Increased calcitonin gene-related peptide in neuroma and invading macrophages is involved in the up-regulation of interleukin-6 and thermal hyperalgesia in a rat model of mononeuropathy

Journal of Neurochemistry

Volumn 98, Issue 1, 2006, Pages 180-192

  Ma, Weiya ^a   Quirion, Remi ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

CGRP; Interleukin 6; Neuroimmune interaction; Neuropathic pain; Neuropeptide; Sciatic nerve

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONIST; CGRP 8 37; INTERLEUKIN 6; OLCEGEPANT; RECEPTOR ACTIVITY MODIFYING PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE RELEASE; EXPLANT; HYPERALGESIA; IMMUNOREACTIVITY; MACROPHAGE; MALE; MONONEUROPATHY; NERVE INJURY; NERVE LIGATION; NEUROMA; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; SCIATIC NERVE;

ANIMALS; BLOTTING, WESTERN; CALCITONIN GENE-RELATED PEPTIDE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ECTODYSPLASINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; MACROPHAGES; MALE; MEMBRANE PROTEINS; NEUROMA; PAIN MEASUREMENT; PIPERAZINES; QUINAZOLINES; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; SCIATIC NEUROPATHY; TUMOR NECROSIS FACTORS; UP-REGULATION;

EID: 33745115627     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03856.x     Document Type: Article

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