Co-encapsulation of magnetic nanoparticles and doxorubicin into biodegradable microcarriers for deep tissue targeting by vascular MRI navigation

Biomaterials

Volumn 32, Issue 13, 2011, Pages 3481-3486

  Pouponneau, Pierre ^a,b   Leroux, Jean Christophe ^b,c   Soulez, Gilles ^d   Gaboury, Louis ^e   Martel, Sylvain ^a  

^a ÉCOLE POLYTECHNIQUE DE MONTRÉAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c ETH ZURICH   (Switzerland)

^d CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^e INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

Drug delivery; Liver; Magnetism; Microencapsulation; MRI (magnetic resonance imaging); Nanoparticle

Indexed keywords

BIODEGRADABLE MICROPARTICLES; CO-ENCAPSULATION; CYTOTOXIC AGENTS; DOXORUBICIN; DRUG-TARGETING; EMBOLIZATION; ENDOVASCULAR; HEPATIC ARTERY; HIGH-SATURATION MAGNETIZATION; IN-VITRO; IN-VIVO; IRON-COBALT; LIVER LOBE; MAGNETIC FIELD MAGNITUDES; MAGNETIC GRADIENT; MAGNETIC MICROCARRIERS; MAGNETIC NANOPARTICLES; MICROCARRIERS; MICROENCAPSULATION; MRI (MAGNETIC RESONANCE IMAGING); PRECLINICAL STUDIES; PROOF OF CONCEPT; RABBIT MODELS; SIDE EFFECT; STRONG CONTRAST; SUSTAINED RELEASE; TUMOR CELLS; TUMOR TARGETING;

BLOOD VESSELS; COBALT; DRUG DELIVERY; ENCAPSULATION; HISTOLOGY; LIVER; MAGNETIC FIELDS; MAGNETIC RESONANCE IMAGING; MAGNETS; NANOPARTICLES; NAVIGATION; PACKAGING; RESONANCE; SATURATION MAGNETIZATION; TUMORS;

NANOMAGNETICS;

COBALT; DOXORUBICIN; IRON;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMOEMBOLIZATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG TARGETING; EXPERIMENTAL RABBIT; FLOW RATE; HEPATIC ARTERY; IN VITRO STUDY; IN VIVO STUDY; LIVER; LIVER LEVEL; MAGNETIC RESONANCE NAVIGATION; NANOENCAPSULATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE;

ANIMALS; DOXORUBICIN; DRUG DELIVERY SYSTEMS; LIVER; MAGNETIC RESONANCE IMAGING; MAGNETICS; NANOPARTICLES; RABBITS;

ORYCTOLAGUS CUNICULUS;

EID: 79952002609     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.12.059     Document Type: Article

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