Aluminum induces osteoblast apoptosis through the oxidative stress-mediated JNK signaling pathway

Biological Trace Element Research

Volumn 150, Issue 1-3, 2012, Pages 502-508

  Li, Xinwei ^a,b   Han, Yanfei ^b   Guan, Yuan ^a   Zhang, Liang ^a   Bai, Chongsheng ^b   Li, Yanfei ^b  

^a JILIN UNIVERSITY   (China)

^b NORTHEAST AGRICULTURAL UNIVERSITY   (China)

Author keywords

Aluminum; Apoptosis; Bone formation; c Jun N terminal kinase signaling pathway; Osteoblasts

Indexed keywords

ALKALINE PHOSPHATASE; ALUMINUM; CASPASE 3; CASPASE 9; FAS LIGAND; MESSENGER RNA; OSTEOCALCIN; PROTEIN BAX; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BAX GENE; C JUN GENE; CASPASE 3 GENE; CASPASE 9 GENE; CELL COUNT; CELL DAMAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FASL GENE; GENE EXPRESSION; NEWBORN; NONHUMAN; OSSIFICATION; OSTEOBLAST; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ALKALINE PHOSPHATASE; ALUMINUM; ALUMINUM COMPOUNDS; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BIOLOGICAL MARKERS; CELLS, CULTURED; CHLORIDES; DOWN-REGULATION; MAP KINASE SIGNALING SYSTEM; OSTEOBLASTS; OSTEOCALCIN; OSTEOGENESIS; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; SKULL; UP-REGULATION;

EID: 84870687642     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-012-9523-5     Document Type: Article

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