Oral Administration of Puerh Tea Polysaccharides Lowers Blood Glucose Levels and Enhances Antioxidant Status in Alloxan-Induced Diabetic Mice

Journal of Food Science

Volumn 77, Issue 11, 2012, Pages

  Xu, Ping ^a,b   Chen, Hao ^a   Wang, Yiqi ^b,c   Hochstetter, Danielle ^a   Zhou, Tao ^a   Wang, Yuefei ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b BEIJING HOSPITAL   (China)

^c ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

Antioxidant; Blood glucose; Diabetes; Polysaccharides; Puerh tea

Indexed keywords

ANTIDIABETIC AGENT; ANTIOXIDANT; MALONALDEHYDE; METFORMIN; PLANT EXTRACT; POLYSACCHARIDE; SUPEROXIDE DISMUTASE;

ANIMAL; ARTICLE; BLOOD; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; INSTITUTE FOR CANCER RESEARCH MOUSE; LIVER; MALE; METABOLISM; MOUSE; ORAL DRUG ADMINISTRATION; OXIDATIVE STRESS; TEA;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; HYPOGLYCEMIC AGENTS; LIVER; MALE; MALONDIALDEHYDE; METFORMIN; MICE; MICE, INBRED ICR; OXIDATIVE STRESS; PLANT EXTRACTS; POLYSACCHARIDES; SUPEROXIDE DISMUTASE; TEA;

MUS;

EID: 84869869955     PISSN: 00221147     EISSN: 17503841     Source Type: Journal    
DOI: 10.1111/j.1750-3841.2012.02950.x     Document Type: Article

References (25)

1. Chen H, Zhang M, Xie B. 2004. Quantification of uronic acids in tea polysaccharide conjugates and their antioxidant properties. J Agric Food Chem 52(11):3333-6.
2. Chen H, Xu Z, Xu N, Cen P. 2005. Efficient production of a soluble fusion protein containing human beta-defensin-2 in E. coli cell-free system. J Biotechnol 115:307-15.
3. Chen H, Qu Z, Fu L, Dong P, Zhang X. 2009. Physicochemical properties and antioxidant capacity of 3 polysaccharides from green tea, oolong tea, and black tea. J Food Sci 74(6):C469-74.
4. Chen X, Lin Z, Ye Y, Zhang R, Yin J, Jiang Y, Wan H. 2010. Suppression of diabetes in non-obese diabetic (NOD) mice by oral administration of water-soluble and alkali-soluble polysaccharide conjugates prepared from green tea. Carbohydr Polym 82(1):28-33.
5. Ghosh T, Chattopadhyay K, Marschall M, Karmakar P, Mandal P, Ray B. 2009. Focus on antivirally active sulfated polysaccharides: from structure-activity analysis to clinical evaluation. Glycobiology 19(1):2-15.
6. Hou Y, Shao W, Xiao R, Xu R, Ma Z, Johnstone BH, Du Y. 2009. Pu-erh tea aqueous extracts lower atherosclerotic risk factors in a rat hyperlipidemia model. Exp Gerontol 44(6):434-9.
7. Hui H, Tang G, Go VLW. 2009. Hypoglycemic herbs and their action mechanisms. Chinese Med 4(1):11.
8. Hwang HJ, Kim SW, Lim JM, Joo JH, Kim HO, Kim HM, Yun JW. 2005. Hypoglycemic effect of crude exopolysaccharides produced by a medicinal mushroom Phellinus baumii in streptozotocin-induced diabetic rats. Life Sci 76(26):3069-80.
9. International Diabetes Federation. 2011. Available from: http://www.idf.org/diabetesatlas/5e/the-global-burden. Accessed Jan 15, 2012.
10. Jie G, Lin Z, Zhang L, Lv H, He P, Zhao B. 2006. Free radical scavenging effect of Pu-erh tea extracts and their protective effect on oxidative damage in human fibroblast cells. J Agric Food Chem 54(21):8058-64.
11. Lin JK, Lin-Shiau SY. 2006. Mechanisms of hypolipidemic and anti-obesity effects of tea and tea polyphenols. Mol Nutr Food Res 50(2):211-7.
12. Nie SP, Xie MY. 2011. A review on the isolation and structure of tea polysaccharides and their bioactivities. Food Hydrocolloid 25(2):144-9.
13. Rains JL, Jain SK. 2011. Oxidative stress, insulin signaling and diabetes. Free Radical Bio Med 50(5):567-75.
14. Saravanan R, Pari L. 2005. Antihyperlipidemic and antiperoxidative effect of Diasulin, a polyherbal formulation in alloxan induced hyperglycemic rats. BMC Complement Altern Med 5(1):14.
15. Schneider C, Segre T. 2009. Green tea: potential health benefits. Am Fam Physician 79(7):591-4.
16. Staob A. 1965. Removal of proteins from polysaccharides methods. Carbohydr Chem 5(5):1-5.
17. Tian L, Zhao Y, Guo C, Yang X. 2011. A comparative study on the antioxidant activities of an acidic polysaccharide and various solvent extracts derived from herbal Houttuynia cordata. Carbohydr Polym 83(2):537-44.
18. Wajchenberg BL. 2010. Clinical approaches to preserve β-Cell function in diabetes. Adv Exp Med Biol 654:515-35.
19. Wang D, Wang C, Li J, Zhao G. (2001). Components and activity of polysaccharides from coarse tea. J Agric Food Chem 49(1):507-10.
20. Wang Y, Shao S, Xu P, Chen H, Lin-Shiau SY, Deng YT, Lin JK. 2012. Fermentation process enhanced production and bioactivities of oolong tea polysaccharides. Food Res Int 46(1):58-166.
21. Wei W, Liu Q, Tan Y, Liu L, Li X, Cai L. 2009. Oxidative stress, diabetes, and diabetic complications. Hemoglobin 33(5):370-7.
22. Wei X, Chen M, Xiao J, Liu Y, Yu L, Zhang H, Wang Y. 2010. Composition and bioactivity of tea flower polysaccharides obtained by different methods. Carbohydr Polym 79(2):418-22.
23. Wu SC, Yen GC, Wang BS, Chiu CK, Yen WJ, Chang LW, Duh PD. 2007. Antimutagenic and antimicrobial activities of pu-erh tea. LWT-Food Sci Technol 40(3):506-12.
24. Xiao J, Huo J, Jiang H, Yang F. 2011. Chemical compositions and bioactivities of crude polysaccharides from tea leaves beyond their useful date. Int J Biol Macromol 49(5):1143-51.
25. Zhou X, Wang D, Sun P, Bucheli P, Li L, Hou Y, Wang J. 2007. Effects of soluble tea polysaccharides on hyperglycemia in alloxan-diabetic mice. J Agric Food Chem 55(14):5523-8.