Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex i deficiency

Cell Death and Differentiation

Volumn 20, Issue 1, 2013, Pages 77-85

  Ramonet, D ^a   Perier, C ^a   Recasens, A ^a   Dehay, B ^a,f   Bove J ^a   Costa, V ^b,c   Scorrano, L ^b,c   Vila, M ^a,d,e  

^a CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^b VENETIAN INSTITUTE OF MOLECULAR MEDICINE   (Italy)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^e INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^f UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

apoptosis; MPTP; Parkinson's disease; rotenone

Indexed keywords

CYTOCHROME C; MEMBRANE PROTEIN; NEUROTOXIN; OLIGOMER; OPTIC ATROPHY 1 PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; CELL DEATH; CELL JUNCTION; COMPLEX I DEFICIENCY; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; ELECTRON MICROSCOPY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INHIBITION KINETICS; LIVER MITOCHONDRION; MOLECULAR DYNAMICS; NERVE DEGENERATION; NEUROBLASTOMA; NEUROBLASTOMA CELL; NEUROPROTECTION; NIGRONEOSTRIATAL SYSTEM; OPTIC NERVE ATROPHY; OXIDATION REDUCTION POTENTIAL; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CYTOCHROMES C; DOPAMINE; DOPAMINERGIC NEURONS; HUMANS; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NEURODEGENERATIVE DISEASES; OPTIC ATROPHY, AUTOSOMAL DOMINANT; PROTEIN TRANSPORT;

PARKINSONIA;

EID: 84871016609     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2012.95     Document Type: Article

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