Hypoxia-inducible factor-1α regulates chemotactic migration of pancreatic ductal adenocarcinoma cells through directly transactivating the CX3CR1 gene

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Zhao, Tiansuo ^a   Gao, Song ^a   Wang, Xiuchao ^a   Liu, Jingcheng ^a   Duan, Yitao ^b   Yuan, Zhanna ^a   Sheng, Jun ^a   Li, Shasha ^a   Wang, Feng ^a   Yu, Ming ^a   Ren, He ^a   Hao, Jihui ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b TIANJIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CX3CR1; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CELL HYPOXIA; CELL MIGRATION; CHEMOTAXIS; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CX3CR1 GENE; DNA STRUCTURE; GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA RESPONSIVE ELEMENT; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; TRANSACTIVATION;

ADENOCARCINOMA; ANIMALS; ANOXIA; CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TUMOR; CHEMOTAXIS; CHROMATIN; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIGANDS; MICE; MICE, NUDE; MICROSCOPY, CONFOCAL; NEOPLASM METASTASIS; PANCREATIC NEOPLASMS; PROMOTER REGIONS, GENETIC; RECEPTORS, CHEMOKINE; RNA, SMALL INTERFERING;

EID: 84865415804     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043399     Document Type: Article

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