Reduced concentration of collagen reducible cross links in human trabecular bone with respect to age and osteoporosis

Bone

Volumn 19, Issue 5 SUPPL., 1996, Pages 479-484

  Oxlund, H ^a   Mosekilde, Li ^a   Ortoft G ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Bone collagen; Collagen cross links; Collagen extractability; Lysyl oxidase; Osteoporosis; Pyridinoline

Indexed keywords

ACETIC ACID; COLLAGEN; PEPSIN A; PYRIDINE DERIVATIVE; PYRIDINIUM DERIVATIVE;

ADOLESCENT; ADULT; AGED; AGING; ANALYTIC METHOD; ARTICLE; AUTOPSY; BONE MASS; BONE STRENGTH; CANCELLOUS BONE; CHEMICAL STRUCTURE; CONTROLLED STUDY; CROSS LINKING; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; ION EXCHANGE CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MALE; OSTEOPOROSIS; TRABECULAR BONE;

ACETIC ACID; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; AMINO ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; COLLAGEN; DIPEPTIDES; FEMALE; HUMANS; LUMBAR VERTEBRAE; MALE; MIDDLE AGED; OSTEOPOROSIS; PEPSIN A; PYRIDINIUM COMPOUNDS; REPRODUCIBILITY OF RESULTS;

EID: 0029955513     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(96)00283-9     Document Type: Article

References (28)

1. Bailey, A. J., Peach, C. M., and Fowler, L. J. Chemistry of the collagen crosslinks. Isolation and characterization of two intermediate intermolecular crosslinks in collagen. Biochem J 117:819-831; 1970.
2. Bailey, A. J., Robins, S. P., and Balian, G. Biological significance of the intermolecular crosslinks of collagen. Nature 251:105-109; 1974.
3. Bailey, A. J., Wotton, S. F., Sims, T. J., and Thompson, P. W. Biochemical changes in the collagen of human osteoporotic bone matrix. Connect Tissue Res 29:119-132; 1993.
4. Bätge, B., Notbohm, H., Diebold, J., Lehmann, H., Bodo, M., Deutzmann, R., and Müller, P. K. A critical crosslink region in human-bone-derived collagen type I. Specific cleavage site at residue Leu95. Eur J Biochem 192:153-159; 1990.
5. Danielsen, C. C., Andreassen, T. T., and Mosekilde, Li. Mechanical properties of collagen from decalcified rat femur in relation to age and in vitro maturation. Calcif Tissue Int 39:69-73; 1986.
6. Eyre, D. R. Cross-linking in collagen and elastin. Ann Rev Biochem 53:717-748; 1984.
7. Eyre, D. R. Collagen cross-linking amino acids. Methods Enzymol 144:115-139; 1987.
8. Eyre, D. R., Dickson, I. R., and Vann Ness, K. Collagen cross-linking in human bone and articular cartilage. Age-related changes in the content of mature hydroxypyridinium residues. Biochem J 252:495-500; 1988.
9. Glimcher, M. J. and Krane, S. M. The organization and structure of bone, and the mechanism of calcification. In: Gould, B. S., Ed. Treatise on collagen. London: Academic; 1968; part B, 68-251.
10. Heinrikson, R. L. and Meredith, S. C. Amino acid analysis by reversed-phase high performance liquid chromatography. Anal Biochem 136:65-74; 1984.
11. Mosekilde, Li. and Mosekilde. Le. Normal vertebral size and compressive strength: relations to age, and to vertebral and iliac trabecular bone compressive strength. Bone 7:207-212; 1986.
12. Mosekilde, Li., Mosekilde, Le., and Danielsen, C. C. Biomechanical competence of vertebral trabecular bone in relation to ash density and age in normal individuals. Bone 8:79-85; 1987.
13. Mosekilde, Li. Age-related changes in vertebral trabecular bone architecture-assessed by a new method. Bone 9:247-250; 1988.
14. Mosekilde, Li. Sex differences in age-related loss of vertebral trabecular bone mass and structure-biomechanical consequences. Bone 10:425-432; 1989.
15. Mosekilde, Li. Consequences of the remodelling process for vertebral trabecular bone structure: a scanning electron microscopy study (uncoupling of unloaded structures). Bone Miner 10:13-35; 1990.
16. Mosekilde, Li. Vertebral structure and strength in vivo and in vitro. Calcif Tissue Int 53:5121-5126; 1993.
17. Oxlund, H., Sims, T., and Light, N. D. Changes in mechanical properties, thermal stability, reducible cross-links and glycosyl-lysines in rat skin induced by corticosteroid treatment. Acta Endocrinol 101:312-320; 1982.
18. Oxlund, H., Mosekilde, Li., and Ørtoft, G. Alterations in the stability of collagen from human trabecular bone with respect to age. In: Christiansen, C, Johansen, J. S., and Riis, B. J., Eds. Osteoporosis. Copenhagen: Osteopress ApS; 1987; 313-316.
19. Oxlund, H. and Andreassen, T. T. Aminoguanidine treatment reduces the increase in collagen stability of rats with experimental diabetes mellitus. Diabetologia 35:19-25; 1992.
20. Oxlund, H., Ejersted, C., Andreassen, T. T., Tørrring, O., and Nilsson, M.H. L. Parathyroid hormone (1-34) and (1-84) stimulate cortical bone formation both from periosteum and endosteum. Calcif Tissue Int 53:394-399; 1993.
21. Oxlund, H., Barckman, M., Ørtoft, G., and Andreassen, T. T Reduced concentrations of collagen cross-links are associated with reduced strength of bone. Bone 17:3658-3715; 1995.
22. Parfitt, A. M. Bone remodeling and bone loss: Understanding the pathophysiology of osteoporosis. Clin Obstet Gynecol 30:789-811; 1987.
23. Robins, S. P. and Bailey, A. J. The chemistry of the collagen cross-links. Characterization of the products of reduction of skin, tendon and bone with sodium cyanoborohydride. Biochem J 163:339-346; 1977.
24. Siegel, R. C. and Fu, J. C. C. Collagen cross-linking. Purification and substrate specificity of lysyl oxidase. J Biol Chem 251:5779-5785; 1976.
25. Siegel, R. C., Fu, J. C. C., Uto, N., Horiuchi, K., and Fujimoto, D. Collagen cross-linking: lysyl oxidase dependent synthesis of pyridinoline in vitro: confirmation that pyridinoline is derived from collagen. Biochem Biophys Res Commun 108:1546-1550; 1982.
26. Sokal, R. R. and Rohlf, F. J. Biometry. San Francisco: Freeman; 1981; 429-447.
27. Woessner, J. F. Determination of hydroxyproline in connective tissues. In: Hall, D. A., Ed. The Methodology of Connective Tissue Research. Oxford: Joynson-Bruvvers; 1976; 227-233.
28. Yamauchi, M. and Mechanic, G. L. Cross-linking of collagen. In: Nimni, M. E., Ed. Collagen. Vol 1. Biochemistry. Boca Raton: CRC; 1988; 157-172.