-
1
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (2007).
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
2
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917-1920 (2007).
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
-
3
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
Vierbuchen T, Ostermeier A, Pang ZP et al. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463, 1035-1041 (2010).
-
(2010)
Nature
, vol.463
, pp. 1035-1041
-
-
Vierbuchen, T.1
Ostermeier, A.2
Pang, Z.P.3
-
4
-
-
84864628471
-
Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeatexpansion- associated phenotypes
-
The HD iPSC Consortium.
-
The HD iPSC Consortium. Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeatexpansion- associated phenotypes. Cell Stem Cell 11(2), 264-278 (2012).
-
(2012)
Cell Stem Cell
, vol.11
, Issue.2
, pp. 264-278
-
-
-
5
-
-
50149098605
-
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
-
Dimos JT, Rodolfa KT, Niakan KK et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 321, 1218-1221 (2008).
-
(2008)
Science
, vol.321
, pp. 1218-1221
-
-
Dimos, J.T.1
Rodolfa, K.T.2
Niakan, K.K.3
-
6
-
-
70249133666
-
Differentiation of spinal motor neurons from pluripotent human stem cells
-
Hu BY, Zhang SC. Differentiation of spinal motor neurons from pluripotent human stem cells. Nat. Protoc. 4, 1295-1304 (2009).
-
(2009)
Nat. Protoc.
, vol.4
, pp. 1295-1304
-
-
Hu, B.Y.1
Zhang, S.C.2
-
7
-
-
50549089957
-
Diseasespecific induced pluripotent stem cells
-
Park IH, Arora N, Huo H et al. Diseasespecific induced pluripotent stem cells. Cell 134, 877-886 (2008).
-
(2008)
Cell
, vol.134
, pp. 877-886
-
-
Park, I.H.1
Arora, N.2
Huo, H.3
-
8
-
-
84859569070
-
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
-
Bilican B, Serio A, Barmada SJ et al. Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proc. Natl Acad. Sci. USA 109(15), 5803-5808 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, Issue.15
, pp. 5803-5808
-
-
Bilican, B.1
Serio, A.2
Barmada, S.J.3
-
9
-
-
61349100729
-
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
Soldner F, Hockemeyer D, Beard C et al. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 136, 964-977 (2009).
-
(2009)
Cell
, vol.136
, pp. 964-977
-
-
Soldner, F.1
Hockemeyer, D.2
Beard, C.3
-
10
-
-
84860510280
-
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
-
Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I et al. Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease. EMBO Mol. Med. 4, 380-395 (2012).
-
(2012)
EMBO Mol. Med.
, vol.4
, pp. 380-395
-
-
Sanchez-Danes, A.1
Richaud-Patin, Y.2
Carballo-Carbajal, I.3
-
11
-
-
85027958626
-
Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
-
Ohi Y, Qin H, Hong C, Blouin L et al. Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells. Nat. Cell Biol. 13, 541-549 (2011).
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 541-549
-
-
Ohi, Y.1
Qin, H.2
Hong, C.3
Blouin, L.4
-
12
-
-
79551677421
-
Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines
-
Bock C, Kiskinis E, Verstappen G et al. Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. Cell 144, 439-452 (2011).
-
(2011)
Cell
, vol.144
, pp. 439-452
-
-
Bock, C.1
Kiskinis, E.2
Verstappen, G.3
-
13
-
-
79551665440
-
A functionally characterized test set of human induced pluripotent stem cells
-
Boulting GL, Kiskinis E, Croft GF et al. A functionally characterized test set of human induced pluripotent stem cells. Nat. Biotechnol. 29, 279-286 (2011).
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 279-286
-
-
Boulting, G.L.1
Kiskinis, E.2
Croft, G.F.3
-
14
-
-
79952258224
-
Somatic coding mutations in human induced pluripotent stem cells
-
Gore A, Li Z, Fung HL, Young JE et al. Somatic coding mutations in human induced pluripotent stem cells. Nature 471, 63-67 (2011).
-
(2011)
Nature
, vol.471
, pp. 63-67
-
-
Gore, A.1
Li, Z.2
Fung, H.L.3
Young, J.E.4
-
15
-
-
79952126043
-
Copy number variation and selection during reprogramming to pluripotency
-
Hussein SM, Batada NN, Vuoristo S et al. Copy number variation and selection during reprogramming to pluripotency. Nature 471, 58-62 (2011).
-
(2011)
Nature
, vol.471
, pp. 58-62
-
-
Hussein, S.M.1
Batada, N.N.2
Vuoristo, S.3
-
16
-
-
79960833952
-
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations
-
Soldner F, Laganiere J, Cheng AW et al. Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell 146, 318-331 (2011).
-
(2011)
Cell
, vol.146
, pp. 318-331
-
-
Soldner, F.1
Laganiere, J.2
Cheng, A.W.3
-
17
-
-
58949094552
-
Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells
-
Marion RM, Strati K, Li H, Tejera A et al. Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells. Cell Stem Cell 4, 141-154 (2009).
-
(2009)
Cell Stem Cell
, vol.4
, pp. 141-154
-
-
Marion, R.M.1
Strati, K.2
Li, H.3
Tejera, A.4
-
18
-
-
77955818622
-
Robust activation of the human but not mouse telomerase gene during the induction of pluripotency
-
Mathew R, Jia W, Sharma A et al. Robust activation of the human but not mouse telomerase gene during the induction of pluripotency. FASEB J. 24, 2702-2715 (2010).
-
(2010)
FASEB J.
, vol.24
, pp. 2702-2715
-
-
Mathew, R.1
Jia, W.2
Sharma, A.3
-
19
-
-
77449124088
-
Telomere dynamics in human cells reprogrammed to pluripotency
-
Suhr ST, Chang EA, Rodriguez RM et al. Telomere dynamics in human cells reprogrammed to pluripotency. PLoS ONE 4, e8124 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Suhr, S.T.1
Chang, E.A.2
Rodriguez, R.M.3
-
20
-
-
78651228154
-
Reprogramming of telomeric regions during the generation of human induced pluripotent stem cells and subsequent differentiation into fibroblast-like derivatives
-
Yehezkel S, Rebibo-Sabbah A, Segev Y et al. Reprogramming of telomeric regions during the generation of human induced pluripotent stem cells and subsequent differentiation into fibroblast-like derivatives. Epigenetics 6, 63-75 (2011).
-
(2011)
Epigenetics
, vol.6
, pp. 63-75
-
-
Yehezkel, S.1
Rebibo-Sabbah, A.2
Segev, Y.3
-
21
-
-
79952213482
-
Epigenetic and phenotypic profile of fibroblasts derived from induced pluripotent stem cells
-
Hewitt KJ, Shamis Y, Hayman RB et al. Epigenetic and phenotypic profile of fibroblasts derived from induced pluripotent stem cells. PLoS ONE 6, e17128 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Hewitt, K.J.1
Shamis, Y.2
Hayman, R.B.3
-
22
-
-
77955449906
-
Epigenetic memory in induced pluripotent stem cells
-
Kim K, Doi A, Wen B et al. Epigenetic memory in induced pluripotent stem cells. Nature 467, 285-290 (2010).
-
(2010)
Nature
, vol.467
, pp. 285-290
-
-
Kim, K.1
Doi, A.2
Wen, B.3
-
23
-
-
84856694078
-
Efficient differentiation of human embryonic and induced pluripotent stem cells into functional astrocytes
-
Emdad L, D'Souza SL, Kothari HP et al. Efficient differentiation of human embryonic and induced pluripotent stem cells into functional astrocytes. Stem Cells Dev. 21, 404-410 (2012).
-
(2012)
Stem Cells Dev.
, vol.21
, pp. 404-410
-
-
Emdad, L.1
D'Souza, S.L.2
Kothari, H.P.3
-
24
-
-
79958128131
-
Specification of transplantable astroglial subtypes from human pluripotent stem cells
-
Krencik R, Weick JP, Liu Y et al. Specification of transplantable astroglial subtypes from human pluripotent stem cells. Nat. Biotechnol. 29, 528-534 (2011).
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 528-534
-
-
Krencik, R.1
Weick, J.P.2
Liu, Y.3
-
25
-
-
80054798510
-
Directed differentiation of functional astroglial subtypes from human pluripotent stem cells
-
Krencik R, Zhang SC. Directed differentiation of functional astroglial subtypes from human pluripotent stem cells. Nat. Protoc. 6, 1710-1717 (2011).
-
(2011)
Nat. Protoc.
, vol.6
, pp. 1710-1717
-
-
Krencik, R.1
Zhang, S.C.2
-
26
-
-
84859555919
-
Direct conversion of fibroblasts into stably expandable neural stem cells
-
Thier M, Worsdorfer P, Lakes YB et al. Direct conversion of fibroblasts into stably expandable neural stem cells. Cell Stem Cell 10, 473-479 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 473-479
-
-
Thier, M.1
Worsdorfer, P.2
Lakes, Y.B.3
-
27
-
-
77955908261
-
Generation of microglial cells from mouse embryonic stem cells
-
Beutner C, Roy K, Linnartz B et al. Generation of microglial cells from mouse embryonic stem cells. Nat. Protoc. 5, 1481-1494 (2010).
-
(2010)
Nat. Protoc.
, vol.5
, pp. 1481-1494
-
-
Beutner, C.1
Roy, K.2
Linnartz, B.3
-
28
-
-
79959951387
-
Direct conversion of human fibroblasts to dopaminergic neurons
-
Pfisterer U, Kirkeby A, Torper O et al. Direct conversion of human fibroblasts to dopaminergic neurons. Proc. Natl Acad. Sci USA 108, 10343-10348 (2011).
-
(2011)
Proc. Natl Acad. Sci USA
, vol.108
, pp. 10343-10348
-
-
Pfisterer, U.1
Kirkeby, A.2
Torper, O.3
-
29
-
-
79961173182
-
Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions
-
Ambasudhan R, Talantova M, Coleman R et al. Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions. Cell Stem Cell 9, 113-118 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 113-118
-
-
Ambasudhan, R.1
Talantova, M.2
Coleman, R.3
-
30
-
-
80051684096
-
MicroRNAmediated conversion of human fibroblasts to neurons
-
Yoo AS, Sun AX, Li L et al. MicroRNAmediated conversion of human fibroblasts to neurons. Nature 476, 228-231 (2011).
-
(2011)
Nature
, vol.476
, pp. 228-231
-
-
Yoo, A.S.1
Sun, A.X.2
Li, L.3
-
31
-
-
79961131135
-
Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons
-
Qiang L, Fujita R, Yamashita T et al. Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons. Cell 146, 359-371 (2011).
-
(2011)
Cell
, vol.146
, pp. 359-371
-
-
Qiang, L.1
Fujita, R.2
Yamashita, T.3
-
32
-
-
84855258568
-
The current status of neural grafting in the treatment of Huntington's disease. A review
-
Wijeyekoon R, Barker RA. The current status of neural grafting in the treatment of Huntington's disease. A review. Front. Integr. Neurosci. 5, 78 (2011).
-
(2011)
Front. Integr. Neurosci.
, vol.5
, Issue.78
-
-
Wijeyekoon, R.1
Barker, R.A.2
-
33
-
-
77957230012
-
Neural grafting in Parkinson's Disease. Problems and possibilities
-
Brundin P, Barker RA, Parmar M. Neural grafting in Parkinson's Disease. Problems and possibilities. Prog. Brain Res. 184, 265-294 (2010).
-
(2010)
Prog. Brain Res.
, vol.184
, pp. 265-294
-
-
Brundin, P.1
Barker, R.A.2
Parmar, M.3
-
34
-
-
0035826089
-
Transplantation of embryonic dopamine neurons for severe Parkinson's disease
-
Freed CR, Greene PE, Breeze RE et al. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N. Engl. J. Med. 344(10), 710-719 (2001).
-
(2001)
N. Engl. J. Med.
, vol.344
, Issue.10
, pp. 710-719
-
-
Freed, C.R.1
Greene, P.E.2
Breeze, R.E.3
-
35
-
-
0042837887
-
A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
-
Olanow CW, Goetz CG, Kordower JH et al. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Ann. Neurol. 54(3), 403-414 (2003).
-
(2003)
Ann. Neurol.
, vol.54
, Issue.3
, pp. 403-414
-
-
Olanow, C.W.1
Goetz, C.G.2
Kordower, J.H.3
-
36
-
-
77955617871
-
Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants
-
Politis M, Wu K, Loane C et al. Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants. Sci. Transl. Med. 2(38), 38ra46 (2010).
-
(2010)
Sci. Transl. Med.
, vol.2
, Issue.38
, pp. 38-46
-
-
Politis, M.1
Wu, K.2
Loane, C.3
-
37
-
-
84855895468
-
Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells
-
Sanchez-Danes A, Consiglio A, Richaud Y et al. Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells. Hum. Gene Ther. 23, 56-69 (2012).
-
(2012)
Hum. Gene Ther.
, vol.23
, pp. 56-69
-
-
Sanchez-Danes, A.1
Consiglio, A.2
Richaud, Y.3
-
38
-
-
79957795795
-
MiR-371-373 expression predicts neural differentiation propensity in human pluripotent stem cells
-
Kim H, Lee G, Granat Y et al. miR-371-373 expression predicts neural differentiation propensity in human pluripotent stem cells. Cell Stem Cell 8(6), 695-706 (2011).
-
(2011)
Cell Stem Cell
, vol.8
, Issue.6
, pp. 695-706
-
-
Kim, H.1
Lee, G.2
Granat, Y.3
-
39
-
-
33750706917
-
Functional engraftment of human ES cellderived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes
-
Roy NS, Cleren C, Singh SK et al. Functional engraftment of human ES cellderived dopaminergic neurons enriched by coculture with telomerase- immortalized midbrain astrocytes. Nat. Med. 12(11), 1259-1268 (2006).
-
(2006)
Nat. Med.
, vol.12
, Issue.11
, pp. 1259-1268
-
-
Roy, N.S.1
Cleren, C.2
Singh, S.K.3
-
40
-
-
84355166561
-
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease
-
Kriks S, Shim JW, Piao J et al. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 480, 547-551 (2011).
-
(2011)
Nature
, vol.480
, pp. 547-551
-
-
Kriks, S.1
Shim, J.W.2
Piao, J.3
-
41
-
-
77957670482
-
Differentiated parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in parkinsonian rats
-
Hargus G, Cooper O, Deleidi M et al. Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats. Proc. Natl Acad. Sci. USA 107, 15921-15926 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 15921-15926
-
-
Hargus, G.1
Cooper, O.2
Deleidi, M.3
-
42
-
-
79957807595
-
Immunogenicity of induced pluripotent stem cells
-
Zhao T, Zhang ZN, Rong Z, Xu Y. Immunogenicity of induced pluripotent stem cells. Nature 474, 212-215 (2011).
-
(2011)
Nature
, vol.474
, pp. 212-215
-
-
Zhao, T.1
Zhang, Z.N.2
Rong, Z.3
Xu, Y.4
-
43
-
-
80755129026
-
Functional integration of dopaminergic neurons directly converted from mouse fibroblasts
-
Kim J, Su SC, Wang H et al. Functional integration of dopaminergic neurons directly converted from mouse fibroblasts. Cell Stem Cell 9, 413-419 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 413-419
-
-
Kim, J.1
Su, S.C.2
Wang, H.3
-
44
-
-
84856612240
-
Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells
-
Liu X, Li F, Stubblefield EA et al. Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells. Cell Res. 22, 321-332 (2012).
-
(2012)
Cell Res.
, vol.22
, pp. 321-332
-
-
Liu, X.1
Li, F.2
Stubblefield, E.A.3
-
45
-
-
84870067243
-
Rett syndrome induced pluripotent stem cellderived neurons reveal novel neurophysiological alterations
-
doi: 10.1038/mp.2011.180 Epub ahead of print).
-
Farra N, Zhang WB, Pasceri P et al. Rett syndrome induced pluripotent stem cellderived neurons reveal novel neurophysiological alterations. Mol. Psychiatry doi: 10.1038/mp.2011.180 (2012) (Epub ahead of print).
-
(2012)
Mol. Psychiatry
-
-
Farra, N.1
Zhang, W.B.2
Pasceri, P.3
-
46
-
-
80052784383
-
Development of patient-specific neurons in schizophrenia using induced pluripotent stem cells
-
Pedrosa E, Sandler V, Shah A et al. Development of patient-specific neurons in schizophrenia using induced pluripotent stem cells. J. Neurogenet. 25, 88-103 (2011).
-
(2011)
J. Neurogenet.
, vol.25
, pp. 88-103
-
-
Pedrosa, E.1
Sandler, V.2
Shah, A.3
-
47
-
-
84860232921
-
Derivation of autism spectrum disorder-specific induced pluripotent stem cells from peripheral blood mononuclear cells
-
DeRosa BA, Van Baaren JM, Dubey GK et al. Derivation of autism spectrum disorder-specific induced pluripotent stem cells from peripheral blood mononuclear cells. Neurosci. Lett. 516, 9-14 (2012).
-
(2012)
Neurosci. Lett.
, vol.516
, pp. 9-14
-
-
Derosa, B.A.1
Van Baaren, J.M.2
Dubey, G.K.3
|