Comparison of hematologic, biochemical, and coagulation parameters in α1,3-galactosyltransferase gene-knockout pigs, wild-type pigs, and four primate species

Xenotransplantation

Volumn 19, Issue 6, 2012, Pages 342-354

  Ekser, Burcin ^a,b   Bianchi, John ^c   Ball, Suyapa ^c   Iwase, Hayato ^a   Walters, Anneke ^c   Ezzelarab, Mohamed ^a   Veroux, Massimiliano ^b   Gridelli, Bruno ^a,d   Wagner, Robert ^e   Ayares, David ^c   Cooper, David K C ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF CATANIA   (Italy)

^c REVIVICOR INC   (United States)

^d MEDITERRANEAN INSTITUTE FOR TRANSPLANTATION AND ADVANCED SPECIALIZED THERAPIES ISMETT   (Italy)

^e UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

1,3 galactosyltransferase gene knockout; coagulation; genetically engineered; hematology; pig; plasma biochemistry; swine

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ALPHA 1,3 GALACTOSYLTRANSFERASE; AMINOTRANSFERASE; AMYLASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CALCIUM; CARBON DIOXIDE; CHLORIDE; CHOLESTEROL; CREATINE KINASE; CREATINE KINASE MB; CREATININE; D DIMER; DECAY ACCELERATING FACTOR; FIBRINOGEN; FIBRINOGEN DEGRADATION PRODUCT; GLUCOSE; HEMOGLOBIN; IRON; LACTATE DEHYDROGENASE; MEMBRANE COFACTOR PROTEIN; PHOSPHORUS; POTASSIUM; SODIUM; THROMBOMODULIN; TROPONIN I; UREA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; AMYLASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BABOON; BILIRUBIN BLOOD LEVEL; BLOOD CLOTTING; CALCIUM BLOOD LEVEL; CARBON DIOXIDE BLOOD LEVEL; CHLORIDE BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CREATININE BLOOD LEVEL; DNA MODIFICATION; ERYTHROCYTE COUNT; FEMALE; FIBRINOGEN BLOOD LEVEL; GENE INACTIVATION; GLUCOSE BLOOD LEVEL; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HUMAN; INTERNATIONAL NORMALIZED RATIO; IRON BLOOD LEVEL; KIDNEY FUNCTION; LACTATE DEHYDROGENASE BLOOD LEVEL; LEUKOCYTE COUNT; LIVER FUNCTION; MACACA FASCICULARIS; MALE; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; MEDICAL RESEARCH; NONHUMAN; NORMAL VALUE; PARTIAL THROMBOPLASTIN TIME; PHOSPHATE BLOOD LEVEL; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; PROTHROMBIN TIME; RHESUS MONKEY; SODIUM BLOOD LEVEL; SWINE; THROMBOPLASTIN TIME; TRANSGENIC PIG; TRIACYLGLYCEROL BLOOD LEVEL; UREA BLOOD LEVEL; WILD TYPE; XENOTRANSPLANTATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOOD COAGULATION; GALACTOSYLTRANSFERASES; GENE KNOCKOUT TECHNIQUES; GENETIC ENGINEERING; GRAFT REJECTION; HUMANS; PRIMATES; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84870492437     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/xen.12007     Document Type: Article

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