Betulin complex in γ-cyclodextrin derivatives: Properties and antineoplasic activities in in vitro and in vivo tumor models

International Journal of Molecular Sciences

Volumn 13, Issue 11, 2012, Pages 14992-15011

  Şoica, Codruta ^a   Dehelean, Cristina ^a   Danciu, Corina ^a   Wang, Hai Ming ^b   Wenz, Gerhard ^b   Ambrus, Rita ^c   Bojin, Florina ^a   Anghel, Mariana ^a  

^a VICTOR BABES UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Antitumor activity; Betulin; C57BL 6J mice; Cyclodextrin; Immunocytochemistry; Melanoma; MTT

Indexed keywords

BETULIN; GAMMA CYCLODEXTRIN DERIVATIVE; OCTAKIS [6 DEOXY 6 (2 SULFANYL ETHANESULFONATE)] GAMMA CYCLODEXTRIN DERIVATIVE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CASPASE 2; DRUG COMBINATION; TRITERPENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BETULA PENDULA; BIRCH; COMPLEX FORMATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG EFFECT; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MELANOMA; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; SCANNING ELECTRON MICROSCOPY; SKIN CANCER; TUMOR VOLUME; ANIMAL; CELL SURVIVAL; CHEMISTRY; DISEASE MODEL; DRUG COMBINATION; DRUG EFFECTS; DRUG SCREENING; FLOW CYTOMETRY; GENE EXPRESSION; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; CASPASE 2; CELL LINE, TUMOR; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DRUG COMBINATIONS; FLOW CYTOMETRY; GAMMA-CYCLODEXTRINS; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; MELANOMA; MICE; TRITERPENES; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84870677944     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms131114992     Document Type: Article

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