-
1
-
-
62649159075
-
Ligand-induced ErbB receptor dimerization
-
Lemmon MA (2009) Ligand-induced ErbB receptor dimerization. Exp Cell Res 315:638-648.
-
(2009)
Exp Cell Res
, vol.315
, pp. 638-648
-
-
Lemmon, M.A.1
-
2
-
-
18344390418
-
ERBB receptors and cancer: The complexity of targeted inhibitors
-
DOI 10.1038/nrc1609
-
Hynes NE, Lane HA (2005) ErbB receptors and cancer: The complexity of targeted inhibitors. Nat Rev Cancer 5:341-354. (Pubitemid 40637826)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
3
-
-
48249158391
-
Structure-based view of epidermal growth factor receptor regulation
-
Ferguson KM (2008) Structure-based view of epidermal growth factor receptor regulation. Annu Rev Biophys 37:353-373.
-
(2008)
Annu Rev Biophys
, vol.37
, pp. 353-373
-
-
Ferguson, K.M.1
-
4
-
-
63049100044
-
Functional selectivity of EGF family peptide growth factors: Implications for cancer
-
Wilson KJ, et al. (2009) Functional selectivity of EGF family peptide growth factors: Implications for cancer. Pharmacol Ther 122:1-8.
-
(2009)
Pharmacol Ther
, vol.122
, pp. 1-8
-
-
Wilson, K.J.1
-
5
-
-
0037434791
-
Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
-
DOI 10.1038/nature01392
-
Cho H-S, et al. (2003) Structure of the extracellular region of HER2 alone and in complex with the herceptin Fab. Nature 421:756-760. (Pubitemid 36227628)
-
(2003)
Nature
, vol.421
, Issue.6924
, pp. 756-760
-
-
Cho, H.-S.1
Mason, K.2
Ramyar, K.X.3
Stanley, A.M.4
Gabelli, S.B.5
Denney Jr., D.W.6
Leahy, D.J.7
-
6
-
-
0033608993
-
The ErbB2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derive growth factors
-
Klapper LN (1999) The ErbB2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derive growth factors. Proc Natl Acad Sci USA 96:4995-5000.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 4995-5000
-
-
Klapper, L.N.1
-
7
-
-
0030944455
-
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
-
DOI 10.1093/emboj/16.7.1647
-
Graus Porta D, Beerli RR, Daly JM, Hynes NE (1997) ErbB2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J 16:1647-1655. (Pubitemid 27151960)
-
(1997)
EMBO Journal
, vol.16
, Issue.7
, pp. 1647-1655
-
-
Graus-Porta, D.1
Beerli, R.R.2
Daly, J.M.3
Hynes, N.E.4
-
8
-
-
0029814271
-
A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor
-
Tzahar E, et al. (1996) A Hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol Cell Biol 16:5276-5287. (Pubitemid 26315047)
-
(1996)
Molecular and Cellular Biology
, vol.16
, Issue.10
, pp. 5276-5287
-
-
Tzahar, E.1
Waterman, H.2
Chen, X.3
Levkowitz, G.4
Karunagaran, D.5
Lavi, S.6
Ratzkin, B.J.7
Yarden, Y.8
-
9
-
-
67449146917
-
The juxtamembrane region of the EGF receptor functions as an activation domain
-
Brewer MR, et al. (2009) The juxtamembrane region of the EGF receptor functions as an activation domain. Mol Cell 34:641-651.
-
(2009)
Mol Cell
, vol.34
, pp. 641-651
-
-
Brewer, M.R.1
-
10
-
-
67549145398
-
Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment
-
Jura N, et al. (2009) Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell 137:1293-1307.
-
(2009)
Cell
, vol.137
, pp. 1293-1307
-
-
Jura, N.1
-
11
-
-
33745002702
-
An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
-
DOI 10.1016/j.cell.2006.05.013, PII S0092867406005848
-
Zhang X, et al. (2006) An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell 125:1137-1149. (Pubitemid 43866200)
-
(2006)
Cell
, vol.125
, Issue.6
, pp. 1137-1149
-
-
Zhang, X.1
Gureasko, J.2
Shen, K.3
Cole, P.A.4
Kuriyan, J.5
-
12
-
-
0029029617
-
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
-
Jeffrey PD, et al. (1995) Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature 376:313-320.
-
(1995)
Nature
, vol.376
, pp. 313-320
-
-
Jeffrey, P.D.1
-
13
-
-
77951248565
-
Her4 and Her2/neu tyrosine kinase domains dimerize and activate in a reconstituted in vitro system
-
Monsey J, Shen W, Schlesinger P, Bose R (2010) Her4 and Her2/neu tyrosine kinase domains dimerize and activate in a reconstituted in vitro system. J Biol Chem 285:7035-7044.
-
(2010)
J Biol Chem
, vol.285
, pp. 7035-7044
-
-
Monsey, J.1
Shen, W.2
Schlesinger, P.3
Bose, R.4
-
14
-
-
65549138069
-
Luciferase fragment complementation imaging of conformational changes in the EGF receptor
-
Yang KS, Ilagan MXG, Piwnica-Worms D, Pike LJ (2009) Luciferase fragment complementation imaging of conformational changes in the EGF receptor. J Biol Chem 284:7474-7482.
-
(2009)
J Biol Chem
, vol.284
, pp. 7474-7482
-
-
Yang, K.S.1
Ilagan, M.X.G.2
Piwnica-Worms, D.3
Pike, L.J.4
-
15
-
-
77954900212
-
Asp-960/Glu-961 Control the movement of the C-terminal tail of the EGF receptor to regulate asymmetric dimer formation
-
Yang KS, Macdonald-Obermann JL, Piwnica-Worms D, Pike LJ (2010) Asp-960/Glu-961 Control the movement of the C-terminal tail of the EGF receptor to regulate asymmetric dimer formation. J Biol Chem 285:24014-24022.
-
(2010)
J Biol Chem
, vol.285
, pp. 24014-24022
-
-
Yang, K.S.1
Macdonald-Obermann, J.L.2
Piwnica-Worms, D.3
Pike, L.J.4
-
16
-
-
24044436190
-
Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis
-
DOI 10.1074/jbc.M504770200
-
Clayton AHA, et al. (2005) Ligand-induced dimer-tetramer transition during the activation of cell surface epidermal growth factor receptor. A Multidimensional microscopy analysis. J Biol Chem 280:30392-30399. (Pubitemid 41216222)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.34
, pp. 30392-30399
-
-
Clayton, A.H.A.1
Walker, F.2
Orchard, S.G.3
Henderson, C.4
Fuchs, D.5
Rothacker, J.6
Nice, E.C.7
Burgess, A.W.8
-
17
-
-
0036225144
-
Preformed oligomeric epidermal growth factor receptors undergo an ectodomain structure change during signaling
-
Martin-Fernandez M, et al. (2002) Preformed oligomeric epidermal growth factor receptors undergo and ectodomain structure change during signaling. Biophys J 82:2415-2427. (Pubitemid 34441281)
-
(2002)
Biophysical Journal
, vol.82
, Issue.5
, pp. 2415-2427
-
-
Martin-Fernandez, M.1
Clarke, D.T.2
Tobin, M.J.3
Jones, S.V.4
Jones, G.R.5
-
18
-
-
0033779765
-
Single-molecule imaging of EGFR signalling on the surface of living cells
-
Sako Y, Minoguchi S, Yanagida T (2000) Single-molecule imaging of EGFR signalling on the surface of living cells. Nat Cell Biol 2:168-172.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 168-172
-
-
Sako, Y.1
Minoguchi, S.2
Yanagida, T.3
-
19
-
-
55449102296
-
All EGF (ErbB) receptors have preformed homo- And heterodimeric structures in living cells
-
Tao R-H, Maruyama IN (2008) All EGF (ErbB) receptors have preformed homo- and heterodimeric structures in living cells. J Cell Sci 121:3207-3217.
-
(2008)
J Cell Sci
, vol.121
, pp. 3207-3217
-
-
Tao, R.-H.1
Maruyama, I.N.2
-
20
-
-
0036320471
-
Ligand-independent dimer formation of epidermal growth factor receptor (EGFR) is a step separable from ligand-induced EGFR signaling
-
DOI 10.1091/mbc.01-08-0411
-
Yu X, et al. (2002) Ligand-independent dimer formation of epidermal growth factor receptor (EGFR) is a step separable from ligand-induced EGFR signaling. Mol Biol Cell 13:2547-2557. (Pubitemid 34831354)
-
(2002)
Molecular Biology of the Cell
, vol.13
, Issue.7
, pp. 2547-2557
-
-
Yu, X.1
Sharma, K.D.2
Takahashi, T.3
Iwamoto, R.4
Mekada, E.5
-
21
-
-
4344656346
-
Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals
-
DOI 10.1073/pnas.0404041101
-
Luker KE, et al. (2004) Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals. Proc Natl Acad Sci USA 101:12288-12293. (Pubitemid 39145436)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.33
, pp. 12288-12293
-
-
Luker, K.E.1
Smith, M.C.P.2
Luker, G.D.3
Gammon, S.T.4
Piwnica-Worms, H.5
Piwnica-Worms, D.6
-
22
-
-
35348813658
-
Current state of imaging protein-protein interactions in vivo with genetically encoded reporters
-
DOI 10.1146/annurev.bioeng.9.060906.152044
-
Villalobos VM, Naik S, Piwnica-Worms D (2007) Current state of imaging protein-protein interactions in vivo with genetically encoded reporters. Annu Rev Biomed Eng 9:321-349. (Pubitemid 350246660)
-
(2007)
Annual Review of Biomedical Engineering
, vol.9
, pp. 321-349
-
-
Villalobos, V.1
Naik, S.2
Piwnica-Worms, D.3
-
23
-
-
0141599428
-
Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor
-
DOI 10.1074/jbc.M207135200
-
Stamos J, Sliwkowski MX, Eigenbrot C (2002) Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor. J Biol Chem 277:46265-46272. (Pubitemid 35417619)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.48
, pp. 46265-46272
-
-
Stamos, J.1
Sliwkowski, M.X.2
Eigenbrot, C.3
-
24
-
-
84455161571
-
The membrane-proximal intracellular domain of the EGF receptor underlies negative cooperativity in ligand binding
-
10.1074/jbc.M111.274175
-
Adak S, Yang KS, Macdonald-Obermann JL, Pike LJ (2011) The membrane-proximal intracellular domain of the EGF receptor underlies negative cooperativity in ligand binding. J Biol Chem, 10.1074/jbc.M111.274175.
-
(2011)
J Biol Chem
-
-
Adak, S.1
Yang, K.S.2
Macdonald-Obermann, J.L.3
Pike, L.J.4
-
25
-
-
0028168569
-
Insect cell-expressed p180ErbB3 possesses an impaired tyrosine kinase activity
-
Guy PM, et al. (1994) Insect cell-expressed p180ErbB3 possesses an impaired tyrosine kinase activity. Proc Natl Acad Sci USA 91:8132-8136.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8132-8136
-
-
Guy, P.M.1
-
26
-
-
77952338791
-
ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation
-
Shi F, et al. (2010) ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation. Proc Natl Acad Sci USA 107:7692-7697.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7692-7697
-
-
Shi, F.1
-
27
-
-
0035979763
-
Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain
-
DOI 10.1006/jmbi.2001.4923
-
Moriki T, Maruyama H, Maruyama IN (2001) Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain. J Mol Biol 311:1011-1026. (Pubitemid 32803717)
-
(2001)
Journal of Molecular Biology
, vol.311
, Issue.5
, pp. 1011-1026
-
-
Moriki, T.1
Maruyama, H.2
Maruyama, I.N.3
-
28
-
-
34447313361
-
Oligomerization of the EGF receptor investigated by live cell fluorescence intensity distribution analysis
-
DOI 10.1529/biophysj.107.105494
-
Saffarian S, Li Y, Elson EL, Pike LJ (2007) Oligomerization of the EGF receptor investigated by live cell fluorescence intensity distribution analysis. Biophys J 93:1021-1031. (Pubitemid 47219793)
-
(2007)
Biophysical Journal
, vol.93
, Issue.3
, pp. 1021-1031
-
-
Saffarian, S.1
Li, Y.2
Elson, E.L.3
Pikey, L.J.4
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