The lupus-prone NZM2410/NZW strain-derived Sle1b sublocus alters the germinal center checkpoint in female mice in a B cell-intrinsic manner

Journal of Immunology

Volumn 189, Issue 12, 2012, Pages 5667-5681

  Wong, Eric B ^a,c   Khan, Tahsin N ^c   Mohan, Chandra ^b   Rahman, Ziaur S M ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; AUTOANTIBODY; CHEMOKINE RECEPTOR CXCR5; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN BCL 6;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL CYCLE CHECKPOINT; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; GENE LOCUS; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEX DIFFERENCE; SLE1B GENE; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE ACTIVATION; UPREGULATION;

ANIMALS; ANTIBODIES, ANTINUCLEAR; ANTIBODY SPECIFICITY; B-LYMPHOCYTE SUBSETS; FEMALE; GENE KNOCK-IN TECHNIQUES; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GERMINAL CENTER; IMMUNE TOLERANCE; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, INBRED NZB; MICE, KNOCKOUT; RADIATION CHIMERA;

EID: 84871162812     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201661     Document Type: Article

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