Supercritical fluid assisted atomization introduced by an enhanced mixer for micronization of lysozyme: Particle morphology, size and protein stability

International Journal of Pharmaceutics

Volumn 421, Issue 2, 2011, Pages 258-268

  Du, Zhe ^a   Guan, Yi Xin ^a   Yao, Shan Jing ^a   Zhu, Zi Qiang ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Bio activity; Hydrodynamic cavitation mixer; Lysozyme; Micronization; Supercritical fluid assisted atomization

Indexed keywords

CARBON DIOXIDE; LYSOZYME; WATER;

ARTICLE; HYDRODYNAMIC CAVITATION MIXER; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; MIXER; NEBULIZATION; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN STABILITY; SUPERCRITICAL FLUID ASSISTED ATOMIZATION; X RAY DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; CARBON DIOXIDE; DRUG COMPOUNDING; ETHANOL; MICROCOCCUS; MICROSCOPY, ELECTRON, SCANNING; MURAMIDASE; PARTICLE SIZE; POWDER DIFFRACTION; PRESSURE; PROTEIN STABILITY; SOLVENTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TEMPERATURE; THERMOGRAVIMETRY; WATER; X-RAY DIFFRACTION;

EID: 81755165860     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.10.002     Document Type: Article

References (33)

1. R. Adami, L.S. Osséo, and E. Reverchon Micronization of lysozyme by supercritical assisted atomization Biotechnol. Bioeng. 104 2009 1162 1170
2. M.Q. Cai, Y.X. Guan, S.J. Yao, and Z.Q. Zhu Supercritical fluid assisted atomization introduced by hydrodynamic cavitation mixer (SAA-HCM) for micronization of levofloxacin hydrochloride J. Supercrit. Fluids 43 2008 524 534
3. C.J. Chang, and A.D. Randolph Precipitation of microsize organic particles from supercritical fluids AlChE J. 35 1989 1876 1882
4. S.C. Chang, M.J. Lee, and H.M. Lin Role of phase behavior in micronization of lysozyme via a supercritical anti-solvent process Chem. Eng. J. 139 2008 416 425
5. A. Dong, P. Huang, and W.S. Caughey Protein secondary structures in water from second-derivative amide I infrared spectra Biochemistry (Mosc) 29 1990 3303 3308
6. A.C. Dong, S.J. Prestrelski, S.D. Allison, and J.F. Carpenter Infrared spectroscopic studies of lyophilization-induced and temperature-induced protein aggregation J. Pharm. Sci. 84 1995 415 424
7. F.N. Fu, D.B. Deoliveira, W.R. Trumble, H.K. Sarkar, and B.R. Singh Secondary structure estimation of proteins using the amide-III region of Fourier transform infrared spectroscopy: application to analyze calcium-binding-induced structural changes in calsequestrin Appl. Spectrosc. 48 1994 1432 1441
8. J. Kerc, S. Srcic, Z. Knez, and P. Sencar-Bozic Micronization of drugs using supercritical carbon dioxide Int. J. Pharm. 182 1999 33 39
9. Z.Y. Li, J.Z. Jiang, X.W. Liu, H.H. Tang, and W. Wei Experimental investigation on the micronization of aqueous cefadroxil by supercritical fluid technology J. Supercrit. Fluids 48 2009 247 252
10. D.W. Matson, J.L. Fulton, R.C. Petersen, and R.D. Smith Rapid expansion of supercritical fluid solutions: solute formation of powders, thin films, and fibers Ind. Eng. Chem. Res. 26 1987 2298 2306
11. S.F. Miao, J.P. Yu, Z. Du, Y.X. Guan, S.J. Yao, and Z.Q. Zhu Supercritical fluid extraction and micronization of ginkgo flavonoids from ginkgo biloba leaves Ind. Eng. Chem. Res. 49 2010 5461 5466
12. G. Muhrer, and M. Mazzotti Precipitation of lysozyme nanoparticles from dimethyl sulfoxide using carbon dioxide as antisolvent Biotechnol. Prog. 19 2003 549 556
13. H.G. Nagendra, N. Sukumar, and M. Vijayan Role of water in plasticity, stability, and action of proteins: the crystal structures of lysozyme at very low levels of hydration Proteins 32 1998 229 240
14. J.S. Patton, and P.R. Byron Inhaling medicines: delivering drugs to the body through the lungs Nat. Rev. Drug Discov. 6 2007 67 74
15. R.D. Reitz, and F.V. Bracco Mechanism of atomization of a liquid jet Phys. Fluids 25 1982 1730 1742
16. E. Reverchon Supercritical antisolvent precipitation of micro- and nano-particles J. Supercrit. Fluids 15 1999 1 21
17. E. Reverchon Supercritical-assisted atomization to produce micro- and/or nanoparticles of controlled size and distribution Ind. Eng. Chem. Res. 41 2002 2405 2411
18. E. Reverchon Terbutaline microparticles suitable for aerosol delivery produced by supercritical assisted atomization Int. J. Pharm. 258 2003 1 9
19. E. Reverchon Erythromycin micro-particles produced by supercritical fluid atomization Powder Technol. 141 2004 100 108
20. E. Reverchon, and A. Antonacci Chitosan microparticles production by supercritical fluid processing Ind. Eng. Chem. Res. 45 2006 5722 5728
21. E. Reverchon, and G. Della Porta Micronization of antibiotics by supercritical assisted atomization J. Supercrit. Fluids 26 2003 243 252
22. M.A. Rodrigues, J. Li, L. Padrela, A. Almeida, H.A. Matos, and E.G. de Azevedo Anti-solvent effect in the production of lysozyme nanoparticles by supercritical fluid-assisted atomization processes J. Supercrit. Fluids 48 2009 253 260
23. 2-assisted aerosolization J. Pharm. Sci. 90 2001 785 797
24. 2 Int. J. Pharm. 148 1997 123 130
25. 2 at high temperatures and pressures Am. J. Sci. 262 1964 1055 1074
26. 2 - influence on SFE of organics and metal-chelates Anal. Chem. 67 1995 4040 4043
27. M. van de Weert, L. Jorgensen, E. Horn Moeller, and S. Frokjaer Factors of importance for a successful delivery system for proteins Expert Opin. Drug Deliv. 2 2005 1029 1037
28. Q. Wang, Y.X. Guan, S.J. Yao, and Z.Q. Zhu Microparticle formation of sodium cellulose sulfate using supercritical fluid assisted atomization introduced by hydrodynamic cavitation mixer Chem. Eng. J. 159 2010 220 229
29. R. Wiebe The binary system carbon dioxide-water under pressure Chem. Rev. 29 1941 475 481
30. R. Wiebe, and V.L. Gaddy The solubility in water of carbon dioxide at 50, 75 and 100 degrees, at pressures to 700 atmospheres J. Am. Chem. Soc. 61 1939 315 318
31. C.J. Yan, M.Z. Xie, and P.H. Yin Mechanisms of breakup and atomization of a viscous liquid jet in a viscous gas Acta Aerodyn. Sin. 22 2004 422 426
32. M. Yang, S. Velaga, H. Yamamoto, H. Takeuchi, Y. Kawashima, L. Hovgaard, M. Vandeweert, and S. Frokjaer Characterisation of salmon calcitonin in spray-dried powder for inhalation: effect of chitosan Int. J. Pharm. 331 2007 176 181
33. S.D. Yeo, G.B. Lim, P.G. Debenedetti, and H. Bernstein Formation of microparticulate protein powders using a supercritical fluid antisolvent Biotechnol. Bioeng. 41 1993 341 346