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Volumn 35, Issue 10, 2012, Pages 832-839

The use of antimicrobial-impregnated PMMA to manage periprosthetic infections: Controversial issues and the latest developments

Author keywords

Antimicrobial agent; Arthroplasty; Periprosthetic infection; PMMA bone cements

Indexed keywords

ANTIBIOTICS; ANTIMICROBIAL AGENTS; BONE; BONE CEMENT; CARDIOVASCULAR SYSTEM; CHITOSAN; DRUG DELIVERY; MICROORGANISMS; ORTHOPEDICS;

EID: 84870565849     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.5301/ijao.5000163     Document Type: Article
Times cited : (38)

References (75)
  • 1
    • 77955390698 scopus 로고    scopus 로고
    • Factors affecting the incidence of infection in hip and knee replacement: An analysis of 5277 cases
    • Willis-Owen CA, Konyves A, Martin DK. Factors affecting the incidence of infection in hip and knee replacement: an analysis of 5277 cases. J Bone Joint Surg Br. 2010;92(8):1128-1133.
    • (2010) J Bone Joint Surg Br , vol.92 , Issue.8 , pp. 1128-1133
    • Willis-Owen, C.A.1    Konyves, A.2    Martin, D.K.3
  • 3
    • 84862873111 scopus 로고    scopus 로고
    • Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials
    • Arciola CR, Campoccia D, Speziale P, Montanaro L, Costerton JW. Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials. Biomaterials. 2012;33(26): 5967-5982.
    • (2012) Biomaterials , vol.33 , Issue.26 , pp. 5967-5982
    • Arciola, C.R.1    Campoccia, D.2    Speziale, P.3    Montanaro, L.4    Costerton, J.W.5
  • 4
    • 81355136181 scopus 로고    scopus 로고
    • Antibiotic-induced biofilm formation
    • Kaplan JB. Antibiotic-induced biofilm formation. Int J Artif Organs. 2011;34(9):737-751.
    • (2011) Int J Artif Organs , vol.34 , Issue.9 , pp. 737-751
    • Kaplan, J.B.1
  • 5
    • 36048996366 scopus 로고    scopus 로고
    • Titania nanotubes: A novel platform for drug-eluting coatings for medical implants?
    • Popat KC, Eltgroth M, LaTempa TJ, Grimes CA, Desai TA. Titania nanotubes: a novel platform for drug-eluting coatings for medical implants? Small. 2007;3(11):1878-1881.
    • (2007) Small , vol.3 , Issue.11 , pp. 1878-1881
    • Popat, K.C.1    Eltgroth, M.2    Latempa, T.J.3    Grimes, C.A.4    Desai, T.A.5
  • 6
    • 77952327337 scopus 로고    scopus 로고
    • Polymethylmethacrylate: Properties and contemporary uses in orthopaedics
    • Jaeblon T. Polymethylmethacrylate: properties and contemporary uses in orthopaedics. J Am Acad Orthop Surg. 2010;18(5):297-305.
    • (2010) J Am Acad Orthop Surg , vol.18 , Issue.5 , pp. 297-305
    • Jaeblon, T.1
  • 7
    • 81555200474 scopus 로고    scopus 로고
    • In vitro activities of daptomycin-, vancomycin-, and teicoplanin-loaded polymethylmethacrylate against methicillin-susceptible, methicillin- resistant, and vancomycin-intermediate strains of Staphylococcus aureus
    • Chang Y, Chen WC, Hsieh PH, et al. In vitro activities of daptomycin-, vancomycin-, and teicoplanin-loaded polymethylmethacrylate against methicillin-susceptible, methicillin- resistant, and vancomycin-intermediate strains of Staphylococcus aureus. Antimicrob Agents Chemother. 2011;55(12):5480-5484.
    • (2011) Antimicrob Agents Chemother , vol.55 , Issue.12 , pp. 5480-5484
    • Chang, Y.1    Chen, W.C.2    Hsieh, P.H.3
  • 8
    • 78149254594 scopus 로고    scopus 로고
    • Gentamicin release from commercially-available gentamicinloaded PMMA bone cements in a prosthesis-related interfacial gap model and their antibacterial efficacy
    • Neut D, Kluin OS, Thompson J, van der Mei HC, Busscher HJ. Gentamicin release from commercially-available gentamicinloaded PMMA bone cements in a prosthesis-related interfacial gap model and their antibacterial efficacy. BMC Musculoskelet Disord. 2010;11:258.
    • (2010) BMC Musculoskelet Disord , vol.11 , pp. 258
    • Neut, D.1    Kluin, O.S.2    Thompson, J.3    van der Mei, H.C.4    Busscher, H.J.5
  • 9
    • 81355132377 scopus 로고    scopus 로고
    • New trends in diagnosis and control strategies for implant infections
    • Arciola CR, Montanaro L, Costerton JW. New trends in diagnosis and control strategies for implant infections. Int J Artif Organs. 2011;34(9):727-736.
    • (2011) Int J Artif Organs , vol.34 , Issue.9 , pp. 727-736
    • Arciola, C.R.1    Montanaro, L.2    Costerton, J.W.3
  • 10
    • 77953948370 scopus 로고    scopus 로고
    • A simple method for fashioning an antibiotic cement-coated interlocking intramedullary nail
    • Riel RU, Gladden PB. A simple method for fashioning an antibiotic cement-coated interlocking intramedullary nail. Am J Orthop (Belle Mead NJ). 2010;39(1):18-21.
    • (2010) Am J Orthop (Belle Mead NJ) , vol.39 , Issue.1 , pp. 18-21
    • Riel, R.U.1    Gladden, P.B.2
  • 11
    • 65449156489 scopus 로고    scopus 로고
    • Elution of gentamicin and vancomycin from polymethylmethacrylate beads and hip spacers in vivo
    • Anagnostakos K, Wilmes P, Schmitt E, Kelm J. Elution of gentamicin and vancomycin from polymethylmethacrylate beads and hip spacers in vivo. Acta Orthop. 2009;80(2): 193-197.
    • (2009) Acta Orthop , vol.80 , Issue.2 , pp. 193-197
    • Anagnostakos, K.1    Wilmes, P.2    Schmitt, E.3    Kelm, J.4
  • 12
    • 81255157135 scopus 로고    scopus 로고
    • Scenery of Staphylococcus implant infections in orthopedics
    • Montanaro L, Speziale P, Campoccia D, et al. Scenery of Staphylococcus implant infections in orthopedics. Future Microbiol. 2011;6(11):1329-1349.
    • (2011) Future Microbiol , vol.6 , Issue.11 , pp. 1329-1349
    • Montanaro, L.1    Speziale, P.2    Campoccia, D.3
  • 13
    • 79955888412 scopus 로고    scopus 로고
    • Effect of various concentrations of antibiotics on osteogenic cell viability and activity
    • Rathbone CR, Cross JD, Brown KV, Murray CK, Wenke JC. Effect of various concentrations of antibiotics on osteogenic cell viability and activity. J Orthop Res. 2011;29(7): 1070-1074.
    • (2011) J Orthop Res , vol.29 , Issue.7 , pp. 1070-1074
    • Rathbone, C.R.1    Cross, J.D.2    Brown, K.V.3    Murray, C.K.4    Wenke, J.C.5
  • 14
    • 0036563184 scopus 로고    scopus 로고
    • Cefuroximeimpregnated cement in primary total knee arthroplasty: A prospective, randomized study of three hundred and forty knees
    • Chiu FY, Chen CM, Lin CFJ, Lo WH. Cefuroximeimpregnated cement in primary total knee arthroplasty: a prospective, randomized study of three hundred and forty knees. J Bone Joint Surg Am. 2002;84-A:759-762.
    • (2002) J Bone Joint Surg Am , vol.84 , pp. 759-762
    • Chiu, F.Y.1    Chen, C.M.2    Lin, C.F.J.3    Lo, W.H.4
  • 15
    • 0034917044 scopus 로고    scopus 로고
    • Cefuroximeimpregnated cement at primary total knee arthroplasty in diabetes mellitus. A prospective, randomised study
    • Chiu FY, Lin CF, Chen CM, Lo WH, Chaung TY. Cefuroximeimpregnated cement at primary total knee arthroplasty in diabetes mellitus. A prospective, randomised study. J Bone Joint Surg Br. 2001;83(5):691-695.
    • (2001) J Bone Joint Surg Br , vol.83 , Issue.5 , pp. 691-695
    • Chiu, F.Y.1    Lin, C.F.2    Chen, C.M.3    Lo, W.H.4    Chaung, T.Y.5
  • 16
    • 62549164780 scopus 로고    scopus 로고
    • Antibiotic-impregnated cement in revision total knee arthroplasty. A prospective cohort study of one hundred and eighty-three knees
    • Chiu FY, Lin CF. Antibiotic-impregnated cement in revision total knee arthroplasty. A prospective cohort study of one hundred and eighty-three knees. J Bone Joint Surg Am. 2009;91(3):628-633.
    • (2009) J Bone Joint Surg Am , vol.91 , Issue.3 , pp. 628-633
    • Chiu, F.Y.1    Lin, C.F.2
  • 17
    • 0030738582 scopus 로고    scopus 로고
    • Antibiotic prophylaxis in total hip arthroplasty. Review of 10,905 primary cemented total hip replacements reported to the Norwegian arthroplasty register, 1987 to 1995
    • Espehaug B, Engesaeter LB, Vollset SE, Havelin LI, Langeland N. Antibiotic prophylaxis in total hip arthroplasty. Review of 10,905 primary cemented total hip replacements reported to the Norwegian arthroplasty register, 1987 to 1995. J Bone Joint Surg Br. 1997;79(4):590-595.
    • (1997) J Bone Joint Surg Br , vol.79 , Issue.4 , pp. 590-595
    • Espehaug, B.1    Engesaeter, L.B.2    Vollset, S.E.3    Havelin, L.I.4    Langeland, N.5
  • 19
    • 82255176845 scopus 로고    scopus 로고
    • Infection after primary hip arthroplasty: A comparison of 3 Norwegian health registers
    • Dale H, Skråmm I, Løwer HL, et al. Infection after primary hip arthroplasty: a comparison of 3 Norwegian health registers. Acta Orthop. 2011;82(6):646-654.
    • (2011) Acta Orthop , vol.82 , Issue.6 , pp. 646-654
    • Dale, H.1    Skråmm, I.2    Løwer, H.L.3
  • 20
    • 84870532197 scopus 로고    scopus 로고
    • Australian Orthopaedic Association, Annual Report. Australian Orthopaedic Association, Adelaide, Available online at
    • Australian Orthopaedic Association. National Joint Registry. Annual Report. Australian Orthopaedic Association, Adelaide 2009. Available online at www.aoa.org.au.
    • (2009) National Joint Registry
  • 22
    • 77957915714 scopus 로고    scopus 로고
    • Risk factors for revision due to infection after primary total hip arthroplasty. A population-based study of 80,756 primary procedures in the Danish Hip Arthroplasty Registry
    • Pedersen AB, Svendsson JE, Johnsen SP, Riis A, Overgaard S. Risk factors for revision due to infection after primary total hip arthroplasty. A population-based study of 80,756 primary procedures in the Danish Hip Arthroplasty Registry. Acta Orthop. 2010;81(5):542-547.
    • (2010) Acta Orthop , vol.81 , Issue.5 , pp. 542-547
    • Pedersen, A.B.1    Svendsson, J.E.2    Johnsen, S.P.3    Riis, A.4    Overgaard, S.5
  • 23
    • 73149119375 scopus 로고    scopus 로고
    • Incidence of prosthetic joint infections after primary knee arthroplasty
    • Jämsen E, Varonen M, Huhtala H, et al. Incidence of prosthetic joint infections after primary knee arthroplasty. J Arthroplasty. 2010;25(1):87-92.
    • (2010) J Arthroplasty , vol.25 , Issue.1 , pp. 87-92
    • Jämsen, E.1    Varonen, M.2    Huhtala, H.3
  • 24
    • 47249159028 scopus 로고    scopus 로고
    • Efficacy of antibiotic-impregnated cement in total hip replacement
    • Parvizi J, Saleh KJ, Ragland PS, Pour AE, Mont MA. Efficacy of antibiotic-impregnated cement in total hip replacement. Acta Orthop. 2008;79(3):335-341.
    • (2008) Acta Orthop , vol.79 , Issue.3 , pp. 335-341
    • Parvizi, J.1    Saleh, K.J.2    Ragland, P.S.3    Pour, A.E.4    Mont, M.A.5
  • 25
    • 70349236021 scopus 로고    scopus 로고
    • Antibiotic bone cement and the incidence of deep infection after total knee arthroplasty
    • Gandhi R, Razak F, Pathy R, Davey JR, Syed K, Mahomed NN. Antibiotic bone cement and the incidence of deep infection after total knee arthroplasty. J Arthroplasty. 2009;24(7): 1015-1018.
    • (2009) J Arthroplasty , vol.24 , Issue.7 , pp. 1015-1018
    • Gandhi, R.1    Razak, F.2    Pathy, R.3    Davey, J.R.4    Syed, K.5    Mahomed, N.N.6
  • 26
    • 68749117413 scopus 로고    scopus 로고
    • Outcomes of routine use of antibiotic-loaded cement in primary total knee arthroplasty
    • Namba RS, Chen Y, Paxton EW, Slipchenko T, Fithian DC. Outcomes of routine use of antibiotic-loaded cement in primary total knee arthroplasty. J Arthroplasty. 2009;24(6) (Suppl):44-47.
    • (2009) J Arthroplasty , vol.24 , Issue.6 SUPPL. , pp. 44-47
    • Namba, R.S.1    Chen, Y.2    Paxton, E.W.3    Slipchenko, T.4    Fithian, D.C.5
  • 27
    • 2942528790 scopus 로고    scopus 로고
    • Prophylactic use of antibiotic bone cement: An emerging standard-in opposition
    • Hanssen AD. Prophylactic use of antibiotic bone cement: an emerging standard-in opposition. J Arthroplasty. 2004;19(4) (Suppl 1):73-77.
    • (2004) J Arthroplasty , vol.19 , Issue.4 SUPPL. 1 , pp. 73-77
    • Hanssen, A.D.1
  • 28
    • 0242441677 scopus 로고    scopus 로고
    • Total knee replacement in patients with diabetes mellitus
    • Meding JB, Reddleman K, Keating ME, et al. Total knee replacement in patients with diabetes mellitus. Clin Orthop Relat Res. 2003;416(416):208-216.
    • (2003) Clin Orthop Relat Res , vol.416 , Issue.416 , pp. 208-216
    • Meding, J.B.1    Reddleman, K.2    Keating, M.E.3
  • 29
    • 57149118875 scopus 로고    scopus 로고
    • Incidence and risk factors of prosthetic joint infection after total hip or knee replacement in patients with rheumatoid arthritis
    • Bongartz T, Halligan CS, Osmon DR, et al. Incidence and risk factors of prosthetic joint infection after total hip or knee replacement in patients with rheumatoid arthritis. Arthritis Rheum. 2008;59(12):1713-1720.
    • (2008) Arthritis Rheum , vol.59 , Issue.12 , pp. 1713-1720
    • Bongartz, T.1    Halligan, C.S.2    Osmon, D.R.3
  • 32
    • 47549099250 scopus 로고    scopus 로고
    • Evaluation and management of the infected total hip and knee
    • Moyad TF, Thornhill T, Estok D. Evaluation and management of the infected total hip and knee. Orthopedics. 2008;31(6):581-588.
    • (2008) Orthopedics , vol.31 , Issue.6 , pp. 581-588
    • Moyad, T.F.1    Thornhill, T.2    Estok, D.3
  • 33
    • 79955940549 scopus 로고    scopus 로고
    • Infection in total hip replacement: Meta-analysis
    • Senthi S, Munro JT, Pitto RP. Infection in total hip replacement: meta-analysis. Int Orthop. 2011;35(2):253-260.
    • (2011) Int Orthop , vol.35 , Issue.2 , pp. 253-260
    • Senthi, S.1    Munro, J.T.2    Pitto, R.P.3
  • 34
    • 79751492089 scopus 로고    scopus 로고
    • Infectiological, functional, and radiographic outcome after revision for prosthetic hip infection according to a strict algorithm
    • De Man FH, Sendi P, Zimmerli W, Maurer TB, Ochsner PE, Ilchmann T. Infectiological, functional, and radiographic outcome after revision for prosthetic hip infection according to a strict algorithm. Acta Orthop. 2011;82(1):27-34.
    • (2011) Acta Orthop , vol.82 , Issue.1 , pp. 27-34
    • de Man, F.H.1    Sendi, P.2    Zimmerli, W.3    Maurer, T.B.4    Ochsner, P.E.5    Ilchmann, T.6
  • 35
    • 70349774932 scopus 로고    scopus 로고
    • Onestage cementless revision arthroplasty for infected hip replacements
    • Yoo JJ, Kwon YS, Koo KH, Yoon KS, Kim YM, Kim HJ. Onestage cementless revision arthroplasty for infected hip replacements. Int Orthop. 2009;33(5):1195-1201.
    • (2009) Int Orthop , vol.33 , Issue.5 , pp. 1195-1201
    • Yoo, J.J.1    Kwon, Y.S.2    Koo, K.H.3    Yoon, K.S.4    Kim, Y.M.5    Kim, H.J.6
  • 36
    • 70349919622 scopus 로고    scopus 로고
    • Rationale for one stage exchange of infected hip replacement using uncemented implants and antibiotic impregnated bone graft
    • Winkler H. Rationale for one stage exchange of infected hip replacement using uncemented implants and antibiotic impregnated bone graft. Int J Med Sci. 2009;6(5):247-252.
    • (2009) Int J Med Sci , vol.6 , Issue.5 , pp. 247-252
    • Winkler, H.1
  • 37
    • 0033660155 scopus 로고    scopus 로고
    • Limited role of direct exchange arthroplasty in the treatment of infected total hip replacements
    • Jackson WO, Schmalzried TP. Limited role of direct exchange arthroplasty in the treatment of infected total hip replacements. Clin Orthop Relat Res. 2000;381(381): 101-105.
    • (2000) Clin Orthop Relat Res , vol.381 , Issue.381 , pp. 101-105
    • Jackson, W.O.1    Schmalzried, T.P.2
  • 38
    • 84859471707 scopus 로고    scopus 로고
    • Chronic infections in hip arthroplasties: Comparing risk of reinfection following one-stage and two-stage revision: A systematic review and meta-analysis
    • Lange J, Troelsen A, Thomsen RW, Søballe K. Chronic infections in hip arthroplasties: comparing risk of reinfection following one-stage and two-stage revision: a systematic review and meta-analysis. Clin Epidemiol. 2012;4:57-73.
    • (2012) Clin Epidemiol , vol.4 , pp. 57-73
    • Lange, J.1    Troelsen, A.2    Thomsen, R.W.3    Søballe, K.4
  • 39
    • 79959573633 scopus 로고    scopus 로고
    • Does cyclical loading affect the elution of antibiotics from articulating cement knee spacers?
    • Rogers BA, Middleton FR, Shearwood-Porter N, et al. Does cyclical loading affect the elution of antibiotics from articulating cement knee spacers? J Bone Joint Surg Br. 2011;93(7):914-920.
    • (2011) J Bone Joint Surg Br , vol.93 , Issue.7 , pp. 914-920
    • Rogers, B.A.1    Middleton, F.R.2    Shearwood-Porter, N.3
  • 41
    • 53449094563 scopus 로고    scopus 로고
    • Hand-made articulating spacers in two-stage revision for infected total knee arthroplasty: Good outcome in 30 patients
    • Villanueva-Martínez M, Ríos-Luna A, Pereiro J, Fahandez-Saddi H, Villamor A. Hand-made articulating spacers in two-stage revision for infected total knee arthroplasty: good outcome in 30 patients. Acta Orthop. 2008;79(5): 674-682.
    • (2008) Acta Orthop , vol.79 , Issue.5 , pp. 674-682
    • Villanueva-Martínez, M.1    Ríos-Luna, A.2    Pereiro, J.3    Fahandez-Saddi, H.4    Villamor, A.5
  • 43
    • 34248359990 scopus 로고    scopus 로고
    • Prospective study of the treatment of infected hip arthroplasties with or without the use of an antibiotic-loaded cement spacer
    • Cabrita HB, Croci AT, Camargo OP, Lima AL. Prospective study of the treatment of infected hip arthroplasties with or without the use of an antibiotic-loaded cement spacer. Clinics (Sao Paulo). 2007;62(2):99-108.
    • (2007) Clinics (Sao Paulo) , vol.62 , Issue.2 , pp. 99-108
    • Cabrita, H.B.1    Croci, A.T.2    Camargo, O.P.3    Lima, A.L.4
  • 44
    • 5444269505 scopus 로고    scopus 로고
    • Practical applications of antibiotic- loaded bone cement for treatment of infected joint replacements
    • Hanssen AD, Spangehl MJ. Practical applications of antibiotic- loaded bone cement for treatment of infected joint replacements. Clin Orthop Relat Res. 2004;427(427):79-85.
    • (2004) Clin Orthop Relat Res , vol.427 , Issue.427 , pp. 79-85
    • Hanssen, A.D.1    Spangehl, M.J.2
  • 45
    • 65449156489 scopus 로고    scopus 로고
    • Elution of gentamicin and vancomycin from polymethylmethacrylate beads and hip spacers in vivo
    • Anagnostakos K, Wilmes P, Schmitt E, Kelm J. Elution of gentamicin and vancomycin from polymethylmethacrylate beads and hip spacers in vivo. Acta Orthop. 2009;80(2): 193-197.
    • (2009) Acta Orthop , vol.80 , Issue.2 , pp. 193-197
    • Anagnostakos, K.1    Wilmes, P.2    Schmitt, E.3    Kelm, J.4
  • 47
    • 34848814456 scopus 로고    scopus 로고
    • Antibiotic-loaded cement articulating spacer for 2-stage reimplantation in infected total knee arthroplasty: A simple and economic method
    • Hsu YC, Cheng HC, Ng TP, Chiu KY. Antibiotic-loaded cement articulating spacer for 2-stage reimplantation in infected total knee arthroplasty: a simple and economic method. J Arthroplasty. 2007;22(7):1060-1066.
    • (2007) J Arthroplasty , vol.22 , Issue.7 , pp. 1060-1066
    • Hsu, Y.C.1    Cheng, H.C.2    Ng, T.P.3    Chiu, K.Y.4
  • 48
    • 82455162733 scopus 로고    scopus 로고
    • An intraoperatively moulded PMMA prostheses like spacer for twostage revision of infected total knee arthroplasty
    • Kohl S, Evangelopoulos DS, Kohlhof H, et al. An intraoperatively moulded PMMA prostheses like spacer for twostage revision of infected total knee arthroplasty. Knee. 2011;18(6):464-469.
    • (2011) Knee , vol.18 , Issue.6 , pp. 464-469
    • Kohl, S.1    Evangelopoulos, D.S.2    Kohlhof, H.3
  • 49
    • 11844277566 scopus 로고    scopus 로고
    • Treatment of infected total knee arthroplasty using an articulating spacer: 2- to 12-year experience
    • Hofmann AA, Goldberg T, Tanner AM, Kurtin SM. Treatment of infected total knee arthroplasty using an articulating spacer: 2- to 12-year experience. Clin Orthop Relat Res. 2005;430(430):125-131.
    • (2005) Clin Orthop Relat Res , vol.430 , Issue.430 , pp. 125-131
    • Hofmann, A.A.1    Goldberg, T.2    Tanner, A.M.3    Kurtin, S.M.4
  • 50
    • 77953959608 scopus 로고    scopus 로고
    • Intraoperatively-made cement- on-cement antibiotic-loaded articulating spacer for infected total knee arthroplasty
    • Shen H, Zhang X, Jiang Y, et al. Intraoperatively-made cement- on-cement antibiotic-loaded articulating spacer for infected total knee arthroplasty. Knee. 2010;17(6):407-411.
    • (2010) Knee , vol.17 , Issue.6 , pp. 407-411
    • Shen, H.1    Zhang, X.2    Jiang, Y.3
  • 51
    • 23844526233 scopus 로고    scopus 로고
    • Antibiotic-loaded cement in total hip replacement: Current indications, efficacy, and complications
    • Jiranek W. Antibiotic-loaded cement in total hip replacement: current indications, efficacy, and complications. Orthopedics. 2005;28(8)(Suppl):s873-s877.
    • (2005) Orthopedics , vol.28 , Issue.8 SUPPL.
    • Jiranek, W.1
  • 52
    • 80054086335 scopus 로고    scopus 로고
    • Surgical procedures in the treatment of 784 infected THAs reported to the Norwegian Arthroplasty Register
    • Engesæter LB, Dale H, Schrama JC, Hallan G, Lie SA. Surgical procedures in the treatment of 784 infected THAs reported to the Norwegian Arthroplasty Register. Acta Orthop. 2011;82(5):530-537.
    • (2011) Acta Orthop , vol.82 , Issue.5 , pp. 530-537
    • Engesæter, L.B.1    Dale, H.2    Schrama, J.C.3    Hallan, G.4    Lie, S.A.5
  • 53
    • 77953959738 scopus 로고    scopus 로고
    • Antibiotic- loaded biomaterials and the risks for the spread of antibiotic resistance following their prophylactic and therapeutic clinical use
    • Campoccia D, Montanaro L, Speziale P, Arciola CR. Antibiotic- loaded biomaterials and the risks for the spread of antibiotic resistance following their prophylactic and therapeutic clinical use. Biomaterials. 2010;31(25):6363-6377.
    • (2010) Biomaterials , vol.31 , Issue.25 , pp. 6363-6377
    • Campoccia, D.1    Montanaro, L.2    Speziale, P.3    Arciola, C.R.4
  • 54
    • 0024432430 scopus 로고
    • Deep infection of cemented total hip arthroplasties caused by coagulase-negative staphylococci
    • Hope PG, Kristinsson KG, Norman P, Elson RA. Deep infection of cemented total hip arthroplasties caused by coagulase-negative staphylococci. J Bone Joint Surg Br. 1989;71(5):851-855.
    • (1989) J Bone Joint Surg Br , vol.71 , Issue.5 , pp. 851-855
    • Hope, P.G.1    Kristinsson, K.G.2    Norman, P.3    Elson, R.A.4
  • 55
    • 0036322652 scopus 로고    scopus 로고
    • Development of resistant strains of Staphylococcus epidermidis on gentamicin- loaded bone cement in vivo
    • Thomes B, Murray P, Bouchier-Hayes D. Development of resistant strains of Staphylococcus epidermidis on gentamicin- loaded bone cement in vivo. J Bone Joint Surg Br. 2002;84(5):758-760.
    • (2002) J Bone Joint Surg Br , vol.84 , Issue.5 , pp. 758-760
    • Thomes, B.1    Murray, P.2    Bouchier-Hayes, D.3
  • 56
    • 2342507884 scopus 로고    scopus 로고
    • Vancomycin-resistant Staphylococcus aureus in the absence of vancomycin exposure
    • Whitener CJ, Park SY, Browne FA, et al. Vancomycin-resistant Staphylococcus aureus in the absence of vancomycin exposure. Clin Infect Dis. 2004;38(8):1049-1055.
    • (2004) Clin Infect Dis , vol.38 , Issue.8 , pp. 1049-1055
    • Whitener, C.J.1    Park, S.Y.2    Browne, F.A.3
  • 58
    • 0034849759 scopus 로고    scopus 로고
    • In vitro adherence and accumulation of Staphylococcus epidermidis RP 62 A and Staphylococcus epidermidis M7 on four different bone cements
    • König DP, Schierholz JM, Hilgers RD, Bertram C, Perdreau-Remington F, Rütt J. In vitro adherence and accumulation of Staphylococcus epidermidis RP 62 A and Staphylococcus epidermidis M7 on four different bone cements. Langenbecks Arch Surg. 2001;386(5):328-332.
    • (2001) Langenbecks Arch Surg , vol.386 , Issue.5 , pp. 328-332
    • König, D.P.1    Schierholz, J.M.2    Hilgers, R.D.3    Bertram, C.4    Perdreau-Remington, F.5    Rütt, J.6
  • 59
    • 44249122839 scopus 로고    scopus 로고
    • Persistence of bacterial growth on antibiotic-loaded beads: Is it actually a problem?
    • Anagnostakos K, Hitzler P, Pape D, Kohn D, Kelm J. Persistence of bacterial growth on antibiotic-loaded beads: is it actually a problem? Acta Orthop. 2008;79(2):302-307.
    • (2008) Acta Orthop , vol.79 , Issue.2 , pp. 302-307
    • Anagnostakos, K.1    Hitzler, P.2    Pape, D.3    Kohn, D.4    Kelm, J.5
  • 60
    • 0035875979 scopus 로고    scopus 로고
    • Staphylococcus aureus biofilm formation on different gentamicin-loaded polymethylmethacrylate bone cements
    • van de Belt H, Neut D, Schenk W, van Horn JR, van Der Mei HC, Busscher HJ. Staphylococcus aureus biofilm formation on different gentamicin-loaded polymethylmethacrylate bone cements. Biomaterials. 2001;22(12):1607-1611.
    • (2001) Biomaterials , vol.22 , Issue.12 , pp. 1607-1611
    • van de Belt, H.1    Neut, D.2    Schenk, W.3    van Horn, J.R.4    van der Mei, H.C.5    Busscher, H.J.6
  • 61
    • 36048961413 scopus 로고    scopus 로고
    • Strong biofilm production, antibiotic multi-resistance and high gelE expression in epidemic clones of Enterococcus faecalis from orthopaedic implant infections
    • Arciola CR, Baldassarri L, Campoccia D, et al. Strong biofilm production, antibiotic multi-resistance and high gelE expression in epidemic clones of Enterococcus faecalis from orthopaedic implant infections. Biomaterials. 2008;29(5):580-586.
    • (2008) Biomaterials , vol.29 , Issue.5 , pp. 580-586
    • Arciola, C.R.1    Baldassarri, L.2    Campoccia, D.3
  • 62
    • 38749125864 scopus 로고    scopus 로고
    • In vitro study of the efficacy of acrylic bone cement loaded with supplementary amounts of gentamicin: Effect on mechanical properties, antibiotic release, and biofilm formation
    • Dunne N, Hill J, McAfee P, et al. In vitro study of the efficacy of acrylic bone cement loaded with supplementary amounts of gentamicin: effect on mechanical properties, antibiotic release, and biofilm formation. Acta Orthop. 2007;78(6): 774-785.
    • (2007) Acta Orthop , vol.78 , Issue.6 , pp. 774-785
    • Dunne, N.1    Hill, J.2    McAfee, P.3
  • 63
    • 33846005185 scopus 로고    scopus 로고
    • Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines
    • Duewelhenke N, Krut O, Eysel P. Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. Antimicrob Agents Chemother. 2007;51(1):54-63.
    • (2007) Antimicrob Agents Chemother , vol.51 , Issue.1 , pp. 54-63
    • Duewelhenke, N.1    Krut, O.2    Eysel, P.3
  • 64
    • 84859438815 scopus 로고    scopus 로고
    • The in vitro effects of antibiotics on cell viability and gene expression of equine bone marrow-derived mesenchymal stromal cells
    • Parker RA, Clegg PD, Taylor SE. The in vitro effects of antibiotics on cell viability and gene expression of equine bone marrow-derived mesenchymal stromal cells. Equine Vet J. 2012;44(3):355-360.
    • (2012) Equine Vet J , vol.44 , Issue.3 , pp. 355-360
    • Parker, R.A.1    Clegg, P.D.2    Taylor, S.E.3
  • 66
    • 78149470032 scopus 로고    scopus 로고
    • Antimicrobial properties of chitosan and mode of action: A state of the art review
    • Kong M, Chen XG, Xing K, Park HJ. Antimicrobial properties of chitosan and mode of action: a state of the art review. Int J Food Microbiol. 2010;144(1):51-63.
    • (2010) Int J Food Microbiol , vol.144 , Issue.1 , pp. 51-63
    • Kong, M.1    Chen, X.G.2    Xing, K.3    Park, H.J.4
  • 68
    • 77950949287 scopus 로고    scopus 로고
    • Demonstration of antibiofilm and antifungal efficacy of chitosan against candidal biofilms, using an in vivo central venous catheter model
    • Martinez LR, Mihu MR, Tar M, et al. Demonstration of antibiofilm and antifungal efficacy of chitosan against candidal biofilms, using an in vivo central venous catheter model. J Infect Dis. 2010;201(9):1436-1440.
    • (2010) J Infect Dis , vol.201 , Issue.9 , pp. 1436-1440
    • Martinez, L.R.1    Mihu, M.R.2    Tar, M.3
  • 69
    • 2442581210 scopus 로고    scopus 로고
    • The characteristics of a hydroxyapatite-chitosan-PMMA bone cement
    • Kim SB, Kim YJ, Yoon TL, et al. The characteristics of a hydroxyapatite-chitosan-PMMA bone cement. Biomaterials. 2004;25(26):5715-5723.
    • (2004) Biomaterials , vol.25 , Issue.26 , pp. 5715-5723
    • Kim, S.B.1    Kim, Y.J.2    Yoon, T.L.3
  • 70
    • 29244474072 scopus 로고    scopus 로고
    • Antibacterial and mechanical properties of bone cement impregnated with chitosan nanoparticles
    • Shi ZL, Neoh KG, Kang ET, Wang W. Antibacterial and mechanical properties of bone cement impregnated with chitosan nanoparticles. Biomaterials. 2006;27(11):2440-2449.
    • (2006) Biomaterials , vol.27 , Issue.11 , pp. 2440-2449
    • Shi, Z.L.1    Neoh, K.G.2    Kang, E.T.3    Wang, W.4
  • 71
    • 0001058588 scopus 로고    scopus 로고
    • Synthesis of chitosan derivatives with quaternary ammonium salt and their antibacterial activity
    • Kim CH, Choi JW, Chun HJ, Chio KS. Synthesis of chitosan derivatives with quaternary ammonium salt and their antibacterial activity. Polym Bull. 1997;38(4):387-393.
    • (1997) Polym Bull , vol.38 , Issue.4 , pp. 387-393
    • Kim, C.H.1    Choi, J.W.2    Chun, H.J.3    Chio, K.S.4
  • 72
    • 77953325570 scopus 로고    scopus 로고
    • Adjustment of the antibacterial activity and biocompatibility of hydroxypropyltrimethyl ammonium chloride chitosan by varying the degree of substitution of quaternary ammonium
    • Peng ZX, Wang L, Du L, Guo SR, Wang XQ, Tang TT. Adjustment of the antibacterial activity and biocompatibility of hydroxypropyltrimethyl ammonium chloride chitosan by varying the degree of substitution of quaternary ammonium. Carbohydr Polym. 2010;81(2):275-283.
    • (2010) Carbohydr Polym , vol.81 , Issue.2 , pp. 275-283
    • Peng, Z.X.1    Wang, L.2    Du, L.3    Guo, S.R.4    Wang, X.Q.5    Tang, T.T.6
  • 73
    • 78751692775 scopus 로고    scopus 로고
    • Quaternized chitosan inhibits icaA transcription and biofilm formation by Staphylococcus on a titanium surface
    • Peng ZX, Tu B, Shen Y, et al. Quaternized chitosan inhibits icaA transcription and biofilm formation by Staphylococcus on a titanium surface. Antimicrob Agents Chemother. 2011; 55(2):860-866.
    • (2011) Antimicrob Agents Chemother , vol.55 , Issue.2 , pp. 860-866
    • Peng, Z.X.1    Tu, B.2    Shen, Y.3
  • 74
    • 80055103251 scopus 로고    scopus 로고
    • The use of quaternised chitosan-loaded PMMA to inhibit biofilm formation and downregulate the virulence-associated gene expression of antibiotic-resistant staphylococcus
    • Tan HL, Peng ZX, Li QT, Xu XF, Guo SR, Tang TT. The use of quaternised chitosan-loaded PMMA to inhibit biofilm formation and downregulate the virulence-associated gene expression of antibiotic-resistant staphylococcus. Biomaterials. 2012;33(2):365-377.
    • (2012) Biomaterials , vol.33 , Issue.2 , pp. 365-377
    • Tan, H.L.1    Peng, Z.X.2    Li, Q.T.3    Xu, X.F.4    Guo, S.R.5    Tang, T.T.6
  • 75
    • 84862816064 scopus 로고    scopus 로고
    • Physical characterization and osteogenic activity of the quaternized chitosan-loaded PMMA bone cement
    • Tan HL, Guo SR, Yang SB. XU XF, Tang TT. Physical characterization and osteogenic activity of the quaternized chitosan-loaded PMMA bone cement. Acta Biomater. 2012; 8(6):2166-2174.
    • (2012) Acta Biomater , vol.8 , Issue.6 , pp. 2166-2174
    • Tan, H.L.1    Guo, S.R.2    Yang, S.B.3    Xu, X.F.4    Tang, T.T.5


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