Informed Conditioning on Clinical Covariates Increases Power in Case-Control Association Studies

PLoS Genetics

Volumn 8, Issue 11, 2012, Pages

  Zaitlen, Noah ^a,b   Lindström, Sara ^a   Pasaniuc, Bogdan ^a,b   Cornelis, Marilyn ^c   Genovese, Giulio ^d   Pollack, Samuela ^a,b   Barton, Anne ^e   Bickeböller, Heike ^f   Bowden, Donald W ^g   Eyre, Steve ^e   Freedman, Barry I ^g   Friedman, David J ^d   Field, John K ^h   Groop, Leif ⁱ   Haugen, Aage ^j   Heinrich, Joachim ^k   Henderson, Brian E ^l   Hicks, Pamela J ^g   Hocking, Lynne J ^m   Kolonel, Laurence N ⁿ   Landi, Maria Teresa ^o   Langefeld, Carl D ^g   Le Marchand, Loic ⁿ   Meister, Michael ^p,q   Morgan, Ann W ^r   Raji, Olaide Y ^h   Risch, Angela ^q,s   Rosenberger, Albert ^f   Scherf, David ^s   Steer, Sophia ^t   Walshaw, Martin ^u   Waters, Kevin M ^l   Wilson, Anthony G ^v   Wordsworth, Paul ^w   Zienolddiny, Shanbeh ^j   Tchetgen, Eric Tchetgen ^a   Haiman, Christopher ^l   Hunter, David J ^a,b,c   Plenge, Robert M ^b,c   Worthington, Jane ^e   Christiani, David C ^a   Schaumberg, Debra A ^a,d,x   Chasman, Daniel I ^x   Altshuler, David ^b,d,y   Voight, Benjamin ^b,d,y   Kraft, Peter ^a,b   Patterson, Nick ^b   Price, Alkes L ^a,b   more..

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

^f UNIVERSITY OF GÖTTINGEN   (Germany)

^g WAKE FOREST SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF LIVERPOOL   (United Kingdom)

ⁱ LUND UNIVERSITY HOSPITAL   (Sweden)

^j NATIONAL INSTITUTE OF OCCUPATIONAL HEALTH   (Norway)

^k INSTITUTE OF EPIDEMIOLOGY   (Germany)

^l UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^m UNIVERSITY OF ABERDEEN   (United Kingdom)

ⁿ UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^o NATIONAL CANCER INSTITUTE   (United States)

^p UNIVERSITY OF HEIDELBERG   (Germany)

^q German Center for Lung Research   (Germany)

^r St James s University Hospital   (United Kingdom)

^s GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^t KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

^u LIVERPOOL HEART AND CHEST HOSPITAL   (United Kingdom)

^v UNIVERSITY OF SHEFFIELD   (United Kingdom)

^w NUFFIELD ORTHOPAEDIC CENTRE   (United Kingdom)

^x SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^y MASSACHUSETTS GENERAL HOSPITAL   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AGE; ARTICLE; BODY MASS; BREAST CANCER; CASE CONTROL STUDY; CONDITIONING; CONTROLLED STUDY; FALSE POSITIVE RESULT; GENE FREQUENCY; GENE IDENTIFICATION; GENE INTERACTION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; INFORMED CONDITIONING; KIDNEY FAILURE; LUNG CANCER; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; PREVALENCE; PROSTATE CANCER; RETINA MACULA AGE RELATED DEGENERATION; RHEUMATOID ARTHRITIS; RISK ASSESSMENT;

AGE FACTORS; BODY MASS INDEX; CASE-CONTROL STUDIES; CHROMOSOME MAPPING; FACTOR ANALYSIS, STATISTICAL; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LOGISTIC MODELS; MALE; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; SMOKING;

EID: 84870718214     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003032     Document Type: Article

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