Blocking TLR2 in vivo protects against accumulation of inflammatory cells and neuronal injury in experimental stroke

Journal of Cerebral Blood Flow and Metabolism

Volumn 31, Issue 2, 2011, Pages 757-766

  Ziegler, Gina ^a   Freyer, Dorette ^b   Harhausen, Denise ^b   Khojasteh, Uldus ^b   Nietfeld, Wilfried ^a   Trendelenburg, George ^b  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

cerebral ischemia; MCAO; neuroprotection; stroke; TLR2; toll like receptor

Indexed keywords

CD11B ANTIGEN; RECEPTOR ANTIBODY; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 2 ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN NERVE CELL; BRAIN PROTECTION; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; ENCEPHALITIS; INFLAMMATORY CELL; MALE; MOUSE; NERVE CELL LESION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; STROKE; WILD TYPE;

ANIMALS; ANTIBODIES, BLOCKING; ANTIGENS, CD11B; BRAIN EDEMA; CELL COUNT; CELL DEATH; CEREBRAL INFARCTION; IMMUNOHISTOCHEMISTRY; INFARCTION, MIDDLE CEREBRAL ARTERY; INFLAMMATION; ISCHEMIC ATTACK, TRANSIENT; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; SIGNAL TRANSDUCTION; STROKE; TOLL-LIKE RECEPTOR 2;

EID: 79551633839     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2010.161     Document Type: Article

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