Stercurensin inhibits nuclear factor-KB-dependent inflammatory signals through attenuation of TAK1-TAB1 complex formation

Journal of Cellular Biochemistry

Volumn 112, Issue 2, 2011, Pages 548-558

  Kim, Young Joo ^a   Kim, Han Cheon ^a   Ko, Hyeonseok ^a   Amor, Evangeline C ^b   Lee, Jong Wha ^b   Yang, Hyun Ok ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b University of the Philippines Diliman   (Philippines)

Author keywords

nitric oxide; nuclear factor KB; prostaglandin E2; stercurensin; tak1 binding protein 1; transforming growth factor activated kinase 1

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PROSTAGLANDIN E2; PROTEIN SERINE THREONINE KINASE; PROTEIN TAB1; STERCURENSIN; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; COMPLEX FORMATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; CHALCONE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; IMMUNOPRECIPITATION; LIPOPOLYSACCHARIDES; MALE; MAP KINASE KINASE KINASES; MICE; MICROSCOPY, CONFOCAL; NF-KAPPA B; NITRIC OXIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

MUS; SYZYGIUM SAMARANGENSE;

EID: 79251646629     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22945     Document Type: Article

References (40)

1. Ahmad S, Israf DA, Lajis NH, Shaari K, Mohamed H, Wahab AA, Ariffin KT, Hoo WY, Aziz NA, Kadir AA, Sulaiman MR, Somchit MN,. 2006. Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and whole blood. Eur J Pharmacol 538: 188-194.
2. Ajizian SJ, English BK, Meals EA,. 1999. Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon-gamma. J Infect Dis 179: 939-944.
3. Amor EC, Villaseñor IM, Ghayur MN, Gilani AH, Choudhary MI,. 2006. Presence of calcium antagonist activity explains the use of Syzygium samarangense in diarrhea. Phytother Res 20: 49-52.
4. Andreakos E, Sacre SM, Smith C, Lundberg A, Kiriakidis S, Stonehouse T, Monaco C, Feldmann M, Foxwell BM,. 2004. Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP. Immunobiology 103: 2229-2237.
5. Anjaneyulu ASR, Raju SN,. 1984. Stercurensin, a new C-methylchalcone from leaves of Sterculia urens. Indian J Chem 23B: 1010-1011.
6. Chen CW, Lee ST, Wu WT, Fu WM, Ho FM, Lin WW,. 2003. Signal transduction for inhibition of inducible nitric oxide synthase and cyclooxygenase-2 induction by capsaicin and related analogs in macrophages. Br J Pharmacol 140: 1077-1087.
7. Chen CH, Sheu MT, Chen TF, Wang YC, Hou WC, Liu DZ, Chung TC, Liang YC,. 2006. Suppression of endotoxin-induced proinflammatory responses by citrus pectin through blocking LPS signaling pathways. Biochem Pharmacol 72: 1001-1009.
8. Cho YH, Lee CH, Kim SG,. 2003. Potentiation of lipopolysaccharide- inducible cyclooxygenase 2 expression by C2-ceramide via c-Jun N-terminal kinase-mediated activation of CCAAT/enhancer binding protein beta in macrophages. Mol Pharmacol 63: 512-523.
9. Cho W, Park SJ, Shin JS, Noh YS, Cho EJ, Nam JH, Lee KT,. 2008. Anti-inflammatory effects of the methanol extract of Polytrichum commune via NF-kappaB inactivation in RAW264.7 macrophage cells. Biomol Ther 16: 385-393.
10. Hendrickse CW, Kelly RW, Radley S, Donovan IA, Keighley B, Neoptolemos JP,. 1994. Lipid peroxidation and prostaglandins in colorectal cancer. Br J Surg 81: 1219-1223.
11. Hinz B, Brune K,. 2002. Cyclooxygenase-2-10 years later. J Pharmacol Exp Ther 300: 367-375.
12. Hwang D, Fischer NH, Jang BC, Tak H, Kim JK, Lee W,. 1996. Inhibition of the expression of inducible cyclooxygenase and proinflammatory cytokines by sesquiterpene lactones in macrophages correlates with the inhibition of MAP kinases. Biochem Biophys Res Commun 226: 810-818.
13. Irie T, Muta T, Takeshige K,. 2000. TAK1 mediates an activation signal from toll-like receptor(s) to nuclear factor-kappaB in lipopolysaccharide- stimulated macrophages. FEBS Lett 467: 160-164.
14. Israf DA, Khaizurin TA, Syahida A, Lajis NH, Khozirah S,. 2007. Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-kappaB nuclear translocation and Ikappa-B phosphorylation in RAW 264.7 macrophage cells. Mol Immunol 44: 673-679.
15. Johnson GL, Lapadat R,. 2002. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298: 1911-1912.
16. Kim CS, Kawada T, Kim BS, Han IS, Choe SY, Kurata T, Yu R,. 2003. Capsaicin exhibits anti-inflammatory property by inhibiting IkB-a degradation in LPS-stimulated peritoneal macrophages. Cell Signal 15: 299-306.
17. Kim YJ, Ko H, Park JS, Han IH, Amor EC, Lee JW, Yang HO,. 2010. Dimethyl cardamonin inhibits lipopolysaccharide-induced inflammatory factors through blocking NF-kappaB p65 activation. Int Immunopharmacol 10: 1127-1134.
18. Koki AT, Leahy KM, Harmon JM, Masferrer JL,. 2003. Cyclooxygenase-2 and cancer. In:, Harris RE, editor. COX-2 blockade in cancer prevention and therapy. Totowa: Humana Press. pp 185-203.
19. Kuo YC, Yang LM, Lin LC,. 2004. Isolation and immunomodulatory effect of flavonoids from Syzygium samarangense. Planta Med 70: 1237-1239.
20. Lee JD, Mira-Arbibe L, Ulevitch RJ,. 2000. TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide. J Leukoc Biol 68: 909-915.
21. Liang YC, Huang YT, Tsai SH, Lin-Shiau SY, Chen CF, Lin JK,. 1999. Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages. Carcinogenesis 20: 1945-1952.
22. Lu YC, Yeh WC, Ohashi PS,. 2008. LPS/TLR4 signal transduction pathway. Cytokine 42: 145-151.
23. Moncada S, Palmer RM, Higgs EA,. 1991. Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 43: 109-142.
24. Muriel P,. 2000. Regulation of nitric oxide synthesis in the liver. J Appl Toxicol 20: 189-195.
25. Pasparakis M,. 2009. Regulation of tissue homeostasis by NF-kappaB signaling: Implications for inflammatory diseases. Nat Rev Immunol 9: 778-788.
26. Rajapakse N, Kim MM, Mendis E, Kim SK,. 2008. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 in lipopolysaccharide-stimulated RAW264.7 cells by carboxybutyrylated glucosamine takes place via down-regulation of mitogen-activated protein kinase-mediated nuclear factor-kappaB signaling. Immunology 123: 348-357.
27. Resurreccion-Magno MHC, Villasenor IM, Harada N, Monde K,. 2005. Antihyperglycaemic flavonoids from Syzygium samarangense (Blume) merr. and perry. Phytother Res 19: 246-253.
28. Sakurai H, Nishi A, Sato N, Mizukami J, Miyoshi H, Sugita T,. 2002. TAK1-TAB1 fusion protein: A novel constitutively active mitogen-activated protein kinase kinase kinase that stimulates AP-1 and NF-kappaB signaling pathways. Biochem Biophys Res Commun 297: 1277-1281.
29. Shan J, Fu J, Zhao Z, Kong X, Huang H, Luo L, Yin Z,. 2009. Chlorogenic acid inhibits lipopolysaccharide-induced cyclooxygenase-2 expression in RAW264.7 cells through suppressing NF-kappaB and JNK/AP-1 activation. Int Immunopharmacol 9: 1042-1048.
30. Shim JH, Xiao C, Paschal AE, Bailey ST, Rao P, Hayden MS, Lee KY, Bussey C, Steckel M, Tanaka N, Yamada G, Akira S, Matsumoto K, Ghosh S,. 2005. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathway in vivo. Genes Dev 19: 2668-2681.
31. Simirgiotis MJ, Adachi S, To S, Yang H, Reynertson KA, Basile MJ, Gil RR, Weinstein IB, Kennelly EJ,. 2008. Cytotoxic chalcones and antioxidants from the fruits of Syzygium samarangense (Wax Jambu). Food Chem 107: 813-819.
32. Smith WL, DeWitt DL, Garavito RM,. 2000. Cyclooxygenase: Structural, cellular, and molecular biology. Annu Rev Biochem 69: 145-182.
33. Surh YJ, Chun KS, Cha HH, Han SS, Keum YS, Park KK, Lee SS,. 2001. Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: Down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutat Res 480-481: 243-268.
34. Takaesu G, Surabhi RM, Park KJ, Ninomiya-Tsuji J, Matsumoto K, Gaynor RB,. 2003. TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway. J Mol Biol 326: 105-115.
35. Takeda K, Akira S,. 2004. TLR signaling pathways. Semin Immunol 16: 3-9.
36. Van den Berg AP, Twilhaar WN, van Son WJ, van der Bij W, Klompmaker IJ, Slooff MJ, The TH, de Leij LH,. 1998. Quantification of immunosuppression by flow cytometric measurement of intracellular cytokine synthesis. Transpl Int 11 (Suppl 1): S318-S321.
37. Wan F, Lenardo MJ,. 2010. The nuclear signaling of NF-kappaB: Current knowledge, new insights, and future perspectives. Cell Res 20: 24-33.
38. Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ,. 2001. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 412: 346-351.
39. Wang S, Liu Z, Wang L, Zhang X,. 2009. NF-kappaB signaling pathway, inflammation and colorectal cancer. Cell Mol Immunol 6: 327-334.
40. Yadav PN, Liu Z, Rafi MM,. 2003. A diarylheptanoid from lesser galangal (Alpinia officinarum) inhibits proinflammatory mediators via inhibition of mitogen-activated protein kinase, p44/42, and transcription factor nuclear factor-kappa B. J Pharmacol Exp Ther 305: 925-931.