Pharmacological inhibition of TLR4-NOX4 signal protects against neuronal death in transient focal ischemia

Scientific Reports

Volumn 2, Issue , 2012, Pages

  Suzuki, Yukiya ^a   Hattori, Kozo ^a   Hamanaka, Junya ^a   Murase, Tetsuji ^a   Egashira, Yusuke ^a,b   Mishiro, Keisuke ^a   Ishiguro, Mitsunori ^a,b   Tsuruma, Kazuhiro ^a   Hirose, Yoshinobu ^c   Tanaka, Hiroyuki ^a   Yoshimura, Shinichi ^b   Shimazawa, Masamitsu ^a   Inagaki, Naoki ^a   Nagasawa, Hideko ^a   Iwama, Toru ^b   Hara, Hideaki ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c GIFU UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ETHYL 6 (N (2 CHLORO 4 FLUOROPHENYL)SULFAMOYL)CYCLOHEX 1 ENE 1 CARBOXYLATE; ETHYL 6-(N-(2-CHLORO-4-FLUOROPHENYL)SULFAMOYL)CYCLOHEX-1-ENE-1-CARBOXYLATE; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NOX4 PROTEIN, HUMAN; NOX4 PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SULFONAMIDE; TLR4 PROTEIN, HUMAN; TLR4 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 4;

ADULT; ANIMAL; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CASE CONTROL STUDY; CELL DEATH; CEREBRAL ARTERY DISEASE; DISEASE MODEL; DRUG EFFECT; FEMALE; HUMAN; MALE; METABOLISM; MIDDLE AGED; MOUSE; MOUSE STRAIN; NERVE CELL; OXIDATIVE STRESS; PATHOLOGY; PATHOPHYSIOLOGY; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CASE-CONTROL STUDIES; CELL DEATH; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED STRAINS; MIDDLE AGED; NADPH OXIDASE; NEURONS; NF-KAPPA B; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; SIGNAL TRANSDUCTION; SULFONAMIDES; TOLL-LIKE RECEPTOR 4; YOUNG ADULT;

EID: 84870820048     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep00896     Document Type: Article

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