메뉴 건너뛰기




Volumn 8, Issue 11, 2012, Pages

A Dominantly Acting Murine Allele of Mcm4 Causes Chromosomal Abnormalities and Promotes Tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MINICHROMOSOME MAINTENANCE PROTEIN 2; MINICHROMOSOME MAINTENANCE PROTEIN 4; MINICHROMOSOME MAINTENANCE PROTEIN 7; NOTCH1 RECEPTOR;

EID: 84870701350     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003034     Document Type: Article
Times cited : (33)

References (46)
  • 1
    • 71449107031 scopus 로고    scopus 로고
    • The Mcm complex: unwinding the mechanism of a replicative helicase
    • Bochman ML, Schwacha A, (2009) The Mcm complex: unwinding the mechanism of a replicative helicase. Microbiol Mol Biol Rev 73: 652-683.
    • (2009) Microbiol Mol Biol Rev , vol.73 , pp. 652-683
    • Bochman, M.L.1    Schwacha, A.2
  • 3
    • 33845877445 scopus 로고    scopus 로고
    • A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice
    • Shima N, Alcaraz A, Liachko I, Buske TR, Andrews CA, et al. (2007) A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice. Nature genetics 39: 93-98.
    • (2007) Nature Genetics , vol.39 , pp. 93-98
    • Shima, N.1    Alcaraz, A.2    Liachko, I.3    Buske, T.R.4    Andrews, C.A.5
  • 4
    • 78049417542 scopus 로고    scopus 로고
    • Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress
    • Chuang CH, Wallace MD, Abratte C, Southard T, Schimenti JC, (2010) Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress. PLoS Genet 6.
    • (2010) PLoS Genet , vol.6
    • Chuang, C.H.1    Wallace, M.D.2    Abratte, C.3    Southard, T.4    Schimenti, J.C.5
  • 5
    • 37349025510 scopus 로고    scopus 로고
    • Reduced Mcm2 expression results in severe stem/progenitor cell deficiency and cancer
    • Pruitt SC, Bailey KJ, Freeland A, (2007) Reduced Mcm2 expression results in severe stem/progenitor cell deficiency and cancer. Stem Cells 25: 3121-3132.
    • (2007) Stem Cells , vol.25 , pp. 3121-3132
    • Pruitt, S.C.1    Bailey, K.J.2    Freeland, A.3
  • 6
    • 79951970806 scopus 로고    scopus 로고
    • Stalled Fork Rescue via Dormant Replication Origins in Unchallenged S Phase Promotes Proper Chromosome Segregation and Tumor Suppression
    • Kawabata T, Luebben SW, Yamaguchi S, Ilves I, Matise I, et al. (2011) Stalled Fork Rescue via Dormant Replication Origins in Unchallenged S Phase Promotes Proper Chromosome Segregation and Tumor Suppression. Mol Cell 41: 543-553.
    • (2011) Mol Cell , vol.41 , pp. 543-553
    • Kawabata, T.1    Luebben, S.W.2    Yamaguchi, S.3    Ilves, I.4    Matise, I.5
  • 7
    • 77954084683 scopus 로고    scopus 로고
    • DNA damage response and tumorigenesis in Mcm2-deficient mice
    • Kunnev D, Rusiniak ME, Kudla A, Freeland A, Cady GK, et al. (2010) DNA damage response and tumorigenesis in Mcm2-deficient mice. Oncogene 29: 3630-3638.
    • (2010) Oncogene , vol.29 , pp. 3630-3638
    • Kunnev, D.1    Rusiniak, M.E.2    Kudla, A.3    Freeland, A.4    Cady, G.K.5
  • 8
    • 0042452295 scopus 로고    scopus 로고
    • Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5
    • Roberts CW, Leroux MM, Fleming MD, Orkin SH, (2002) Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5. Cancer Cell 2: 415-425.
    • (2002) Cancer Cell , vol.2 , pp. 415-425
    • Roberts, C.W.1    Leroux, M.M.2    Fleming, M.D.3    Orkin, S.H.4
  • 9
    • 0035930346 scopus 로고    scopus 로고
    • Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication
    • Schwacha A, Bell SP, (2001) Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication. Mol Cell 8: 1093-1104.
    • (2001) Mol Cell , vol.8 , pp. 1093-1104
    • Schwacha, A.1    Bell, S.P.2
  • 11
    • 0033681301 scopus 로고    scopus 로고
    • Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes
    • Deftos ML, Huang E, Ojala EW, Forbush KA, Bevan MJ, (2000) Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes. Immunity 13: 73-84.
    • (2000) Immunity , vol.13 , pp. 73-84
    • Deftos, M.L.1    Huang, E.2    Ojala, E.W.3    Forbush, K.A.4    Bevan, M.J.5
  • 12
    • 0042834334 scopus 로고    scopus 로고
    • Notch signaling augments T cell responsiveness by enhancing CD25 expression
    • Adler SH, Chiffoleau E, Xu L, Dalton NM, Burg JM, et al. (2003) Notch signaling augments T cell responsiveness by enhancing CD25 expression. Journal of immunology 171: 2896-2903.
    • (2003) Journal of Immunology , vol.171 , pp. 2896-2903
    • Adler, S.H.1    Chiffoleau, E.2    Xu, L.3    Dalton, N.M.4    Burg, J.M.5
  • 13
    • 0034726709 scopus 로고    scopus 로고
    • Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes
    • Maier MM, Gessler M, (2000) Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes. Biochemical and biophysical research communications 275: 652-660.
    • (2000) Biochemical and Biophysical Research Communications , vol.275 , pp. 652-660
    • Maier, M.M.1    Gessler, M.2
  • 14
    • 5044225888 scopus 로고    scopus 로고
    • Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
    • Weng AP, Ferrando AA, Lee W, Morris JPt, Silverman LB, et al. (2004) Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306: 269-271.
    • (2004) Science , vol.306 , pp. 269-271
    • Weng, A.P.1    Ferrando, A.A.2    Lee, W.3    Morris, J.P.4    Silverman, L.B.5
  • 16
    • 78650335900 scopus 로고    scopus 로고
    • Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1
    • Ashworth TD, Pear WS, Chiang MY, Blacklow SC, Mastio J, et al. (2010) Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1. Blood 116: 5455-5464.
    • (2010) Blood , vol.116 , pp. 5455-5464
    • Ashworth, T.D.1    Pear, W.S.2    Chiang, M.Y.3    Blacklow, S.C.4    Mastio, J.5
  • 17
    • 78650379575 scopus 로고    scopus 로고
    • Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL
    • Jeannet R, Mastio J, Macias-Garcia A, Oravecz A, Ashworth T, et al. (2010) Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Blood 116: 5443-5454.
    • (2010) Blood , vol.116 , pp. 5443-5454
    • Jeannet, R.1    Mastio, J.2    Macias-Garcia, A.3    Oravecz, A.4    Ashworth, T.5
  • 18
    • 79958023043 scopus 로고    scopus 로고
    • MCM Proteins Are Negative Regulators of Hypoxia-Inducible Factor 1
    • Hubbi ME, Luo W, Baek JH, Semenza GL, (2011) MCM Proteins Are Negative Regulators of Hypoxia-Inducible Factor 1. Molecular cell 42: 700-712.
    • (2011) Molecular Cell , vol.42 , pp. 700-712
    • Hubbi, M.E.1    Luo, W.2    Baek, J.H.3    Semenza, G.L.4
  • 20
    • 0032729099 scopus 로고    scopus 로고
    • Cloning of a novel MHC-encoded serine peptidase highly expressed by cortical epithelial cells of the thymus
    • Bowlus CL, Ahn J, Chu T, Gruen JR, (1999) Cloning of a novel MHC-encoded serine peptidase highly expressed by cortical epithelial cells of the thymus. Cellular immunology 196: 80-86.
    • (1999) Cellular Immunology , vol.196 , pp. 80-86
    • Bowlus, C.L.1    Ahn, J.2    Chu, T.3    Gruen, J.R.4
  • 21
    • 84870695426 scopus 로고    scopus 로고
    • Mcm2 deficiency results in short deletions allowing high resolution identification of genes contributing to lymphoblastic lymphoma
    • Rusiniak ME, Kunnev D, Freeland A, Cady GK, Pruitt SC, (2011) Mcm2 deficiency results in short deletions allowing high resolution identification of genes contributing to lymphoblastic lymphoma. Oncogene.
    • (2011) Oncogene
    • Rusiniak, M.E.1    Kunnev, D.2    Freeland, A.3    Cady, G.K.4    Pruitt, S.C.5
  • 22
    • 58149308526 scopus 로고    scopus 로고
    • Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1
    • Li X, Gounari F, Protopopov A, Khazaie K, von Boehmer H, (2008) Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1. J Exp Med 205: 2851-2861.
    • (2008) J Exp Med , vol.205 , pp. 2851-2861
    • Li, X.1    Gounari, F.2    Protopopov, A.3    Khazaie, K.4    von Boehmer, H.5
  • 23
    • 68049140918 scopus 로고    scopus 로고
    • Aneuploidy and improved growth are coincident but not causal in a yeast cancer model
    • Li XC, Schimenti JC, Tye BK, (2009) Aneuploidy and improved growth are coincident but not causal in a yeast cancer model. PLoS biology 7: e1000161.
    • (2009) PLoS Biology , vol.7
    • Li, X.C.1    Schimenti, J.C.2    Tye, B.K.3
  • 24
    • 78049431126 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate
    • Bochman ML, Schwacha A, (2010) The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'. Nucleic Acids Res 38: 6078-6088.
    • (2010) Nucleic Acids Res , vol.38 , pp. 6078-6088
    • Bochman, M.L.1    Schwacha, A.2
  • 25
    • 52649096993 scopus 로고    scopus 로고
    • Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability
    • Bochman ML, Bell SP, Schwacha A, (2008) Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability. Mol Cell Biol 28: 5865-5873.
    • (2008) Mol Cell Biol , vol.28 , pp. 5865-5873
    • Bochman, M.L.1    Bell, S.P.2    Schwacha, A.3
  • 26
    • 1642325936 scopus 로고    scopus 로고
    • Evolutionary history and higher order classification of AAA+ ATPases
    • Iyer LM, Leipe DD, Koonin EV, Aravind L, (2004) Evolutionary history and higher order classification of AAA+ ATPases. J Struct Biol 146: 11-31.
    • (2004) J Struct Biol , vol.146 , pp. 11-31
    • Iyer, L.M.1    Leipe, D.D.2    Koonin, E.V.3    Aravind, L.4
  • 27
    • 77749286992 scopus 로고    scopus 로고
    • MCM proteins as diagnostic and prognostic tumor markers in the clinical setting
    • Giaginis C, Vgenopoulou S, Vielh P, Theocharis S, (2010) MCM proteins as diagnostic and prognostic tumor markers in the clinical setting. Histol Histopathol 25: 351-370.
    • (2010) Histol Histopathol , vol.25 , pp. 351-370
    • Giaginis, C.1    Vgenopoulou, S.2    Vielh, P.3    Theocharis, S.4
  • 28
    • 77957796717 scopus 로고    scopus 로고
    • Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion
    • Lau KM, Chan QK, Pang JC, Li KK, Yeung WW, et al. (2010) Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion. Oncogene 29: 5475-5489.
    • (2010) Oncogene , vol.29 , pp. 5475-5489
    • Lau, K.M.1    Chan, Q.K.2    Pang, J.C.3    Li, K.K.4    Yeung, W.W.5
  • 29
    • 33745795112 scopus 로고    scopus 로고
    • Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis
    • Honeycutt KA, Chen Z, Koster MI, Miers M, Nuchtern J, et al. (2006) Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis. Oncogene 25: 4027-4032.
    • (2006) Oncogene , vol.25 , pp. 4027-4032
    • Honeycutt, K.A.1    Chen, Z.2    Koster, M.I.3    Miers, M.4    Nuchtern, J.5
  • 30
    • 77953948708 scopus 로고    scopus 로고
    • Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation
    • Poliseno L, Salmena L, Riccardi L, Fornari A, Song MS, et al. (2010) Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Science signaling 3: ra29.
    • (2010) Science Signaling , vol.3
    • Poliseno, L.1    Salmena, L.2    Riccardi, L.3    Fornari, A.4    Song, M.S.5
  • 31
    • 78651330430 scopus 로고    scopus 로고
    • COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
    • Forbes SA, Bindal N, Bamford S, Cole C, Kok CY, et al. (2011) COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic acids research 39: D945-950.
    • (2011) Nucleic Acids Research , vol.39
    • Forbes, S.A.1    Bindal, N.2    Bamford, S.3    Cole, C.4    Kok, C.Y.5
  • 32
    • 22444431606 scopus 로고    scopus 로고
    • Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system
    • Dupuy AJ, Akagi K, Largaespada DA, Copeland NG, Jenkins NA, (2005) Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system. Nature 436: 221-226.
    • (2005) Nature , vol.436 , pp. 221-226
    • Dupuy, A.J.1    Akagi, K.2    Largaespada, D.A.3    Copeland, N.G.4    Jenkins, N.A.5
  • 33
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • Li H, Durbin R, (2009) Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25: 1754-1760.
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 34
    • 77956295988 scopus 로고    scopus 로고
    • The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data
    • McKenna A, Hanna M, Banks E, Sivachenko A, Cibulskis K, et al. (2010) The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome research 20: 1297-1303.
    • (2010) Genome Research , vol.20 , pp. 1297-1303
    • McKenna, A.1    Hanna, M.2    Banks, E.3    Sivachenko, A.4    Cibulskis, K.5
  • 35
    • 80052851950 scopus 로고    scopus 로고
    • Mouse genomic variation and its effect on phenotypes and gene regulation
    • Keane TM, Goodstadt L, Danecek P, White MA, Wong K, et al. (2011) Mouse genomic variation and its effect on phenotypes and gene regulation. Nature 477: 289-294.
    • (2011) Nature , vol.477 , pp. 289-294
    • Keane, T.M.1    Goodstadt, L.2    Danecek, P.3    White, M.A.4    Wong, K.5
  • 37
    • 1542609301 scopus 로고    scopus 로고
    • Forward genetic screens for meiotic and mitotic recombination-defective mutants in mice
    • Reinholdt L, Ashley T, Schimenti J, Shima N, (2004) Forward genetic screens for meiotic and mitotic recombination-defective mutants in mice. Methods in molecular biology 262: 87-107.
    • (2004) Methods in Molecular Biology , vol.262 , pp. 87-107
    • Reinholdt, L.1    Ashley, T.2    Schimenti, J.3    Shima, N.4
  • 38
    • 24944534978 scopus 로고    scopus 로고
    • Real-time PCR for mRNA quantitation
    • Wong ML, Medrano JF, (2005) Real-time PCR for mRNA quantitation. Bio Techniques 39: 75-85.
    • (2005) Bio Techniques , vol.39 , pp. 75-85
    • Wong, M.L.1    Medrano, J.F.2
  • 39
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, et al. (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4: 249-264.
    • (2003) Biostatistics , vol.4 , pp. 249-264
    • Irizarry, R.A.1    Hobbs, B.2    Collin, F.3    Beazer-Barclay, Y.D.4    Antonellis, K.J.5
  • 40
    • 38649143214 scopus 로고    scopus 로고
    • A comparison of Affymetrix gene expression arrays
    • Robinson MD, Speed TP, (2007) A comparison of Affymetrix gene expression arrays. BMC bioinformatics 8: 449.
    • (2007) BMC Bioinformatics , vol.8 , pp. 449
    • Robinson, M.D.1    Speed, T.P.2
  • 41
    • 0034923013 scopus 로고    scopus 로고
    • On differential variability of expression ratios: improving statistical inference about gene expression changes from microarray data
    • Newton MA, Kendziorski CM, Richmond CS, Blattner FR, Tsui KW, (2001) On differential variability of expression ratios: improving statistical inference about gene expression changes from microarray data. J Comput Biol 8: 37-52.
    • (2001) J Comput Biol , vol.8 , pp. 37-52
    • Newton, M.A.1    Kendziorski, C.M.2    Richmond, C.S.3    Blattner, F.R.4    Tsui, K.W.5
  • 42
    • 0346888587 scopus 로고    scopus 로고
    • On parametric empirical Bayes methods for comparing multiple groups using replicated gene expression profiles
    • Kendziorski CM, Newton MA, Lan H, Gould MN, (2003) On parametric empirical Bayes methods for comparing multiple groups using replicated gene expression profiles. Stat Med 22: 3899-3914.
    • (2003) Stat Med , vol.22 , pp. 3899-3914
    • Kendziorski, C.M.1    Newton, M.A.2    Lan, H.3    Gould, M.N.4
  • 43
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey JD, Tibshirani R, (2003) Statistical significance for genomewide studies. Proc Natl Acad Sci U S A 100: 9440-9445.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 46
    • 84870716112 scopus 로고    scopus 로고
    • The PyMOL Molecular Graphics System Version 1.5.0.4 ed: Schrödinger, LLC
    • The PyMOL Molecular Graphics System Version 1.5.0.4 ed: Schrödinger, LLC.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.