-
1
-
-
0023132387
-
Characterization and chromosomal localization of a cDNA encodingbrain amyloid of Alzheimer's disease
-
Goldgaber D, Lerman M I, McBride O W, et al. Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. Science, 1987, 235(4791): 877-880 (Pubitemid 17019124)
-
(1987)
Science
, vol.235
, Issue.4791
, pp. 877-880
-
-
Goldgaber, D.1
Lerman, M.I.2
McBride, O.W.3
-
2
-
-
2142777413
-
Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides
-
DOI 10.1073/pnas.84.12.4190
-
Robakis N K, Ramakrishna N, Wolfe G, et al. Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides. Proc Natl Acad Sci USA, 1987, 84(12): 4190-4194 (Pubitemid 17090899)
-
(1987)
Proceedings of the National Academy of Sciences of the United States of America
, vol.84
, Issue.12
, pp. 4190-4194
-
-
Robakis, N.K.1
Ramakrishna, N.2
Wolfe, G.3
Wisniewski, H.M.4
-
3
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
DOI 10.1038/325733a0
-
Kang J, Lemaire H G, Unterbeck A, et al. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature, 1987, 325(6106): 733-736 (Pubitemid 17054046)
-
(1987)
Nature
, vol.325
, Issue.6106
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.-G.2
Unterbeck, A.3
-
4
-
-
0033382226
-
Identification of a novel aspartic protease (Asp 2) as β-secretase
-
DOI 10.1006/mcne.1999.0811
-
Hussain I, Powell D, Howlett D R, et al. Identification of a novel aspartic protease (Asp 2) as beta-secretase. Mol Cell Neurosci, 1999, 14(6): 419-427 (Pubitemid 30026585)
-
(1999)
Molecular and Cellular Neurosciences
, vol.14
, Issue.6
, pp. 419-427
-
-
Hussain, I.1
Powell, D.2
Howlett, D.R.3
Tew, D.G.4
Meek, T.D.5
Chapman, C.6
Gloger, I.S.7
Murphy, K.E.8
Southan, C.D.9
Ryan, D.M.10
Smith, T.S.11
Simmons, D.L.12
Walsh, F.S.13
Dingwall, C.14
Christie, G.15
-
5
-
-
0033518251
-
Purification and cloning of amyloid precursor protein beta-secretase from human brain
-
Sinha S, Anderson J P, Barbour R, et al. Purification and cloning of amyloid precursor protein beta-secretase from human brain. Nature, 1999, 402( 6761): 537-540
-
(1999)
Nature
, vol.402
, Issue.6761
, pp. 537-540
-
-
Sinha, S.1
Anderson, J.P.2
Barbour, R.3
-
6
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R, Bennett B D, Babu-Khan S, et al. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science, 1999, 286( 5440): 735-741
-
(1999)
Science
, vol.286
, Issue.5440
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
-
7
-
-
0035853821
-
A splice variant of betasecretase deficient in the amyloidogenic processing of the amyloid precursor protein
-
Bodendorf U, Fischer F, Bodian D, et al. A splice variant of betasecretase deficient in the amyloidogenic processing of the amyloid precursor protein. J Biol Chem, 2001, 276( 15): 12019-12023
-
(2001)
J Biol Chem
, vol.276
, Issue.15
, pp. 12019-12023
-
-
Bodendorf, U.1
Fischer, F.2
Bodian, D.3
-
8
-
-
0035971166
-
The pro domain of beta-secretase does not confer strict zymogen-like properties but does assist proper folding of the protease domain
-
Shi X P, Chen E, Yin K C, et al. The pro domain of beta-secretase does not confer strict zymogen-like properties but does assist proper folding of the protease domain. J Biol Chem, 2001, 276 ( 13): 10366-10373
-
(2001)
J Biol Chem
, vol.276
, Issue.13
, pp. 10366-10373
-
-
Shi, X.P.1
Chen, E.2
Yin, K.C.3
-
9
-
-
79959196089
-
Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and gamma-secretase
-
Hogl S, Kuhn P H, Colombo A, et al. Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and gamma-secretase. PLoS One, 2011, 6( 6): e21337
-
(2011)
PLoS One
, vol.6
, Issue.6
-
-
Hogl, S.1
Kuhn, P.H.2
Colombo, A.3
-
10
-
-
7444250507
-
Degradation of BACE by the ubiquitin-proteasome pathway
-
Qing H, Zhou W, Christensen M A, el al. Degradation of BACE by the ubiquitin-proteasome pathway. Faseb J, 2004, 18( 13): 1571-1573
-
(2004)
Faseb J
, vol.18
, Issue.13
, pp. 1571-1573
-
-
Qing, H.1
Zhou, W.2
Christensen, M.A.3
-
11
-
-
34249734831
-
Depletion of GGA3 stabilizes BACE and enhances β-secretase activity
-
DOI 10.1016/j.neuron.2007.05.012, PII S0896627307003467
-
Tesco G, Koh Y H, Kang E L, et al. Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity. Neuron, 2007, 54(5): 721-737 (Pubitemid 46843521)
-
(2007)
Neuron
, vol.54
, Issue.5
, pp. 721-737
-
-
Tesco, G.1
Koh, Y.H.2
Kang, E.L.3
Cameron, A.N.4
Das, S.5
Sena-Esteves, M.6
Hiltunen, M.7
Yang, S.-H.8
Zhong, Z.9
Shen, Y.10
Simpkins, J.W.11
Tanzi, R.E.12
-
12
-
-
0347356360
-
Transcriptional regulation of BACE1, the β-amyloid precursor protein β-secretase, by Sp1
-
DOI 10.1128/MCB.24.2.865-874.2004
-
Christensen M A, Zhou W, Qing H, et al. Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1. Mol Cell Biol, 2004, 24(2): 865-874 (Pubitemid 38057936)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.2
, pp. 865-874
-
-
Christensen, M.A.1
Zhou, W.2
Qing, H.3
Lehman, A.4
Philipsen, S.5
Song, W.6
-
13
-
-
67649220624
-
Constitutive JAK2/STAT1 activation regulates endogenous BACE1 expression in neurons
-
Cho H J, Jin S M, Son S M, et al. Constitutive JAK2/STAT1 activation regulates endogenous BACE1 expression in neurons. Biochem Biophys Res Commun, 2009, 386( 1): 175-180
-
(2009)
Biochem Biophys Res Commun
, vol.386
, Issue.1
, pp. 175-180
-
-
Cho, H.J.1
Jin, S.M.2
Son, S.M.3
-
14
-
-
40549129366
-
Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling
-
DOI 10.1111/j.1474-9726.2007.00360.x
-
Cho H J, Jin S M, Youn H D, et al. Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling. Aging Cell, 2008, 7(2): 137-147 (Pubitemid 351359647)
-
(2008)
Aging Cell
, vol.7
, Issue.2
, pp. 137-147
-
-
Cho, H.-J.1
Jin, S.M.2
Youn, H.D.3
Huh, K.4
Mook-Jung, I.5
-
15
-
-
84856428468
-
Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease
-
Chen C H, Zhou W, Liu S, et al. Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease. Int J Neuropsychopharmacol, 2012, 15( 1): 77-90
-
(2012)
Int J Neuropsychopharmacol
, vol.15
, Issue.1
, pp. 77-90
-
-
Chen, C.H.1
Zhou, W.2
Liu, S.3
-
16
-
-
33644920657
-
Control of APP processing and Aβ generation level by BACE1 enzymatic activity and transcription
-
DOI 10.1096/fj.05-4986com
-
Li Y, Zhou W, Tong Y, et al. Control of APP processing and Abeta generation level by BACE1 enzymatic activity and transcription. Faseb J, 2006, 20(2): 285-292 (Pubitemid 44933176)
-
(2006)
FASEB Journal
, vol.20
, Issue.2
, pp. 285-292
-
-
Li, Y.1
Zhou, W.2
Tong, Y.3
He, G.4
Song, W.5
-
17
-
-
40249114794
-
Transcriptional Regulation of β-Secretase by p25/cdk5 leads to enhanced amyloidogenic processing
-
DOI 10.1016/j.neuron.2008.02.024, PII S0896627308001785
-
Wen Y, Yu W H, Maloney B, et al. Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing. Neuron, 2008, 57(5): 680-690 (Pubitemid 351335351)
-
(2008)
Neuron
, vol.57
, Issue.5
, pp. 680-690
-
-
Wen, Y.1
Yu, W.H.2
Maloney, B.3
Bailey, J.4
Ma, J.5
Marie, I.6
Maurin, T.7
Wang, L.8
Figueroa, H.9
Herman, M.10
Krishnamurthy, P.11
Liu, L.12
Planel, E.13
Lau, L.-F.14
Lahiri, D.K.15
Duff, K.16
-
18
-
-
33646244775
-
Leaky scanning and reinitiation regulate BACE1 gene expression
-
Zhou W, Song W. Leaky scanning and reinitiation regulate BACE1 gene expression. Mol Cell Biol, 2006, 26( 9): 3353-3364
-
(2006)
Mol Cell Biol
, vol.26
, Issue.9
, pp. 3353-3364
-
-
Zhou, W.1
Song, W.2
-
19
-
-
0035798269
-
Amyloid β secretase gene (BACE) is neither mutated in nor associated with early-onset Alzheimer's disease
-
DOI 10.1016/S0304-3940(01)02234-0, PII S0304394001022340
-
Cruts M, Dermaut B, Rademakers R, et al. Amyloid beta secretase gene (BACE) is neither mutated in nor associated with early-onset Alzheimer's disease. Neurosci Lett, 2001, 313(1-2): 105-107 (Pubitemid 32973906)
-
(2001)
Neuroscience Letters
, vol.313
, Issue.1-2
, pp. 105-107
-
-
Cruts, M.1
Dermaut, B.2
Rademakers, R.3
Roks, G.4
Van Den, B.M.5
Munteanu, G.6
Van Duijn, C.M.7
Van Broeckhoven, C.8
-
20
-
-
33746572249
-
Increased BACE1 maturation contributes to the pathogenesis of Alzheimer's disease in down syndrome
-
DOI 10.1096/fj.05-5628com
-
Sun X, Tong Y, Qing H, et al. Increased BACE1 maturation contributes to the pathogenesis of Alzheimer's disease in Down syndrome. Faseb J, 2006, 20(9):1361-1368 (Pubitemid 44943844)
-
(2006)
FASEB Journal
, vol.20
, Issue.9
, pp. 1361-1368
-
-
Sun, X.1
Tong, Y.2
Qing, H.3
Chen, C.-H.4
Song, W.5
-
21
-
-
0031054674
-
Brain infarction and the clinical expression of Alzheimer disease: The nun study
-
Snowdon D A, Greiner L H, Mortimer J A, et al. Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. Jama, 1997, 277(10): 813-817 (Pubitemid 27111317)
-
(1997)
Journal of the American Medical Association
, vol.277
, Issue.10
, pp. 813-817
-
-
Snowdon, D.A.1
Greiner, L.H.2
Mortimer, J.A.3
Riley, K.P.4
Greiner, P.A.5
Markesbery, W.R.6
-
22
-
-
33845505233
-
Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expession
-
DOI 10.1073/pnas.0606298103
-
Sun X, He G, Qing H, et al. Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression. Proc Natl Acad Sci USA, 2006, 103(49): 18727-18732 (Pubitemid 44913478)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.49
, pp. 18727-18732
-
-
Sun, X.1
He, G.2
Qing, H.3
Zhou, W.4
Dobie, F.5
Cai, F.6
Staufenbiel, M.7
Huang, L.E.8
Song, W.9
-
23
-
-
0025739254
-
Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-B transcription factor and HIV-1
-
Schreck R, Rieber P, Baeuerle P A. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. Embo J, 1991, 10(8): 2247-2258 (Pubitemid 21905698)
-
(1991)
EMBO Journal
, vol.10
, Issue.8
, pp. 2247-2258
-
-
Schreck, R.1
Rieber, P.2
Baeuerle, P.A.3
-
24
-
-
0028982454
-
Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease
-
Motter R, Vigo-Pelfrey C, Kholodenko D, et al. Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease. Ann Neurol, 1995, 38( 4): 643-648
-
(1995)
Ann Neurol
, vol.38
, Issue.4
, pp. 643-648
-
-
Motter, R.1
Vigo-Pelfrey, C.2
Kholodenko, D.3
-
25
-
-
0141738373
-
CSF markers for incipient Alzheimer's disease
-
DOI 10.1016/S1474-4422(03)00530-1
-
Blennow K, Hampel H. CSF markers for incipient Alzheimer's disease. Lancet Neurol, 2003, 2(10): 605-613 (Pubitemid 37162569)
-
(2003)
Lancet Neurology
, vol.2
, Issue.10
, pp. 605-613
-
-
Blennow, K.1
Hampel, H.2
-
26
-
-
47849108966
-
Quantitative analysis of transthyretin, tau and amyloid-β in patients with dementia
-
Gloeckner S F, Meyne F, Wagner F, et al. Quantitative analysis of transthyretin, tau and amyloid-beta in patients with dementia. J Alzheimers Dis, 2008, 14(1): 17-25 (Pubitemid 352039015)
-
(2008)
Journal of Alzheimer's Disease
, vol.14
, Issue.1
, pp. 17-25
-
-
Gloeckner, S.F.1
Meyne, F.2
Wagner, F.3
Heinemann, U.4
Krasnianski, A.5
Meissner, B.6
Zerr, I.7
-
27
-
-
49449108546
-
Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease
-
Zetterberg H, Andreasson U, Hansson O, et al. Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease. Arch Neurol, 2008, 65( 8): 1102-1107
-
(2008)
Arch Neurol
, vol.65
, Issue.8
, pp. 1102-1107
-
-
Zetterberg, H.1
Andreasson, U.2
Hansson, O.3
-
28
-
-
34249942064
-
Levels of β-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment
-
DOI 10.1001/archpsyc.64.6.718
-
Zhong Z, Ewers M, Teipel S, et al. Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment. Arch Gen Psychiatry, 2007, 64(6): 718-726 (Pubitemid 46878672)
-
(2007)
Archives of General Psychiatry
, vol.64
, Issue.6
, pp. 718-726
-
-
Zhong, Z.1
Ewers, M.2
Teipel, S.3
Burger, K.4
Wallin, A.5
Blennow, K.6
He, P.7
McAllister, C.8
Hampel, H.9
Shen, Y.10
-
29
-
-
44949221768
-
Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease
-
Ewers M, Zhong Z, Burger K, et al. Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease. Brain, 2008, 131( Pt 5): 1252-1258
-
(2008)
Brain
, vol.131
, Issue.PART 5
, pp. 1252-1258
-
-
Ewers, M.1
Zhong, Z.2
Burger, K.3
-
30
-
-
80053484102
-
Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease
-
Jiang H, Hampel H, Prvulovic D, et al. Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease. Mol Neurodegener, 2011, 6( 1): 69
-
(2011)
Mol Neurodegener
, vol.6
, Issue.1
, pp. 69
-
-
Jiang, H.1
Hampel, H.2
Prvulovic, D.3
-
31
-
-
77951962298
-
Recent progress in neurodegenerative disorder research in China
-
Zhou J W. Recent progress in neurodegenerative disorder research in China. Sci China Life Sci, 2010, 53( 3): 348-355
-
(2010)
Sci China Life Sci
, vol.53
, Issue.3
, pp. 348-355
-
-
Zhou, J.W.1
-
32
-
-
78449288804
-
Promoter polymorphisms which regulate ADAM9 transcription are protective against sporadic Alzheimer's disease
-
Cong L, Jia J. Promoter polymorphisms which regulate ADAM9 transcription are protective against sporadic Alzheimer's disease. Neurobiol Aging, 2011, 32( 1): 54-62
-
(2011)
Neurobiol Aging
, vol.32
, Issue.1
, pp. 54-62
-
-
Cong, L.1
Jia, J.2
-
33
-
-
84879265725
-
Accumulated hippocampal formaldehyde induces age-dependent memory decline
-
DOI: 10.1007/s11357-012-9388-8
-
Tong Z Q, Han C S, Luo W H, et al. Accumulated hippocampal formaldehyde induces age-dependent memory decline. AGE ( 2012) DOI: 10.1007/s11357-012-9388-8
-
(2012)
AGE
-
-
Tong, Z.Q.1
Han, C.S.2
Luo, W.H.3
-
34
-
-
78650454215
-
Formaldehyde stress
-
He R Q, Lu J, Miao J Y. Formaldehyde stress. Sci China Life Sci, 2010, 53( 12): 1399-1404
-
(2010)
Sci China Life Sci
, vol.53
, Issue.12
, pp. 1399-1404
-
-
He, R.Q.1
Lu, J.2
Miao, J.Y.3
-
35
-
-
78449301205
-
Urine formaldehyde level is inversely correlated to mini mental state examination scores in senile dementia
-
Tong Z Q, Zhang J L, Luo W H, et al. Urine formaldehyde level is inversely correlated to mini mental state examination scores in senile dementia. Neurobiology of Aging, 2011, 32( 1): 31-41
-
(2011)
Neurobiology of Aging
, vol.32
, Issue.1
, pp. 31-41
-
-
Tong, Z.Q.1
Zhang, J.L.2
Luo, W.H.3
-
36
-
-
80051617317
-
A novel molecular mechanism for nitrated a-synuclein-induced cell death
-
Liu Y Y, Qiang M, Wei Y, et al. A novel molecular mechanism for nitrated a-synuclein-induced cell death. J Mol Cell Biol, 2011, 3( 4): 239-249
-
(2011)
J Mol Cell Biol
, vol.3
, Issue.4
, pp. 239-249
-
-
Liu, Y.Y.1
Qiang, M.2
Wei, Y.3
-
37
-
-
78650491895
-
-
Sajjad Haider Naqvi, Tau Sajjad Haider Naqvi, Wang W S, Miao J Y, et al. Prog Biochem Biophys, 2010, 37( 11): 1195-1203
-
(2010)
Prog Biochem Biophys
, vol.37
, Issue.11
, pp. 1195-1203
-
-
Naqvi, S.H.1
Naqvi, T.S.H.2
Wang, W.S.3
Miao, J.Y.4
-
38
-
-
77951961804
-
Progress in neural plasticity
-
Zhang X H, Poo M M. Progress in neural plasticity. Sci China Life Sci, 2010, 53( 3): 322-329
-
(2010)
Sci China Life Sci
, vol.53
, Issue.3
, pp. 322-329
-
-
Zhang, X.H.1
Poo, M.M.2
-
39
-
-
77951943759
-
Synapse formation and remodeling. Axon guidance and neuronal migration research in China
-
Luo Z G. Synapse formation and remodeling. Axon guidance and neuronal migration research in China. Sci China Life Sci, 2010, 53( 3): 315-321
-
(2010)
Sci China Life Sci
, vol.53
, Issue.3
, pp. 315-321
-
-
Luo, Z.G.1
-
40
-
-
76649089967
-
A meta-analysis of oxidative stress markers in schizophrenia
-
Zhang M, Zhao Z M, He L, et al. A meta-analysis of oxidative stress markers in schizophrenia. Sci China Life Sci, 2010, 53( 1): 112-124
-
(2010)
Sci China Life Sci
, vol.53
, Issue.1
, pp. 112-124
-
-
Zhang, M.1
Zhao, Z.M.2
He, L.3
-
41
-
-
77949282876
-
TLR4 signaling induced TLR2 expression in the process of mimic cerebral ischemia/reperfusion in vitro
-
Sun P, Zhang Q, Han J Y, et al. TLR4 signaling induced TLR2 expression in the process of mimic cerebral ischemia/reperfusion in vitro. Sci China Life Sci, 2010, 53( 1): 112-124
-
(2010)
Sci China Life Sci
, vol.53
, Issue.1
, pp. 112-124
-
-
Sun, P.1
Zhang, Q.2
Han, J.Y.3
-
42
-
-
77951966903
-
Ion channels in neuronal survival
-
Wang Y Z, Xu T L. Ion channels in neuronal survival. Sci China Life Sci, 2010, 53 ( 3): 342-347
-
(2010)
Sci China Life Sci
, vol.53
, Issue.3
, pp. 342-347
-
-
Wang, Y.Z.1
Xu, T.L.2
-
43
-
-
79959613455
-
Copper ions influence the toxicity of β-amyloid (1-42) in a concentration-dependent manner in a Caenorhabditis elegans model of Alzheimer's disease
-
Luo Y F, Zhang J, Liu N Q, et al. Copper ions influence the toxicity of β-amyloid (1-42) in a concentration-dependent manner in a Caenorhabditis elegans model of Alzheimer's disease. Sci China Life Sci, 2011, 54( 6): 527-534
-
(2011)
Sci China Life Sci
, vol.54
, Issue.6
, pp. 527-534
-
-
Luo, Y.F.1
Zhang, J.2
Liu, N.Q.3
-
44
-
-
77952079471
-
-
Liu L L, Sheng B Y, Gong K, et al. Prog Biochem Biophys, 2010, 37(2): 154-160
-
(2010)
Prog Biochem Biophys
, vol.37
, Issue.2
, pp. 154-160
-
-
Liu, L.L.1
Sheng, B.Y.2
Gong, K.3
|