Precipitation of tretinoin and acetaminophen with solution enhanced dispersion by supercritical fluids (SEDS). Role of phase equilibria to optimize particle diameter

Powder Technology

Volumn 217, Issue , 2012, Pages 177-188

  Tabernero, Antonio ^a   Martín del Valle, Eva M ^a   Galán, Miguel A ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Acetaminophen; Phase equilibria; SEDS; Tretinoin

Indexed keywords

ACETAMINOPHEN; ANTI-SOLVENTS; BINARY SYSTEMS; COSOLVENT EFFECTS; EFFECT OF PRESSURE; EQUILIBRIUM DIAGRAMS; EXPERIMENTAL CONDITIONS; MICRO-PARTICLES; MIXTURE CRITICAL POINT; PARTICLE DIAMETERS; PENG-ROBINSON EQUATION OF STATE; PRECIPITATION PROCESS; SEDS; SOLUTION CONCENTRATION; SOLUTION ENHANCED DISPERSION BY SUPERCRITICAL FLUIDS; SUPER-CRITICAL; TRETINOIN; VAPOR-LIQUID;

BINARY MIXTURES; CARBON DIOXIDE; DISPERSIONS; EFFLUENT TREATMENT; EQUATIONS OF STATE; ETHANOL; ORGANIC SOLVENTS; PARTICLE SIZE; PRECIPITATION (CHEMICAL); SOLVENTS; SUPERCRITICAL FLUID EXTRACTION; SUPERCRITICAL FLUIDS; SUPERSATURATION;

PHASE EQUILIBRIA;

ALCOHOL; CARBON DIOXIDE; PARACETAMOL; RETINOIC ACID;

ARTICLE; CONCENTRATION (PARAMETERS); PARTICLE SIZE; PHASE EQUILIBRIA; PHYSICAL PHENOMENA; PRECIPITATION; PRESSURE; SOLUTION ENHANCED DISPERSION BY SUPERCRITICAL FLUID; SOLVENT EFFECT; STATISTICAL ANALYSIS; SUPERCRITICAL FLUID; TEMPERATURE;

EID: 84855215062     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2011.10.025     Document Type: Article

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