Bone marrow stromal cells from aged male rats have delayed mineralization and reduced response to mechanical stimulation through nitric oxide and ERK1/2 signaling during osteogenic differentiation

Biogerontology

Volumn 13, Issue 5, 2012, Pages 467-478

  Joiner, Danese M ^a,b   Tayim, Riyad J ^a   Kadado, Allen ^a   Goldstein, Steven A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b VAN ANDEL RESEARCH INSTITUTE   (United States)

Author keywords

Age; ERK1 2; Marrow stromal cell; Mechanotransduction; Nitric oxide; Osteoporosis

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 1; NITRIC OXIDE;

AGING; ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MARROW STROMAL CELL; BONE MINERALIZATION; CELL STIMULATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; MALE; MECHANICAL STIMULATION; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; STROMA CELL;

AGING; ANIMALS; BASE SEQUENCE; BONE AND BONES; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; DNA PRIMERS; MALE; MAP KINASE SIGNALING SYSTEM; MECHANOTRANSDUCTION, CELLULAR; MESENCHYMAL STROMAL CELLS; NITRIC OXIDE; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84870291058     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-012-9391-6     Document Type: Article

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