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Volumn 98, Issue 3, 2012, Pages 452-458

Lack of association between genetic polymorphisms within KCNQ1 locus and type 2 diabetes in Tunisian Arabs

Author keywords

Allele; Haplotype; KCNQ1; Tunisia; Type 2 diabetes

Indexed keywords

GLUCOSE; LIPID; POTASSIUM CHANNEL KCNQ1;

EID: 84870676280     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2012.10.006     Document Type: Article
Times cited : (22)

References (33)
  • 1
    • 17044386953 scopus 로고    scopus 로고
    • Type 2 diabetes: principles of pathogenesis and therapy
    • Stumvoll M., Goldstein B.J., van Haeften T.W. Type 2 diabetes: principles of pathogenesis and therapy. Lancet 2005, 365:1333-1346.
    • (2005) Lancet , vol.365 , pp. 1333-1346
    • Stumvoll, M.1    Goldstein, B.J.2    van Haeften, T.W.3
  • 2
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • Zimmet P., Alberti K.G., Shaw J. Global and societal implications of the diabetes epidemic. Nature 2001, 414:782-787.
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2    Shaw, J.3
  • 3
    • 82955247909 scopus 로고    scopus 로고
    • IDF Diabetes Atlas: global estimates of the prevalence of diabetes for 2011 and 2030
    • Whiting D.R., Guariguata L., Weil C., Shaw J. IDF Diabetes Atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res Clin Pract 2011, 94:311-321.
    • (2011) Diabetes Res Clin Pract , vol.94 , pp. 311-321
    • Whiting, D.R.1    Guariguata, L.2    Weil, C.3    Shaw, J.4
  • 4
    • 12344279952 scopus 로고    scopus 로고
    • Genetic factors in type 2 diabetes: the end of the beginning?
    • O'Rahilly S., Barroso I., Wareham N.J. Genetic factors in type 2 diabetes: the end of the beginning?. Science 2005, 307:370-373.
    • (2005) Science , vol.307 , pp. 370-373
    • O'Rahilly, S.1    Barroso, I.2    Wareham, N.J.3
  • 5
    • 33847176604 scopus 로고    scopus 로고
    • A genome-wide association study identifies novel risk loci for type 2 diabetes
    • Sladek R., Rocheleau G., Rung J., Dina C., Shen L., Serre D., et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 2007, 445:881-885.
    • (2007) Nature , vol.445 , pp. 881-885
    • Sladek, R.1    Rocheleau, G.2    Rung, J.3    Dina, C.4    Shen, L.5    Serre, D.6
  • 6
    • 34249888775 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
    • Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research
    • Saxena R., Voight B.F., Lyssenko V., Burtt N.P., de Bakker P.I., et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007, 316:1331-1336. Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research.
    • (2007) Science , vol.316 , pp. 1331-1336
    • Saxena, R.1    Voight, B.F.2    Lyssenko, V.3    Burtt, N.P.4    de Bakker, P.I.5
  • 7
    • 34249895023 scopus 로고    scopus 로고
    • Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
    • Zeggini E., Weedon M.N., Lindgren C.M., Frayling T.M., Elliott K.S., Lango H., et al. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 2007, 316:1336-1341.
    • (2007) Science , vol.316 , pp. 1336-1341
    • Zeggini, E.1    Weedon, M.N.2    Lindgren, C.M.3    Frayling, T.M.4    Elliott, K.S.5    Lango, H.6
  • 8
    • 34249885875 scopus 로고    scopus 로고
    • A genomewide association study of type 2 diabetes in Finns detects multiple susceptibility variants
    • Scott L.J., Mohlke K.L., Bonnycastle L.L. A genomewide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007, 316:1341-1345.
    • (2007) Science , vol.316 , pp. 1341-1345
    • Scott, L.J.1    Mohlke, K.L.2    Bonnycastle, L.L.3
  • 9
    • 58149333712 scopus 로고    scopus 로고
    • Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study
    • van Hoek M., Dehghan A., Witteman J.C., van Duijn C.M., Uitterlinden A.G., Oostra B.A., et al. Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study. Diabetes 2008, 57:3122-3128.
    • (2008) Diabetes , vol.57 , pp. 3122-3128
    • van Hoek, M.1    Dehghan, A.2    Witteman, J.C.3    van Duijn, C.M.4    Uitterlinden, A.G.5    Oostra, B.A.6
  • 10
    • 50449085998 scopus 로고    scopus 로고
    • Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
    • Yasuda K., Miyake K., Horikawa Y., Hara K., Osawa H., Furuta H., et al. Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet 2008, 40:1092-1097.
    • (2008) Nat Genet , vol.40 , pp. 1092-1097
    • Yasuda, K.1    Miyake, K.2    Horikawa, Y.3    Hara, K.4    Osawa, H.5    Furuta, H.6
  • 11
    • 50449085212 scopus 로고    scopus 로고
    • SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
    • Unoki H., Takahashi A., Kawaguchi T., Hara K., Horikoshi M., Andersen G., et al. SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet 2008, 40:1098-1102.
    • (2008) Nat Genet , vol.40 , pp. 1098-1102
    • Unoki, H.1    Takahashi, A.2    Kawaguchi, T.3    Hara, K.4    Horikoshi, M.5    Andersen, G.6
  • 12
    • 67650248695 scopus 로고    scopus 로고
    • Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population
    • Takeuchi F., Serizawa M., Yamamoto K., Fujisawa T., Nakashima E., Ohnaka K., et al. Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. Diabetes 2009, 58:1690-1699.
    • (2009) Diabetes , vol.58 , pp. 1690-1699
    • Takeuchi, F.1    Serizawa, M.2    Yamamoto, K.3    Fujisawa, T.4    Nakashima, E.5    Ohnaka, K.6
  • 13
    • 0032971571 scopus 로고    scopus 로고
    • Genomic organization of the KCNQ1 K_ channel gene and identification of C-terminal mutations in the long-QT syndrome
    • Neyroud N., Richard P., Vignier N., Donger C., Denjoy I., Demay L., et al. Genomic organization of the KCNQ1 K_ channel gene and identification of C-terminal mutations in the long-QT syndrome. Circ Res 1999, 84:290-297.
    • (1999) Circ Res , vol.84 , pp. 290-297
    • Neyroud, N.1    Richard, P.2    Vignier, N.3    Donger, C.4    Denjoy, I.5    Demay, L.6
  • 14
    • 0029952101 scopus 로고    scopus 로고
    • K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current
    • Barhanin J., Lesage F., Guillemare E., Fink M., Lazdunski M., Romey G. K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature 1996, 384:78-80.
    • (1996) Nature , vol.384 , pp. 78-80
    • Barhanin, J.1    Lesage, F.2    Guillemare, E.3    Fink, M.4    Lazdunski, M.5    Romey, G.6
  • 15
    • 0036720536 scopus 로고    scopus 로고
    • Ion channels in secretory granules of the pancreas and their role in exocytosis and release of secretory proteins
    • Thévenod F. Ion channels in secretory granules of the pancreas and their role in exocytosis and release of secretory proteins. Am J Physiol Cell Physiol 2002, 283:C651-C672.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Thévenod, F.1
  • 17
    • 77649214654 scopus 로고    scopus 로고
    • A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese
    • Tsai F.J., Yang C.F., Chen C.C., Chuang L.M., Lu C.H., Chang C.T., et al. A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. PLoS Genet 2010, 6(2):e1000847.
    • (2010) PLoS Genet , vol.6 , Issue.2
    • Tsai, F.J.1    Yang, C.F.2    Chen, C.C.3    Chuang, L.M.4    Lu, C.H.5    Chang, C.T.6
  • 18
    • 77954143522 scopus 로고    scopus 로고
    • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
    • Voight B.F., Scott L.J., Steinthorsdottir V., Morris A.P., Dina C., Welch R.P., et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010, 42:579-589.
    • (2010) Nat Genet , vol.42 , pp. 579-589
    • Voight, B.F.1    Scott, L.J.2    Steinthorsdottir, V.3    Morris, A.P.4    Dina, C.5    Welch, R.P.6
  • 19
    • 78649526616 scopus 로고    scopus 로고
    • Combined effects of 19 common variation on type 2 diabetes in Chinese: results from two community-based studies
    • Xu M., Bi Y.F., Xu Y., Huang Y., Lu W.Y., Gu Y.F., et al. Combined effects of 19 common variation on type 2 diabetes in Chinese: results from two community-based studies. PLoS One 2010, 5:e14022.
    • (2010) PLoS One , vol.5
    • Xu, M.1    Bi, Y.F.2    Xu, Y.3    Huang, Y.4    Lu, W.Y.5    Gu, Y.F.6
  • 20
    • 78751647900 scopus 로고    scopus 로고
    • Variants in KCNQ1 increase type II diabetes susceptibility in South Asians: a study of 3,310 subjects from India and the US
    • Been L.F., Ralhan S., Wander G.S., Mehra N.K., Singh J.R., Mulvihill J.J., et al. Variants in KCNQ1 increase type II diabetes susceptibility in South Asians: a study of 3,310 subjects from India and the US. BMC Med Genet 2011, 12:18.
    • (2011) BMC Med Genet , vol.12 , pp. 18
    • Been, L.F.1    Ralhan, S.2    Wander, G.S.3    Mehra, N.K.4    Singh, J.R.5    Mulvihill, J.J.6
  • 21
    • 80052517091 scopus 로고    scopus 로고
    • Replication of 13 genome-wide association (GWA)-validated risk variants for type 2 diabetes in Pakistani populations
    • Rees S.D., Hydrie M.Z., Shera A.S., Kumar S., O'Hare J.P., Barnett A.H., et al. Replication of 13 genome-wide association (GWA)-validated risk variants for type 2 diabetes in Pakistani populations. Diabetologia 2011, 54:1368-1374.
    • (2011) Diabetologia , vol.54 , pp. 1368-1374
    • Rees, S.D.1    Hydrie, M.Z.2    Shera, A.S.3    Kumar, S.4    O'Hare, J.P.5    Barnett, A.H.6
  • 22
    • 67649974089 scopus 로고    scopus 로고
    • The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load
    • Holmkvist J., Banasik K., Andersen G., Unoki H., Jensen T.S., Pisinger C., et al. The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load. PLoS One 2009, 4(6):e5872.
    • (2009) PLoS One , vol.4 , Issue.6
    • Holmkvist, J.1    Banasik, K.2    Andersen, G.3    Unoki, H.4    Jensen, T.S.5    Pisinger, C.6
  • 23
    • 70349640785 scopus 로고    scopus 로고
    • A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion
    • Jonsson A., Isomaa B., Tuomi T., Taneera J., Salehi A., Nilsson P., et al. A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion. Diabetes 2009, 58:2409-2413.
    • (2009) Diabetes , vol.58 , pp. 2409-2413
    • Jonsson, A.1    Isomaa, B.2    Tuomi, T.3    Taneera, J.4    Salehi, A.5    Nilsson, P.6
  • 24
    • 67650251656 scopus 로고    scopus 로고
    • Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion
    • Müssig K., Staiger H., Machicao F., Kirchhoff K., Guthoff M., Schäfer S.A., et al. Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion. Diabetes 2009, 58:1715-1720.
    • (2009) Diabetes , vol.58 , pp. 1715-1720
    • Müssig, K.1    Staiger, H.2    Machicao, F.3    Kirchhoff, K.4    Guthoff, M.5    Schäfer, S.A.6
  • 25
    • 66649101376 scopus 로고    scopus 로고
    • Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3734 subjects comprising three ethnicities living in Singapore
    • Tan J.T., Nurbaya S., Gardner D., Sandra Y., Tai E.S., Ng D.P. Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3734 subjects comprising three ethnicities living in Singapore. Diabetes 2009, 58:1445-1449.
    • (2009) Diabetes , vol.58 , pp. 1445-1449
    • Tan, J.T.1    Nurbaya, S.2    Gardner, D.3    Sandra, Y.4    Tai, E.S.5    Ng, D.P.6
  • 26
    • 69449108010 scopus 로고    scopus 로고
    • Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population
    • Qi Q., Li H., Loos R.J., Liu C., Wu Y., Hu F.B., et al. Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population. Hum Mol Genet 2009, 18:3508-3515.
    • (2009) Hum Mol Genet , vol.18 , pp. 3508-3515
    • Qi, Q.1    Li, H.2    Loos, R.J.3    Liu, C.4    Wu, Y.5    Hu, F.B.6
  • 27
    • 67349205597 scopus 로고    scopus 로고
    • Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population
    • Hu C., Wang C., Zhang R., Ma X., Wang J., Lu J., et al. Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population. Diabetologia 2009, 52:1322-1325.
    • (2009) Diabetologia , vol.52 , pp. 1322-1325
    • Hu, C.1    Wang, C.2    Zhang, R.3    Ma, X.4    Wang, J.5    Lu, J.6
  • 28
    • 34948845069 scopus 로고    scopus 로고
    • Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population
    • Chang Y.C., Chang T.J., Jiang Y.D., Kuo S.S., Lee K.C., Chiu K.C., et al. Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population. Diabetes 2007, 56:2631-2637.
    • (2007) Diabetes , vol.56 , pp. 2631-2637
    • Chang, Y.C.1    Chang, T.J.2    Jiang, Y.D.3    Kuo, S.S.4    Lee, K.C.5    Chiu, K.C.6
  • 30
    • 67349097455 scopus 로고    scopus 로고
    • Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China
    • Liu Y., Zhou D.Z., Zhang D., Chen Z., Zhao T., Zhang Z., et al. Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China. Diabetologia 2009, 52:1315-1321.
    • (2009) Diabetologia , vol.52 , pp. 1315-1321
    • Liu, Y.1    Zhou, D.Z.2    Zhang, D.3    Chen, Z.4    Zhao, T.5    Zhang, Z.6
  • 31
    • 23044436742 scopus 로고    scopus 로고
    • Studies of variations of the cyclin-dependent kinase inhibitor 1C and the cyclin-dependent kinase 4 genes in relation to type 2 diabetes mellitus and related quantitative traits
    • Nielsen E.-M., Hansen L., Stissing T., Yanagisawa K., Borch-Johnsen K., Poulsen P., et al. Studies of variations of the cyclin-dependent kinase inhibitor 1C and the cyclin-dependent kinase 4 genes in relation to type 2 diabetes mellitus and related quantitative traits. J Mol Med 2005, 83:353-361.
    • (2005) J Mol Med , vol.83 , pp. 353-361
    • Nielsen, E.-M.1    Hansen, L.2    Stissing, T.3    Yanagisawa, K.4    Borch-Johnsen, K.5    Poulsen, P.6
  • 32
    • 0034929557 scopus 로고    scopus 로고
    • KCNQ potassium channels: physiology, pathophysiology, and pharmacology
    • Robbins J. KCNQ potassium channels: physiology, pathophysiology, and pharmacology. Pharmacol Ther 2001, 90:1-19.
    • (2001) Pharmacol Ther , vol.90 , pp. 1-19
    • Robbins, J.1
  • 33
    • 75149150236 scopus 로고    scopus 로고
    • Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore
    • Tan J.T., Ng D.P., Nurbaya S., Ye S., Lim X.L., Leong H., et al. Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore. J Clin Endocrinol Metab 2010, 95:390-397.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 390-397
    • Tan, J.T.1    Ng, D.P.2    Nurbaya, S.3    Ye, S.4    Lim, X.L.5    Leong, H.6


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