Formation of methotrexate-PLLA-PEG-PLLA composite microspheres by microencapsulation through a process of suspension-enhanced dispersion by supercritical CO2

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 3013-3022

  Chen, Ai Zheng ^a   Wang, Guang Ya ^a   Wang, Shi Bin ^a   Li, Li ^a   Liu, Yuan Gang ^a   Zhao, Chen ^a  

^a HUAQIAO UNIVERSITY   (China)

Author keywords

Drug loading; Encapsulation efficiency; Methotrexate; Nanoparticles; Poly(L lactide); Supercritical CO2 sustained release

Indexed keywords

CARBON DIOXIDE; METHOTREXATE; MICROSPHERE; POLY(LEVO LACTIDE)POLY(ETHYLENE GLYCOL)POLY(LEVO LACTIDE); POLYMER; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL PARAMETERS; CONTROLLED STUDY; DISPERSION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG LOADING; ENCAPSULATION EFFICIENCY; INFRARED SPECTROSCOPY; MICROENCAPSULATION; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; SUSPENSION ENHANCED DISPERSION; SUSTAINED DRUG RELEASE;

CARBON DIOXIDE; CHEMICAL PRECIPITATION; LACTATES; METHOTREXATE; NANOCAPSULES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; SURFACE PROPERTIES; SUSPENSIONS;

EID: 84870328222     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S32662     Document Type: Article

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