Focus on antivirally active sulfated polysaccharides: From structure-activity analysis to clinical evaluation

Glycobiology

Volumn 19, Issue 1, 2009, Pages 2-15

  Ghosh, Tuhin ^a   Chattopadhyay, Kausik ^a   Marschall, Manfred ^b   Karmakar, Paramita ^a   Mandal, Pinaki ^a   Ray, Bimalendu ^a  

^a UNIVERSITY OF BURDWAN   (India)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Antiviral activity; Mechanisms; Structural diversity; Structure function relationship; Sulfated polysaccharides

Indexed keywords

ANTIINFECTIVE AGENT; ANTIVIRUS AGENT; CARRAGEENAN; CELL SURFACE RECEPTOR; CELLACEFATE; CELLULOSE SULFATE; CHONDROITIN SULFATE; CURDLAN; DEXTRAN SULFATE; DEXTRIN 2 SULFATE; DEXTRIN X SULFATE; GLYCOSAMINOGLYCAN; HEPARIN; MICROBICIDE; OLIGOSACCHARIDE; PC 815; POLYSACCHARIDE SULFATE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTICOAGULATION; ANTIVIRAL ACTIVITY; ANTIVIRAL SUSCEPTIBILITY; BINDING SITE; CHEMICAL MODIFICATION; CLINICAL TRIAL; DRUG ABSORPTION; DRUG DETERMINATION; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG ISOLATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SULFATION; DRUG SYNTHESIS; HERPES; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR WEIGHT; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SEXUALLY TRANSMITTED DISEASE; SIDE EFFECT; STRUCTURE ACTIVITY RELATION; VIRUS INFECTION; VIRUS TRANSMISSION;

ANTIVIRAL AGENTS; BINDING SITES; HIV-1; HYDROGEN BONDING; HYDROPHOBICITY; MODELS, MOLECULAR; MOLECULAR WEIGHT; POLYSACCHARIDES; PROTEIN CONFORMATION; RECEPTORS, CELL SURFACE; SIMPLEXVIRUS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFATES;

EID: 57649225479     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwn092     Document Type: Review

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