Antibiotic-loaded cement in total hip replacement: Current indications, efficacy, and complications

Orthopedics

Volumn 28, Issue 8 SUPPL., 2005, Pages

  Jiranek, William ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BONE CEMENT; CEFAZOLIN; CIPROFLOXACIN; CLINDAMYCIN; GENTAMICIN; POLY(METHYL METHACRYLATE); TOBRAMYCIN; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BONE TURNOVER; COMPRESSIVE STRENGTH; DRUG HYPERSENSITIVITY; ELUTION; HIGH RISK PATIENT; HUMAN; INDIVIDUALIZATION; MEDICAL DECISION MAKING; NONHUMAN; PATIENT CARE; PATIENT SELECTION; POSTOPERATIVE COMPLICATION; PROPHYLAXIS; PROSTHESIS FIXATION; PROSTHESIS INFECTION; REOPERATION; RISK BENEFIT ANALYSIS; SERUM BACTERICIDAL ACTIVITY; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; TOTAL HIP PROSTHESIS; TOTAL KNEE REPLACEMENT; TREATMENT INDICATION; TREATMENT OUTCOME;

EID: 23844526233     PISSN: 01477447     EISSN: None     Source Type: Journal    
DOI: 10.3928/0147-7447-20050802-14     Document Type: Article

References (54)

1. Buchholz HW, Engelbrecht H. Depot effects of various antibiotics mixed with Palacos resins. Chirurg. 1970; 41:511-515.
2. Buchholz HW, Gartmann HD. Infection prevention and surgical management of deep insidious infection in total endoprosthesis. Chirurg. 1972; 43:446-453.
3. Wahlig H, Buchholz HW. Experimental and clinical studies on the release of gentamicin from bone cement. Chirurg. 1972; 43:441-445.
4. Jackson WO, Schmalzried TP. Limited role of direct exchange arthroplasty in the treatment of infected total hip replacements. Clin Orthop. 2000; 381:101-105.
5. Heck D, Rosenberg A, Schink-Ascani M, Garbus S, Kiewitt T. Use of antibiotic-impregnated cement during hip and knee arthroplasty in the United States. J Arthroplasty. 1995; 10:470-475.
6. Fish DN, Hoffman HM, Danziger LH. Antibiotic-impregnated cement use in U.S. hospitals. Am J Hosp Pharm. 1992; 49:2469-2474.
7. Masri BA, Duncan CP, Beauchamp CP. Long-term elution of antibiotics from bone-cement: an in vivo study using the prosthesis of antibiotic-loaded acrylic cement (PROSTALAC) system. J Arthroplasty. 1998; 13:331-338.
8. Hanssen AD, Rand JA, Osmon DR. Treatment of the infected total knee arthroplasty with insertion of another prosthesis. The effect of antibiotic-impregnated bone cement. Clin Orthop. 1994; 309:44-55.
9. Buchholz HW, Elson RA, Engelbrecht E, Lodenkamper H, Rottger J, Siegel A. Management of deep infection of total hip replacement. J Bone Joint Surg Br. 1981; 63:342-353.
10. Raut VV, Siney PD, Wroblewski BM. One-stage revision of total hip arthroplasty for deep infection. Long-term followup. Clin Orthop. 1995; 321:202-207.
11. Lieberman JR, Callaway GH, Salvati EA, Pellicci PM, Brause BD. Treatment of the infected total hip arthroplasty with a two-stage reimplantation protocol. Clin Orthop. 1994; 301:205-212.
12. Garvin KL, Hanssen AD. Infection after total hip arthroplasty. Past, present, and future. J Bone Joint Surg Am. 1995; 77:1576-1588.
13. Wentworth SJ, Masri BA, Duncan CP, Southworth CB. Hip prosthesis of antibiotic-loaded acrylic cement for the treatment of infections following total hip arthroplasty. J Bone Joint Surg Am. 2002; 84 (Suppl):123-128.
14. Younger AS, Duncan CP, Masri BA, McGraw RW. The outcome of two-stage arthroplasty using a custom-made interval spacer to treat the infected hip. J Arthroplasty. 1997; 12:615-623.
15. Buchholz HW, Elson RA, Heinert K. Antibiotic-loaded acrylic cement: current concepts. Clin Orthop. 1984; 190:96-108.
16. Lynch M, Esser MP, Shelley P, Wroblewski BM. Deep infection in Charnley low-friction arthroplasty. Comparison of plain and gentamicin-loaded cement. J Bone Joint Surg Br. 1987; 69:355-360.
17. Josefsson Q Gudmundsson G, Kolmert L, Wijkstrom S. Prophylaxis with systemic antibiotics versus gentamicin bone cement in total hip arthroplasty. A five-year survey of 1688 hips. Clin Orthop. 1990; 253:173-178.
18. Josefsson G, Kolmert L. Prophylaxis with systematic antibiotics versus gentamicin bone cement in total hip arthroplasty. A ten-year survey of 1,688 hips. Clin Orthop. 1993; 292:210-214.
19. Persson U, Persson M, Malchau H. The economics of preventing revisions in total hip replacement. Acta Orthop Scand. 1999; 70:163-169.
20. Chiu FY, Chen CM, Lin CF, Lo WH. Cefuroxime-impregnated cement in primary total knee arthroplasty: a prospective, randomized study of three hundred and forty knees. J Bone Joint Surg Am. 2002; 84:759-762.
21. Chiu FY, Lin CF, Chen CM, Lo WH, Chaung TY. Cefuroxime-impregnated cement at primary total knee arthroplasty in diabetes mellitus. A prospective, randomised study. J Bone Joint Surg Br. 2001; 83:691-695.
22. del Real RP, Padilla S, Vallet-Regi M. Gentamicin release from hydroxyapatite/poly(ethyl methacrylate)/poly(methyl methacrylate)composites. J Biomed Mater Res. 2000; 52:1-7.
23. Powles JW, Spencer RF, Lovering AM. Gentamicin release from old cement during revision hip arthroplasty. J Bone Joint Surg Br. 1998; 80:607-610.
24. Brien WW, Salvati EA, Klein R, Brause B, Stern S. Antibiotic impregnated bone cement in total hip arthroplasty. An in vivo comparison of the clution properties of tobramycin and vancomycin. Clin Orthop. 1993; 296:242-248.
25. Baker AS, Greenham LW. Release of gentamicin from acrylic bone cement. Elution and diffusion studies. J Bone Joint Surg Am. 1988; 70:1551-1557.
26. Waertel G. The role of antibiotic-loaded cement in the treatment of an infection after a hip replacement. J Bone Joint Surg Am. 1996; 78:472-473.
27. Duncan CP, Masri BA. The role of antibiotic-loaded cement in the treatment of an infection after a hip replacement. Instr Course Lect. 1995; 44:305-313.
28. Tunney MM, Patrick S, Gorman SP, et al. Antimicrobial susceptibility of bacteria isolated from orthopedic implants following revision hip surgery. Antimicrob Agents Chemother. 1998; 42:3002-3006.
29. Adams K, Couch L, Cierny G, Calhoun J, Mader JT. In vitro and in vivo evaluation of antibiotic diffusion from antibiotic-impregnated polymethylmethacrylate beads. Clin Orthop. 1992; 244-252.
30. Baleani M, Cristofolini L, Minari C, Toni A. Fatigue strength of PMMA bone cement mixed with gentamicin and barium sulphate vs pure PMMA. Proc Inst Mech Eng [H]. 2003; 217:9-12.
31. Davies JP, Harris WH. Effect of hand mixing tobramycin on the fatigue strength of Simplex P. J Biomed Mater Res. 1991; 25:1409-1414.
32. Davies JP, O'Connor DO, Burke DW, Harris WH. Influence of antibiotic impregnation on the fatigue life of Simplex P and Palacos R acrylic bone cements, with and without centrifugation. J Biomed Mater Res. 1989; 23:379-397.
33. Bargar WL, Martin RB, deJesus R, Madison MT. The addition of tobramycin to contrast bone cement. Effect on flexural strength. J Arthroplasty. 1986; 1:165-168.
34. Gogus A, Akman S, Goksan SB, Bozdag E. [Mechanical strength of antibiotic-impregnated bone cement on Day 0 and Day 15: a biomechanical study with Surgical Simplex P and teicoplanin]. Acta Orthop Traumatol Turc. 2002; 36:63-71.
35. He Y, Trotignon JP, Loty B, Tcharkhtchi A, Verdu J. Effect of antibiotics on the properties of poly(methylmethacrylate)-based bone cement. Biomed Mater Res. 2002; 63:800-806.
36. Lautenschlager EP, Jacobs JJ, Marshall GW, Meyer PR Jr. Mechanical properties of bone cements containing large doses of antibiotic powders. J Biomed Mater Res. 1976; 10:929-938.
37. Lautenschlager EP, Marshall GW, Marks KE, Schwartz J, Nelson CL. Mechanical strength of acrylic bone cements impregnated with antibiotics. J Biomed Mater Res. 1976; 10:837-845.
38. Askew MJ, Kufel MF, Fleissner PR Jr, Gradisar IA Jr, Salstrom SJ, Tan JS. Effect of vacuum mixing on the mechanical properties of antibiotic-impregnated polymethylmethacrylate bone cement. J Biomed Mater Res. 1990; 24:573-580.
39. Chohfi M, Langlais F, Fourastier J, Minet J, Thomazeau H, Cormier M. Pharmacokinetics, uses, and limitations of vancomycin-loaded bone cement. Int Orthop. 1998; 22:171-177.
40. Pritchett JW, Bortel DT. Tobramycin-impregnated cement in total hip replacements. Orthop Rev. 1992; 21:577-579.
41. Petersen BH, Steimel LA, Black HR. Immunological responsiveness of guinea pigs to antibiotics diffusing from bone cement. Antimicrob Agents Chemother. 1982; 22:704-706.
42. Pedersen JG, Lund B. Effects of gentamicin and monomer on bone. An in vitro study. J Arthroplasty. 1988; 3 (Suppl):S63-S68.
43. Isefuku S, Joyner CJ, Simpson AH. Gentamicin may have an adverse effect on osteogenesis. J Orthop Trauma. 2003; 17:212-216.
44. Kendall RW, Duncan CP, Smith JA, Ngui-Yen JH. Persistence of bacteria on antibiotic loaded acrylic depots. A reason for caution. Clin Orthop. 1996; 329:273-280.
45. Hope PG, Kristinsson KG, Norman P, Elson RA. Deep infection of cemented total hip arthroplasties caused by coagulase-negative staphylococci. J Bone Joint Surg Br. 1989; 71:851-855.
46. Weber FA, Lautenbach EE. Revision of infected total hip arthroplasty. Clin Orthop. 1986; 211:108-115.
47. Neut D, van de Belt H, Stokroos I, van Horn JR, van der Mei HC, Busscher HJ. Biomaterial-associated infection of gentamicin-loaded PMMA beads in orthopaedic revision surgery. J Antimicrob Chemother. 2001; 47:885-891.
48. Thomes B, Murray P, Bouchier-Hayes D. Development of resistant strains of Staphylococcus epidermidis on gentamicin-loaded bone cement in vivo. J Bone Joint Surg Br. 2002; 84:758-760.
49. Naylor PT, Myrvik QN, Gristina A. Antibiotic resistance of biomaterial-adherent coagulase-negative and coagulase-positive staphylococci. Clin Orthop. 1990; 261:126-133.
50. Wininger DA, Fass RJ. Antibiotic-impregnated cement and beads for orthopedic infections. Antimicrob Agents Chemother. 1996; 40:2675-2679.
51. Arciola CR, Campoccia D, Montanaro L. Effects on antibiotic resistance of Staphylococcus epidermidis following adhesion to polymethylmethacrylate and to silicone surfaces. Biomaterials. 2002; 23:1495-1502.
52. Chandra J, Kuhn DM, Mukherjee PK, Hoyer LL, McCormick T, Ghannoum MA. Biofilm formation by the fungal pathogen Candida albicans: development, architecture, and drug resistance. J Bacteriol. 2001; 183:5385-5394.
53. Montanaro L, Cavedagna D, Baldassarri L, Arciola CR. Adhesion of a Staphylococcus aureus strain to biomaterials does not select methicillin-resistant mutants. New Microbiol. 2001; 24:57-61.
54. Tunney MM, Ramage G, Patrick S, Nixon JR, Murphy PG, Gorman SP. Antimicrobial susceptibility of bacteria isolated from orthopedic implants following revision hip surgery. Antimicrob Agents Chemother. 1998; 42:3002-3005.