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Volumn 61, Issue 7, 2012, Pages 1212-1219

Activation of nicotinic acetylcholine receptors on bone marrow-derived cells relieves neuropathic pain accompanied by peripheral neuroinflammation

Author keywords

Chemokine; Cytokine; Macrophage; Neutrophil; Nicotine; Sciatic nerve

Indexed keywords

CHEMOKINE; CYTOKINE; ENHANCED GREEN FLUORESCENT PROTEIN; MECAMYLAMINE; NICOTINE; NICOTINIC RECEPTOR;

EID: 84870063054     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.09.001     Document Type: Article
Times cited : (33)

References (47)
  • 1
    • 33751348539 scopus 로고    scopus 로고
    • Analgesic action of nicotine on tibial nerve transection (TNT)-induced mechanical allodynia through enhancement of the glycinergic inhibitory system in spinal cord
    • M.J. Abdin, N. Morioka, K. Morita, T. Kitayama, S. Kitayama, and T. Nakashima Analgesic action of nicotine on tibial nerve transection (TNT)-induced mechanical allodynia through enhancement of the glycinergic inhibitory system in spinal cord Life Sci. 80 2006 9 16
    • (2006) Life Sci. , vol.80 , pp. 9-16
    • Abdin, M.J.1    Morioka, N.2    Morita, K.3    Kitayama, T.4    Kitayama, S.5    Nakashima, T.6
  • 2
    • 32244442392 scopus 로고    scopus 로고
    • Mechanisms of disease: Neuropathic pain - A clinical perspective
    • R. Baron Mechanisms of disease: neuropathic pain - a clinical perspective Nat. Clin. Pract. Neurol. 2 2006 95 106
    • (2006) Nat. Clin. Pract. Neurol. , vol.2 , pp. 95-106
    • Baron, R.1
  • 3
    • 77955326429 scopus 로고    scopus 로고
    • Neuropathic pain: Diagnosis, pathophysiological mechanisms, and treatment
    • R. Baron, A. Binder, and G. Wasner Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment Lancet Neurol. 9 2010 807 819
    • (2010) Lancet Neurol. , vol.9 , pp. 807-819
    • Baron, R.1    Binder, A.2    Wasner, G.3
  • 4
    • 64849090438 scopus 로고    scopus 로고
    • Bone marrow chimeras and c-fms conditional ablation (Mafia) mice reveal an essential role for resident myeloid cells in lipopolysaccharide/TLR4-induced corneal inflammation
    • H.R. Chinnery, E.C. Carlson, Y. Sun, M. Lin, S.H. Burnett, and V.L. Perez Bone marrow chimeras and c-fms conditional ablation (Mafia) mice reveal an essential role for resident myeloid cells in lipopolysaccharide/TLR4-induced corneal inflammation J. Immunol. 182 2009 2738 2744
    • (2009) J. Immunol. , vol.182 , pp. 2738-2744
    • Chinnery, H.R.1    Carlson, E.C.2    Sun, Y.3    Lin, M.4    Burnett, S.H.5    Perez, V.L.6
  • 5
    • 0031910090 scopus 로고    scopus 로고
    • Antinociceptive responses to nicotinic acetylcholine receptor ligands after systemic and intrathecal administration in mice
    • M.I. Damaj, M. Fei-Yin, M. Dukat, W. Glassco, R.A. Glennon, and B.R. Martin Antinociceptive responses to nicotinic acetylcholine receptor ligands after systemic and intrathecal administration in mice J. Pharmacol. Exp. Ther. 284 1998 1058 1065
    • (1998) J. Pharmacol. Exp. Ther. , vol.284 , pp. 1058-1065
    • Damaj, M.I.1    Fei-Yin, M.2    Dukat, M.3    Glassco, W.4    Glennon, R.A.5    Martin, B.R.6
  • 6
    • 0033626562 scopus 로고    scopus 로고
    • The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model
    • M.I. Damaj, E.M. Meyer, and B.R. Martin The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model Neuropharmacology 39 2000 2785 2791
    • (2000) Neuropharmacology , vol.39 , pp. 2785-2791
    • Damaj, M.I.1    Meyer, E.M.2    Martin, B.R.3
  • 8
    • 27944467013 scopus 로고    scopus 로고
    • Algorithm for neuropathic pain treatment: An evidence based proposal
    • N.B. Finnerup, M. Otto, H.J. McQuay, T.S. Jensen, and S.H. Sindrup Algorithm for neuropathic pain treatment: an evidence based proposal Pain 118 2005 289 305
    • (2005) Pain , vol.118 , pp. 289-305
    • Finnerup, N.B.1    Otto, M.2    McQuay, H.J.3    Jensen, T.S.4    Sindrup, S.H.5
  • 9
    • 77349114869 scopus 로고    scopus 로고
    • Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain
    • B. Gao, M. Hierl, K. Clarkin, T. Juan, H. Nguyen, and M. Valk Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain Pain 149 2010 33 49
    • (2010) Pain , vol.149 , pp. 33-49
    • Gao, B.1    Hierl, M.2    Clarkin, K.3    Juan, T.4    Nguyen, H.5    Valk, M.6
  • 10
    • 77649274037 scopus 로고    scopus 로고
    • Chemokines, neuronal-glial interactions, and central processing of neuropathic pain
    • Y.J. Gao, and R.R. Ji Chemokines, neuronal-glial interactions, and central processing of neuropathic pain Pharmacol Ther. 126 2010 56 68
    • (2010) Pharmacol Ther. , vol.126 , pp. 56-68
    • Gao, Y.J.1    Ji, R.R.2
  • 11
    • 0034795753 scopus 로고    scopus 로고
    • Dorsal root ganglion neurons express multiple nicotinic acetylcholine receptor subtypes
    • J.R. Genzen, W. Van Cleve, and D.S. McGehee Dorsal root ganglion neurons express multiple nicotinic acetylcholine receptor subtypes J. Neurophysiol. 86 2001 1773 1782
    • (2001) J. Neurophysiol. , vol.86 , pp. 1773-1782
    • Genzen, J.R.1    Van Cleve, W.2    McGehee, D.S.3
  • 12
    • 33747422892 scopus 로고    scopus 로고
    • Brain nicotinic acetylcholine receptors: Native subtypes and their relevance
    • C. Gotti, M. Zoli, and F. Clementi Brain nicotinic acetylcholine receptors: native subtypes and their relevance Trends Pharmacol. Sci. 27 2006 482 491
    • (2006) Trends Pharmacol. Sci. , vol.27 , pp. 482-491
    • Gotti, C.1    Zoli, M.2    Clementi, F.3
  • 13
    • 27144464845 scopus 로고    scopus 로고
    • Synergy in cytokine and chemokine networks amplifies the inflammatory response
    • M. Gouwy, S. Struyf, P. Proost, and J. Van Damme Synergy in cytokine and chemokine networks amplifies the inflammatory response Cytokine Growth Factor Rev. 16 2005 561 580
    • (2005) Cytokine Growth Factor Rev. , vol.16 , pp. 561-580
    • Gouwy, M.1    Struyf, S.2    Proost, P.3    Van Damme, J.4
  • 14
    • 65349139499 scopus 로고    scopus 로고
    • The effect of peripherally administered CDP-choline in an acute inflammatory pain model: The role of alpha7 nicotinic acetylcholine receptor
    • M.S. Gurun, R. Parker, J.C. Eisenach, and M. Vincler The effect of peripherally administered CDP-choline in an acute inflammatory pain model: the role of alpha7 nicotinic acetylcholine receptor Anesth. Analg. 108 2009 1680 1687
    • (2009) Anesth. Analg. , vol.108 , pp. 1680-1687
    • Gurun, M.S.1    Parker, R.2    Eisenach, J.C.3    Vincler, M.4
  • 15
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • K. Hargreaves, R. Dubner, F. Brown, C. Flores, and J. Joris A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia Pain 32 1988 77 88
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 16
    • 78651317992 scopus 로고    scopus 로고
    • Alpha4beta2 nicotinic receptors partially mediate anti-inflammatory effects through Janus kinase 2-signal transducer and activator of transcription 3 but not calcium or cAMP signaling
    • V. Hosur, and R.H. Loring Alpha4beta2 nicotinic receptors partially mediate anti-inflammatory effects through Janus kinase 2-signal transducer and activator of transcription 3 but not calcium or cAMP signaling Mol. Pharmacol. 79 2011 167 174
    • (2011) Mol. Pharmacol. , vol.79 , pp. 167-174
    • Hosur, V.1    Loring, R.H.2
  • 17
    • 70450212126 scopus 로고    scopus 로고
    • Microglia and neuropathic pain
    • K. Inoue, and M. Tsuda Microglia and neuropathic pain Glia 57 2009 1469 1479
    • (2009) Glia , vol.57 , pp. 1469-1479
    • Inoue, K.1    Tsuda, M.2
  • 18
    • 84857236125 scopus 로고    scopus 로고
    • Chemokines and cytokines in neuroinflammation leading to neuropathic pain
    • N. Kiguchi, Y. Kobayashi, and S. Kishioka Chemokines and cytokines in neuroinflammation leading to neuropathic pain Curr. Opin. Pharmacol. 12 2012 55 61
    • (2012) Curr. Opin. Pharmacol. , vol.12 , pp. 55-61
    • Kiguchi, N.1    Kobayashi, Y.2    Kishioka, S.3
  • 19
    • 84857315556 scopus 로고    scopus 로고
    • Epigenetic augmentation of the macrophage inflammatory protein 2/C-X-C chemokine receptor type 2 axis through histone H3 acetylation in injured peripheral nerves elicits neuropathic pain
    • N. Kiguchi, Y. Kobayashi, T. Maeda, Y. Fukazawa, K. Tohya, and M. Kimura Epigenetic augmentation of the macrophage inflammatory protein 2/C-X-C chemokine receptor type 2 axis through histone H3 acetylation in injured peripheral nerves elicits neuropathic pain J. Pharmacol. Exp. Ther. 340 2012 577 587
    • (2012) J. Pharmacol. Exp. Ther. , vol.340 , pp. 577-587
    • Kiguchi, N.1    Kobayashi, Y.2    Maeda, T.3    Fukazawa, Y.4    Tohya, K.5    Kimura, M.6
  • 20
    • 77951764686 scopus 로고    scopus 로고
    • Macrophage inflammatory protein-1alpha mediates the development of neuropathic pain following peripheral nerve injury through interleukin-1beta up-regulation
    • N. Kiguchi, T. Maeda, Y. Kobayashi, Y. Fukazawa, and S. Kishioka Macrophage inflammatory protein-1alpha mediates the development of neuropathic pain following peripheral nerve injury through interleukin-1beta up-regulation Pain 149 2010 305 315
    • (2010) Pain , vol.149 , pp. 305-315
    • Kiguchi, N.1    Maeda, T.2    Kobayashi, Y.3    Fukazawa, Y.4    Kishioka, S.5
  • 21
    • 44449148469 scopus 로고    scopus 로고
    • Involvement of spinal Met-enkephalin in nicotine-induced antinociception in mice
    • N. Kiguchi, T. Maeda, M. Tsuruga, A. Yamamoto, C. Yamamoto, and M. Ozaki Involvement of spinal Met-enkephalin in nicotine-induced antinociception in mice Brain Res. 1189 2008 70 77
    • (2008) Brain Res. , vol.1189 , pp. 70-77
    • Kiguchi, N.1    Maeda, T.2    Tsuruga, M.3    Yamamoto, A.4    Yamamoto, C.5    Ozaki, M.6
  • 22
    • 77949329326 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors: New insights into cancer-related inflammation
    • G. Lazennec, and A. Richmond Chemokines and chemokine receptors: new insights into cancer-related inflammation Trends Mol. Med. 16 2010 133 144
    • (2010) Trends Mol. Med. , vol.16 , pp. 133-144
    • Lazennec, G.1    Richmond, A.2
  • 23
    • 77954215043 scopus 로고    scopus 로고
    • Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats
    • L.C. Loram, J.A. Harrison, L. Chao, F.R. Taylor, A. Reddy, and C.L. Travis Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats Brain Behav. Immun. 24 2010 959 967
    • (2010) Brain Behav. Immun. , vol.24 , pp. 959-967
    • Loram, L.C.1    Harrison, J.A.2    Chao, L.3    Taylor, F.R.4    Reddy, A.5    Travis, C.L.6
  • 24
    • 33745115627 scopus 로고    scopus 로고
    • Increased calcitonin gene-related peptide in neuroma and invading macrophages is involved in the up-regulation of interleukin-6 and thermal hyperalgesia in a rat model of mononeuropathy
    • W. Ma, and R. Quirion Increased calcitonin gene-related peptide in neuroma and invading macrophages is involved in the up-regulation of interleukin-6 and thermal hyperalgesia in a rat model of mononeuropathy J. Neurochem. 98 2006 180 192
    • (2006) J. Neurochem. , vol.98 , pp. 180-192
    • Ma, W.1    Quirion, R.2
  • 25
    • 69149085109 scopus 로고    scopus 로고
    • Leptin derived from adipocytes in injured peripheral nerves facilitates development of neuropathic pain via macrophage stimulation
    • T. Maeda, N. Kiguchi, Y. Kobayashi, T. Ikuta, M. Ozaki, and S. Kishioka Leptin derived from adipocytes in injured peripheral nerves facilitates development of neuropathic pain via macrophage stimulation Proc. Natl. Acad. Sci. USA 106 2009 13076 13081
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 13076-13081
    • Maeda, T.1    Kiguchi, N.2    Kobayashi, Y.3    Ikuta, T.4    Ozaki, M.5    Kishioka, S.6
  • 26
    • 79953805191 scopus 로고    scopus 로고
    • Neural systems governed by nicotinic acetylcholine receptors: Emerging hypotheses
    • J.M. Miwa, R. Freedman, and H.A. Lester Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses Neuron 70 2011 20 33
    • (2011) Neuron , vol.70 , pp. 20-33
    • Miwa, J.M.1    Freedman, R.2    Lester, H.A.3
  • 28
    • 33645237919 scopus 로고    scopus 로고
    • Anti-inflammatory properties of cholinergic up-regulation: A new role for acetylcholinesterase inhibitors
    • E. Nizri, Y. Hamra-Amitay, C. Sicsic, I. Lavon, and T. Brenner Anti-inflammatory properties of cholinergic up-regulation: a new role for acetylcholinesterase inhibitors Neuropharmacology 50 2006 540 547
    • (2006) Neuropharmacology , vol.50 , pp. 540-547
    • Nizri, E.1    Hamra-Amitay, Y.2    Sicsic, C.3    Lavon, I.4    Brenner, T.5
  • 29
    • 77649341442 scopus 로고    scopus 로고
    • Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses
    • E. Nizri, M. Irony-Tur-Sinai, O. Lory, A. Orr-Urtreger, E. Lavi, and T. Brenner Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses J. Immunol. 183 2009 6681 6688
    • (2009) J. Immunol. , vol.183 , pp. 6681-6688
    • Nizri, E.1    Irony-Tur-Sinai, M.2    Lory, O.3    Orr-Urtreger, A.4    Lavi, E.5    Brenner, T.6
  • 31
    • 84865654979 scopus 로고    scopus 로고
    • Alpha7nAChR Expression in Bone-Marrow Derived non T Cells is Required for the Inflammatory Reflex
    • P. Olofsson, D. Katz, M. Rosas-Ballina, Y. Levine, M. Ochani, and S. Valdes-Ferrer Alpha7nAChR Expression in Bone-Marrow Derived non T Cells is Required for the Inflammatory Reflex Mol. Med. 18 2012 539 543
    • (2012) Mol. Med. , vol.18 , pp. 539-543
    • Olofsson, P.1    Katz, D.2    Rosas-Ballina, M.3    Levine, Y.4    Ochani, M.5    Valdes-Ferrer, S.6
  • 32
    • 70449525704 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors: Standing at the crossroads of immunobiology and neurobiology
    • R.M. Ransohoff Chemokines and chemokine receptors: standing at the crossroads of immunobiology and neurobiology Immunity 31 2009 711 721
    • (2009) Immunity , vol.31 , pp. 711-721
    • Ransohoff, R.M.1
  • 33
    • 0037145712 scopus 로고    scopus 로고
    • Neuropathy-specific analgesic action of intrathecal nicotinic agonists and its spinal GABA-mediated mechanism
    • M.H. Rashid, and H. Ueda Neuropathy-specific analgesic action of intrathecal nicotinic agonists and its spinal GABA-mediated mechanism Brain Res. 953 2002 53 62
    • (2002) Brain Res. , vol.953 , pp. 53-62
    • Rashid, M.H.1    Ueda, H.2
  • 34
    • 78149357276 scopus 로고    scopus 로고
    • Interactions between the immune and nervous systems in pain
    • K. Ren, and R. Dubner Interactions between the immune and nervous systems in pain Nat. Med. 16 2010 1267 1276
    • (2010) Nat. Med. , vol.16 , pp. 1267-1276
    • Ren, K.1    Dubner, R.2
  • 35
    • 17144370981 scopus 로고    scopus 로고
    • Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation
    • R.W. Saeed, S. Varma, T. Peng-Nemeroff, B. Sherry, D. Balakhaneh, and J. Huston Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation J. Exp. Med. 201 2005 1113 1123
    • (2005) J. Exp. Med. , vol.201 , pp. 1113-1123
    • Saeed, R.W.1    Varma, S.2    Peng-Nemeroff, T.3    Sherry, B.4    Balakhaneh, D.5    Huston, J.6
  • 36
    • 33744727277 scopus 로고    scopus 로고
    • Loss of tumor necrosis factor alpha potentiates transforming growth factor beta-mediated pathogenic tissue response during wound healing
    • S. Saika, K. Ikeda, O. Yamanaka, K.C. Flanders, Y. Okada, and T. Miyamoto Loss of tumor necrosis factor alpha potentiates transforming growth factor beta-mediated pathogenic tissue response during wound healing Am. J. Pathol. 168 2006 1848 1860
    • (2006) Am. J. Pathol. , vol.168 , pp. 1848-1860
    • Saika, S.1    Ikeda, K.2    Yamanaka, O.3    Flanders, K.C.4    Okada, Y.5    Miyamoto, T.6
  • 37
    • 35548937457 scopus 로고    scopus 로고
    • The neuropathic pain triad: Neurons, immune cells and glia
    • J. Scholz, and C.J. Woolf The neuropathic pain triad: neurons, immune cells and glia Nat. Neurosci. 10 2007 1361 1368
    • (2007) Nat. Neurosci. , vol.10 , pp. 1361-1368
    • Scholz, J.1    Woolf, C.J.2
  • 38
    • 0025167399 scopus 로고
    • A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury
    • Z. Seltzer, R. Dubner, and Y. Shir A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury Pain 43 1990 205 218
    • (1990) Pain , vol.43 , pp. 205-218
    • Seltzer, Z.1    Dubner, R.2    Shir, Y.3
  • 39
    • 11144355227 scopus 로고    scopus 로고
    • Cholinergic modulation of microglial activation by alpha 7 nicotinic receptors
    • R.D. Shytle, T. Mori, K. Townsend, M. Vendrame, N. Sun, and J. Zeng Cholinergic modulation of microglial activation by alpha 7 nicotinic receptors J. Neurochem. 89 2004 337 343
    • (2004) J. Neurochem. , vol.89 , pp. 337-343
    • Shytle, R.D.1    Mori, T.2    Townsend, K.3    Vendrame, M.4    Sun, N.5    Zeng, J.6
  • 40
    • 34548137358 scopus 로고    scopus 로고
    • Pathophysiology of peripheral neuropathic pain: Immune cells and molecules
    • M.A. Thacker, A.K. Clark, F. Marchand, and S.B. McMahon Pathophysiology of peripheral neuropathic pain: immune cells and molecules Anesth. Analg. 105 2007 838 847
    • (2007) Anesth. Analg. , vol.105 , pp. 838-847
    • Thacker, M.A.1    Clark, A.K.2    Marchand, F.3    McMahon, S.B.4
  • 41
    • 0036703899 scopus 로고    scopus 로고
    • Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF
    • G.K. Tofaris, P.H. Patterson, K.R. Jessen, and R. Mirsky Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF J. Neurosci. 22 2002 6696 6703
    • (2002) J. Neurosci. , vol.22 , pp. 6696-6703
    • Tofaris, G.K.1    Patterson, P.H.2    Jessen, K.R.3    Mirsky, R.4
  • 42
    • 33846817498 scopus 로고    scopus 로고
    • Physiology and immunology of the cholinergic antiinflammatory pathway
    • K.J. Tracey Physiology and immunology of the cholinergic antiinflammatory pathway J. Clin. Invest. 117 2007 289 296
    • (2007) J. Clin. Invest. , vol.117 , pp. 289-296
    • Tracey, K.J.1
  • 43
    • 9144263639 scopus 로고    scopus 로고
    • Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
    • H. Wang, H. Liao, M. Ochani, M. Justiniani, X. Lin, and L. Yang Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis Nat. Med. 10 2004 1216 1221
    • (2004) Nat. Med. , vol.10 , pp. 1216-1221
    • Wang, H.1    Liao, H.2    Ochani, M.3    Justiniani, M.4    Lin, X.5    Yang, L.6
  • 44
    • 0037461768 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation
    • H. Wang, M. Yu, M. Ochani, C.A. Amella, M. Tanovic, and S. Susarla Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation Nature 421 2003 384 388
    • (2003) Nature , vol.421 , pp. 384-388
    • Wang, H.1    Yu, M.2    Ochani, M.3    Amella, C.A.4    Tanovic, M.5    Susarla, S.6
  • 45
    • 79951875569 scopus 로고    scopus 로고
    • Activation of the cholinergic antiinflammatory pathway ameliorates obesity-induced inflammation and insulin resistance
    • X. Wang, Z. Yang, B. Xue, and H. Shi Activation of the cholinergic antiinflammatory pathway ameliorates obesity-induced inflammation and insulin resistance Endocrinology 152 2011 836 846
    • (2011) Endocrinology , vol.152 , pp. 836-846
    • Wang, X.1    Yang, Z.2    Xue, B.3    Shi, H.4
  • 46
    • 0031032949 scopus 로고    scopus 로고
    • Presynaptic nicotinic ACh receptors
    • S. Wonnacott Presynaptic nicotinic ACh receptors Trends Neurosci. 20 1997 92 98
    • (1997) Trends Neurosci. , vol.20 , pp. 92-98
    • Wonnacott, S.1
  • 47
    • 84855744762 scopus 로고    scopus 로고
    • Pharmacological relationship between nicotinic and opioid systems in analgesia and corticosterone elevation
    • A. Yamamoto, N. Kiguchi, Y. Kobayashi, T. Maeda, K. Ueno, and C. Yamamoto Pharmacological relationship between nicotinic and opioid systems in analgesia and corticosterone elevation Life Sci. 89 2011 956 961
    • (2011) Life Sci. , vol.89 , pp. 956-961
    • Yamamoto, A.1    Kiguchi, N.2    Kobayashi, Y.3    Maeda, T.4    Ueno, K.5    Yamamoto, C.6


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