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Volumn 7, Issue 12, 2012, Pages

Brain Gene Expression of a Sporadic (icv-STZ Mouse) and a Familial Mouse Model (3xTg-AD Mouse) of Alzheimer's Disease

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; PRESENILIN; PROTEIN KINASE; STREPTOZOCIN; TAU PROTEIN;

EID: 84870940064     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051432     Document Type: Article
Times cited : (63)

References (59)
  • 1
    • 78650462753 scopus 로고    scopus 로고
    • Alzheimer's disease: a general introduction and pathomechanism
    • Finder VH, (2010) Alzheimer's disease: a general introduction and pathomechanism. J Alzheimers Dis 22Suppl 3: 5-19.
    • (2010) J Alzheimers Dis , vol.22 , pp. 5-19
    • Finder, V.H.1
  • 2
    • 84858225391 scopus 로고    scopus 로고
    • 2012 Alzheimer's disease facts and figures
    • Association Association
    • Association Association, (2012) 2012 Alzheimer's disease facts and figures. Alzheimers Dement 8: 131-168.
    • (2012) Alzheimers Dement , vol.8 , pp. 131-168
  • 3
    • 0042697305 scopus 로고    scopus 로고
    • Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction
    • Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, et al. (2003) Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 39: 409-421.
    • (2003) Neuron , vol.39 , pp. 409-421
    • Oddo, S.1    Caccamo, A.2    Shepherd, J.D.3    Murphy, M.P.4    Golde, T.E.5
  • 4
    • 0344845132 scopus 로고    scopus 로고
    • Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease
    • Oddo S, Caccamo A, Kitazawa M, Tseng BP, LaFerla FM, (2003) Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiol Aging 24: 1063-1070.
    • (2003) Neurobiol Aging , vol.24 , pp. 1063-1070
    • Oddo, S.1    Caccamo, A.2    Kitazawa, M.3    Tseng, B.P.4    LaFerla, F.M.5
  • 5
    • 51049120310 scopus 로고    scopus 로고
    • Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice
    • Mastrangelo MA, Bowers WJ, (2008) Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice. BMC Neurosci 9: 81.
    • (2008) BMC Neurosci , vol.9 , pp. 81
    • Mastrangelo, M.A.1    Bowers, W.J.2
  • 6
    • 14244253319 scopus 로고    scopus 로고
    • Metabolic/signal transduction hypothesis of Alzheimer's disease and other tauopathies
    • Iqbal K, Grundke-Iqbal I, (2005) Metabolic/signal transduction hypothesis of Alzheimer's disease and other tauopathies. Acta Neuropathol 109: 25-31.
    • (2005) Acta Neuropathol , vol.109 , pp. 25-31
    • Iqbal, K.1    Grundke-Iqbal, I.2
  • 7
    • 0026406816 scopus 로고
    • Abnormalities of energy metabolism in Alzheimer's disease studied with PET
    • Heiss WD, Szelies B, Kessler J, Herholz K, (1991) Abnormalities of energy metabolism in Alzheimer's disease studied with PET. Ann N Y Acad Sci 640: 65-71.
    • (1991) Ann N Y Acad Sci , vol.640 , pp. 65-71
    • Heiss, W.D.1    Szelies, B.2    Kessler, J.3    Herholz, K.4
  • 8
    • 33646002650 scopus 로고    scopus 로고
    • Impaired brain glucose metabolism leads to Alzheimer neurofibrillary degeneration through a decrease in tau O-GlcNAcylation
    • Gong CX, Liu F, Grundke-Iqbal I, Iqbal K, (2006) Impaired brain glucose metabolism leads to Alzheimer neurofibrillary degeneration through a decrease in tau O-GlcNAcylation. J Alzheimers Dis 9: 1-12.
    • (2006) J Alzheimers Dis , vol.9 , pp. 1-12
    • Gong, C.X.1    Liu, F.2    Grundke-Iqbal, I.3    Iqbal, K.4
  • 9
    • 79960896430 scopus 로고    scopus 로고
    • Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes
    • Liu Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX, (2011) Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes. J Pathol 225: 54-62.
    • (2011) J Pathol , vol.225 , pp. 54-62
    • Liu, Y.1    Liu, F.2    Grundke-Iqbal, I.3    Iqbal, K.4    Gong, C.X.5
  • 10
    • 15244351255 scopus 로고    scopus 로고
    • Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes?
    • Steen E, Terry BM, Rivera EJ, Cannon JL, Neely TR, et al. (2005) Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes? J Alzheimers Dis 7: 63-80.
    • (2005) J Alzheimers Dis , vol.7 , pp. 63-80
    • Steen, E.1    Terry, B.M.2    Rivera, E.J.3    Cannon, J.L.4    Neely, T.R.5
  • 11
    • 68949089312 scopus 로고    scopus 로고
    • Alzheimer's disease is type 3 diabetes-evidence reviewed
    • de la Monte SM, Wands JR, (2008) Alzheimer's disease is type 3 diabetes-evidence reviewed. J Diabetes Sci Technol 2: 1101-1113.
    • (2008) J Diabetes Sci Technol , vol.2 , pp. 1101-1113
    • de la Monte, S.M.1    Wands, J.R.2
  • 12
    • 73649112749 scopus 로고    scopus 로고
    • Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease
    • Deng Y, Li B, Liu Y, Iqbal K, Grundke-Iqbal I, et al. (2009) Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease. Am J Pathol 175: 2089-2098.
    • (2009) Am J Pathol , vol.175 , pp. 2089-2098
    • Deng, Y.1    Li, B.2    Liu, Y.3    Iqbal, K.4    Grundke-Iqbal, I.5
  • 13
    • 34247324303 scopus 로고    scopus 로고
    • Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein
    • Grunblatt E, Salkovic-Petrisic M, Osmanovic J, Riederer P, Hoyer S, (2007) Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein. J Neurochem 101: 757-770.
    • (2007) J Neurochem , vol.101 , pp. 757-770
    • Grunblatt, E.1    Salkovic-Petrisic, M.2    Osmanovic, J.3    Riederer, P.4    Hoyer, S.5
  • 14
    • 33645100144 scopus 로고    scopus 로고
    • Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway
    • Salkovic-Petrisic M, Tribl F, Schmidt M, Hoyer S, Riederer P, (2006) Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway. J Neurochem 96: 1005-1015.
    • (2006) J Neurochem , vol.96 , pp. 1005-1015
    • Salkovic-Petrisic, M.1    Tribl, F.2    Schmidt, M.3    Hoyer, S.4    Riederer, P.5
  • 15
    • 79956215794 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer's disease: a long-term follow up study
    • Salkovic-Petrisic M, Osmanovic-Barilar J, Bruckner MK, Hoyer S, Arendt T, et al. (2011) Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer's disease: a long-term follow up study. J Neural Transm 118: 765-772.
    • (2011) J Neural Transm , vol.118 , pp. 765-772
    • Salkovic-Petrisic, M.1    Osmanovic-Barilar, J.2    Bruckner, M.K.3    Hoyer, S.4    Arendt, T.5
  • 16
    • 67349213205 scopus 로고    scopus 로고
    • Synaptic degeneration in Alzheimer's disease
    • Arendt T, (2009) Synaptic degeneration in Alzheimer's disease. Acta Neuropathol 118: 167-179.
    • (2009) Acta Neuropathol , vol.118 , pp. 167-179
    • Arendt, T.1
  • 17
    • 0025987048 scopus 로고
    • Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment
    • Terry RD, Masliah E, Salmon DP, Butters N, DeTeresa R, et al. (1991) Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 30: 572-580.
    • (1991) Ann Neurol , vol.30 , pp. 572-580
    • Terry, R.D.1    Masliah, E.2    Salmon, D.P.3    Butters, N.4    DeTeresa, R.5
  • 18
    • 33746126134 scopus 로고    scopus 로고
    • Implication of calpain in neuronal apoptosis. A possible regulation of Alzheimer's disease
    • Raynaud F, Marcilhac A, (2006) Implication of calpain in neuronal apoptosis. A possible regulation of Alzheimer's disease. FEBS J 273: 3437-3443.
    • (2006) FEBS J , vol.273 , pp. 3437-3443
    • Raynaud, F.1    Marcilhac, A.2
  • 19
    • 79960822419 scopus 로고    scopus 로고
    • Autophagy in aging and Alzheimer's disease: pathologic or protective?
    • Barnett A, Brewer GJ, (2011) Autophagy in aging and Alzheimer's disease: pathologic or protective? J Alzheimers Dis 25: 385-394.
    • (2011) J Alzheimers Dis , vol.25 , pp. 385-394
    • Barnett, A.1    Brewer, G.J.2
  • 21
    • 53749096967 scopus 로고    scopus 로고
    • Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration
    • Vosler PS, Brennan CS, Chen J, (2008) Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration. Mol Neurobiol 38: 78-100.
    • (2008) Mol Neurobiol , vol.38 , pp. 78-100
    • Vosler, P.S.1    Brennan, C.S.2    Chen, J.3
  • 22
    • 27844553889 scopus 로고    scopus 로고
    • Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain
    • Liu F, Grundke-Iqbal I, Iqbal K, Oda Y, Tomizawa K, et al. (2005) Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain. J Biol Chem 280: 37755-37762.
    • (2005) J Biol Chem , vol.280 , pp. 37755-37762
    • Liu, F.1    Grundke-Iqbal, I.2    Iqbal, K.3    Oda, Y.4    Tomizawa, K.5
  • 23
    • 0042736668 scopus 로고    scopus 로고
    • Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study
    • Drzezga A, Lautenschlager N, Siebner H, Riemenschneider M, Willoch F, et al. (2003) Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study. Eur J Nucl Med Mol Imaging 30: 1104-1113.
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , pp. 1104-1113
    • Drzezga, A.1    Lautenschlager, N.2    Siebner, H.3    Riemenschneider, M.4    Willoch, F.5
  • 24
    • 72449187655 scopus 로고    scopus 로고
    • The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways
    • Zeidan Q, Hart GW The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways. J Cell Sci 123: 13-22.
    • J Cell Sci , vol.123 , pp. 13-22
    • Zeidan, Q.1    Hart, G.W.2
  • 25
    • 33644874204 scopus 로고    scopus 로고
    • The hexosamine signaling pathway: deciphering the "O-GlcNAc code"
    • Love DC, Hanover JA, (2005) The hexosamine signaling pathway: deciphering the "O-GlcNAc code". Sci STKE 2005: re13.
    • (2005) Sci STKE , vol.2005
    • Love, D.C.1    Hanover, J.A.2
  • 26
    • 84856496197 scopus 로고    scopus 로고
    • Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease
    • de la Monte SM, (2012) Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease. Curr Alzheimer Res 9: 35-66.
    • (2012) Curr Alzheimer Res , vol.9 , pp. 35-66
    • de la Monte, S.M.1
  • 27
    • 42249107130 scopus 로고    scopus 로고
    • Brain insulin, energy and glucose homeostasis; genes, environment and metabolic pathologies
    • Gerozissis K, (2008) Brain insulin, energy and glucose homeostasis; genes, environment and metabolic pathologies. Eur J Pharmacol 585: 38-49.
    • (2008) Eur J Pharmacol , vol.585 , pp. 38-49
    • Gerozissis, K.1
  • 28
    • 70349581633 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer's disease
    • de la Monte SM, (2009) Insulin resistance and Alzheimer's disease. BMB Rep 42: 475-481.
    • (2009) BMB Rep , vol.42 , pp. 475-481
    • de la Monte, S.M.1
  • 29
    • 78650651998 scopus 로고    scopus 로고
    • Insulin resistance and hippocampal volume in women at risk for Alzheimer's disease
    • Rasgon NL, Kenna HA, Wroolie TE, Kelley R, Silverman D, et al. (2011) Insulin resistance and hippocampal volume in women at risk for Alzheimer's disease. Neurobiol Aging 32: 1942-1948.
    • (2011) Neurobiol Aging , vol.32 , pp. 1942-1948
    • Rasgon, N.L.1    Kenna, H.A.2    Wroolie, T.E.3    Kelley, R.4    Silverman, D.5
  • 30
    • 38149062059 scopus 로고    scopus 로고
    • Role of mTOR in physiology and pathology of the nervous system
    • Swiech L, Perycz M, Malik A, Jaworski J, (2008) Role of mTOR in physiology and pathology of the nervous system. Biochim Biophys Acta 1784: 116-132.
    • (2008) Biochim Biophys Acta , vol.1784 , pp. 116-132
    • Swiech, L.1    Perycz, M.2    Malik, A.3    Jaworski, J.4
  • 31
    • 21344459656 scopus 로고    scopus 로고
    • mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease
    • Lafay-Chebassier C, Paccalin M, Page G, Barc-Pain S, Perault-Pochat MC, et al. (2005) mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease. J Neurochem 94: 215-225.
    • (2005) J Neurochem , vol.94 , pp. 215-225
    • Lafay-Chebassier, C.1    Paccalin, M.2    Page, G.3    Barc-Pain, S.4    Perault-Pochat, M.C.5
  • 32
    • 33744925947 scopus 로고    scopus 로고
    • Mapping cellular transcriptosomes in autopsied Alzheimer's disease subjects and relevant animal models
    • Reddy PH, McWeeney S, (2006) Mapping cellular transcriptosomes in autopsied Alzheimer's disease subjects and relevant animal models. Neurobiol Aging 27: 1060-1077.
    • (2006) Neurobiol Aging , vol.27 , pp. 1060-1077
    • Reddy, P.H.1    McWeeney, S.2
  • 33
    • 77049100748 scopus 로고    scopus 로고
    • Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice
    • Plaschke K, Kopitz J, Siegelin M, Schliebs R, Salkovic-Petrisic M,et al. Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice. J Alzheimers Dis 19: 691-704.
    • J Alzheimers Dis , vol.19 , pp. 691-704
    • Plaschke, K.1    Kopitz, J.2    Siegelin, M.3    Schliebs, R.4    Salkovic-Petrisic, M.5
  • 34
    • 84858321928 scopus 로고    scopus 로고
    • Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling
    • Nizzari M, Thellung S, Corsaro A, Villa V, Pagano A, et al. (2012) Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling. J Toxicol 2012: 187297.
    • (2012) J Toxicol , vol.2012 , pp. 187297
    • Nizzari, M.1    Thellung, S.2    Corsaro, A.3    Villa, V.4    Pagano, A.5
  • 35
    • 0030761094 scopus 로고    scopus 로고
    • The presenilins and Alzheimer's disease
    • Hutton M, Hardy J, (1997) The presenilins and Alzheimer's disease. Hum Mol Genet 6: 1639-1646.
    • (1997) Hum Mol Genet , vol.6 , pp. 1639-1646
    • Hutton, M.1    Hardy, J.2
  • 36
    • 38449113274 scopus 로고    scopus 로고
    • Transcriptional regulation of the presenilin-1 gene: implication in Alzheimer's disease
    • Das HK, (2008) Transcriptional regulation of the presenilin-1 gene: implication in Alzheimer's disease. Front Biosci 13: 822-832.
    • (2008) Front Biosci , vol.13 , pp. 822-832
    • Das, H.K.1
  • 37
    • 43149088503 scopus 로고    scopus 로고
    • Loss of presenilin function causes Alzheimer's disease-like neurodegeneration in the mouse
    • Chen Q, Nakajima A, Choi SH, Xiong X, Tang YP, (2008) Loss of presenilin function causes Alzheimer's disease-like neurodegeneration in the mouse. J Neurosci Res 86: 1615-1625.
    • (2008) J Neurosci Res , vol.86 , pp. 1615-1625
    • Chen, Q.1    Nakajima, A.2    Choi, S.H.3    Xiong, X.4    Tang, Y.P.5
  • 38
    • 33846282302 scopus 로고    scopus 로고
    • The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism
    • Shen J, Kelleher RJ, 3rd (2007) The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism. Proc Natl Acad Sci U S A 104: 403-409.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 403-409
    • Shen, J.1    Kelleher 3rd, R.J.2
  • 39
    • 11144354609 scopus 로고    scopus 로고
    • Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration
    • Saura CA, Choi SY, Beglopoulos V, Malkani S, Zhang D, et al. (2004) Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration. Neuron 42: 23-36.
    • (2004) Neuron , vol.42 , pp. 23-36
    • Saura, C.A.1    Choi, S.Y.2    Beglopoulos, V.3    Malkani, S.4    Zhang, D.5
  • 40
    • 78149259168 scopus 로고    scopus 로고
    • Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunction
    • Zhang D, Zhang C, Ho A, Kirkwood A, Sudhof TC, et al. (2010) Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunction. J Neurochem 115: 1215-1221.
    • (2010) J Neurochem , vol.115 , pp. 1215-1221
    • Zhang, D.1    Zhang, C.2    Ho, A.3    Kirkwood, A.4    Sudhof, T.C.5
  • 41
    • 67949086707 scopus 로고    scopus 로고
    • Presenilins are essential for regulating neurotransmitter release
    • Zhang C, Wu B, Beglopoulos V, Wines-Samuelson M, Zhang D, et al. (2009) Presenilins are essential for regulating neurotransmitter release. Nature 460: 632-636.
    • (2009) Nature , vol.460 , pp. 632-636
    • Zhang, C.1    Wu, B.2    Beglopoulos, V.3    Wines-Samuelson, M.4    Zhang, D.5
  • 43
    • 78149414428 scopus 로고    scopus 로고
    • Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Abeta and tau pathologies in 3xTg-AD mice
    • Blanchard J, Wanka L, Tung YC, Cardenas-Aguayo Mdel C, LaFerla FM, et al. (2010) Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Abeta and tau pathologies in 3xTg-AD mice. Acta Neuropathol 120: 605-621.
    • (2010) Acta Neuropathol , vol.120 , pp. 605-621
    • Blanchard, J.1    Wanka, L.2    Tung, Y.C.3    Cardenas-Aguayo Mdel, C.4    LaFerla, F.M.5
  • 44
    • 1542343843 scopus 로고    scopus 로고
    • Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity
    • Weinstock M, Shoham S, (2004) Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity. J Neural Transm 111: 347-366.
    • (2004) J Neural Transm , vol.111 , pp. 347-366
    • Weinstock, M.1    Shoham, S.2
  • 45
    • 0025911018 scopus 로고
    • Advances in Alzheimer's disease
    • Katzman R, Saitoh T, (1991) Advances in Alzheimer's disease. FASEB J 5: 278-286.
    • (1991) FASEB J , vol.5 , pp. 278-286
    • Katzman, R.1    Saitoh, T.2
  • 46
    • 79954573504 scopus 로고    scopus 로고
    • The role of CREB signaling in Alzheimer's disease and other cognitive disorders
    • Saura CA, Valero J, (2011) The role of CREB signaling in Alzheimer's disease and other cognitive disorders. Rev Neurosci 22: 153-169.
    • (2011) Rev Neurosci , vol.22 , pp. 153-169
    • Saura, C.A.1    Valero, J.2
  • 47
    • 80051988063 scopus 로고    scopus 로고
    • Constitutive cAMP response element binding protein (CREB) activation by Alzheimer's disease presenilin-driven inositol trisphosphate receptor (InsP3R) Ca2+ signaling
    • Muller M, Cardenas C, Mei L, Cheung KH, Foskett JK, (2011) Constitutive cAMP response element binding protein (CREB) activation by Alzheimer's disease presenilin-driven inositol trisphosphate receptor (InsP3R) Ca2+ signaling. Proc Natl Acad Sci U S A 108: 13293-13298.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 13293-13298
    • Muller, M.1    Cardenas, C.2    Mei, L.3    Cheung, K.H.4    Foskett, J.K.5
  • 49
    • 79958766042 scopus 로고    scopus 로고
    • Mechanisms of specificity in neuronal activity-regulated gene transcription
    • Lyons MR, West AE, (2011) Mechanisms of specificity in neuronal activity-regulated gene transcription. Prog Neurobiol 94: 259-295.
    • (2011) Prog Neurobiol , vol.94 , pp. 259-295
    • Lyons, M.R.1    West, A.E.2
  • 50
    • 33845293444 scopus 로고    scopus 로고
    • Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease
    • Brooks WM, Lynch PJ, Ingle CC, Hatton A, Emson PC, et al. (2007) Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease. Brain Res 1127: 127-135.
    • (2007) Brain Res , vol.1127 , pp. 127-135
    • Brooks, W.M.1    Lynch, P.J.2    Ingle, C.C.3    Hatton, A.4    Emson, P.C.5
  • 51
    • 79958757543 scopus 로고    scopus 로고
    • Alterations of brain and cerebellar proteomes linked to Abeta and tau pathology in a female triple-transgenic murine model of Alzheimer's disease
    • Ciavardelli D, Silvestri E, Del Viscovo A, Bomba M, De Gregorio D, et al. (2010) Alterations of brain and cerebellar proteomes linked to Abeta and tau pathology in a female triple-transgenic murine model of Alzheimer's disease. Cell Death Dis 1: e90.
    • (2010) Cell Death Dis , vol.1
    • Ciavardelli, D.1    Silvestri, E.2    Del Viscovo, A.3    Bomba, M.4    De Gregorio, D.5
  • 52
    • 70349216418 scopus 로고    scopus 로고
    • Brain glucose transporters, O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer's disease
    • Liu Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX, (2009) Brain glucose transporters, O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer's disease. J Neurochem 111: 242-249.
    • (2009) J Neurochem , vol.111 , pp. 242-249
    • Liu, Y.1    Liu, F.2    Grundke-Iqbal, I.3    Iqbal, K.4    Gong, C.X.5
  • 53
    • 38049050725 scopus 로고    scopus 로고
    • Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease
    • Liu Y, Liu F, Iqbal K, Grundke-Iqbal I, Gong CX, (2008) Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease. FEBS Lett 582: 359-364.
    • (2008) FEBS Lett , vol.582 , pp. 359-364
    • Liu, Y.1    Liu, F.2    Iqbal, K.3    Grundke-Iqbal, I.4    Gong, C.X.5
  • 54
    • 0032487335 scopus 로고    scopus 로고
    • Immunocytochemical localization of the insulin-responsive glucose transporter 4 (Glut4) in the rat central nervous system
    • El Messari S, Leloup C, Quignon M, Brisorgueil MJ, Penicaud L, et al. (1998) Immunocytochemical localization of the insulin-responsive glucose transporter 4 (Glut4) in the rat central nervous system. J Comp Neurol 399: 492-512.
    • (1998) J Comp Neurol , vol.399 , pp. 492-512
    • El Messari, S.1    Leloup, C.2    Quignon, M.3    Brisorgueil, M.J.4    Penicaud, L.5
  • 55
    • 65549107435 scopus 로고    scopus 로고
    • Cerebellar neurons possess a vesicular compartment structurally and functionally similar to Glut4-storage vesicles from peripheral insulin-sensitive tissues
    • Bakirtzi K, Belfort G, Lopez-Coviella I, Kuruppu D, Cao L, et al. (2009) Cerebellar neurons possess a vesicular compartment structurally and functionally similar to Glut4-storage vesicles from peripheral insulin-sensitive tissues. J Neurosci 29: 5193-5201.
    • (2009) J Neurosci , vol.29 , pp. 5193-5201
    • Bakirtzi, K.1    Belfort, G.2    Lopez-Coviella, I.3    Kuruppu, D.4    Cao, L.5
  • 56
    • 70349285955 scopus 로고    scopus 로고
    • Insulin-stimulated translocation of GLUT4 to the plasma membrane in rat hippocampus is PI3-kinase dependent
    • Grillo CA, Piroli GG, Hendry RM, Reagan LP, (2009) Insulin-stimulated translocation of GLUT4 to the plasma membrane in rat hippocampus is PI3-kinase dependent. Brain Res 1296: 35-45.
    • (2009) Brain Res , vol.1296 , pp. 35-45
    • Grillo, C.A.1    Piroli, G.G.2    Hendry, R.M.3    Reagan, L.P.4
  • 58
    • 78651274000 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes
    • Baker LD, Cross DJ, Minoshima S, Belongia D, Watson GS, et al. (2011) Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes. Arch Neurol 68: 51-57.
    • (2011) Arch Neurol , vol.68 , pp. 51-57
    • Baker, L.D.1    Cross, D.J.2    Minoshima, S.3    Belongia, D.4    Watson, G.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.