The use of quaternised chitosan-loaded PMMA to inhibit biofilm formation and downregulate the virulence-associated gene expression of antibiotic-resistant staphylococcus

Biomaterials

Volumn 33, Issue 2, 2012, Pages 365-377

  Tan, Honglue ^a   Peng, Zhaoxiang ^a   Li, Qingtian ^b   Xu, Xiaofen ^c   Guo, Shengrong ^c   Tang, Tingting ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Antibiotic resistant staphylococcus; Biofilm formation; Ica genes; MecA genes; PMMA bone cement; Quaternised chitosan

Indexed keywords

ANTIBIOTIC-RESISTANT STAPHYLOCOCCUS; BIOFILM FORMATION; MECA GENES; PMMA BONE CEMENT; QUATERNISED CHITOSAN;

AMMONIUM COMPOUNDS; ANTIBIOTICS; BACTERIA; BACTERIOLOGY; BIOCHEMISTRY; BIOCOMPATIBILITY; BIOFILMS; BIOLOGICAL MATERIALS; BONE; CATALYSTS; CELL ADHESION; CEMENTS; CHITOSAN; CHLORINE COMPOUNDS; CONFOCAL MICROSCOPY; ENCODING (SYMBOLS); ENZYMES; GENE EXPRESSION; POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY;

BONE CEMENT;

BONE CEMENT; CHITOSAN; GENTAMICIN; HYDROXYPROPYLTRIMETHYL AMMONIUM CHLORIDE CHITOSAN; PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 2A; POLY(METHYL METHACRYLATE); UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BIOCOMPATIBILITY; BIOFILM; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OSTEOBLAST; PHENOTYPE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; STAPHYLOCOCCUS; STAPHYLOCOCCUS EPIDERMIDIS; SYNTHESIS;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BIOCOMPATIBLE MATERIALS; BIOFILMS; BONE CEMENTS; CHITOSAN; DOWN-REGULATION; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; GENTAMICINS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, CONFOCAL; POLYMETHYL METHACRYLATE; REAL-TIME POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS EPIDERMIDIS; UP-REGULATION;

BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 80055103251     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.09.084     Document Type: Article

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