol.142 , pp. 730-733
    • Kanda, M.1    Matthaei, H.2    Wu, J.3
  • 34
    • 0033836334 scopus 로고    scopus 로고
    • Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden)
    • Vasen HF, Gruis NA, Frants RR, et al. Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden). Int J Cancer. 2000;87:809-811.
    • (2000) Int J Cancer. , vol.87 , pp. 809-811
    • Vasen, H.F.1    Gruis, N.A.2    Frants, R.R.3
  • 35
    • 79952742260 scopus 로고    scopus 로고
    • Prevalence of CDKN2A mutations in pancreatic cancer patients: Implications for genetic counseling
    • McWilliams RR, Wieben ED, Rabe KG, et al. Prevalence of CDKN2A mutations in pancreatic cancer patients: implications for genetic counseling. Eur J Hum Genet. 2011;19:472-478.
    • (2011) Eur J Hum Genet. , vol.19 , pp. 472-478
    • McWilliams, R.R.1    Wieben, E.D.2    Rabe, K.G.3
  • 36
    • 0025832546 scopus 로고
    • Screening guidelines and premor-bid diagnosis of familial adenomatous polyposis using linkage
    • Petersen GM, Slack J, Nakamura Y. Screening guidelines and premor-bid diagnosis of familial adenomatous polyposis using linkage. Gastro-enterology. 1991;100:1658-1664.
    • (1991) Gastro-enterology. , vol.100 , pp. 1658-1664
    • Petersen, G.M.1    Slack, J.2    Nakamura, Y.3
  • 37
    • 0035052054 scopus 로고    scopus 로고
    • Duodenal adenomatosis in familial adenomatous polyposis coli: A review of the literature and results from the Heidelberg Polyposis Register
    • Kadmon M, Tandara A, Herfarth C. Duodenal adenomatosis in familial adenomatous polyposis coli: a review of the literature and results from the Heidelberg Polyposis Register. Int J Colorectal Dis. 2001;16:63-75.
    • (2001) Int J Colorectal Dis. , vol.16 , pp. 63-75
    • Kadmon, M.1    Tandara, A.2    Herfarth, C.3
  • 38
    • 0034955851 scopus 로고    scopus 로고
    • AGA technical review on hereditary colorectal cancer and genetic testing
    • Giardiello FM, Brensinger JD, Petersen GM. AGA technical review on hereditary colorectal cancer and genetic testing. Gastroenterology. 2001;121:198-213.
    • (2001) Gastroenterology. , vol.121 , pp. 198-213
    • Giardiello, F.M.1    Brensinger, J.D.2    Petersen, G.M.3
  • 39
    • 58849130663 scopus 로고    scopus 로고
    • Cumulative lifetime incidence of extracolonic cancers in Lynch syndrome: A report of 121 families with proven mutations
    • Barrow E, Robinson L, Alduaij W, et al. Cumulative lifetime incidence of extracolonic cancers in Lynch syndrome: a report of 121 families with proven mutations. Clin Genet. 2009;75:141-149.
    • (2009) Clin Genet. , vol.75 , pp. 141-149
    • Barrow, E.1    Robinson, L.2    Alduaij, W.3
  • 40
    • 70350733425 scopus 로고    scopus 로고
    • Risk of pancreatic cancer in families with Lynch syndrome
    • Kastrinos F, Mukherjee B, Tayob N, et al. Risk of pancreatic cancer in families with Lynch syndrome. JAMA. 2009;302:1790-1795.
    • (2009) JAMA , vol.302 , pp. 1790-1795
    • Kastrinos, F.1    Mukherjee, B.2    Tayob, N.3
  • 41
    • 45749151120 scopus 로고    scopus 로고
    • Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC)
    • Geary J, Sasieni P, Houlston R, et al. Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC). Fam Cancer. 2008;7:163-172.
    • (2008) Fam Cancer. , vol.7 , pp. 163-172
    • Geary, J.1    Sasieni, P.2    Houlston, R.3
  • 42
    • 10144246566 scopus 로고    scopus 로고
    • Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene
    • Whitcomb DC, Gorry MC, Preston RA, et al. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet. 1996;14:141-145.
    • (1996) Nat Genet. , vol.14 , pp. 141-145
    • Whitcomb, D.C.1    Gorry, M.C.2    Preston, R.A.3
  • 43
    • 0035080006 scopus 로고    scopus 로고
    • Expression and penetrance of the hereditary pancreatitis phenotype in monozygotic twins
    • Amann ST, Gates LK, Aston CE, et al. Expression and penetrance of the hereditary pancreatitis phenotype in monozygotic twins. Gut. 2001;48:542-547.
    • (2001) Gut. , vol.48 , pp. 542-547
    • Amann, S.T.1    Gates, L.K.2    Aston, C.E.3
  • 46
    • 0034940538 scopus 로고    scopus 로고
    • Cigarette smoking as a risk factor for pancreatic cancer in patients with hereditary pancreatitis
    • Lowenfels AB, Maisonneuve P, Whitcomb DC, et al. Cigarette smoking as a risk factor for pancreatic cancer in patients with hereditary pancreatitis. JAMA. 2001;286:169-170.
    • (2001) JAMA , vol.286 , pp. 169-170
    • Lowenfels, A.B.1    Maisonneuve, P.2    Whitcomb, D.C.3
  • 47
    • 69949152231 scopus 로고    scopus 로고
    • Mortality rate and risk factors in patients with hereditary pancreatitis: Uni-and multidimensional analyses
    • Rebours V, Boutron-Ruault MC, Jooste V, et al. Mortality rate and risk factors in patients with hereditary pancreatitis: uni-and multidimensional analyses. Dig Liver Dis. 2009;104:2312-2317.
    • (2009) Dig Liver Dis. , vol.104 , pp. 2312-2317
    • Rebours, V.1    Boutron-Ruault, M.C.2    Jooste, V.3
  • 48
    • 84856088337 scopus 로고    scopus 로고
    • EMT and dissemination precede pancreatic tumor formation
    • Rhim AD, Mirek ET, Aiello NM, et al. EMT and dissemination precede pancreatic tumor formation. Cell. 2012;148:349-361.
    • (2012) Cell. , vol.148 , pp. 349-361
    • Rhim, A.D.1    Mirek, E.T.2    Aiello, N.M.3
  • 49
    • 84859710888 scopus 로고    scopus 로고
    • An NF-kappaB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice
    • Daniluk J, Liu Y, Deng D, et al. An NF-kappaB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice. J Clin Invest. 2012;122:1519-1528.
    • (2012) J Clin Invest. , vol.122 , pp. 1519-1528
    • Daniluk, J.1    Liu, Y.2    Deng, D.3
  • 50
    • 0035553209 scopus 로고    scopus 로고
    • Pancreatic cancer in hereditary pancreatitisYconsensus guidelines for prevention, screening, and treatment
    • Ulrich CD II. Pancreatic cancer in hereditary pancreatitisYconsensus guidelines for prevention, screening, and treatment. Pancreatology. 2001;1:416-422.
    • (2001) Pancreatology. , vol.1 , pp. 416-422
    • Ulrich, C.D.I.I.1
  • 51
    • 77956637036 scopus 로고    scopus 로고
    • Total pancreatectomy and islet cell autotransplantation as a means of treating patients with genetically linked pancreatitis
    • discussion 685-676
    • Sutton JM, Schmulewitz N, Sussman JJ, et al. Total pancreatectomy and islet cell autotransplantation as a means of treating patients with genetically linked pancreatitis. Surgery. 2010;148:676-685; discussion 685-676.
    • (2010) Surgery. , vol.148 , pp. 676-685
    • Sutton, J.M.1    Schmulewitz, N.2    Sussman, J.J.3
  • 52
  • 53
    • 78650223070 scopus 로고    scopus 로고
    • Pancreatic cancer risk counselling and screening: Impact on perceived risk and psychological functioning
    • Maheu C, Vodermaier A, Rothenmund H, et al. Pancreatic cancer risk counselling and screening: impact on perceived risk and psychological functioning. Familial Cancer. 2010;9:617-624.
    • (2010) Familial Cancer. , vol.9 , pp. 617-624
    • Maheu, C.1    Vodermaier, A.2    Rothenmund, H.3
  • 54
    • 11144353646 scopus 로고    scopus 로고
    • Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds
    • Klein AP, Brune KA, Petersen GM, et al. Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds. Cancer Res. 2004;64: 2634-2638.
    • (2004) Cancer Res. , vol.64 , pp. 2634-2638
    • Klein, A.P.1    Brune, K.A.2    Petersen, G.M.3
  • 55
    • 84858293392 scopus 로고    scopus 로고
    • Contribution of germline mutations in the BRCA and PALB2 genes to pancreatic cancer in Italy
    • Ghiorzo P, Pensotti V, Fornarini G, et al. Contribution of germline mutations in the BRCA and PALB2 genes to pancreatic cancer in Italy. Fa-milial Cancer. 2012;11:41-47.
    • (2012) Fa-milial Cancer. , vol.11 , pp. 41-47
    • Ghiorzo, P.1    Pensotti, V.2    Fornarini, G.3
  • 56
    • 84855518614 scopus 로고    scopus 로고
    • Prevalence of BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and pancreatic cancer
    • Stadler ZK, Salo-Mullen E, Patil SM, et al. Prevalence of BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and pancreatic cancer. Cancer. 2012;118:493-499.
    • (2012) Cancer. , vol.118 , pp. 493-499
    • Stadler, Z.K.1    Salo-Mullen, E.2    Patil, S.M.3
  • 57
    • 58549085226 scopus 로고    scopus 로고
    • BRCA germline mutations in Jewish patients with pancreatic adenocarcinoma
    • Ferrone CR, Levine DA, Tang LH, et al. BRCA germline mutations in Jewish patients with pancreatic adenocarcinoma. J Clin Oncol. 2009;27:433-438.
    • (2009) J Clin Oncol. , vol.27 , pp. 433-438
    • Ferrone, C.R.1    Levine, D.A.2    Tang, L.H.3
  • 58
    • 0037420026 scopus 로고    scopus 로고
    • BRCA2 germline mutations in familial pancreatic carcinoma
    • Hahn SA, Greenhalf B, Ellis I, et al. BRCA2 germline mutations in familial pancreatic carcinoma. J Natl Cancer Instit. 2003;95:214-221.
    • (2003) J Natl Cancer Instit. , vol.95 , pp. 214-221
    • Hahn, S.A.1    Greenhalf, B.2    Ellis, I.3
  • 59
    • 84860282103 scopus 로고    scopus 로고
    • CDKN2A is the main susceptibility gene in Italian pancreatic cancer families
    • Ghiorzo P, Fornarini G, Sciallero S, et al. CDKN2A is the main susceptibility gene in Italian pancreatic cancer families. J Med Genet. 2012;49:164-170.
    • (2012) J Med Genet. , vol.49 , pp. 164-170
    • Ghiorzo, P.1    Fornarini, G.2    Sciallero, S.3
  • 60
    • 0036895738 scopus 로고    scopus 로고
    • CDKN2A germline mutations in familial pancreatic cancer
    • Bartsch DK, Sina-Frey M, Lang S, et al. CDKN2A germline mutations in familial pancreatic cancer. Ann Surg. 2002;236:730-737.
    • (2002) Ann Surg. , vol.236 , pp. 730-737
    • Bartsch, D.K.1    Sina-Frey, M.2    Lang, S.3
  • 61
    • 0034843771 scopus 로고    scopus 로고
    • Role of disease-causing genes in sporadic pancreatic endocrine tumors: MEN1 and VHL
    • Moore PS, Missiaglia E, Antonello D, et al. Role of disease-causing genes in sporadic pancreatic endocrine tumors: MEN1 and VHL. Genes Chrom Cancer. 2001;32:177-181.
    • (2001) Genes Chrom Cancer. , vol.32 , pp. 177-181
    • Moore, P.S.1    Missiaglia, E.2    Antonello, D.3
  • 62
    • 0042131681 scopus 로고    scopus 로고
    • Germline mutations of the MEN1 gene in Korean families with multiple endocrine neoplasia type 1 (MEN1) or MEN1-related disorders
    • Park JH, Kim IJ, Kang HC, et al. Germline mutations of the MEN1 gene in Korean families with multiple endocrine neoplasia type 1 (MEN1) or MEN1-related disorders. Clin Genet. 2003;64:48-53.
    • (2003) Clin Genet. , vol.64 , pp. 48-53
    • Park, J.H.1    Kim, I.J.2    Kang, H.C.3
  • 63
    • 0033061737 scopus 로고    scopus 로고
    • A novel germline mutation of multiple endocrine neoplasia type 1 (MEN1) gene in a Japanese MEN1 patient and her daughter
    • Ohye H, Sato M, Matsubara S, et al. A novel germline mutation of multiple endocrine neoplasia type 1 (MEN1) gene in a Japanese MEN1 patient and her daughter. Endocrine J. 1999;46:325-329.
    • (1999) Endocrine J. , vol.46 , pp. 325-329
    • Ohye, H.1    Sato, M.2    Matsubara, S.3
  • 64
    • 0031758525 scopus 로고    scopus 로고
    • MEN1 gene mutations in 12 MEN1 families and their associated tumors
    • Bartsch D, Kopp I, Bergenfelz A, et al. MEN1 gene mutations in 12 MEN1 families and their associated tumors. Eur J Endocrinol. 1998; 139:416-420.
    • (1998) Eur J Endocrinol. , vol.139 , pp. 416-420
    • Bartsch, D.1    Kopp, I.2    Bergenfelz, A.3
  • 65
    • 70449521011 scopus 로고    scopus 로고
    • Germline MLH1 and MSH2 mutations in Italian pancreatic cancer patients with suspected Lynch syndrome
    • Gargiulo S, Torrini M, Ollila S, et al. Germline MLH1 and MSH2 mutations in Italian pancreatic cancer patients with suspected Lynch syndrome. Familial Cancer. 2009;8:547-553.
    • (2009) Familial Cancer. , vol.8 , pp. 547-553
    • Gargiulo, S.1    Torrini, M.2    Ollila, S.3
  • 66
    • 80053017229 scopus 로고    scopus 로고
    • Pancreatic cancer and a novel MSH2 germline alteration
    • Lindor NM, Petersen GM, Spurdle AB, et al. Pancreatic cancer and a novel MSH2 germline alteration. Pancreas. 2011;40:1138-1140.
    • (2011) Pancreas. , vol.40 , pp. 1138-1140
    • Lindor, N.M.1    Petersen, G.M.2    Spurdle, A.B.3
  • 67
    • 33750083369 scopus 로고    scopus 로고
    • Medullary carcinoma of the pancreas in a man with hereditary nonpolyposis colorectal cancer due to a mutation of the MSH2 mismatch repair gene
    • Banville N, Geraghty R, Fox E, et al. Medullary carcinoma of the pancreas in a man with hereditary nonpolyposis colorectal cancer due to a mutation of the MSH2 mismatch repair gene. Hum Pathol. 2006; 37:1498-1502.
    • (2006) Hum Pathol. , vol.37 , pp. 1498-1502
    • Banville, N.1    Geraghty, R.2    Fox, E.3
  • 68
    • 77957333720 scopus 로고    scopus 로고
    • PALB2 mutations in European familial pancreatic cancer families
    • Slater EP, Langer P, Niemczyk E, et al. PALB2 mutations in European familial pancreatic cancer families. Clin Genet. 2010;78:490-494.
    • (2010) Clin Genet. , vol.78 , pp. 490-494
    • Slater, E.P.1    Langer, P.2    Niemczyk, E.3
  • 69
    • 69349092943 scopus 로고    scopus 로고
    • Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer
    • Tischkowitz MD, Sabbaghian N, Hamel N, et al. Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer. Gastroenterology. 2009;137:1183-1186.
    • (2009) Gastroenterology. , vol.137 , pp. 1183-1186
    • Tischkowitz, M.D.1    Sabbaghian, N.2    Hamel, N.3
  • 70
    • 0030813082 scopus 로고    scopus 로고
    • Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis
    • Gorry MC, Gabbaizedeh D, Furey W, et al. Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis. Gastroenterology. 1997;113:1063-1068.
    • (1997) Gastroenterology. , vol.113 , pp. 1063-1068
    • Gorry, M.C.1    Gabbaizedeh, D.2    Furey, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.