Insight into the structure-function relationship of the nonheme iron halogenases involved in the biosynthesis of 4-chlorothreonine - Thr3 from Streptomyces sp. OH-5093 and SyrB2 from Pseudomonas syringae pv. syringae B301DR

FEBS Journal

Volumn 279, Issue 23, 2012, Pages 4269-4282

  Fullone, Maria Rosaria ^a   Paiardini, Alessandro ^a   Miele, Rossella ^a   Marsango, Sara ^a   Gross, Dennis C ^b   Omura, Satoshi ^c   Ros Herrera, Enric ^a   Bonaccorsi Di Patti, Maria Carmela ^a   Laganà, Aldo ^a   Pascarella, Stefano ^a   Grgurina, Ingeborg ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b TEXAS A AND M UNIVERSITY   (United States)

^c KITASATO UNIVERSITY   (Japan)

Author keywords

4 chlorothreonine gene cluster; Fe(II) nonheme ketoglutarate halogenase; Pseudomonas syringae pv. syringae B301DR; Streptomyces sp. OH 5093; structure function relationship

Indexed keywords

2 OXOGLUTARIC ACID; 4 CHLOROTHREONINE; BACTERIAL ENZYME; ENZYME SYRB2; GENOMIC DNA; IRON OXIDE; SYRINGOMYCIN; THIOL ESTER HYDROLASE; THREONINE; THREONINE TRANSFER RNA LIGASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SYNTHESIS; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME STRUCTURE; GENETIC COMPLEMENTATION; HALOGENATION; NONHUMAN; NUCLEOTIDE SEQUENCE; ORF1 GENE; ORF2 GENE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PSEUDOMONAS SYRINGAE; SITE DIRECTED MUTAGENESIS; STREPTOMYCES; STRUCTURE ACTIVITY RELATION; SYRB2 GENE; THR1 GENE; THR2 GENE; THR3 GENE; THR4 GENE;

BACTERIAL PROTEINS; COMPUTATIONAL BIOLOGY; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTAGENESIS, SITE-DIRECTED; PSEUDOMONAS SYRINGAE; STREPTOMYCES; STRUCTURE-ACTIVITY RELATIONSHIP; THREONINE;

PSEUDOMONAS SYRINGAE PV. SYRINGAE; STREPTOMYCES SP.;

EID: 84870062977     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12017     Document Type: Article

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