Regulation of JAK2 activation by Janus homology 2: Evidence from molecular dynamics simulations

Journal of Chemical Information and Modeling

Volumn 52, Issue 11, 2012, Pages 2992-3000

  Wan, Shunzhou ^a   Coveney, Peter V ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMICAL ACTIVATION; DIMERS; ENZYMES;

ASYMMETRIC DIMERS; CYTOKINE RECEPTOR; DOMAIN-DOMAIN INTERACTIONS; ENERGETIC PROPERTIES; MOLECULAR DYNAMICS SIMULATIONS; PROTEIN TYROSINE KINASE; STRUCTURAL MODELING; STRUCTURAL REARRANGEMENT;

MOLECULAR DYNAMICS;

ADENOSINE TRIPHOSPHATE; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR; JAK2 PROTEIN, HUMAN; JANUS KINASE 2;

ARTICLE; CHEMISTRY; ENZYME ACTIVATION; GENETICS; HUMAN; KINETICS; MOLECULAR DYNAMICS; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; STRUCTURAL HOMOLOGY; THERMODYNAMICS;

ADENOSINE TRIPHOSPHATE; ENZYME ACTIVATION; HUMANS; JANUS KINASE 2; KINETICS; MOLECULAR DYNAMICS SIMULATION; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR; STRUCTURAL HOMOLOGY, PROTEIN; THERMODYNAMICS;

EID: 84870009088     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci300308g     Document Type: Article

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