Dual role of insulin-like growth factor-1 in acetyl-CoA carboxylase-alpha activity in human colon cancer cells HCT-8: Downregulating its expression and phosphorylation

Molecular and Cellular Biochemistry

Volumn 357, Issue 1-2, 2011, Pages 255-262

  Luo, Di Xian ^a,b,c   Peng, Xu Hong ^d   Xiong, Yan ^a,e   Liao, Duan Fang ^c,f   Cao, Deliang ^b   Li, Longjiang ^g  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SOUTH CHINA   (China)

^d THE FIRST PEOPLE S HOSPITAL OF CHENZHOU   (China)

^e GUANGZHOU MEDICAL UNIVERSITY   (China)

^f HUNAN UNIVERSITY OF CHINESE MEDICINE   (China)

^g People s Hospital of Baoan   (China)

Author keywords

Acetyl CoA carboxylase ; AMPK; ERK1 2; Fatty acid lipid synthesis; HCT 8 cells; Insulin like growth factor 1

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ACETYL COENZYME A CARBOXYLASE ALPHA; FATTY ACID; LIGASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN P53; SOMATOMEDIN C; UNCLASSIFIED DRUG; ACETYL COENZYME A CARBOXYLASE; ATM PROTEIN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; FLAVONOID; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL COUNT; CELL PROLIFERATION; COLON CANCER; CULTURE MEDIUM; DOWN REGULATION; ENZYME ACTIVITY; FATTY ACID SYNTHESIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LIPOGENESIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; BIOSYNTHESIS; CELL SURVIVAL; COLON TUMOR; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHOSPHORYLATION; TUMOR CELL LINE;

ACETYL-COA CARBOXYLASE; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; COLONIC NEOPLASMS; CULTURE MEDIA, SERUM-FREE; DNA-BINDING PROTEINS; FATTY ACIDS; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MAP KINASE SIGNALING SYSTEM; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84870410327     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-0896-0     Document Type: Article

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