Antibiotic Bone Cement and the Incidence of Deep Infection after Total Knee Arthroplasty

Journal of Arthroplasty

Volumn 24, Issue 7, 2009, Pages 1015-1018

  Gandhi, Rajiv ^a   Razak, Fahad ^a,b   Pathy, Rubini ^a   Davey, J Roderick ^a   Syed, Khalid ^a   Mahomed, Nizar N ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

antibiotic cement; infection; knee arthroplasty; prophylaxis

Indexed keywords

ANTIBIOTIC BONE CEMENT; BONE CEMENT; UNCLASSIFIED DRUG;

ADULT; AGED; ARTHRALGIA; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; INCIDENCE; INFECTION CONTROL; INTERMETHOD COMPARISON; KNEE OSTEOARTHRITIS; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE INFECTION; RHEUMATOID ARTHRITIS; TOTAL KNEE REPLACEMENT;

AGED; ANTI-BACTERIAL AGENTS; ARTHROPLASTY, REPLACEMENT, KNEE; BONE CEMENTS; DRUG DELIVERY SYSTEMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; LINEAR MODELS; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; PROSTHESIS-RELATED INFECTIONS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 70349236021     PISSN: 08835403     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arth.2008.08.004     Document Type: Article

References (27)

1. Rorabeck C.H. Session IV: salvage of the infected total knee replacement. Clin Orthop Rel Res 404 (2002) 113
2. Bourne R.B. Prophylactic use of antibiotic bone cement: an emerging standard-in the affirmative. J Arthroplasty 19 Suppl 4 (2004) 69
3. Peersman G., Laskin R., Davis J., et al. Infection in total knee replacement: a retrospective review of 6489 total knee replacements. Clin Orthop Rel Res 392 (2001) 15
4. Meding J.B., Keating E.M., Ritter M.A., et al. Long-term followup of posterior-cruciate-retaining TKR in patients with rheumatoid arthritis. Clin Orthop Relat Res 428 (2004) 146
5. Sharma S., Nicol F., Hullin M.G., et al. Long-term results of the uncemented low contact stress total knee replacement in patients with rheumatoid arthritis. J Bone Joint Surg Br 87 (2005) 1077
6. Amenabar P.P., Carrion M., Apablaza D., et al. Total knee arthroplasty in patients with rheumatoid arthritis. Rev Med Chile 132 (2004) 337 [Spanish]
7. Kurtz S., Lau E., Schmier J., et al. Nationwide infection burden in revision hip and knee arthroplasty. Trans Orthop Res Soc 31 (2006) 179
8. Kurtz S., Ong K.L., Schmier J., et al. Future clinical and economic impact of revision total hip and knee arthroplasty. J Bone Joint Surg Am 89 (2007) 144
9. Heck D., Rosenberg A., Schink-Ascani M., et al. Use of antibiotic impregnated cement during hip and knee arthroplasty in the United States. J Arthroplasty 10 (1995) 470
10. Sculco T.P. The economic impact of infected total joint arthroplasty. Instr Course Lect 42 (1993) 349
11. Chiu F.Y., Lin C.F., Chen C.M., et al. Cefuroxime-impregnated cement at primary total knee arthroplasty in diabetes mellitus. J Bone Joint Surg Br 83-B (2001) 691
12. Chiu F.Y., Chen C.M., Lin C.F., et al. Cefuroxime-impregnated cement in primary total knee arthroplasty: a prospective, randomized study of three hundred and forty knees. J Bone Joint Surg Br 84 (2002) 759
13. Hanssen A.D. Prophylactic use of antibiotic bone cement: an emerging standard-in opposition. J Arthroplasty 19 S4 (2004) 73
14. Horan T.C., Gaynes R.P., Martone W.J., et al. CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 13 (1992) 606
15. Charlson M., Pompei P., Ales K.L., et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40 (1987) 373
16. Bellamy N., Buchanan W.W., Goldsmith C.H., et al. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 5 (1988) 1833
17. Jiranek W.A., Hanssen A.D., and Greenwald A.S. Antibiotic-loaded bone cement for infection prophylaxis in total joint replacement. J Bone Joint Surg Am 88 (2006) 2487
18. Yang K., Yeo S.J., Lee B.P., et al. Total knee arthroplasty in diabetic patients: a study of 109 consecutive cases. J Arthroplasty 16 (2001) 102
19. England S.P., Stern S.H., Insall J.N., et al. Total knee arthroplasty in diabetes mellitus. Clin Orthop Relat Res 260 (1990) 130
20. Meding J.B., Reddleman K., Keating M.E., et al. Total knee replacement in patients with diabetes mellitus. Clin Orthop Relat Res 416 (2003) 208
21. Blom A.W., Brown J., Taylor A.H., et al. Infection after total knee arthroplasty. J Bone Joint Surg Br 86 (2004) 688
22. Arciola C.R., Campoccia D., and Montanaro L. Effects on antibiotic resistance of Staphylococcus epidermidis following adhesion to polymethylmethacrylate and to silicone surfaces. Biomaterials 6 (2002) 1495
23. Joseph T.N., Chen A.L., and Di Cesare P.E. Use of antibiotic impregnated cement in total joint arthroplasty. J Am Acad Orthop Surg 11 (2003) 38
24. Davies J.P., and Harris W.H. Effect of hand mixing tobramycin on the fatigue strength of Simplex P. J Biomed Mater Res 25 (1991) 1409
25. Masari B.A., Duncan C.P., and Beauchamp C.P. Long-term elution of antibiotics from bone cement: an in vivo study using the prosthesis of antibiotic-loaded acrylic cement (PROSTALAC) system. J Arthroplasty 13 (1998) 331
26. Adelberth G., Nilsson K.G., Karrholm J., et al. Fixation of the tibial component using CMW-1 or Palacos bone cement with gentamicin: similar outcome in a randomized radiostereometric study of 51 total knee arthroplasties. Acta Orthop Scand 73 (2002) 531
27. Davies J.P., O'Connor D.O., Burke D.W., et al. Influence of antibiotic impregnation on the fatigue life of Simplex P and Palacos R acrylic bone cements, with and without centrifugation. J Biomed Mater Res 23 (1989) 379