메뉴 건너뛰기




Volumn 40, Issue 2, 2010, Pages 530-538

Spatial (Tbata) expression in mature medullary thymic epithelial cells

Author keywords

Aire; Epithelial cells; Spatial; Thymic ontogeny

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; ISOPROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; STROMAL PROTEIN ASSOCIATED WITH THYMII AND LYMPH NODE; UNCLASSIFIED DRUG;

EID: 75149113242     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200939605     Document Type: Article
Times cited : (9)

References (42)
  • 1
    • 0035496231 scopus 로고    scopus 로고
    • Lymphostromal interactions in thymic development and function
    • Anderson, G. and Jenkinson, E. J., Lymphostromal interactions in thymic development and function. Nat. Rev. Immunol. 2001. 1: 31-40.
    • (2001) Nat. Rev. Immunol , vol.1 , pp. 31-40
    • Anderson, G.1    Jenkinson, E.J.2
  • 4
    • 0037375743 scopus 로고    scopus 로고
    • A developmental look at thymus organogenesis: Where do the non- hematopoietic cells in the thymus come from?
    • Manley, N. R. and Blackburn, C. C., A developmental look at thymus organogenesis: where do the non- hematopoietic cells in the thymus come from? Curr. Opin. Immunol. 2003. 15: 225-232.
    • (2003) Curr. Opin. Immunol , vol.15 , pp. 225-232
    • Manley, N.R.1    Blackburn, C.C.2
  • 6
    • 0030742876 scopus 로고    scopus 로고
    • Immuno-electron microscopy of the thymic epithelial microenvironment
    • Von Gaudecker, B., Kendall, M. D. and Ritter, M. A., Immuno-electron microscopy of the thymic epithelial microenvironment. Microsc. Res. Tech. 1997. 38: 237-249.
    • (1997) Microsc. Res. Tech , vol.38 , pp. 237-249
    • Von Gaudecker, B.1    Kendall, M.D.2    Ritter, M.A.3
  • 7
    • 0032785117 scopus 로고    scopus 로고
    • Differential gene expression in CD3epsilon-and RAG1-deficient thymuses: Definition of a set of genes potentially involved in thymocyte maturation
    • Carrier, A., Nguyen, C., Victorero, G., Granjeaud, S., Rocha, D., Bernard, K., Miazek, A. et al., Differential gene expression in CD3epsilon-and RAG1-deficient thymuses: definition of a set of genes potentially involved in thymocyte maturation. Immunogenetics 1999. 50: 255-270.
    • (1999) Immunogenetics , vol.50 , pp. 255-270
    • Carrier, A.1    Nguyen, C.2    Victorero, G.3    Granjeaud, S.4    Rocha, D.5    Bernard, K.6    Miazek, A.7
  • 8
    • 9444275932 scopus 로고    scopus 로고
    • Genomic organization and the tissue distribution of alternatively spliced isoforms of the mouse Spatial gene
    • Irla, M., Puthier, D., Granjeaud, S., Saade, M., Victorero, G., Mattei, M. G. and Nguyen, C., Genomic organization and the tissue distribution of alternatively spliced isoforms of the mouse Spatial gene. BMC Genomics 2004. 5: 41-51.
    • (2004) BMC Genomics , vol.5 , pp. 41-51
    • Irla, M.1    Puthier, D.2    Granjeaud, S.3    Saade, M.4    Victorero, G.5    Mattei, M.G.6    Nguyen, C.7
  • 10
    • 33846837241 scopus 로고    scopus 로고
    • Dynamic distribution of Spatial during mouse spermatogenesis and its interaction with the kinesin KIF17b
    • Saade, M., Irla, M., Govin, J., Victorero, G., Samson, M. and Nguyen, C., Dynamic distribution of Spatial during mouse spermatogenesis and its interaction with the kinesin KIF17b. Exp. Cell Res. 2007. 313: 614-626.
    • (2007) Exp. Cell Res , vol.313 , pp. 614-626
    • Saade, M.1    Irla, M.2    Govin, J.3    Victorero, G.4    Samson, M.5    Nguyen, C.6
  • 11
    • 36049036568 scopus 로고    scopus 로고
    • Neuronal distribution of spatial in the developing cerebellum and hippocampus and its somatodendritic association with the kinesin motor KIF17
    • Irla, M., Saade, M., Fernandez, C., Chasson, L., Victorero, G., Dahmane, N., Chazal, G. and Nguyen, C., Neuronal distribution of spatial in the developing cerebellum and hippocampus and its somatodendritic association with the kinesin motor KIF17. Exp. Cell Res. 2007. 313: 4107-4119.
    • (2007) Exp. Cell Res , vol.313 , pp. 4107-4119
    • Irla, M.1    Saade, M.2    Fernandez, C.3    Chasson, L.4    Victorero, G.5    Dahmane, N.6    Chazal, G.7    Nguyen, C.8
  • 12
    • 0037459061 scopus 로고    scopus 로고
    • The molecular motor toolbox for intracellular transport
    • Vale, R. D., The molecular motor toolbox for intracellular transport. Cell 2003. 112: 467-480.
    • (2003) Cell , vol.112 , pp. 467-480
    • Vale, R.D.1
  • 13
    • 0034252202 scopus 로고    scopus 로고
    • Spatial, a gene expressed in thymic stromal cells, depends on three-dimensional thymus organization for its expression
    • Flomerfelt, F. A., Kim,M. G. and Schwartz, R. H., Spatial, a gene expressed in thymic stromal cells, depends on three-dimensional thymus organization for its expression. Genes Immun. 2000. 1: 391-401.
    • (2000) Genes Immun , vol.1 , pp. 391-401
    • Flomerfelt, F.A.1    Kim, M.G.2    Schwartz, R.H.3
  • 14
    • 0035005477 scopus 로고    scopus 로고
    • Gcm2 and Foxn1 mark early parathyroid- and thymus-specific domains in the developing third pharyngeal pouch
    • Gordon, J., Bennett, A. R., Blackburn, C. C. and Manley, N. R., Gcm2 and Foxn1 mark early parathyroid- and thymus-specific domains in the developing third pharyngeal pouch. Mech. Dev. 2001. 103: 141-143.
    • (2001) Mech. Dev , vol.103 , pp. 141-143
    • Gordon, J.1    Bennett, A.R.2    Blackburn, C.C.3    Manley, N.R.4
  • 17
    • 0036063262 scopus 로고    scopus 로고
    • Identification and characterization of thymic epithelial progenitor cells
    • Bennett, A. R., Farley, A., Blair, N. F., Gordon, J., Sharp, L. and Blackburn, C. C., Identification and characterization of thymic epithelial progenitor cells. Immunity 2002. 16: 803-814.
    • (2002) Immunity , vol.16 , pp. 803-814
    • Bennett, A.R.1    Farley, A.2    Blair, N.F.3    Gordon, J.4    Sharp, L.5    Blackburn, C.C.6
  • 18
    • 0036305567 scopus 로고    scopus 로고
    • Generation of a complete thymic microenvironment by MTS24(+) thymic epithelial cells
    • Gill, J., Malin, M., Holländer, G. A. and Boyd, R., Generation of a complete thymic microenvironment by MTS24(+) thymic epithelial cells. Nat. Immunol. 2002. 3: 635-642.
    • (2002) Nat. Immunol , vol.3 , pp. 635-642
    • Gill, J.1    Malin, M.2    Holländer, G.A.3    Boyd, R.4
  • 20
    • 0033753252 scopus 로고    scopus 로고
    • Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation
    • Manley, N. R., Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation. Semin. Immunol. 2000. 12: 421-428.
    • (2000) Semin. Immunol , vol.12 , pp. 421-428
    • Manley, N.R.1
  • 21
    • 0037105620 scopus 로고    scopus 로고
    • Cutting edge: Thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus
    • Klug, D. B., Carter, C., Gimenez-Conti, I. B. and Richie, E. R., Cutting edge: thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus. J. Immunol. 2002. 169: 2842-2845.
    • (2002) J. Immunol , vol.169 , pp. 2842-2845
    • Klug, D.B.1    Carter, C.2    Gimenez-Conti, I.B.3    Richie, E.R.4
  • 24
    • 0026485046 scopus 로고
    • Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages
    • Mombaerts, P., Clarke, A. R., Rudnicki, M. A., Iacomini, J., Itohara, S., Lafaille, J. J., Wang, L. et al., Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages. Nature 1992. 360: 225-231.
    • (1992) Nature , vol.360 , pp. 225-231
    • Mombaerts, P.1    Clarke, A.R.2    Rudnicki, M.A.3    Iacomini, J.4    Itohara, S.5    Lafaille, J.J.6    Wang, L.7
  • 25
    • 33646165128 scopus 로고    scopus 로고
    • A central role for central tolerance
    • Kyewski, B. and Klein, L., A central role for central tolerance. Annu. Rev. Immunol. 2006. 24: 571-606.
    • (2006) Annu. Rev. Immunol , vol.24 , pp. 571-606
    • Kyewski, B.1    Klein, L.2
  • 26
    • 22344434168 scopus 로고    scopus 로고
    • Contrasting models of promiscuous gene expression by thymic epithelium
    • Gillard, G. O. and Farr, A. G., Contrasting models of promiscuous gene expression by thymic epithelium. J. Exp. Med. 2005. 202: 15-19.
    • (2005) J. Exp. Med , vol.202 , pp. 15-19
    • Gillard, G.O.1    Farr, A.G.2
  • 27
    • 67549118180 scopus 로고    scopus 로고
    • Mathis, D. and Benoist, C., Aire. Annu. Rev. Immunol. 2009. 27: 287-312.
    • Mathis, D. and Benoist, C., Aire. Annu. Rev. Immunol. 2009. 27: 287-312.
  • 28
    • 4544258485 scopus 로고    scopus 로고
    • Self-representation in the thymus: An extended view
    • Kyewski, B. and Derbinski, J., Self-representation in the thymus: an extended view. Nat. Rev. Immunol. 2004. 4: 688-698.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 688-698
    • Kyewski, B.1    Derbinski, J.2
  • 29
    • 33646165128 scopus 로고    scopus 로고
    • A central role for central tolerance
    • Kyewski, B. and Klein, L., A central role for central tolerance. Annu. Rev. Immunol. 2006. 24: 571-606.
    • (2006) Annu. Rev. Immunol , vol.24 , pp. 571-606
    • Kyewski, B.1    Klein, L.2
  • 30
    • 38649131259 scopus 로고    scopus 로고
    • Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism
    • Derbinski, J., Pinto, S., Rösch, S., Hexel, K. and Kyewski, B., Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism. Proc. Natl. Acad. Sci. USA 2008. 105: 657-662.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 657-662
    • Derbinski, J.1    Pinto, S.2    Rösch, S.3    Hexel, K.4    Kyewski, B.5
  • 31
    • 36749066715 scopus 로고    scopus 로고
    • Developmental pathway of CD4+CD8- medullary thymocytes during mouse ontogeny and its defect in Aire-/- mice
    • Li, J., Li, Y., Yao, J. Y., Jin, R., Zhu, M. Z., Qian, X. P., Zhang, J. et al., Developmental pathway of CD4+CD8- medullary thymocytes during mouse ontogeny and its defect in Aire-/- mice. Proc. Natl. Acad. Sci. USA 2007. 104: 18175-18180.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 18175-18180
    • Li, J.1    Li, Y.2    Yao, J.Y.3    Jin, R.4    Zhu, M.Z.5    Qian, X.P.6    Zhang, J.7
  • 34
    • 33747092627 scopus 로고    scopus 로고
    • T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity
    • Zehn, D. and Bevan, M. J., T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity. Immunity 2006. 25: 261-270.
    • (2006) Immunity , vol.25 , pp. 261-270
    • Zehn, D.1    Bevan, M.J.2
  • 35
    • 34250336454 scopus 로고    scopus 로고
    • RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla
    • Rossi, S. W., Kim, M. Y., Leibbrandt, A., Parnell, S. M., Jenkinson, W. E., Glanville, S. H., McConnell, F. M. et al., RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla. J. Exp. Med. 2007. 204: 1267-1272.
    • (2007) J. Exp. Med , vol.204 , pp. 1267-1272
    • Rossi, S.W.1    Kim, M.Y.2    Leibbrandt, A.3    Parnell, S.M.4    Jenkinson, W.E.5    Glanville, S.H.6    McConnell, F.M.7
  • 36
    • 51349101423 scopus 로고    scopus 로고
    • Autoantigen-specific interactions with CD4+thymocytes control mature medullary thymic epithelial cell cellularity
    • Irla, M., Hugues, S., Gill, J., Nitta, T., Hikosaka, Y., Williams, I. R., Hubert, F. X. et al., Autoantigen-specific interactions with CD4+thymocytes control mature medullary thymic epithelial cell cellularity. Immunity 2008. 29: 451-463.
    • (2008) Immunity , vol.29 , pp. 451-463
    • Irla, M.1    Hugues, S.2    Gill, J.3    Nitta, T.4    Hikosaka, Y.5    Williams, I.R.6    Hubert, F.X.7
  • 37
    • 51349111243 scopus 로고    scopus 로고
    • The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance
    • Akiyama, T., Shimo, Y., Yanai, H., Qin, J., Ohshima, D., Maruyama, Y., Asaumi, Y. et al., The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity 2008. 29: 423-437.
    • (2008) Immunity , vol.29 , pp. 423-437
    • Akiyama, T.1    Shimo, Y.2    Yanai, H.3    Qin, J.4    Ohshima, D.5    Maruyama, Y.6    Asaumi, Y.7
  • 38
    • 51349092893 scopus 로고    scopus 로고
    • The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator
    • Hikosaka, Y., Nitta, T., Ohigashi, I., Yano, K., Ishimaru, N., Hayashi, Y., Matsumoto, M. et al., The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. Immunity 2008. 29: 438-450.
    • (2008) Immunity , vol.29 , pp. 438-450
    • Hikosaka, Y.1    Nitta, T.2    Ohigashi, I.3    Yano, K.4    Ishimaru, N.5    Hayashi, Y.6    Matsumoto, M.7
  • 39
    • 45949094459 scopus 로고    scopus 로고
    • The lymphotoxin pathway regulates Aireindependent expression of ectopic genes and chemokines in thymic stromal cells
    • Seach, N., Ueno, T., Fletcher, A. L., Lowen, T., Mattesich, M., Engwerda, C. R., Scott, H. S. et al., The lymphotoxin pathway regulates Aireindependent expression of ectopic genes and chemokines in thymic stromal cells. J. Immunol. 2008. 180: 5384-5392.
    • (2008) J. Immunol , vol.180 , pp. 5384-5392
    • Seach, N.1    Ueno, T.2    Fletcher, A.L.3    Lowen, T.4    Mattesich, M.5    Engwerda, C.R.6    Scott, H.S.7
  • 40
    • 0037084784 scopus 로고    scopus 로고
    • Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
    • Ramsey, C., Winqvist, O., Puhakka, L., Halonen, M., Moro, A., Kämpe, O., Eskelin, P. et al., Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. Hum. Mol. Genet. 2002. 11: 397-409.
    • (2002) Hum. Mol. Genet , vol.11 , pp. 397-409
    • Ramsey, C.1    Winqvist, O.2    Puhakka, L.3    Halonen, M.4    Moro, A.5    Kämpe, O.6    Eskelin, P.7
  • 42
    • 33847350111 scopus 로고    scopus 로고
    • Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation
    • Gillard, G. O., Dooley, J., Erickson, M., Peltonen, L. and Farr, A. G., Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation. J. Immunol. 2007. 178: 3007-3015.
    • (2007) J. Immunol , vol.178 , pp. 3007-3015
    • Gillard, G.O.1    Dooley, J.2    Erickson, M.3    Peltonen, L.4    Farr, A.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.