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Volumn 108, Issue 11, 2012, Pages 3024-3033

Arcuate Src activation-induced phosphorylation of NR2B NMDA subunit contributes to inflammatory pain in rats

Author keywords

Arcuate nucleus; Inflammatory pain; NMDA receptor; NR2B subunit; Src tyrosine kinase

Indexed keywords

4 BENZYL ALPHA (4 HYDROXYPHENYL) BETA METHYL 1 PIPERIDINEPROPANOL; FREUND ADJUVANT; GLUTAMATE SODIUM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; PROTEIN KINASE P60;

EID: 84870502482     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.01047.2011     Document Type: Article
Times cited : (15)

References (59)
  • 1
    • 0035369919 scopus 로고    scopus 로고
    • NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity
    • Ali DW, Salter MW. NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity. Curr Opin Neurobiol 11: 336-342, 2001.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 336-342
    • Ali, D.W.1    Salter, M.W.2
  • 2
    • 0027979341 scopus 로고
    • Response of chronic neuropathic pain syndromes to ketamine: A preliminary study
    • Backonja M, Arndt G, Gombar KA, Check B, Zimmermann M. Response of chronic neuropathic pain syndromes to ketamine: a preliminary study. Pain 56: 51-57, 1994.
    • (1994) Pain , vol.56 , pp. 51-57
    • Backonja, M.1    Arndt, G.2    Gombar, K.A.3    Check, B.4    Zimmermann, M.5
  • 4
    • 0032987252 scopus 로고    scopus 로고
    • Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: Correlation with restricted localisation of NR2B subunit in dorsal horn
    • Boyce S, Wyatt A, Webb JK, O'Donnell R, Mason G, Rigby M, Siri nathsinghji D, Hill RG, Rupniak NM. Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn. Neuropharmacology 38: 611-623, 1999.
    • (1999) Neuropharmacology , vol.38 , pp. 611-623
    • Boyce, S.1    Wyatt, A.2    Webb, J.K.3    O'Donnell, R.4    Mason, G.5    Rigby, M.6    Siri, N.D.7    Hill, R.G.8    Rupniak, N.M.9
  • 5
    • 58249083141 scopus 로고    scopus 로고
    • The contributing role of CD14 in toll-like receptor 4 dependent neuropathic pain
    • Cao L, Tanga FY, Deleo JA. The contributing role of CD14 in toll-like receptor 4 dependent neuropathic pain. Neuroscience 158: 896-903, 2009.
    • (2009) Neuroscience , vol.158 , pp. 896-903
    • Cao, L.1    Tanga, F.Y.2    Deleo, J.A.3
  • 7
    • 0030933616 scopus 로고    scopus 로고
    • Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat
    • Chaplan SR, Malmberg AB, Yaksh TL. Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat. J Pharmacol Exp Ther 280: 829-838, 1997.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 829-838
    • Chaplan, S.R.1    Malmberg, A.B.2    Yaksh, T.L.3
  • 8
    • 0029890005 scopus 로고    scopus 로고
    • Protein tyrosine kinase-mediated potentiation of cur rents from cloned NMDA receptors
    • Chen C, Leonard JP. Protein tyrosine kinase-mediated potentiation of cur rents from cloned NMDA receptors. J Neurochem 67: 194-200, 1996.
    • (1996) J Neurochem , vol.67 , pp. 194-200
    • Chen, C.1    Leonard, J.P.2
  • 9
    • 58149503770 scopus 로고    scopus 로고
    • Administration of IL-1beta to the 4th ventricle causes anorexia that is blocked by agouti-related peptide and that coincides with activation of tyrosine-hydroxylase neurons in the nucleus of the solitary tract
    • DeBoer MD, Scarlett JM, Levasseur PR, Grant WF, Marks DL. Administration of IL-1beta to the 4th ventricle causes anorexia that is blocked by agouti-related peptide and that coincides with activation of tyrosine-hydroxylase neurons in the nucleus of the solitary tract. Peptides 30: 210-218, 2009.
    • (2009) Peptides , vol.30 , pp. 210-218
    • Deboer, M.D.1    Scarlett, J.M.2    Levasseur, P.R.3    Grant, W.F.4    Marks, D.L.5
  • 11
    • 0033974271 scopus 로고    scopus 로고
    • Alterations in subunit expression, composition, and phosphorylation of striatal N-methyl-D-aspartate glutamate receptors in a rat 6-hydroxydopamine model of Parkinson's disease
    • Dunah AW, Wang Y, Yasuda RP, Kameyama K, Huganir RL, Wolfe BB, Standaert DG. Alterations in subunit expression, composition, and phosphorylation of striatal N-methyl-D-aspartate glutamate receptors in a rat 6-hydroxydopamine model of Parkinson's disease. Mol Pharmacol 57: 342-352, 2000.
    • (2000) Mol Pharmacol , vol.57 , pp. 342-352
    • Dunah, A.W.1    Wang, Y.2    Yasuda, R.P.3    Kameyama, K.4    Huganir, R.L.5    Wolfe, B.B.6    Standaert, D.G.7
  • 12
    • 0035152963 scopus 로고    scopus 로고
    • Glutamate receptors and nociception: Implications for the drug treatment of pain
    • Fundytus ME. Glutamate receptors and nociception: implications for the drug treatment of pain. CNS Drugs 15: 29-58, 2001.
    • (2001) CNS Drugs , vol.15 , pp. 29-58
    • Fundytus, M.E.1
  • 13
    • 30844451008 scopus 로고    scopus 로고
    • Glutamate-based therapeutic approaches: NR2B receptor antago nists
    • Gogas KR. Glutamate-based therapeutic approaches: NR2B receptor antago nists. Curr Opin Pharmacol 6: 68-74, 2006.
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 68-74
    • Gogas, K.R.1
  • 14
    • 84870490941 scopus 로고
    • Effect of neonatal injection of monosodium glutamate on the analgesia produced by hypothalamic arcuate nucleus stimulation
    • Gong, S, Jiao YY, Yin WP, Yin QZ. Effect of neonatal injection of monosodium glutamate on the analgesia produced by hypothalamic arcuate nucleus stimulation. Chinese J Neurosci 1: 7-12, 1994.
    • (1994) Chinese J Neurosci , vol.1 , pp. 7-12
    • Gong, S.1    Jiao, Y.Y.2    Yin, W.P.3    Yin, Q.Z.4
  • 15
    • 49349114341 scopus 로고    scopus 로고
    • Localization of phospho tyrosine489-beta-adducin immunoreactivity in the hypothalamic tanycytes and its involvement in energy homeostasis
    • Gotoh H, Okumura A, Nagai K, Okumura N. Localization of phospho tyrosine489-beta-adducin immunoreactivity in the hypothalamic tanycytes and its involvement in energy homeostasis. Brain Res 1228: 97-106, 2008.
    • (2008) Brain Res , vol.1228 , pp. 97-106
    • Gotoh, H.1    Okumura, A.2    Nagai, K.3    Okumura, N.4
  • 16
    • 0030671405 scopus 로고    scopus 로고
    • Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses
    • Gu JG, MacDermott AB. Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses. Nature 389: 749-753, 1997.
    • (1997) Nature , vol.389 , pp. 749-753
    • Gu, J.G.1    Macdermott, A.B.2
  • 17
    • 0020635789 scopus 로고
    • Effects of neonatal administration of monosodium glutamate on morphine-, acupuncture- and stress-analgesia in adult rats
    • Guo SY, Yin WP, Yin QZ. Effects of neonatal administration of monosodium glutamate on morphine-, acupuncture- and stress-analgesia in adult rats. Zhongguo Yao Li Xue Bao 4: 14-16, 1983.
    • (1983) Zhongguo Yao Li Xue Bao , vol.4 , pp. 14-16
    • Guo, S.Y.1    Yin, W.P.2    Yin, Q.Z.3
  • 18
    • 5644256896 scopus 로고    scopus 로고
    • Group I metabotropic glutamate receptor NMDA receptor coupling and signaling cascade mediate spinal dorsal horn NMDA receptor 2B tyrosine phosphorylation associated with inflammatory hyperalgesia
    • Guo W, Wei F, Zou S, Robbins MT, Sugiyo S, Ikeda T, Tu JC, Worley PF, Dubner R, Ren K. Group I metabotropic glutamate receptor NMDA receptor coupling and signaling cascade mediate spinal dorsal horn NMDA receptor 2B tyrosine phosphorylation associated with inflammatory hyperalgesia. J Neurosci 24: 9161-9173, 2004.
    • (2004) J Neurosci , vol.24 , pp. 9161-9173
    • Guo, W.1    Wei, F.2    Zou, S.3    Robbins, M.T.4    Sugiyo, S.5    Ikeda, T.6    Tu, J.C.7    Worley, P.F.8    Dubner, R.9    Ren, K.10
  • 19
    • 0037101627 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia
    • Guo W, Zou S, Guan Y, Ikeda T, Tal M, Dubner R, Ren K. Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia. J Neurosci 22: 6208-6217, 2002.
    • (2002) J Neurosci , vol.22 , pp. 6208-6217
    • Guo, W.1    Zou, S.2    Guan, Y.3    Ikeda, T.4    Tal, M.5    Dubner, R.6    Ren, K.7
  • 20
    • 0023193951 scopus 로고
    • Differential sensitivity of models of antinociception in the rat, mouse and guinea-pig to mu- and kappa-opioid receptor agonists
    • Hayes AG, Sheehan MJ, Tyers MB. Differential sensitivity of models of antinociception in the rat, mouse and guinea-pig to mu- and kappa-opioid receptor agonists. Br J Pharmacol 91: 823-832, 1987.
    • (1987) Br J Pharmacol , vol.91 , pp. 823-832
    • Hayes, A.G.1    Sheehan, M.J.2    Tyers, M.B.3
  • 21
    • 65649099391 scopus 로고    scopus 로고
    • NR2B receptor blockade inhibits pain related sensitization of amygdala neurons
    • Ji G, Horvath C, Neugebauer V. NR2B receptor blockade inhibits pain related sensitization of amygdala neurons. Mol Pain 5: 21, 2009.
    • (2009) Mol Pain , vol.5 , pp. 21
    • Ji, G.1    Horvath, C.2    Neugebauer, V.3
  • 22
    • 0037316640 scopus 로고    scopus 로고
    • Cold allodynia and hyperalgesia in neuropathic pain: The effect of N-methyl-D-aspartate (NMDA) receptor antagonist ketamine-a double-blind, cross-over comparison with alfentanil and placebo
    • Jorum E, Warncke T, Stubhaug A. Cold allodynia and hyperalgesia in neuropathic pain: the effect of N-methyl-D-aspartate (NMDA) receptor antagonist ketamine-a double-blind, cross-over comparison with alfentanil and placebo. Pain 101: 229-235, 2003.
    • (2003) Pain , vol.101 , pp. 229-235
    • Jorum, E.1    Warncke, T.2    Stubhaug, A.3
  • 23
    • 14044269308 scopus 로고    scopus 로고
    • Widespread pain in fibromyalgia is related to a deficit of endogenous pain inhibition
    • Julien N, Goffaux P, Arsenault P, Marchand S. Widespread pain in fibromyalgia is related to a deficit of endogenous pain inhibition. Pain 114: 295-302, 2005.
    • (2005) Pain , vol.114 , pp. 295-302
    • Julien, N.1    Goffaux, P.2    Arsenault, P.3    Marchand, S.4
  • 24
    • 0029093990 scopus 로고
    • Differential tyrosine phosphorylation of N-methyl-D- aspartate receptor subunits
    • Lau LF, Huganir RL. Differential tyrosine phosphorylation of N-methyl-D- aspartate receptor subunits. J Biol Chem 270: 20036-20041, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 20036-20041
    • Lau, L.F.1    Huganir, R.L.2
  • 25
    • 69449083564 scopus 로고    scopus 로고
    • Acute brown adipose tissue temperature response to cold in monosodium glutamate-treated Siberian hamsters
    • Leitner C, Bartness TJ. Acute brown adipose tissue temperature response to cold in monosodium glutamate-treated Siberian hamsters. Brain Res 1292: 38-51, 2009.
    • (2009) Brain Res , vol.1292 , pp. 38-51
    • Leitner, C.1    Bartness, T.J.2
  • 26
    • 3242722313 scopus 로고    scopus 로고
    • Block of NMDA and non-NMDA receptor activation results in reduced background and evoked activity of central amygdale neurons in a model of arthritic pain
    • Li W, Neugebauer V. Block of NMDA and non-NMDA receptor activation results in reduced background and evoked activity of central amygdale neurons in a model of arthritic pain. Pain 110: 112-122, 2004.
    • (2004) Pain , vol.110 , pp. 112-122
    • Li, W.1    Neugebauer, V.2
  • 27
    • 0034659716 scopus 로고    scopus 로고
    • CA1 pyramidal neurons of the hippocampus protein kinase C regulates calcium-dependent inactivation of NMDA receptors
    • Lu WY, Jackson MF, Bai D, Orser BA, MacDonald JF. In CA1 pyramidal neurons of the hippocampus protein kinase C regulates calcium-dependent inactivation of NMDA receptors. J Neurosci 20: 4452-4461, 2000.
    • (2000) J Neurosci , vol.20 , pp. 4452-4461
    • Lu, W.Y.1    Jackson, M.F.2    Bai, D.3    Orser, B.A.4    Macdonald, J.F.5
  • 28
    • 33847105586 scopus 로고    scopus 로고
    • Electrical inhibition of identified anorexigenic POMC neurons by orexin/hypocretin
    • Ma X, Zubcevic L, Bruning JC, Ashcroft FM, Burdakov D. Electrical inhibition of identified anorexigenic POMC neurons by orexin/hypocretin. J Neurosci 27: 1529-1533, 2007.
    • (2007) J Neurosci , vol.27 , pp. 1529-1533
    • Ma, X.1    Zubcevic, L.2    Bruning, J.C.3    Ashcroft, F.M.4    Burdakov, D.5
  • 29
    • 4544233776 scopus 로고    scopus 로고
    • Setting the tone: Superficial dorsal horn projection neurons regulate pain sensitivity
    • Mantyh PW, Hunt SP. Setting the tone: superficial dorsal horn projection neurons regulate pain sensitivity. Trends Neurosci 27: 582-584, 2004.
    • (2004) Trends Neurosci , vol.27 , pp. 582-584
    • Mantyh, P.W.1    Hunt, S.P.2
  • 30
    • 0027466924 scopus 로고
    • Intrathecal treatment with dextrorphan or ketamine potently reduces pain-related behaviors in a rat model of peripheral mononeuropathy
    • Mao J, Price DD, Hayes RL, Lu J, Mayer DJ, Frenk H. Intrathecal treatment with dextrorphan or ketamine potently reduces pain-related behaviors in a rat model of peripheral mononeuropathy. Brain Res 605: 164-168, 1993.
    • (1993) Brain Res , vol.605 , pp. 164-168
    • Mao, J.1    Price, D.D.2    Hayes, R.L.3    Lu, J.4    Mayer, D.J.5    Frenk, H.6
  • 31
    • 0027967347 scopus 로고
    • Dextromethorphan for the treatment of neuropathic pain: A double-blind randomised controlled crossover trial with integral n-of-1 design
    • McQuay HJ, Carroll D, Jadad AR, Glynn CJ, Jack T, Moore RA, Wiffeh PJ. Dextromethorphan for the treatment of neuropathic pain: a double-blind randomised controlled crossover trial with integral n-of-1 design. Pain 59: 127-133, 1994.
    • (1994) Pain , vol.59 , pp. 127-133
    • McQuay, H.J.1    Carroll, D.2    Jadad, A.R.3    Glynn, C.J.4    Jack, T.5    Moore, R.A.6    Wiffeh, P.J.7
  • 32
    • 0029556408 scopus 로고
    • Tyrosine phos phorylation of NMDA receptor in rat striatum: Effects of 6-OH-dopamine lesions
    • Menegoz M, Lau LF, Herve D, Huganir RL, Girault JA. Tyrosine phos phorylation of NMDA receptor in rat striatum: effects of 6-OH-dopamine lesions. Neuroreport 7: 125-128, 1995.
    • (1995) Neuroreport , vol.7 , pp. 125-128
    • Menegoz, M.1    Lau, L.F.2    Herve, D.3    Huganir, R.L.4    Girault, J.A.5
  • 33
    • 0028343648 scopus 로고
    • Develop mental and regional expression in the rat brain and functional properties of four NMDA receptors
    • Monyer H, Burnashev N, Laurie DJ, Sakmann B, Seeburg PH. Develop mental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12: 529-540, 1994.
    • (1994) Neuron , vol.12 , pp. 529-540
    • Monyer, H.1    Burnashev, N.2    Laurie, D.J.3    Sakmann, B.4    Seeburg, P.H.5
  • 34
    • 0000927212 scopus 로고
    • The major tyrosine-phosphorylated protein in the postsynaptic density fraction is N-methyl-D-aspartate receptor subunit 2B
    • Moon IS, Apperson ML, Kennedy MB. The major tyrosine-phosphorylated protein in the postsynaptic density fraction is N-methyl-D-aspartate receptor subunit 2B. Proc Natl Acad Sci USA 91: 3954-3958, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3954-3958
    • Moon, I.S.1    Apperson, M.L.2    Kennedy, M.B.3
  • 35
    • 79551662523 scopus 로고    scopus 로고
    • Enhanced NMDA receptor NR1 phosphorylation and neuronal activity in the arcuate nucleus of hypothalamus following peripheral inflammation
    • Peng J, Xu L, Zhu Q, Gong S, Yu X, Guo S, Wu G, Tao J, Jiang X. Enhanced NMDA receptor NR1 phosphorylation and neuronal activity in the arcuate nucleus of hypothalamus following peripheral inflammation. Acta Pharmacol Sin 32: 160-167, 2011.
    • (2011) Acta Pharmacol Sin , vol.32 , pp. 160-167
    • Peng, J.1    Xu, L.2    Zhu, Q.3    Gong, S.4    Yu, X.5    Guo, S.6    Wu, G.7    Tao, J.8    Jiang, X.9
  • 36
    • 0141458065 scopus 로고    scopus 로고
    • The role of N-methyl-D aspartate (NMDA) receptors in pain: A review
    • Petrenko AB, Yamakura T, Baba H, Shimoji K. The role of N-methyl-D aspartate (NMDA) receptors in pain: a review. Anesth Analg 97: 1108-1116, 2003.
    • (2003) Anesth Analg , vol.97 , pp. 1108-1116
    • Petrenko, A.B.1    Yamakura, T.2    Baba, H.3    Shimoji, K.4
  • 39
    • 0027501057 scopus 로고
    • NMDA receptor antagonists attenuate mechanical hyper-algesia in rats with unilateral inflammation of the hindpaw
    • Ren K, Dubner R. NMDA receptor antagonists attenuate mechanical hyper-algesia in rats with unilateral inflammation of the hindpaw. Neurosci Lett 163: 22-26, 1993.
    • (1993) Neurosci Lett , vol.163 , pp. 22-26
    • Ren, K.1    Dubner, R.2
  • 40
    • 0029789826 scopus 로고    scopus 로고
    • Long-term potentiation increases tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit 2B in rat dentate gyrus in vivo
    • Rosenblum K, Dudai Y, Richter-Levin G. Long-term potentiation increases tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit 2B in rat dentate gyrus in vivo. Proc Natl Acad Sci USA 93: 10457-10460, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10457-10460
    • Rosenblum, K.1    Dudai, Y.2    Richter-Levin, G.3
  • 41
    • 0029833009 scopus 로고    scopus 로고
    • Enhanced tyrosine phosphorylation of the 2B subunit of the N-methyl-D-aspartate receptor in long-term potentiation
    • Rostas JA, Brent VA, Voss K, Errington ML, Bliss TV, Gurd JW. Enhanced tyrosine phosphorylation of the 2B subunit of the N-methyl-D-aspartate receptor in long-term potentiation. Proc Natl Acad Sci USA 93: 10452-10456, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10452-10456
    • Rostas, J.A.1    Brent, V.A.2    Voss, K.3    Errington, M.L.4    Bliss, T.V.5    Gurd, J.W.6
  • 42
    • 0038582461 scopus 로고    scopus 로고
    • Induction of galanin-like peptide gene expression in the rat posterior pituitary gland during endotoxin shock and adjuvant arthritis
    • Saito J, Ozaki Y, Ohnishi H, Nakamura T, Ueta Y. Induction of galanin-like peptide gene expression in the rat posterior pituitary gland during endotoxin shock and adjuvant arthritis. Brain Res Mol Brain Res 113: 124-132, 2003.
    • (2003) Brain Res Mol Brain Res , vol.113 , pp. 124-132
    • Saito, J.1    Ozaki, Y.2    Ohnishi, H.3    Nakamura, T.4    Ueta, Y.5
  • 43
    • 1842731881 scopus 로고    scopus 로고
    • Src kinases: A hub for NMDA receptor regulation
    • Salter MW, Kalia LV. Src kinases: a hub for NMDA receptor regulation. Nat Rev Neurosci 5: 317-328, 2004.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 317-328
    • Salter, M.W.1    Kalia, L.V.2
  • 44
    • 0036776058 scopus 로고    scopus 로고
    • Consequences of monosodium glutamate or goldthioglucose arcuate nucleus lesions on ethanol-induced locomotion
    • Sanchis-Segura C, Aragon CM. Consequences of monosodium glutamate or goldthioglucose arcuate nucleus lesions on ethanol-induced locomotion. Drug Alcohol Depend 68: 189-194, 2002.
    • (2002) Drug Alcohol Depend , vol.68 , pp. 189-194
    • Sanchis-Segura, C.1    Aragon, C.M.2
  • 45
    • 0035968929 scopus 로고    scopus 로고
    • Knockdown of PSD-95/SAP90 delays the development of neuropathic pain in rats
    • Tao F, Tao YX, Gonzalez JA, Fang M, Mao P, Johns RA. Knockdown of PSD-95/SAP90 delays the development of neuropathic pain in rats. Neuroreport 12: 3251-3255, 2001.
    • (2001) Neuroreport , vol.12 , pp. 3251-3255
    • Tao, F.1    Tao, Y.X.2    Gonzalez, J.A.3    Fang, M.4    Mao, P.5    Johns, R.A.6
  • 46
    • 0031040615 scopus 로고    scopus 로고
    • Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies
    • Tingley WG, Ehlers MD, Kameyama K, Doherty C, Ptak JB, Riley CT, Huganir RL. Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies. J Biol Chem 272: 5157-5166, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 5157-5166
    • Tingley, W.G.1    Ehlers, M.D.2    Kameyama, K.3    Doherty, C.4    Ptak, J.B.5    Riley, C.T.6    Huganir, R.L.7
  • 47
    • 79952664125 scopus 로고    scopus 로고
    • Acute inflammation increases pituitary and hypothalamic glycoprotein hormone subunit B5 mRNA expression in association with decreased thyrotrophin receptor mRNA expression in mice
    • van Zeijl CJ, Surovtseva OV, Wiersinga WM, Fliers E, Boelen A. Acute inflammation increases pituitary and hypothalamic glycoprotein hormone subunit B5 mRNA expression in association with decreased thyrotrophin receptor mRNA expression in mice. J Neuroendocrinol 23: 310-319, 2011.
    • (2011) J Neuroendocrinol , vol.23 , pp. 310-319
    • van Zeijl, C.J.1    Surovtseva, O.V.2    Wiersinga, W.M.3    Fliers, E.4    Boelen, A.5
  • 48
    • 0025323120 scopus 로고
    • Analgesic electrical stimulation of the hypothalamic arcuate nucleus: Tolerance and its cross-tolerance to 2 Hz or 100 Hz electroacupuncture
    • Wang Q, Mao L, Han J. Analgesic electrical stimulation of the hypothalamic arcuate nucleus: tolerance and its cross-tolerance to 2 Hz or 100 Hz electroacupuncture. Brain Res 518: 40-46, 1990a.
    • (1990) Brain Res , vol.518 , pp. 40-46
    • Wang, Q.1    Mao, L.2    Han, J.3
  • 49
    • 0025329735 scopus 로고
    • Characterization of inhibition of spinal nocice ptive reflex by stimulation of the arcuate nucleus of the hypothalamus in the pentobarbital-anesthetized rat
    • Wang Q, Mao LM, Han JS. Characterization of inhibition of spinal nocice ptive reflex by stimulation of the arcuate nucleus of the hypothalamus in the pentobarbital-anesthetized rat. Pain 41: 101-108, 1990b.
    • (1990) Pain , vol.41 , pp. 101-108
    • Wang, Q.1    Mao, L.M.2    Han, J.S.3
  • 51
    • 0034625770 scopus 로고    scopus 로고
    • Neuronal plasticity: Increasing the gain in pain
    • Woolf CJ, Salter MW. Neuronal plasticity: increasing the gain in pain. Science 288: 1765-1769, 2000.
    • (2000) Science , vol.288 , pp. 1765-1769
    • Woolf, C.J.1    Salter, M.W.2
  • 53
    • 0033223820 scopus 로고    scopus 로고
    • Src potentiation of NMDA receptors in hippocampal and spinal neurons is not mediated by reducing zinc inhibition
    • Xiong ZG, Pelkey KA, Lu WY, Lu YM, Roder JC, MacDonald JF, Salter MW. Src potentiation of NMDA receptors in hippocampal and spinal neurons is not mediated by reducing zinc inhibition. J Neurosci 19: RC37, 1999.
    • (1999) J Neurosci , vol.19
    • Xiong, Z.G.1    Pelkey, K.A.2    Lu, W.Y.3    Lu, Y.M.4    Roder, J.C.5    Macdonald, J.F.6    Salter, M.W.7
  • 54
    • 58149391339 scopus 로고    scopus 로고
    • Activation of the neuronal extracellular signal-regulated kinase 2 in the spinal cord dorsal horn is required for complete Freund's adjuvant-induced pain hypersensitivity
    • Xu Q, Garraway SM, Weyerbacher AR, Shin SJ, Inturrisi CE. Activation of the neuronal extracellular signal-regulated kinase 2 in the spinal cord dorsal horn is required for complete Freund's adjuvant-induced pain hypersensitivity. J Neurosci 28: 14087-14096, 2008.
    • (2008) J Neurosci , vol.28 , pp. 14087-14096
    • Xu, Q.1    Garraway, S.M.2    Weyerbacher, A.R.3    Shin, S.J.4    Inturrisi, C.E.5
  • 55
    • 0021322159 scopus 로고
    • Changes in unit discharge of hypothalamic arcuate nucleus area during noxious stimulation or acupuncture in rats
    • Yu XM, Yin QZ. Changes in unit discharge of hypothalamic arcuate nucleus area during noxious stimulation or acupuncture in rats. J Acta Physiol Sinica 1: 33-41, 1984.
    • (1984) J Acta Physiol Sinica , vol.1 , pp. 33-41
    • Yu, X.M.1    Yin, Q.Z.2
  • 56
    • 0031053363 scopus 로고    scopus 로고
    • NMDA channel regulation by channel-associated protein tyrosine kinase Src
    • Yu XM, Askalan R, Keil GJ II, Salter MW. NMDA channel regulation by channel-associated protein tyrosine kinase Src. Science 275: 674-678, 1997.
    • (1997) Science , vol.275 , pp. 674-678
    • Yu, X.M.1    Askalan, R.2    Keil, G.J.I.I.3    Salter, M.W.4
  • 57
    • 0024216723 scopus 로고
    • Involvement of rat locus coeruleus in the analgesic effect induced by monosodium glutamate injection into the hypothalamic arcuate nucleus area
    • Zhang N, Yin QZ. Involvement of rat locus coeruleus in the analgesic effect induced by monosodium glutamate injection into the hypothalamic arcuate nucleus area. Sheng Li Xue Bao 40: 529-538, 1988.
    • (1988) Sheng Li Xue Bao , vol.40 , pp. 529-538
    • Zhang, N.1    Yin, Q.Z.2
  • 58
    • 0023316950 scopus 로고
    • Effects of lesion and stimulation of hypothalamic arcuate nucleus region on leu-enkephalin, dopamine and norepinephrine contents in rat brain and spinal cord
    • Zhu MY, Gu XD, Zhang JW, Zhang DX. Effects of lesion and stimulation of hypothalamic arcuate nucleus region on leu-enkephalin, dopamine and norepinephrine contents in rat brain and spinal cord. Sheng Li Xue Bao 39: 197-201, 1987.
    • (1987) Sheng Li Xue Bao , vol.39 , pp. 197-201
    • Zhu, M.Y.1    Gu, X.D.2    Zhang, J.W.3    Zhang, D.X.4
  • 59
    • 0034666110 scopus 로고    scopus 로고
    • Enhanced phosphorylation of NMDA receptor 1 subunits in spinal cord dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rats
    • Zou X, Lin Q, Willis WD. Enhanced phosphorylation of NMDA receptor 1 subunits in spinal cord dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rats. J Neurosci 20: 6989-6997, 2000.
    • (2000) J Neurosci , vol.20 , pp. 6989-6997
    • Zou, X.1    Lin, Q.2    Willis, W.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.