IL-1β stimulation of CCD-18co myofibroblasts enhances repair of epithelial monolayers through Wnt-5a

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 303, Issue 11, 2012, Pages

  Raymond, Meera ^a   Marchbank, Tania ^a,b   Moyer, Mary P ^c   Playford, Raymond J ^a,b   Sanderson, Ian R ^a   Kruidenier, Laurens ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF PLYMOUTH   (United Kingdom)

^c INCELL ^*  (United States)

Author keywords

catenin; Noncanonical; Wound healing

Indexed keywords

BETA CATENIN; DICKKOPF 1 PROTEIN; INTERLEUKIN 1BETA; MYC PROTEIN; RECOMBINANT PROTEIN; SUCRASE ISOMALTASE; WNT5A PROTEIN;

AGED; ARTICLE; CELL DEDIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN CACO 2; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; EPITHELIUM; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INTESTINE EPITHELIUM; INTESTINE EPITHELIUM CELL; MALE; MESENCHYME CELL; MICROARRAY ANALYSIS; MONOLAYER CULTURE; MYOFIBROBLAST; NORMAL HUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION; WOUND CLOSURE; WOUND HEALING;

BETA CATENIN; CACO-2 CELLS; CELL DEDIFFERENTIATION; CELL LINE; CELL MOVEMENT; CULTURE MEDIA, CONDITIONED; DOWN-REGULATION; HUMANS; INTERLEUKIN-1BETA; MYOFIBROBLASTS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; UP-REGULATION; WNT PROTEINS; WOUND HEALING;

EID: 84870500608     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00458.2011     Document Type: Article

References (38)

1. Alex P, Zachos NC, Nguyen T, Gonzales L, Chen TE, Conklin LS, Centola M, Li X. Distinct cytokine patterns identified from multiplex profiles of murine DSS, and TNBS-induced colitis. Inflamm Bowel Dis 15: 341-352, 2009.
2. Andoh A, Bamba S, Brittan M, Fujiyama Y, Wright NA. Role of intestinal subepithelial myofibroblasts in inflammation and regenerative response in the gut. Pharmacol Ther 114: 94-106, 2007.
3. Bienz M, Clevers H. Linking colorectal cancer to Wnt signaling. Cell 103: 311-320, 2000.
4. Carmona-Fontaine C, Matthews HK, Kuriyama S, Moreno M, Dunn GA, Parsons M, Stern CD, Mayor R. Contact inhibition of locomotion in vivo controls neural crest directional migration. Nature 456: 957-961, 2008.
5. Dieleman LA, Palmen MJ, Akol H, Bloemena E, Peña AS, Meuwissen SG, Van Rees EP. Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines. Clin Exp Immunol 114: 385-391, 1998.
6. Egger B, Bajaj-Elliott M, MacDonald TT, Inglin R, Eysselein VE, Büchler MW. Characterisation of acute murine dextran sodium sulphate colitis: cytokine profile and dose dependency. Digestion 62: 240-248, 2000.
7. Gregorieff A, Pinto D, Begthel H, Destrée O, Kielman M, Clevers H. Expression pattern of Wnt signaling components in the adult intestine. Gastroenterology 129: 626-638, 2005.
8. Han DS, Li F, Holt L, Connolly K, Hubert M, Miceli R, Okoye Z, Santiago G, Windle K, Wong E, Sartor RB. Keratinocyte growth factor-2 (FGF-10) promotes healing of experimental small intestinal ulceration in rats. Am J Physiol Gastrointest Liver Physiol 279: G1011-G1022, 2000.
9. Hinterleitner TA, Saada JI, Berschneider HM, Powell DW, Valentich JD. IL-1 stimulates intestinal myofibroblast COX gene expression and augments activation of Cl-secretion in T84 cells. Am J Physiol Cell Physiol 271: C1262-C1268, 1996.
10. Hughes KR, Sablitzky F, Mahida YR. Expression profiling of Wnt family of genes in normal and inflammatory bowel disease primary human intestinal myofibroblasts and normal human colonic crypt epithelial cells. Inflamm Bowel Dis 17: 213-220, 2011.
11. Khalil AA, Friedl P. Determinants of leader cells in collective cell migration. Integr Biol (Camb) 2: 568-574, 2010.
12. Koch S, Nava P, Addis C, Kim W, Denning TL, Li L, Parkos CA, Nusrat A. The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair. Gastroenterology 141: 259-268, 2011.
13. -/- mice and Peutz-Jeghers syndrome. J Pathol 223: 584-592, 2011.
14. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T) Method. Methods 25: 402-408, 2001.
15. Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 20: 781-810, 2004.
16. MacDonald TT, Monteleone G. Immunity, inflammation, and allergy in the gut. Science 307: 1920-1925, 2005.
17. Maldonado-Contreras AL, McCormick BA. Intestinal epithelial cells and their role in innate mucosal immunity. Cell Tissue Res 343: 5-12, 2011.
18. Marchbank T, Mahmood A, Harten S, Maxwell PH, Playford RJ. Dimethyloxalyglycine stimulates the early stages of gastrointestinal repair processes through VEGF-dependent mechanisms. Lab Invest 91: 1684-1694, 2011.
19. Marchiando AM, Graham WV, Turner JR. Epithelial barriers in homeostasis and disease. Annu Rev Pathol 5: 119-144, 2010.
20. Masiakowski P, Carroll RD. A novel family of cell surface receptors with tyrosine kinase-like domain. J Biol Chem 267: 26181-26190, 1992.
21. McDonald SL, Silver A. The opposing roles of Wnt-5a in cancer. Br J Cancer 101: 209-214, 2009.
22. McKaig BC, Makh SS, Hawkey CJ, Podolsky DK, Mahida YR. Normal human colonic subepithelial myofibroblasts enhance epithelial migration (restitution) via TGF-β3. Am J Physiol Gastrointest Liver Physiol 276: G1087-G1093, 1999.
23. Minami Y, Oishi I, Endo M, Nishita M. Ror-family receptor tyrosine kinases in noncanonical Wnt signaling: their implications in developmental morphogenesis and human diseases. Dev Dyn 239: 1-15, 2010.
24. Moyer MP, Manzano LA, Merriman RL, Stauffer JS, Tanzer LR. NCM460, a normal human colon mucosal epithelial cell line. In Vitro Cell Devel Biol Anim 32: 315-317, 1996.
25. Nishita M, Yoo SK, Nomachi A, Kani S, Sougawa N, Ohta Y, Takada S, Kikuchi A, Minami Y. Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration. J Cell Biol 175: 555-562, 2006.
26. Nomachi A, Nishita M, Inaba D, Enomoto M, Hamasaki M, Minami Y. Receptor tyrosine kinase Ror2 mediates Wnt5a-induced polarized cell migration by activating c-Jun N-terminal kinase via actin-binding protein filamin A. J Biol Chem 283: 27973-27981, 2008.
27. Oishi I, Suzuki H, Onishi N, Takada R, Kani S, Ohkawara B, Koshida I, Suzuki K, Yamada G, Schwabe GC, Mundlos S, Shibuya H, Takada S, Minami Y. The receptor tyrosine kinase Ror2 is involved in noncanonical Wnt5a/JNK signaling pathway. Genes Cells 8: 645-654, 2003.
28. Pacheco II, Macleod RJ. CaSR stimulates secretion of Wnt5a from colonic myofibroblasts to stimulate CDX2 and sucrase-isomaltase using Ror2 on intestinal epithelia. Am J Physiol Gastrointest Liver Physiol 295: G748-G759, 2008.
29. Powell DW, Adegboyega PA, Di Mari JF, Mifflin RC. Epithelial cells and their neighbors I. Role of intestinal myofibroblasts in development, repair, and cancer. Am J Physiol Gastrointest Liver Physiol 289: G2-G7, 2005.
30. Radtke F, Clevers H. Self-renewal and cancer of the gut: two sides of a coin. Science 307: 1904-1909, 2005.
31. Rao TP, Kühl M. An updated overview on Wnt signaling pathways: a prelude for more. Circ Res 106: 1798-1806, 2010.
32. Semenov MV, Habas R, Macdonald BT, He X. SnapShot: Noncanonical Wnt Signaling Pathways. Cell 131: 1378, 2007.
33. Serhan CN, Savill J. Resolution of inflammation: the beginning programs the end. Nat Immunol 6: 1191-1197, 2005.
34. Shao J, Sheng GG, Mifflin RC, Powell DW, Sheng H. Roles of myofibroblasts in prostaglandin E2-stimulated intestinal epithelial proliferation and angiogenesis. Cancer Res 66: 846-855, 2006.
35. Takahashi M, Ota S, Shimada T, Hamada E, Kawabe T, Okudaira T, Matsumura M, Kaneko N, Terano A, Nakamura T, et al. Hepatocyte growth factor is the most potent endogenous stimulant of rabbit gastric epithelial cell proliferation and migration in primary culture. J Clin Invest 95: 1994-2003, 1995.
36. Weng M, Walker WA, Sanderson IR. Butyrate regulates the expression of pathogen-triggered IL-8 in intestinal epithelia. Pediatr Res 62: 542-546, 2007.
37. Yamaguchi TP, Bradley A, McMahon AP, Jones S. A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development 126: 1211-1223, 1999.
38. Znalesniak EB, Dürer U, Hoffmann W. Expression profiling of stationary and migratory intestinal epithelial cells after in vitro wounding: restitution is accompanied by cell differentiation. Cell Physiol Biochem 24: 125-132, 2009.