Characterization of a CD46 transgenic pig and protection of transgenic kidneys against hyperacute rejection in non-immunosuppressed baboons

Xenotransplantation

Volumn 11, Issue 2, 2004, Pages 171-183

  Loveland, Bruce E ^a   Milland, Julie ^a   Kyriakou, Peter ^a   Thorley, Bruce R ^a   Christiansen, Dale ^a   Lanteri, Marc B ^a   Van Regensburg, Mark ^b   Duffield, Maureen ^b   French, Andrew J ^c   Williams, Lindsay ^c   Baker, Louise ^d   Brandon, Malcolm R ^d   Xing, Pei Xiang ^a   Kahn, Del ^b   McKenzie, Ian F C ^a  

^a AUSTIN RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c MONASH UNIVERSITY   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Complement regulation; Human membrane cofactor protein; Hyperacute rejection; Minigene; Transgenic; Xenotransplantation

Indexed keywords

ANTIBODY; GALACTOSYLGALACTOSE; MEMBRANE COFACTOR PROTEIN;

ADOLESCENT; ANIMAL CELL; ANIMAL TISSUE; ANTIBODY DEPENDENT LYMPHOCYTOTOXICITY; ANTIBODY TITER; ANTIGEN EXPRESSION; ARTICLE; BABOON; BLOOD CLOTTING DISORDER; COMPLEMENT ACTIVATION; COMPLEMENT DEPENDENT CYTOTOXICITY; COMPLEMENT DEPOSITION; CONTROLLED STUDY; FLOW CYTOMETRY; FOCAL KIDNEY TUBULE INFARCTION; GENE; GENETIC TRANSFECTION; GRAFT SURVIVAL; HETEROTOPIC TRANSPLANTATION; HISTOPATHOLOGY; HYPERACUTE GRAFT REJECTION; IMMUNOCOMPETENCE; IMMUNOGLOBULIN DEPOSITION; KIDNEY GRAFT; KIDNEY INFARCTION; KIDNEY TRANSPLANTATION; KIDNEY TUBULE; KIDNEY XENOTRANSPLANTATION; LEUKOCYTE ADHERENCE; LYMPHOCYTE; LYMPHOCYTIC INFILTRATION; MINIGENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SWINE; TISSUE DISTRIBUTION; TRANSGENE; TRANSGENIC ANIMAL; TRANSGENIC SWINE; VASCULAR ENDOTHELIUM; XENOGRAFT; XENOTRANSPLANTATION;

EID: 10744224843     PISSN: 0908665X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1399-3089.2003.00103_11_2.x     Document Type: Article

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