Metabolic/signal transduction hypothesis of Alzheimer's disease and other tauopathies

Acta Neuropathologica

Volumn 109, Issue 1, 2005, Pages 25-31

  Iqbal, Khalid ^a   Grundke Iqbal, Inge ^a  

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Alzheimer's disease; Microtubule associated protein tau; Neurofibrillary degeneration; Signal transduction; Tauopathies

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CALCIUM; CALMODULIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN DEPENDENT KINASE 5; GLYCOGEN SYNTHASE KINASE 3; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 2; NEUROFILAMENT PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PRESENILIN 1; PRESENILIN 2; TAU PROTEIN;

ALZHEIMER DISEASE; BRAIN METABOLISM; CELL MEMBRANE FLUIDITY; DEMENTIA; ENVIRONMENTAL FACTOR; EXPERIMENTAL ANIMAL; GENE MUTATION; GENETIC DISORDER; HUMAN; HYPOTHESIS; MISSENSE MUTATION; MOLECULAR MECHANICS; NERVE CELL MEMBRANE; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; TAUOPATHY; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; ANIMALS; HUMANS; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; TAUOPATHIES;

EID: 14244253319     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-004-0951-y     Document Type: Review

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