Non-virus-mediated transfer of siRNAs against Runx2 and Smad4 inhibit heterotopic ossification in rats

Gene Therapy

Volumn 17, Issue 3, 2010, Pages 370-379

  Xue, T ^a   Mao, Z ^b   Lin, L ^a   Hou, Y ^a   Wei, X ^c   Fu, X ^a   Zhang, J ^a   Yu, C ^a  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c TIANJIN HOSPITAL   (China)

Author keywords

Heterotopic ossification; Non virus; Runx2; SiRNA; Smad4

Indexed keywords

MESSENGER RNA; SMAD4 PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; GENE EXPRESSION; GENETIC TRANSFECTION; HETEROTOPIC OSSIFICATION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE;

ACHILLES TENDON; ANIMALS; CORE BINDING FACTOR ALPHA 1 SUBUNIT; GENE THERAPY; GENE TRANSFER TECHNIQUES; MALE; OSSIFICATION, HETEROTOPIC; RATS; RNA, SMALL INTERFERING; SMAD4 PROTEIN;

RATTUS;

EID: 77949425482     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2009.154     Document Type: Article

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