Prediction of acetaminophen's solubility in poly(ethylene oxide) at room temperature using the Flory-Huggins theory

Drug Development and Industrial Pharmacy

Volumn 39, Issue 1, 2013, Pages 102-108

  Yang, Min ^a,e   Wang, Peng ^b,c   Gogos, Costas ^a,d  

^a NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

^b University of Rhode Island   (United States)

^c UNIVERSITY OF RHODE ISLAND   (United States)

^d Polymer Processing Institute   (United States)

^e Evonik Degussa Corp   (United States)

Author keywords

Acetaminophen paracetamol; Flory Huggins interaction parameter ; Hot melt extrusion; Poly(ethylene oxide); Solid dispersion; Solubility

Indexed keywords

MACROGOL 400; PARACETAMOL;

ARTICLE; CHEMICAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG SOLUBILITY; ENTHALPY; ENTROPY; FLORY HUGGINS LATTICE THEORY; FLOW KINETICS; MELTING POINT; MISCIBILITY; MOLECULAR WEIGHT; ROOM TEMPERATURE; THEORETICAL MODEL;

ACETAMINOPHEN; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; MODELS, CHEMICAL; POLYETHYLENE GLYCOLS; SOLUBILITY; TEMPERATURE; X-RAY DIFFRACTION;

EID: 84871187045     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2012.659188     Document Type: Article

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