Delivery of siRNA silencing Runx2 using a multifunctional polymer-lipid nanoparticle inhibits osteogenesis in a cell culture model of heterotopic ossification

Integrative Biology (United Kingdom)

Volumn 4, Issue 12, 2012, Pages 1498-1507

  Mishra, Swati ^a   Vaughn, Asa D ^b   Devore, David I ^b   Roth, Charles M ^a,c  

^a RUTGERS UNIVERSITY   (United States)

^b US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

^c The State University of New Jersey   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; CALCIUM PHOSPHATE; COPOLYMER; LIPOSOME; MESSENGER RNA; NANOCOMPOSITE; NANOPARTICLE; POLY(PROPYLACRYLIC ACID); POLYETHERAMINE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CELL CULTURE; CELL DIFFERENTIATION; CELL FATE; CELL PROTECTION; COMPLEX FORMATION; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVITY; GENE; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; HETEROTOPIC OSSIFICATION; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; RNA SEQUENCE; RNA STRUCTURE; RUNX2 GENE; ZETA POTENTIAL;

ACRYLATES; ALKALINE PHOSPHATASE; ANIMALS; BASE SEQUENCE; BONE MORPHOGENETIC PROTEIN 2; CALCIFICATION, PHYSIOLOGIC; CALCIUM PHOSPHATES; CELL LINE; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DRUG DELIVERY SYSTEMS; FATTY ACIDS, MONOUNSATURATED; LIPOSOMES; MICE; MODELS, BIOLOGICAL; MYOBLASTS, SKELETAL; NANOCOMPOSITES; OSSIFICATION, HETEROTOPIC; OSTEOGENESIS; POLYAMINES; POLYMERS; QUATERNARY AMMONIUM COMPOUNDS; RNA, SMALL INTERFERING; SYSTEMS BIOLOGY;

EID: 84870044029     PISSN: 17579694     EISSN: 17579708     Source Type: Journal    
DOI: 10.1039/c2ib20200j     Document Type: Article

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