메뉴 건너뛰기




Volumn 61, Issue 1, 2013, Pages 1-10

Ts6 and Ts2 from Tityus serrulatus venom induce inflammation by mechanisms dependent on lipid mediators and cytokine production

Author keywords

Cytokines; Inflammation; Leukotriene; Prostaglandin; Ts2; Ts6

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; CELECOXIB; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; LEUKOTRIENE B4; PROSTAGLANDIN E2; PROTEIN; TITYUS SERRULATUS 2; TITYUS SERRULATUS 6; TITYUS TOXIN; UNCLASSIFIED DRUG;

EID: 84870191662     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2012.10.002     Document Type: Article
Times cited : (42)

References (51)
  • 1
    • 46649112693 scopus 로고    scopus 로고
    • Pathophysiological effects of Androctonus australis hector scorpion venom: tissue damages and inflammatory response
    • Adi-Bessalem S., Hammoudi-Triki D., Laraba-Djebari F. Pathophysiological effects of Androctonus australis hector scorpion venom: tissue damages and inflammatory response. Exp. Toxicol. Pathol. 2008, 60(4-5):373-380.
    • (2008) Exp. Toxicol. Pathol. , vol.60 , Issue.4-5 , pp. 373-380
    • Adi-Bessalem, S.1    Hammoudi-Triki, D.2    Laraba-Djebari, F.3
  • 2
    • 0024384144 scopus 로고
    • A simplified procedure for the fractionalization of Tityus serrulatus venom: isolation and partial characterization of TsTX-IV, a new neurotoxin
    • Arantes E.C., Prado W.A., Sampaio S.V., Giglio J.R. A simplified procedure for the fractionalization of Tityus serrulatus venom: isolation and partial characterization of TsTX-IV, a new neurotoxin. Toxicon 1989, 8:907-916.
    • (1989) Toxicon , vol.8 , pp. 907-916
    • Arantes, E.C.1    Prado, W.A.2    Sampaio, S.V.3    Giglio, J.R.4
  • 3
    • 0037452612 scopus 로고    scopus 로고
    • Differential effects of prostaglandin derived from omega-6 and omega-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion
    • 18
    • Bagga D., Wang L., Farias-Eisner R., Glaspy J.A., Reddy S.T. Differential effects of prostaglandin derived from omega-6 and omega-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion. Proc. Natl. Acad. Sci. U. S. A. 2003, 100(4):1751-1756. 18.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , Issue.4 , pp. 1751-1756
    • Bagga, D.1    Wang, L.2    Farias-Eisner, R.3    Glaspy, J.A.4    Reddy, S.T.5
  • 4
    • 77956494550 scopus 로고    scopus 로고
    • Understanding the molecular mechanisms of the multifaceted IL-10-mediated anti-inflammatory response: lessons from neutrophils
    • Bazzoni F., Tamassia N., Rossato M., Cassatella M.A. Understanding the molecular mechanisms of the multifaceted IL-10-mediated anti-inflammatory response: lessons from neutrophils. Eur. J. Immunol. 2010, 40:2360-2368.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 2360-2368
    • Bazzoni, F.1    Tamassia, N.2    Rossato, M.3    Cassatella, M.A.4
  • 5
    • 0031172513 scopus 로고    scopus 로고
    • Toxins and genes isolated from Scorpions of the genus Tityus
    • Becerril B., Marangoni S., Possani L.D. Toxins and genes isolated from Scorpions of the genus Tityus. Toxicon 1997, 35(6):821-835.
    • (1997) Toxicon , vol.35 , Issue.6 , pp. 821-835
    • Becerril, B.1    Marangoni, S.2    Possani, L.D.3
  • 6
    • 0033731909 scopus 로고    scopus 로고
    • Molecular mechanisms of neurotoxin action on voltage-gated sodium channels
    • Cestèle S., Catterall W.A. Molecular mechanisms of neurotoxin action on voltage-gated sodium channels. Biochimie 2000, 82:883-892.
    • (2000) Biochimie , vol.82 , pp. 883-892
    • Cestèle, S.1    Catterall, W.A.2
  • 9
    • 79959376112 scopus 로고    scopus 로고
    • Purification and characterization of Ts15, the first member of a new α-KTX subfamily from the venom of the Brazilian scorpion Tityus serrulatus
    • Cologna C.T., Tytgat J., Peigneur S., Rosa J.C., Selistre-de-Araujo H.S., Varanda W.A., Arantes E.C. Purification and characterization of Ts15, the first member of a new α-KTX subfamily from the venom of the Brazilian scorpion Tityus serrulatus. Toxicon 2011, 58:54-61.
    • (2011) Toxicon , vol.58 , pp. 54-61
    • Cologna, C.T.1    Tytgat, J.2    Peigneur, S.3    Rosa, J.C.4    Selistre-de-Araujo, H.S.5    Varanda, W.A.6    Arantes, E.C.7
  • 10
    • 84859606337 scopus 로고    scopus 로고
    • Investigation of the relationship between structure and function of Ts2, a neurotoxin from Tityus serrulatus venom
    • Cologna C.T., Peigneur S., Rustiguel J.K., Nonato M.C., Tytgat J., Arantes E.C. Investigation of the relationship between structure and function of Ts2, a neurotoxin from Tityus serrulatus venom. FEBS J. 2012, 279:1495-1504.
    • (2012) FEBS J. , vol.279 , pp. 1495-1504
    • Cologna, C.T.1    Peigneur, S.2    Rustiguel, J.K.3    Nonato, M.C.4    Tytgat, J.5    Arantes, E.C.6
  • 11
    • 0037305964 scopus 로고    scopus 로고
    • Disulfide bridges and blockage of Shaker B K(+)-channels by another butantoxin peptide purified from the Argentinean scorpion Tityus trivittatus
    • Coronas F.V., de Roodt A.R., Portugal T.O., Zamudio F.Z., Batista C.V., Gómez-Lagunas F., Possani L.D. Disulfide bridges and blockage of Shaker B K(+)-channels by another butantoxin peptide purified from the Argentinean scorpion Tityus trivittatus. Toxicon 2003, 2:173-179.
    • (2003) Toxicon , vol.2 , pp. 173-179
    • Coronas, F.V.1    de Roodt, A.R.2    Portugal, T.O.3    Zamudio, F.Z.4    Batista, C.V.5    Gómez-Lagunas, F.6    Possani, L.D.7
  • 12
    • 0036708950 scopus 로고    scopus 로고
    • Sympathetic nervous system activation, antivenin administration and cardiovascular manifestations of scorpion envenomation
    • Dàvila C.A.M., Dàvila D.F., Donis J.H., Bellabarba G.A., Villarreal V., Barboza J.S. Sympathetic nervous system activation, antivenin administration and cardiovascular manifestations of scorpion envenomation. Toxicon 2002, 40:1339-1346.
    • (2002) Toxicon , vol.40 , pp. 1339-1346
    • Dàvila, C.A.M.1    Dàvila, D.F.2    Donis, J.H.3    Bellabarba, G.A.4    Villarreal, V.5    Barboza, J.S.6
  • 13
  • 15
    • 34547924047 scopus 로고    scopus 로고
    • The snake venom metalloproteinase BaP1 induces joint hypernociception through TNF-alpha and PGE2-dependent mechanisms
    • Fernandes C.M., Pereira Teixeira C.deF., Leite A.C., Gutiérrez J.M., Rocha F.A. The snake venom metalloproteinase BaP1 induces joint hypernociception through TNF-alpha and PGE2-dependent mechanisms. Br. J. Pharmacol. 2007, 151(8):1254-1261.
    • (2007) Br. J. Pharmacol. , vol.151 , Issue.8 , pp. 1254-1261
    • Fernandes, C.M.1    Pereira Teixeira, C.2    Leite, A.C.3    Gutiérrez, J.M.4    Rocha, F.A.5
  • 16
    • 0019311062 scopus 로고
    • Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes
    • Ford-Hutchinson A.W., Bray M.A., Doig M.V., Shipley M.E., Smith M.J. Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature 1980, 286(5770):264-265.
    • (1980) Nature , vol.286 , Issue.5770 , pp. 264-265
    • Ford-Hutchinson, A.W.1    Bray, M.A.2    Doig, M.V.3    Shipley, M.E.4    Smith, M.J.5
  • 17
    • 0037212642 scopus 로고    scopus 로고
    • Increased plasma levels of IL-1β, IL-6, IL-8, IL-10 and TNF-α in patients moderately or severely envenomed by Tityus serrulatus scorpion sting
    • Fukuhara Y.D., Reis M.L., Dellalibera-Joviliano R., Cunha F.Q., Donadi E.A. Increased plasma levels of IL-1β, IL-6, IL-8, IL-10 and TNF-α in patients moderately or severely envenomed by Tityus serrulatus scorpion sting. Toxicon 2003, 41(1):49-55.
    • (2003) Toxicon , vol.41 , Issue.1 , pp. 49-55
    • Fukuhara, Y.D.1    Reis, M.L.2    Dellalibera-Joviliano, R.3    Cunha, F.Q.4    Donadi, E.A.5
  • 18
    • 0035976575 scopus 로고    scopus 로고
    • Prostaglandins and leukotrienes: advances in eicosanoid biology
    • Funk C.D. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science 2001, 294:1871-1885.
    • (2001) Science , vol.294 , pp. 1871-1885
    • Funk, C.D.1
  • 21
  • 22
    • 0025164256 scopus 로고
    • Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases
    • Lewis R.A., Austen K.F., Soberman R.J. Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases. N. Engl. J. Med. 1990, 323:645-655.
    • (1990) N. Engl. J. Med. , vol.323 , pp. 645-655
    • Lewis, R.A.1    Austen, K.F.2    Soberman, R.J.3
  • 24
    • 0027028064 scopus 로고
    • The beta-type toxin Ts II from the scorpion Tityus serrulatus: amino acid sequence determination and assessment of biological and antigenic properties
    • Mansuelle P., Martin-Eauclaire M.F., Chavez-Olortegui C., de Lima M.E., Rochat H., Granier C. The beta-type toxin Ts II from the scorpion Tityus serrulatus: amino acid sequence determination and assessment of biological and antigenic properties. Nat. Toxins. 1992, 1(2):119-125.
    • (1992) Nat. Toxins. , vol.1 , Issue.2 , pp. 119-125
    • Mansuelle, P.1    Martin-Eauclaire, M.F.2    Chavez-Olortegui, C.3    de Lima, M.E.4    Rochat, H.5    Granier, C.6
  • 25
    • 0032707758 scopus 로고    scopus 로고
    • Leukotrienes are involved in leukocyte recruitment induced by live Histoplasma capsulatum or by the beta-glucan present in their cell wall
    • Medeiros A.I., Silva C.L., Malheiro A., Maffei C.M., Faccioli L.H. Leukotrienes are involved in leukocyte recruitment induced by live Histoplasma capsulatum or by the beta-glucan present in their cell wall. Br. J. Pharmacol. 1999, 128:1529-1537.
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 1529-1537
    • Medeiros, A.I.1    Silva, C.L.2    Malheiro, A.3    Maffei, C.M.4    Faccioli, L.H.5
  • 26
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov R. Origin and physiological roles of inflammation. Nature 2008, 454:428-435.
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 29
    • 0027200702 scopus 로고
    • Scorpionism in South Africa. A report of 42 serious scorpion envenomations
    • Müller G.J. Scorpionism in South Africa. A report of 42 serious scorpion envenomations. South Afr. Med. J. 1993, 83(6):405-411.
    • (1993) South Afr. Med. J. , vol.83 , Issue.6 , pp. 405-411
    • Müller, G.J.1
  • 32
    • 0032969343 scopus 로고    scopus 로고
    • TsTX-IV, a short chain four-disulfide-bridged neurotoxin from Tityus serrulatus venom which acts on Ca2+-activated K+ channels
    • Novello J.C., Arantes E.C., Varanda W.A., Oliveira B., Giglio J.R., Marangoni S. TsTX-IV, a short chain four-disulfide-bridged neurotoxin from Tityus serrulatus venom which acts on Ca2+-activated K+ channels. Toxicon 1999, 37(4):651-660.
    • (1999) Toxicon , vol.37 , Issue.4 , pp. 651-660
    • Novello, J.C.1    Arantes, E.C.2    Varanda, W.A.3    Oliveira, B.4    Giglio, J.R.5    Marangoni, S.6
  • 35
    • 33748176839 scopus 로고    scopus 로고
    • Mediators involved in the febrile response induced by Tityus serrulatus scorpion venom in rats
    • Pessini A.C., Santos D.R., Arantes E.C., Souza G.E. Mediators involved in the febrile response induced by Tityus serrulatus scorpion venom in rats. Toxicon 2006, 48(5):556-566.
    • (2006) Toxicon , vol.48 , Issue.5 , pp. 556-566
    • Pessini, A.C.1    Santos, D.R.2    Arantes, E.C.3    Souza, G.E.4
  • 36
    • 0034014271 scopus 로고    scopus 로고
    • Intracellular compartmentalization of leukotriene biosynthesis
    • Peters-Golden M., Brock T.G. Intracellular compartmentalization of leukotriene biosynthesis. Am. J. Respir. Crit. Care Med. 2000, 161:36-40.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 36-40
    • Peters-Golden, M.1    Brock, T.G.2
  • 37
    • 34248162309 scopus 로고    scopus 로고
    • Balance between pro- and anti-inflammatory cytokines in mice treated with Centruroides noxius scorpion venom
    • Petricevich V.L. Balance between pro- and anti-inflammatory cytokines in mice treated with Centruroides noxius scorpion venom. Mediators Inflamm. 2006, 2006(6):54273.
    • (2006) Mediators Inflamm. , vol.2006 , Issue.6 , pp. 54273
    • Petricevich, V.L.1
  • 38
    • 77951686254 scopus 로고    scopus 로고
    • Scorpion venom and the inflammatory response
    • (Review)
    • Petricevich V.L. Scorpion venom and the inflammatory response. Mediators Inflamm. 2010, 903295. (Review).
    • (2010) Mediators Inflamm. , pp. 903295
    • Petricevich, V.L.1
  • 39
    • 34548691490 scopus 로고    scopus 로고
    • Toxin gamma from Tityus serrulatus scorpion venom plays an essential role in immunomodulation of macrophages
    • Petricevich V.L., Hernández Cruz A., Coronas F.I., Possani L.D. Toxin gamma from Tityus serrulatus scorpion venom plays an essential role in immunomodulation of macrophages. Toxicon 2007, 50(5):666-675.
    • (2007) Toxicon , vol.50 , Issue.5 , pp. 666-675
    • Petricevich, V.L.1    Hernández Cruz, A.2    Coronas, F.I.3    Possani, L.D.4
  • 40
    • 70449532224 scopus 로고    scopus 로고
    • Inducible transgenes under the control of the hCD68 promoter identifies mouse macrophages with a distribution that differs from the F4/80-and CSF-1R-expressing populations
    • Pillai M.M., Hayes B., Torok-Storb B. Inducible transgenes under the control of the hCD68 promoter identifies mouse macrophages with a distribution that differs from the F4/80-and CSF-1R-expressing populations. Exp. Hematol. 2009, 37(12):1387-1392.
    • (2009) Exp. Hematol. , vol.37 , Issue.12 , pp. 1387-1392
    • Pillai, M.M.1    Hayes, B.2    Torok-Storb, B.3
  • 41
    • 0037330864 scopus 로고    scopus 로고
    • Covalent structure and some pharmacological features of native and cleaved alpha-KTx12-1, a four disulfide-bridged toxin from Tityus serrulatus venom
    • Pimenta A.M., Mansuelle P., Diniz C.R., Martin-Eauclaire M.F. Covalent structure and some pharmacological features of native and cleaved alpha-KTx12-1, a four disulfide-bridged toxin from Tityus serrulatus venom. J. Pept. Sci. 2003, 9(2):132-140.
    • (2003) J. Pept. Sci. , vol.9 , Issue.2 , pp. 132-140
    • Pimenta, A.M.1    Mansuelle, P.2    Diniz, C.R.3    Martin-Eauclaire, M.F.4
  • 42
    • 0025855135 scopus 로고
    • Discharge effect on pancreatic exocrine secretion produced by toxins purified from Tityus serrulatus scorpion venom
    • Possani L.D., Martin B.M., Fletcher M.D., Fletcher P.L. Discharge effect on pancreatic exocrine secretion produced by toxins purified from Tityus serrulatus scorpion venom. J. Biol. Chem. 1991, 5:3178-3185.
    • (1991) J. Biol. Chem. , vol.5 , pp. 3178-3185
    • Possani, L.D.1    Martin, B.M.2    Fletcher, M.D.3    Fletcher, P.L.4
  • 43
    • 0041764556 scopus 로고    scopus 로고
    • Kinetics of cellular responses to intraperitoneal Brugia pahangi infections in normal and immunodeficient mice
    • Ramalingam T., Rajan B., Lee J., Rajan T.V. Kinetics of cellular responses to intraperitoneal Brugia pahangi infections in normal and immunodeficient mice. Infect. Immun. 2003, 71(8):4361-4367.
    • (2003) Infect. Immun. , vol.71 , Issue.8 , pp. 4361-4367
    • Ramalingam, T.1    Rajan, B.2    Lee, J.3    Rajan, T.V.4
  • 45
    • 0029988613 scopus 로고    scopus 로고
    • Interleukin-6 release following scorpion sting in children
    • Sofer S., Gueron M., White R., Lifshitz M., Apte R. Interleukin-6 release following scorpion sting in children. Toxicon 1996, 34:389-392.
    • (1996) Toxicon , vol.34 , pp. 389-392
    • Sofer, S.1    Gueron, M.2    White, R.3    Lifshitz, M.4    Apte, R.5
  • 47
    • 0033594911 scopus 로고    scopus 로고
    • Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclooxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis
    • Warner T.D., Giuliano F., Vojnovic I., Bukasa A., Mitchell J.A., Vane J.R. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclooxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc. Natl. Acad. Sci. U. S. A. 1999, 1999(96):7563-7568.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.1999 , Issue.96 , pp. 7563-7568
    • Warner, T.D.1    Giuliano, F.2    Vojnovic, I.3    Bukasa, A.4    Mitchell, J.A.5    Vane, J.R.6
  • 48
    • 0344440961 scopus 로고    scopus 로고
    • Fatty acids as gatekeepers of immune cell regulation
    • Yaqoob P. Fatty acids as gatekeepers of immune cell regulation. Trends Immunol. 2003, 24:639-645.
    • (2003) Trends Immunol. , vol.24 , pp. 639-645
    • Yaqoob, P.1
  • 49
    • 0033811586 scopus 로고    scopus 로고
    • Characterization and mechanisms of the cardiovascular and haemodynamic alterations induced by scorpion venom in rats
    • Zeghal K., Sahnoun Z., Richer C., Giudicelli J.F. Characterization and mechanisms of the cardiovascular and haemodynamic alterations induced by scorpion venom in rats. Fundam. Clin. Pharmacol. 2000, 14:351-361.
    • (2000) Fundam. Clin. Pharmacol. , vol.14 , pp. 351-361
    • Zeghal, K.1    Sahnoun, Z.2    Richer, C.3    Giudicelli, J.F.4
  • 50
    • 70449502228 scopus 로고    scopus 로고
    • Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils
    • Zhang X., Majlessi L., Deriaud E., Leclerc C., Lo-Man R. Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils. Immunity 2009, 31:761-771.
    • (2009) Immunity , vol.31 , pp. 761-771
    • Zhang, X.1    Majlessi, L.2    Deriaud, E.3    Leclerc, C.4    Lo-Man, R.5
  • 51
    • 79956337354 scopus 로고    scopus 로고
    • Tityus serrulatus venom and toxins Ts1, Ts2 and Ts6 induce macrophage activation and production of immune mediators
    • Zoccal K.F., Bitencourt C.daS., Secatto A., Sorgi C.A., Bordon K., de C., Sampaio S.V., et al. Tityus serrulatus venom and toxins Ts1, Ts2 and Ts6 induce macrophage activation and production of immune mediators. Toxicon 2011, 57:1101-1108.
    • (2011) Toxicon , vol.57 , pp. 1101-1108
    • Zoccal, K.F.1    Bitencourt, C.2    Secatto, A.3    Sorgi, C.A.4    Bordon, K.5    de, C.6    Sampaio, S.V.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.