-
1
-
-
84870477503
-
-
Statistics Canada. Morality
-
Statistics Canada. Morality, Summary List of Causes 2008. 2011.
-
(2008)
Summary List of Causes
, vol.2011
-
-
-
2
-
-
0028941640
-
Adenovirus e1a represses cardiac gene transcription and reactivates dna synthesis in ventricular myocytes, via alternative pocket protein-and p300-binding domains
-
Kirshenbaum LA, Schneider MD. Adenovirus E1A represses cardiac gene transcription and reactivates DNA synthesis in ventricular myocytes, via alternative pocket protein-and p300-binding domains. J Biol Chem. 1995;270:7791-4.
-
(1995)
J Biol Chem
, vol.270
, pp. 7791-4
-
-
Kirshenbaum, L.A.1
Schneider, M.D.2
-
3
-
-
0030296944
-
Human e2f-1 reactivates cell cycle progression in ventricular myocytes and represses cardiac gene transcription
-
Kirshenbaum LA, Abdellatif M, Chakraborty S, Schneider MD. Human E2F-1 reactivates cell cycle progression in ventricular myocytes and represses cardiac gene transcription. Dev Biol. 1996;179(2):402-11.
-
(1996)
Dev Biol
, vol.179
, Issue.2
, pp. 402-11
-
-
Kirshenbaum, L.A.1
Abdellatif, M.2
Chakraborty, S.3
Schneider, M.D.4
-
4
-
-
0029591255
-
The cardiac cell cycle, pocket proteins, and p300
-
Kirshenbaum LA, Schneider MD. The cardiac cell cycle, pocket proteins, and p300. Trends Cardiovasc Med. 1995;5(6):230-5.
-
(1995)
Trends Cardiovasc Med
, vol.5
, Issue.6
, pp. 230-5
-
-
Kirshenbaum, L.A.1
Schneider, M.D.2
-
6
-
-
11144287220
-
Apoptosis of ventricular myocytes: A means to an end
-
Regula KM, Kirshenbaum LA. Apoptosis of ventricular myocytes: a means to an end. J Mol Cell Cardiol. 2005;38(1):3-13.
-
(2005)
J Mol Cell Cardiol
, vol.38
, Issue.1
, pp. 3-13
-
-
Regula, K.M.1
Kirshenbaum, L.A.2
-
7
-
-
0032848297
-
Linkage of the bh4 domain of bcl-2 and the nuclear factor kappab signaling pathway for suppression of apoptosis
-
de Moissac D, Zheng H, Kirshenbaum LA. Linkage of the BH4 domain of Bcl-2 and the nuclear factor kappaB signaling pathway for suppression of apoptosis. J Biol Chem. 1999;274(41):29505-9.
-
(1999)
J Biol Chem
, vol.274
, Issue.41
, pp. 29505-9
-
-
De Moissac, D.1
Zheng, H.2
Kirshenbaum, L.A.3
-
8
-
-
43949128077
-
Molecular regulation of autophagy and apoptosis during ischemic and non-ischemic cardiomyopathy
-
Shaw J, Kirshenbaum LA. Molecular regulation of autophagy and apoptosis during ischemic and non-ischemic cardiomyopathy. Autophagy. 2008;4(4):427-34.
-
(2008)
Autophagy
, vol.4
, Issue.4
, pp. 427-34
-
-
Shaw, J.1
Kirshenbaum, L.A.2
-
9
-
-
0034057320
-
Apoptosis in cancer
-
Lowe SW, Lin AW. Apoptosis in cancer. Carcinogenesis. 2000;21 (3):485-95.
-
(2000)
Carcinogenesis
, vol.21
, Issue.3
, pp. 485-95
-
-
Lowe, S.W.1
Lin, A.W.2
-
10
-
-
0034329742
-
Apoptosis in neurodegenerative disorders
-
Mattson MP. Apoptosis in neurodegenerative disorders. Nat Rev Mol Cell Biol. 2000;1(2):120-9.
-
(2000)
Nat Rev Mol Cell Biol
, vol.1
, Issue.2
, pp. 120-9
-
-
Mattson, M.P.1
-
11
-
-
79960329587
-
Mechanisms and inhibitors of apoptosis in cardiovascular diseases
-
Recent review highlighting the apoptotic pathways associated with heart failure
-
Singh SS, Kang PM. Mechanisms and inhibitors of apoptosis in cardiovascular diseases. Curr Pharm Des. 2011;17(18):1783-93. Recent review highlighting the apoptotic pathways associated with heart failure.
-
(2011)
Curr Pharm Des
, vol.17
, Issue.18
, pp. 1783-93
-
-
Singh, S.S.1
Kang, P.M.2
-
12
-
-
67249103815
-
-
3rd ed. Philadelphia: Mosby/Elsevier
-
Recent review highlighting the apoptotic pathways associated with heart failure. 13. Goljan E. Rapid review pathology. 3rd ed. Philadelphia: Mosby/Elsevier; 2010.
-
Rapid Review Pathology
, pp. 2010
-
-
Goljan, E.1
-
14
-
-
78649634982
-
Genetic control of necrosis -Another type of programmed cell death
-
McCall K. Genetic control of necrosis -another type of programmed cell death. Curr Opin Cell Biol. 2010;22:882-8.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 882-8
-
-
McCall, K.1
-
15
-
-
77956179625
-
Regulation of macroautophagy in saccharomyces cerevisiae
-
Inoue Y, Klionsky DJ. Regulation of macroautophagy in Saccharomyces cerevisiae. Semin Cell Dev Biol. 2010;21(7):664-70.
-
(2010)
Semin Cell Dev Biol
, vol.21
, Issue.7
, pp. 664-670
-
-
Inoue, Y.1
Klionsky, D.J.2
-
16
-
-
67649467294
-
Dynamics and diversity in autophagy mechanisms: Lessons from yeast
-
Nakatogawa H, Suzuki K, Kamada Y, Ohsumi Y. Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nat Rev Mol Cell Biol. 2009;10(7):458-67.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.7
, pp. 458-67
-
-
Nakatogawa, H.1
Suzuki, K.2
Kamada, Y.3
Ohsumi, Y.4
-
18
-
-
0027424777
-
Isolation and characterization of autophagy-defective mutants of saccharomyces cerevisiae
-
Tsukada M, Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 1993;333(1-2):169-74.
-
(1993)
FEBS Lett
, vol.333
, Issue.1-2
, pp. 169-74
-
-
Tsukada, M.1
Ohsumi, Y.2
-
19
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
Kuma A, Hatano M, Matsui M, et al. The role of autophagy during the early neonatal starvation period. Nature. 2004;32(7020):1032-6.
-
(2004)
Nature
, vol.32
, Issue.7020
, pp. 1032-6
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
-
20
-
-
33744536558
-
Urocortin inhibits beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury
-
Valentim L, Laurence KM, Townsend PA, et al. Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury. J Mol Cell Cardiol. 2006;40 (6):846-52.
-
(2006)
J Mol Cell Cardiol
, vol.40
, Issue.6
, pp. 846-52
-
-
Valentim, L.1
Laurence, K.M.2
Townsend, P.A.3
-
21
-
-
79956126271
-
Oxidative stress stimulates autophagic flux during ischemia/reperfusion
-
Hariharan N, Zhai P, Sadoshima J. Oxidative stress stimulates autophagic flux during ischemia/reperfusion. Antioxid Redox Signal. 2011;14(11):2179-90.
-
(2011)
Antioxid Redox Signal
, vol.14
, Issue.11
, pp. 2179-90
-
-
Hariharan, N.1
Zhai, P.2
Sadoshima, J.3
-
22
-
-
33745816360
-
Autophagic degeneration and death of cardiomyocytes in heart failure
-
Takemura G, Miyata S, Kawase Y, et al. Autophagic degeneration and death of cardiomyocytes in heart failure. Autophagy. 2006;2 (3):212-4.
-
(2006)
Autophagy
, vol.2
, Issue.3
, pp. 212-4
-
-
Takemura, G.1
Miyata, S.2
Kawase, Y.3
-
23
-
-
32244442749
-
Functional specificity of the mammalian beclin-vps34 pi 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking
-
Zeng X, Overmeyer JH, Maltese WA. Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking. J Cell Sci. 2006;19(Pt 2):259-70.
-
(2006)
J Cell Sci
, vol.19
, Issue.PART 2
, pp. 259-70
-
-
Zeng, X.1
Overmeyer, J.H.2
Maltese, W.A.3
-
24
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit beclin 1-dependent autophagy
-
Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell. 2005;122(6):927-39.
-
(2005)
Cell
, vol.122
, Issue.6
, pp. 927-39
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
-
25
-
-
61849102389
-
Dap-kinase-mediated phosphorylation on the bh3 domain of beclin 1 promotes dissociation of beclin 1 from bcl-xl and induction of autophagy
-
Zalckvar E, Berissi H, Mizrachy L, et al. DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy. EMBO Rep. 2009;10(3):285-92.
-
(2009)
EMBO Rep
, vol.10
, Issue.3
, pp. 285-92
-
-
Zalckvar, E.1
Berissi, H.2
Mizrachy, L.3
-
26
-
-
83555168258
-
Inhibition of autophagy by tab2 and tab3
-
Criollo A, Niso-Santano M, Malik SA, et al. Inhibition of autophagy by TAB2 and TAB3. EMBO J. 2011;30(24):4908-20.
-
(2011)
EMBO J
, vol.30
, Issue.24
, pp. 4908-20
-
-
Criollo, A.1
Niso-Santano, M.2
Malik, S.A.3
-
27
-
-
79953230490
-
Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis. Protein cell. 2010;1(5):468-77. Recent study highlighting the cross talk between autophagy and apoptosis. 29. Kerr jfr. History of the events leading to the formulation of the apoptosis concept
-
Zhu Y, Zhao L, Liu L, et al. Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis. Protein Cell. 2010;1(5):468-77. Recent study highlighting the cross talk between autophagy and apoptosis. 29. Kerr JFR. History of the events leading to the formulation of the apoptosis concept. Toxicology. 2002;181-182:471-4.
-
(2002)
Toxicology
, vol.181-182
, pp. 471-4
-
-
Zhu, Y.1
Zhao, L.2
Liu, L.3
-
28
-
-
77956938316
-
A model to die for: Signaling to apoptotic cell removal in worm, fly and mouse
-
Kinchen JM. A model to die for: signaling to apoptotic cell removal in worm, fly and mouse. Apoptosis. 2010;15(9):998-1006.
-
(2010)
Apoptosis
, vol.15
, Issue.9
, pp. 998-1006
-
-
Kinchen, J.M.1
-
29
-
-
0036167347
-
Interdigital apoptosis and downregulation of bag-1 expression in mouse autopods
-
Crocoll A, Herzer U, Ghyselinck NB, et al. Interdigital apoptosis and downregulation of BAG-1 expression in mouse autopods. Mech Dev. 2002;111(1-2):149-52.
-
(2002)
Mech Dev
, vol.111
, Issue.1-2
, pp. 149-52
-
-
Crocoll, A.1
Herzer, U.2
Ghyselinck, N.B.3
-
30
-
-
0033959317
-
Caspase activation and mitochondrial cytochrome c release during hypoxia-mediated apoptosis of adult ventricular myocytes
-
de Moissac D, Gurevich RM, Zheng H, et al. Caspase activation and mitochondrial cytochrome C release during hypoxia-mediated apoptosis of adult ventricular myocytes. J Mol Cell Cardiol. 2000;32:53-63.
-
(2000)
J Mol Cell Cardiol
, vol.32
, pp. 53-63
-
-
De Moissac, D.1
Gurevich, R.M.2
Zheng, H.3
-
31
-
-
77950950851
-
Apoptosis as a mechanism for the elimination of cardiomyocytes after acute myocardial infarction
-
Prech M, Marszalek A, Marszalek J, et al. Apoptosis as a mechanism for the elimination of cardiomyocytes after acute myocardial infarction. Am J Cardiol. 2010;105:1240-5.
-
(2010)
Am J Cardiol
, vol.105
, pp. 1240-5
-
-
Prech, M.1
Marszalek, A.2
Marszalek, J.3
-
32
-
-
50349089411
-
Dissecting apoptosis and intrinsic death pathways in the heart
-
Weidman D, Shaw J, Bednarczyk J, et al. Dissecting apoptosis and intrinsic death pathways in the heart. Methods Enzymol. 2008; 446:277-85.
-
(2008)
Methods Enzymol
, vol.446
, pp. 277-85
-
-
Weidman, D.1
Shaw, J.2
Bednarczyk, J.3
-
33
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating iap inhibition
-
Du C, Fang M, Li Y, et al. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell. 2000;102(1):33-42.
-
(2000)
Cell
, vol.102
, Issue.1
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
-
34
-
-
0034785591
-
A serine protease, htra2, is released from the mitochondria and interacts with xiap, inducing cell death
-
Suzuki Y, Imai Y, Nakayama H, et al. A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol Cell. 2001;8(3):613-21.
-
(2001)
Mol Cell
, vol.8
, Issue.3
, pp. 613-21
-
-
Suzuki, Y.1
Imai, Y.2
Nakayama, H.3
-
35
-
-
84860180832
-
Bax regulates primary necrosis through mitochondrial dynamics
-
Whelan RS, Konstantinidis K, Wei A-C, et al. Bax regulates primary necrosis through mitochondrial dynamics. Proc Natl Acad Sci USA. 2012;109(17):6566-71.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.17
, pp. 6566-71
-
-
Whelan, R.S.1
Konstantinidis, K.2
Wei, A.-C.3
-
36
-
-
84862209309
-
A bax/bak and cyclophilin d-independent intrinsic apoptosis pathway
-
Zamorano S, Rojas-Rivera D, Lisbona F, et al. A BAX/BAK and Cyclophilin D-Independent Intrinsic Apoptosis Pathway. PLoS One. 2012;7(6):e37782.
-
(2012)
PLoS One
, vol.7
, Issue.6
-
-
Zamorano, S.1
Rojas-Rivera, D.2
Lisbona, F.3
-
37
-
-
0026093190
-
Tumor necrosis factor induces apoptosis (programmed cell death) in normal endothelial cells in vitro
-
Robaye B, Mosselmans R, Fiers W, et al. Tumor necrosis factor induces apoptosis (programmed cell death) in normal endothelial cells in vitro. Am J Pathol. 1991;38(2):447-53.
-
(1991)
Am J Pathol
, vol.38
, Issue.2
, pp. 447-53
-
-
Robaye, B.1
Mosselmans, R.2
Fiers, W.3
-
38
-
-
0027145632
-
Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family
-
Suda T, Takahashi T, Golstein P, Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell. 1993;75(6):1169-78.
-
(1993)
Cell
, vol.75
, Issue.6
, pp. 1169-78
-
-
Suda, T.1
Takahashi, T.2
Golstein, P.3
Nagata, S.4
-
39
-
-
0004263083
-
-
2nd Ed. Philadelphia: Saunders/Elsevier
-
Pollard T. Cell biology. 2nd ed. Philadelphia: Saunders/Elsevier; 2008.
-
(2008)
Cell Biology
-
-
Pollard, T.1
-
40
-
-
9544246860
-
Mitochondrial permeability transition is a central coordinating event of apoptosis
-
Marchetti P, Castedo M, Susin SA, et al. Mitochondrial permeability transition is a central coordinating event of apoptosis. J Exp Med. 1996;184(3):1155-60.
-
(1996)
J Exp Med
, vol.184
, Issue.3
, pp. 1155-60
-
-
Marchetti, P.1
Castedo, M.2
Susin, S.A.3
-
41
-
-
0347065342
-
A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses
-
Chan FK-M, Shisler J, Bixby JG, et al. A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. J Biol Chem. 2003;278:51613-21.
-
(2003)
J Biol Chem
, vol.278
, pp. 51613-21
-
-
Chan, F.K.-M.1
Shisler, J.2
Bixby, J.G.3
-
42
-
-
77956051110
-
Physiological consequences of programmed necrosis an alternative form of cell demise
-
Recent review highlighting advances in programmed necrosis.
-
Cho YS, Park SY, Shin HS, Chan FK-M. Physiological consequences of programmed necrosis, an alternative form of cell demise. Mol Cells. 2010;29(4):327-32. Recent review highlighting advances in programmed necrosis.
-
(2010)
Mol Cells
, vol.29
, Issue.4
, pp. 327-32
-
-
Cho, Y.S.1
Park, S.Y.2
Shin, H.S.3
Chan, F.K.-M.4
-
43
-
-
0033942613
-
Bnip3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore
-
Vande Velde C, Cizeau J, Dubik D, et al. BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore. Mol Cell Biol. 2000;20(15):5454-68.
-
(2000)
Mol Cell Biol.
, vol.20
, Issue.15
, pp. 5454-68
-
-
Vande Velde, C.1
Cizeau, J.2
Dubik, D.3
-
44
-
-
39749123276
-
Apoptosis and necrosis: Detection, discrimination and phagocytosis
-
Krysko DV, Vanden Berghe T, D'Herde K, Vandenabeele P. Apoptosis and necrosis: detection, discrimination and phagocytosis. Methods. 2008;44:205-21.
-
(2008)
Methods
, vol.44
, pp. 205-21
-
-
Krysko, D.V.1
Vanden Berghe, T.2
D'Herde, K.3
Vandenabeele, P.4
-
45
-
-
79954606808
-
Programmed necrosis not apoptosis in the heart
-
Most recent systematic review about programmed cell death in the myocardium.
-
Kung G, Konstantinidis K, Kitsis RN. Programmed necrosis, not apoptosis, in the heart. Circ Res. 2011;108(8):1017-36. Most recent systematic review about programmed cell death in the myocardium.
-
(2011)
Circ Res.
, vol.108
, Issue.8
, pp. 1017-36
-
-
Kung, G.1
Konstantinidis, K.2
Kitsis, R.N.3
-
46
-
-
0033400542
-
Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death
-
Lemasters JJ, Qian T, Bradham CA, et al. Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death. J Bioenerg Biomembr. 1999;31:305-19.
-
(1999)
J Bioenerg Biomembr.
, vol.31
, pp. 305-19
-
-
Lemasters, J.J.1
Qian, T.2
Bradham, C.A.3
-
47
-
-
77955511922
-
Dichotomous actions of nf-kappab signaling pathways in heart
-
Recent review highlighting cell survival signaling in the heart.
-
Dhingra R, Shaw JA, Aviv Y, Kirshenbaum LA. Dichotomous actions of NF-kappaB signaling pathways in heart. J Cardiovasc Transl Res. 2010;3:344-54. Recent review highlighting cell survival signaling in the heart.
-
(2010)
J Cardiovasc Transl Res.
, vol.3
, pp. 344-54
-
-
Dhingra, R.1
Shaw, J.A.2
Aviv, Y.3
Kirshenbaum, L.A.4
-
48
-
-
33646034316
-
Activation of ikk by tnfalpha requires site-specific ubiquitination of rip1 and polyubiquitin binding by nemo
-
Ea C-K, Deng L, Xia ZP, et al. Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol Cell. 2006;22:245-57.
-
(2006)
Mol Cell.
, vol.22
, pp. 245-57
-
-
Ea, C.-K.1
Deng, L.2
Xia, Z.P.3
-
49
-
-
2442559290
-
Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-iap1 and c-iap2) in vitro
-
Park S-M, Yoon J-B, Lee TH. Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro. FEBS Lett. 2004;566:151-6.
-
(2004)
FEBS Lett
, vol.566
, pp. 151-6
-
-
Park, S.-M.1
Yoon, J.-B.2
Lee, T.H.3
-
50
-
-
72149117664
-
Traf2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis
-
Vince JE, Pantaki D, Feltham R, et al. TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis. J Biol Chem. 2009;284:35906-15.
-
(2009)
J Biol Chem
, vol.284
, pp. 35906-15
-
-
Vince, J.E.1
Pantaki, D.2
Feltham, R.3
-
51
-
-
84859602197
-
De-ubiquitinating protease USP2a targets RIP1 and TRAF2 to mediate cell death by TNF
-
Mahul-Mellier AL, Pazarentzos E, Datler C, et al. De-ubiquitinating protease USP2a targets RIP1 and TRAF2 to mediate cell death by TNF. Cell Death Differ. 2012;19(5):891-9.
-
(2012)
Cell Death Differ
, vol.19
, Issue.5
, pp. 891-9
-
-
Mahul-Mellier, A.L.1
Pazarentzos, E.2
Datler, C.3
-
52
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
-
Wertz IE, O'Rourke KM, Zhou H, et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature. 2004;430:694-9.
-
(2004)
Nature
, vol.430
, pp. 694-9
-
-
Wertz, I.E.1
O'Rourke, K.M.2
Zhou, H.3
-
53
-
-
78650915537
-
Deubiquitinases in the regulation of nf-?b signaling
-
Harhaj EW, Dixit VM. Deubiquitinases in the regulation of NF-?B signaling. Cell Res. 2011;21:22-39.
-
(2011)
Cell Res
, vol.21
, pp. 22-39
-
-
Harhaj, E.W.1
Dixit, V.M.2
-
54
-
-
0034353188
-
Activation of the ikappa b kinases by rip via ikkgamma /nemo-mediated oligomerization
-
Poyet JL, Srinivasula SM, Lin JH, et al. Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization. J Biol Chem. 2000;275:37966-77.
-
(2000)
J Biol Chem
, vol.275
, pp. 37966-77
-
-
Poyet, J.L.1
Srinivasula, S.M.2
Lin, J.H.3
-
55
-
-
79251646629
-
Stercurensin inhibits nuclear factor-?b-dependent inflammatory signals through attenuation of tak1-tab1 complex formation
-
doi:10.1002/jcb.22945
-
Kim Y-J, Kim H-C, Ko H, et al. Stercurensin inhibits nuclear factor-?B-dependent inflammatory signals through attenuation of TAK1-TAB1 complex formation. J Cell Biochem. 2010. doi:10.1002/jcb.22945
-
(2010)
J Cell Biochem
-
-
Kim, Y.-J.1
Kim, H.-C.2
Ko, H.3
-
56
-
-
11144291395
-
Nuclear factor-kappab represses hypoxia-induced mitochondrial defects and cell death of ventricular myocytes
-
Regula KM, Baetz D, Kirshenbaum LA. Nuclear factor-kappaB represses hypoxia-induced mitochondrial defects and cell death of ventricular myocytes. Circulation. 2004;110:3795-802.
-
(2004)
Circulation
, vol.110
, pp. 3795-802
-
-
Regula, K.M.1
Baetz, D.2
Kirshenbaum, L.A.3
-
57
-
-
0037099678
-
C-flip (l) is a dual function regulator for caspase-8 activation and cd95-mediated apoptosis
-
Chang DW, Xing Z, Pan Y, et al. c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. EMBO J. 2002;21(14):3704-14.
-
(2002)
EMBO J
, vol.21
, Issue.14
, pp. 3704-14
-
-
Chang, D.W.1
Xing, Z.2
Pan, Y.3
-
58
-
-
84861712290
-
Survival function of the fadd-caspase-8-cflip (l) complex
-
Dillon CP, Oberst A, Weinlich R, et al. Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep. 2012;1(5):401-7.
-
(2012)
Cell Rep.
, vol.1
, Issue.5
, pp. 401-7
-
-
Dillon, C.P.1
Oberst, A.2
Weinlich, R.3
-
59
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing cyld
-
O'Donnell MA, Perez-Jimenez E, Oberst A, et al. Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol. 2011;13(12):1437-42.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.12
, pp. 1437-42
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
-
60
-
-
79952810024
-
Catalytic activity of the caspase-8-flip(l) complex inhibits ripk3-dependent necrosis
-
Recent study showing the effect of caspase-8 catalytic activity during programmed cell death.
-
Oberst A, Dillon CP, Weinlich R, et al. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature. 2011;471(7338):363-7. Recent study showing the effect of caspase-8 catalytic activity during programmed cell death.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 363-7
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
-
61
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase rip as effector molecule
-
Holler N, Zaru R, Micheau O, et al. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol. 2000;1:489-95.
-
(2000)
Nat Immunol
, vol.1
, pp. 489-95
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
-
62
-
-
66449133280
-
Phosphorylation-driven assembly of the rip1-rip3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho YS, Challa S, Moquin D, et al. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell. 2009;137:1112-23.
-
(2009)
Cell
, vol.137
, pp. 1112-23
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
-
63
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to tnf-alpha
-
He S, Wang L, Miao L, et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell. 2009;137:1100-11.
-
(2009)
Cell
, vol.137
, pp. 1100-11
-
-
He, S.1
Wang, L.2
Miao, L.3
-
64
-
-
42249102086
-
Identification of rip1 kinase as a specific cellular target of necrostatins
-
Degterev A, Hitomi J, Germscheid M, et al. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol. 2008;4:313-21.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 313-21
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
-
66
-
-
84860584135
-
Inhibition of rip1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo
-
Recent in vivo study showing a positive effect of necrostatin during myocardial ischemia/reperfusion injury.
-
Oerlemans MIFJ, Liu J, Arslan F, et al. Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo. Basic Res Cardiol. 2012;107(4):270. Recent in vivo study showing a positive effect of necrostatin during myocardial ischemia/reperfusion injury.
-
(2012)
Basic Res Cardiol
, vol.107
, Issue.4
, pp. 270
-
-
Mifj, O.1
Liu, J.2
Arslan, F.3
-
67
-
-
79954525274
-
Necrostatin-1 ameliorates symptoms in r6/2 transgenic mouse model of huntington's disease
-
Zhu S, Zhang Y, Bai G, Li H. Necrostatin-1 ameliorates symptoms in R6/2 transgenic mouse model of Huntington's disease. Cell Death Dis. 2011;2:e115.
-
(2011)
Cell Death Dis
, vol.2
-
-
Zhu, S.1
Zhang, Y.2
Bai, G.3
Li, H.4
-
68
-
-
72649098216
-
Nitration of the mitochondrial complex i subunit ndufb8 elicits rip1-and rip3-mediated necrosis
-
Davis CW, Hawkins BJ, Ramasamy S, et al. Nitration of the mitochondrial complex I subunit NDUFB8 elicits RIP1-and RIP3-mediated necrosis. Free Radic Biol Med. 2010;48:306-17.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 306-17
-
-
Davis, C.W.1
Hawkins, B.J.2
Ramasamy, S.3
-
69
-
-
67650812332
-
Rip3, an energy metabolism regulator that switches tnf-induced cell death from apoptosis to necrosis
-
Zhang D-W, Shao J, Lin J, et al. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science (New York, NY). 2009;325(5938):332-6.
-
(2009)
Science (New York, NY)
, vol.325
, Issue.5938
, pp. 332-6
-
-
Zhang, D.-W.1
Shao, J.2
Lin, J.3
-
71
-
-
0028061670
-
Deregulated expression of e2f-1 induces s-phase entry and leads to apoptosis
-
Shan B, Lee WH. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol Cell Biol. 1994;14:8166-73.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 8166-73
-
-
Shan, B.1
Lee, W.H.2
-
72
-
-
0030296944
-
Human e2f-1 reactivates cell cycle progression in ventricular myocytes and represses cardiac gene transcription
-
Kirshenbaum LA, Abdellatif M, Chakraborty S, Schneider MD. Human E2F-1 reactivates cell cycle progression in ventricular myocytes and represses cardiac gene transcription. Dev Biol. 1996;179:402-11.
-
(1996)
Dev Biol
, vol.179
, pp. 402-11
-
-
Kirshenbaum, L.A.1
Abdellatif, M.2
Chakraborty, S.3
Schneider, M.D.4
-
73
-
-
58549107366
-
Antagonism of e2f-1 regulated bnip3 transcription by nf-kappab is essential for basal cell survival
-
Shaw J, Yurkova N, Zhang T, et al. Antagonism of E2F-1 regulated Bnip3 transcription by NF-kappaB is essential for basal cell survival. Proc Natl Acad Sci USA. 2008;105(52):20734-9.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.52
, pp. 20734-9
-
-
Shaw, J.1
Yurkova, N.2
Zhang, T.3
-
74
-
-
41949101511
-
The cell cycle factor e2f-1 activates bnip3 and the intrinsic death pathway in ventricular myocytes
-
Yurkova N, Shaw J, Blackie K, et al. The cell cycle factor E2F-1 activates Bnip3 and the intrinsic death pathway in ventricular myocytes. Circ Res. 2008;102(4):472-9.
-
(2008)
Circ Res
, vol.102
, Issue.4
, pp. 472-9
-
-
Yurkova, N.1
Shaw, J.2
Blackie, K.3
-
75
-
-
84867168974
-
Cognitive impairment and risk of cardiovascular events and mortality
-
First prospective study that shows a relationship between cognitive impairment and CV diseases
-
O'Donnell M, Teo K, Gao P, et al. Cognitive impairment and risk of cardiovascular events and mortality. Eur Heart J. 2012;33:1777-86. First prospective study that shows a relationship between cognitive impairment and CV diseases.
-
(2012)
Eur Heart J
, pp. 331777-331786
-
-
O'Donnell, M.1
Teo, K.2
Gao, P.3
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